Adaptation of Corynebacterium glutamicum to ammonium limitation: A global analysis using transcriptome and proteome techniques

Silberbach M, Schafer M, Hüser AT, Kalinowski J, Pühler A, Kramer R, Burkovski A (2005)
APPLIED AND ENVIRONMENTAL MICROBIOLOGY 71(5): 2391-2402.

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The response of Corynebacterium glutamicum to ammonium limitation was studied by transcriptional and proteome profiling of cells grown in a chemostat. Our results show that ammonium-limited growth of C. glutamicum results in a rearrangement of the cellular transport capacity, changes in metabolic pathways for nitrogen assimilation, amino acid biosynthesis, and carbon metabolism, as well as a decreased cell division. Since transcription at different growth rates was studied, it was possible to distinguish specific responses to ammonium limitation and more general, growth rate-dependent alterations in gene expression. The latter include a number of genes encoding ribosomal proteins and genes for F0F1-ATP synthase subunits.
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Silberbach M, Schafer M, Hüser AT, et al. Adaptation of Corynebacterium glutamicum to ammonium limitation: A global analysis using transcriptome and proteome techniques. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2005;71(5):2391-2402.
Silberbach, M., Schafer, M., Hüser, A. T., Kalinowski, J., Pühler, A., Kramer, R., & Burkovski, A. (2005). Adaptation of Corynebacterium glutamicum to ammonium limitation: A global analysis using transcriptome and proteome techniques. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 71(5), 2391-2402. doi:10.1128/AEM.71.5.2391-2402.2005
Silberbach, M., Schafer, M., Hüser, A. T., Kalinowski, J., Pühler, A., Kramer, R., and Burkovski, A. (2005). Adaptation of Corynebacterium glutamicum to ammonium limitation: A global analysis using transcriptome and proteome techniques. APPLIED AND ENVIRONMENTAL MICROBIOLOGY 71, 2391-2402.
Silberbach, M., et al., 2005. Adaptation of Corynebacterium glutamicum to ammonium limitation: A global analysis using transcriptome and proteome techniques. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 71(5), p 2391-2402.
M. Silberbach, et al., “Adaptation of Corynebacterium glutamicum to ammonium limitation: A global analysis using transcriptome and proteome techniques”, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 71, 2005, pp. 2391-2402.
Silberbach, M., Schafer, M., Hüser, A.T., Kalinowski, J., Pühler, A., Kramer, R., Burkovski, A.: Adaptation of Corynebacterium glutamicum to ammonium limitation: A global analysis using transcriptome and proteome techniques. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 71, 2391-2402 (2005).
Silberbach, M., Schafer, M., Hüser, Andrea T., Kalinowski, Jörn, Pühler, Alfred, Kramer, R., and Burkovski, A. “Adaptation of Corynebacterium glutamicum to ammonium limitation: A global analysis using transcriptome and proteome techniques”. APPLIED AND ENVIRONMENTAL MICROBIOLOGY 71.5 (2005): 2391-2402.
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36 References

Data provided by Europe PubMed Central.

Sensing nitrogen limitation in Corynebacterium glutamicum: the role of glnK and glnD.
Nolden L, Ngouoto-Nkili CE, Bendt AK, Kramer R, Burkovski A., Mol. Microbiol. 42(5), 2001
PMID: 11886559

AUTHOR UNKNOWN, 1989

AUTHOR UNKNOWN, 1973
Response to nitrogen starvation in Corynebacterium glutamicum.
Schmi R, Uhlemann EM, Nolden L, Wersch G, Hecker R, Hermann T, Marx A, Burkovski A., FEMS Microbiol. Lett. 187(1), 2000
PMID: 10828405
A functionally split pathway for lysine synthesis in Corynebacterium glutamicium.
Schrumpf B, Schwarzer A, Kalinowski J, Puhler A, Eggeling L, Sahm H., J. Bacteriol. 173(14), 1991
PMID: 1906065

AUTHOR UNKNOWN, 2002

AUTHOR UNKNOWN, 1960
Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression in Bacillus subtilis.
Yoshida K, Kobayashi K, Miwa Y, Kang CM, Matsunaga M, Yamaguchi H, Tojo S, Yamamoto M, Nishi R, Ogasawara N, Nakayama T, Fujita Y., Nucleic Acids Res. 29(3), 2001
PMID: 11160890
Nitrogen regulatory protein C-controlled genes of Escherichia coli: scavenging as a defense against nitrogen limitation.
Zimmer DP, Soupene E, Lee HL, Wendisch VF, Khodursky AB, Peter BJ, Bender RA, Kustu S., Proc. Natl. Acad. Sci. U.S.A. 97(26), 2000
PMID: 11121068

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