An improved method for the solution cyclization of peptides under pseudo-high dilution conditions

Malesevic M, Strijowski U, Bachle D, Sewald N (2004)
JOURNAL OF BIOTECHNOLOGY 112(1-2): 73-77.

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Depending on the ring size, the cyclization of peptides often is accompanied by dimerization or cyclodimerization. Hence, these macrocyclizations have to be performed under high dilution conditions. Efficient cyclization of peptides in solution with a minimum amount of solvent succeeds, when a dual syringe pump is used to simultaneously add the linear peptide precursor and a coupling reagent from two separate syringes. (C) 2004 Elsevier B.V. All rights reserved.
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Malesevic M, Strijowski U, Bachle D, Sewald N. An improved method for the solution cyclization of peptides under pseudo-high dilution conditions. JOURNAL OF BIOTECHNOLOGY. 2004;112(1-2):73-77.
Malesevic, M., Strijowski, U., Bachle, D., & Sewald, N. (2004). An improved method for the solution cyclization of peptides under pseudo-high dilution conditions. JOURNAL OF BIOTECHNOLOGY, 112(1-2), 73-77. doi:10.1016/j.jbiotec.2004.03.015
Malesevic, M., Strijowski, U., Bachle, D., and Sewald, N. (2004). An improved method for the solution cyclization of peptides under pseudo-high dilution conditions. JOURNAL OF BIOTECHNOLOGY 112, 73-77.
Malesevic, M., et al., 2004. An improved method for the solution cyclization of peptides under pseudo-high dilution conditions. JOURNAL OF BIOTECHNOLOGY, 112(1-2), p 73-77.
M. Malesevic, et al., “An improved method for the solution cyclization of peptides under pseudo-high dilution conditions”, JOURNAL OF BIOTECHNOLOGY, vol. 112, 2004, pp. 73-77.
Malesevic, M., Strijowski, U., Bachle, D., Sewald, N.: An improved method for the solution cyclization of peptides under pseudo-high dilution conditions. JOURNAL OF BIOTECHNOLOGY. 112, 73-77 (2004).
Malesevic, M, Strijowski, U, Bachle, D, and Sewald, Norbert. “An improved method for the solution cyclization of peptides under pseudo-high dilution conditions”. JOURNAL OF BIOTECHNOLOGY 112.1-2 (2004): 73-77.
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