Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection

Schotter J, Kamp P-B, Becker A, Pühler A, Reiss G, Brückl H (2004)
BIOSENSORS & BIOELECTRONICS 19(10): 1149-1156.

Journal Article | Published | English

No fulltext has been uploaded

Author
; ; ; ; ;
Abstract
We present a comparative analysis of a magnetoresistive biosensor to standard fluorescent DNA detection. The biosensor consists of giant magnetoresistive (GMR) type Cu/Ni80Fe20 multilayers in the second antiferromagnetic coupling maximum. Each of the 206 elements of the magnetoresistive biosensor is patterned into a spiral-shaped line that can cover the area of a typical DNA spot (70 mum diameter). The probe DNA is assembled on top of the sensor elements in different concentrations ranging from 16 pg/mul to 10 ng/mul. Complementary biotin-labeled analyte DNA is hybridized to the probe DNA at a concentration of 10 ng/mul. A number of different commercially available magnetic microspheres are investigated to determine the most appropriate markers. The experimental comparison shows that the relative sensitivity of the magnetoresistive biosensor is superior to the fluorescent detection at low probe DNA concentrations. (C) 2003 Elsevier B.V. All rights reserved.
Publishing Year
ISSN
PUB-ID

Cite this

Schotter J, Kamp P-B, Becker A, Pühler A, Reiss G, Brückl H. Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection. BIOSENSORS & BIOELECTRONICS. 2004;19(10):1149-1156.
Schotter, J., Kamp, P. - B., Becker, A., Pühler, A., Reiss, G., & Brückl, H. (2004). Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection. BIOSENSORS & BIOELECTRONICS, 19(10), 1149-1156.
Schotter, J., Kamp, P. - B., Becker, A., Pühler, A., Reiss, G., and Brückl, H. (2004). Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection. BIOSENSORS & BIOELECTRONICS 19, 1149-1156.
Schotter, J., et al., 2004. Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection. BIOSENSORS & BIOELECTRONICS, 19(10), p 1149-1156.
J. Schotter, et al., “Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection”, BIOSENSORS & BIOELECTRONICS, vol. 19, 2004, pp. 1149-1156.
Schotter, J., Kamp, P.-B., Becker, A., Pühler, A., Reiss, G., Brückl, H.: Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection. BIOSENSORS & BIOELECTRONICS. 19, 1149-1156 (2004).
Schotter, J., Kamp, Paul-Bertram, Becker, A., Pühler, Alfred, Reiss, Günter, and Brückl, H. “Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection”. BIOSENSORS & BIOELECTRONICS 19.10 (2004): 1149-1156.
This data publication is cited in the following publications:
This publication cites the following data publications:

37 Citations in Europe PMC

Data provided by Europe PubMed Central.

Giant magnetoresistive-based biosensing probe station system for multiplex protein assays.
Wang Y, Wang W, Yu L, Tu L, Feng Y, Klein T, Wang JP., Biosens Bioelectron 70(), 2015
PMID: 25794959
Simple and portable magnetic immunoassay for rapid detection and sensitive quantification of plant viruses.
Rettcher S, Jungk F, Kuhn C, Krause HJ, Nolke G, Commandeur U, Fischer R, Schillberg S, Schroper F., Appl. Environ. Microbiol. 81(9), 2015
PMID: 25710366
A magnetic nanobead-based bioassay provides sensitive detection of single- and biplex bacterial DNA using a portable AC susceptometer.
Stromberg M, Zardan Gomez de la Torre T, Nilsson M, Svedlindh P, Stromme M., Biotechnol J 9(1), 2014
PMID: 24174315
Lab-on-a-Chip Magneto-Immunoassays: How to Ensure Contact between Superparamagnetic Beads and the Sensor Surface.
Eickenberg B, Meyer J, Helmich L, Kappe D, Auge A, Weddemann A, Wittbracht F, Hutten A., Biosensors (Basel) 3(3), 2013
PMID: 25586262
Microfabricated magnetic structures for future medicine: from sensors to cell actuators.
Vitol EA, Novosad V, Rozhkova EA., Nanomedicine (Lond) 7(10), 2012
PMID: 23148542
Detection of target ssDNA using a microfabricated Hall magnetometer with correlated optical readout.
Hira SM, Aledealat K, Chen KS, Field M, Sullivan GJ, Chase PB, Xiong P, von Molnar S, Strouse GF., J. Biomed. Biotechnol. 2012(), 2012
PMID: 22496610
Magnetic nanoparticles for magnetoresistance-based biodetection.
Sun X, Ho D, Lacroix LM, Xiao JQ, Sun S., IEEE Trans Nanobioscience 11(1), 2012
PMID: 22157074
Magnetic scanometric DNA microarray detection of methyl tertiary butyl ether degrading bacteria for environmental monitoring.
Chan ML, Jaramillo G, Hristova KR, Horsley DA., Biosens Bioelectron 26(5), 2011
PMID: 20889328
Rewritable remote encoding and decoding of miniature multi-bit magnetic tags for high-throughput biological analysis.
Jeong JR, Llandro J, Hong B, Hayward TJ, Mitrelias T, Kopper KP, Trypiniotis T, Steinmuller SJ, Simpson GK, Bland JA., Lab Chip 8(11), 2008
PMID: 18941689

19 References

Data provided by Europe PubMed Central.

Genomagnetic electrochemical assays of DNA hybridization.
Wang J, Xu D, Erdem A, Polsky R, Salazar MA., Talanta 56(5), 2002
PMID: 18968572
The BARC biosensor applied to the detection of biological warfare agents.
Edelstein RL, Tamanaha CR, Sheehan PE, Miller MM, Baselt DR, Whitman LJ, Colton RJ., Biosens Bioelectron 14(10-11), 2000
PMID: 10945455
A DNA array sensor utilizing magnetic microbeads and magnetoelectronic detection
Miller, Journal of Magnetism and Magnetic Materials 225(1-2), 2001
On-chip DNA band detection in microfabricated separation systems
Brahmasandra, 1998
Lab-on-a-Chip: A Revolution in Biological and Medical Sciences.
Figeys, Analytical Chemistry 72(9), 2000
Microfabricated reaction and separation systems.
Krishnan M, Namasivayam V, Lin R, Pal R, Burns MA., Curr. Opin. Biotechnol. 12(1), 2001
PMID: 11167080
A biosensor based on magnetoresistance technology.
Baselt DR, Lee GU, Natesan M, Metzger SW, Sheehan PE, Colton RJ., Biosens Bioelectron 13(7-8), 1998
PMID: 9828367
Monolithic integrated microfluidic DNA amplification and capillary electrophoresis analysis system
Lagally, Sensors and Actuators B Chemical 63(3), 2000
Microparticle detector for biosensor application
Gorschluter, Sensors and Actuators B Chemical 85(1-2), 2002
On-chip manipulation and magnetization assessment of magnetic bead ensembles by integrated spin-valve sensors
Lagae, Journal of Applied Physics 91(10), 2002
Single magnetic microsphere placement and detection on-chip using current line designs with integrated spin valve sensors: Biotechnological applications
Graham, Journal of Applied Physics 91(10), 2002
A miniature integrated device for automated multistep genetic assays.
Anderson RC, Su X, Bogdan GJ, Fenton J., Nucleic Acids Res. 28(12), 2000
PMID: 10871383
From DNA biosensors to gene chips.
Wang J., Nucleic Acids Res. 28(16), 2000
PMID: 10931914
Layered magnetic structures: Evidence for antiferromagnetic coupling of Fe layers across Cr interlayers.
Grunberg P, Schreiber R, Pang Y, Brodsky MB, Sowers H., Phys. Rev. Lett. 57(19), 1986
PMID: 10033726
Giant magnetoresistance of (001)Fe/(001)Cr magnetic superlattices.
Baibich MN, Broto JM, Fert A, Nguyen Van Dau F , Petroff F, Etienne P, Creuzet G, Friederich A, Chazelas J., Phys. Rev. Lett. 61(21), 1988
PMID: 10039127
Large magnetoresistance at room temperature in ferromagnetic thin film tunnel junctions.
Moodera JS, Kinder LR, Wong TM, Meservey R., Phys. Rev. Lett. 74(16), 1995
PMID: 10058155
Model for detection of immobilized superparamagnetic nanosphere assay labels using giant magnetoresistive sensors
Tondra, Journal of Vacuum Science & Technology A Vacuum Surfaces and Films 18(4), 2000
A biochip based on magnetoresistive sensors
Schotter, IEEE Transactions on Magnetics 38(5), 2002

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 15046745
PubMed | Europe PMC

Search this title in

Google Scholar