High magnitude of light retardation by the zona pellucida is associated with conception cycles

Shen Y, Stalf T, Mehnert C, Eichenlaub-Ritter U, Tinneberg HR (2005)
HUMAN REPRODUCTION 20(6): 1596-1606.

Download
No fulltext has been uploaded. References only!
Journal Article | Original Article | Published | English

No fulltext has been uploaded

Author
; ; ; ;
Abstract
BACKGROUND: Failures in expression of zona proteins correlate to subfertility in animals. Low expression of the zona proteins by the growing human oocyte may indicate reduced developmental potential. Therefore, we non-invasively analysed the thickness and the structure of the zona pellucida (ZP) of human oocytes with respect to embryo fate after ICSI. METHODS: Retardance magnitude and thickness of the inner, middle and outer layers of the ZP were quantitatively analysed by a Polscope in 166 oocytes selected for transfer after ICSI (63 patients; 32.8 +/- 4.4 years) on the basis of pronuclear score at day 1. Blastomere number was determined at day 2. Data were compared between conception cycles (CC; 65 oocytes/23 patients) and non-conception cycles (NCC; 101 oocytes/40 patients) and with respect to maternal age. RESULTS: The thickness was slightly elevated (P < 0.001), and the mean magnitude of light retardance was nearly 30% higher (P < 0.001) in the inner layer of the zona pellucida of oocytes contributing to CC compared to NCC. Embryos in the CC group tended to develop faster. CONCLUSIONS: The magnitude of light retardance by the zona pellucida inner layer appears to present a unique non-invasive marker for oocyte developmental potential.
Publishing Year
ISSN
eISSN
PUB-ID

Cite this

Shen Y, Stalf T, Mehnert C, Eichenlaub-Ritter U, Tinneberg HR. High magnitude of light retardation by the zona pellucida is associated with conception cycles. HUMAN REPRODUCTION. 2005;20(6):1596-1606.
Shen, Y., Stalf, T., Mehnert, C., Eichenlaub-Ritter, U., & Tinneberg, H. R. (2005). High magnitude of light retardation by the zona pellucida is associated with conception cycles. HUMAN REPRODUCTION, 20(6), 1596-1606. doi:10.1093/humrep/deh811
Shen, Y., Stalf, T., Mehnert, C., Eichenlaub-Ritter, U., and Tinneberg, H. R. (2005). High magnitude of light retardation by the zona pellucida is associated with conception cycles. HUMAN REPRODUCTION 20, 1596-1606.
Shen, Y., et al., 2005. High magnitude of light retardation by the zona pellucida is associated with conception cycles. HUMAN REPRODUCTION, 20(6), p 1596-1606.
Y. Shen, et al., “High magnitude of light retardation by the zona pellucida is associated with conception cycles”, HUMAN REPRODUCTION, vol. 20, 2005, pp. 1596-1606.
Shen, Y., Stalf, T., Mehnert, C., Eichenlaub-Ritter, U., Tinneberg, H.R.: High magnitude of light retardation by the zona pellucida is associated with conception cycles. HUMAN REPRODUCTION. 20, 1596-1606 (2005).
Shen, Y, Stalf, T, Mehnert, C, Eichenlaub-Ritter, Ursula, and Tinneberg, HR. “High magnitude of light retardation by the zona pellucida is associated with conception cycles”. HUMAN REPRODUCTION 20.6 (2005): 1596-1606.
This data publication is cited in the following publications:
This publication cites the following data publications:

42 Citations in Europe PMC

Data provided by Europe PubMed Central.

Oocyte polarized light microscopy, assay of specific follicular fluid metabolites, and gene expression in cumulus cells as different approaches to predict fertilization efficiency after ICSI.
Revelli A, Canosa S, Bergandi L, Skorokhod OA, Biasoni V, Carosso A, Bertagna A, Maule M, Aldieri E, D'Eufemia MD, Evangelista F, Colacurci N, Benedetto C., Reprod. Biol. Endocrinol. 15(1), 2017
PMID: 28645283
Novel zona pellucida gene variants identified in patients with oocyte anomalies.
Yang P, Luan X, Peng Y, Chen T, Su S, Zhang C, Wang Z, Cheng L, Zhang X, Wang Y, Chen ZJ, Zhao H., Fertil. Steril. 107(6), 2017
PMID: 28577617
Developmental potential of embryos from cycles containing oocytes with severe ovoid zona pellucida.
Xiong S, Han W, Liu W, Wu L, Liu JX, Gao Y, Huang G., Hum Fertil (Camb) (), 2017
PMID: 28545306
Noninvasive imaging systems for gametes and embryo selection in IVF programs: a review.
Omidi M, Faramarzi A, Agharahimi A, Khalili MA., J Microsc 267(3), 2017
PMID: 28470749
Evaluation of equine oocyte developmental competence using polarized light microscopy.
Bertero A, Ritrovato F, Evangelista F, Stabile V, Fortina R, Ricci A, Revelli A, Vincenti L, Nervo T., Reproduction 153(6), 2017
PMID: 28283673
Zona pellucida gene mRNA expression in human oocytes is related to oocyte maturity, zona inner layer retardance and fertilization competence.
Canosa S, Adriaenssens T, Coucke W, Dalmasso P, Revelli A, Benedetto C, Smitz J., Mol. Hum. Reprod. 23(5), 2017
PMID: 28204536
Fertilization and embryo quality of mature oocytes with specific morphological abnormalities.
Yu EJ, Ahn H, Lee JM, Jee BC, Kim SH., Clin Exp Reprod Med 42(4), 2015
PMID: 26815385
Are zona pellucida genes involved in recurrent oocyte lysis observed during in vitro fertilization?
Ferre M, Amati-Bonneau P, Moriniere C, Ferre-L'Hotellier V, Lemerle S, Przyrowski D, Procaccio V, Descamps P, Reynier P, May-Panloup P., J. Assist. Reprod. Genet. 31(2), 2014
PMID: 24242990
Oocyte morphology on day 0 correlates with aneuploidy as detected by polar body biopsy and FISH.
Schmutzler AG, Acar-Perk B, Weimer J, Salmassi A, Sievers K, Tobler M, Mettler L, Jonat W, Arnold N., Arch. Gynecol. Obstet. 289(2), 2014
PMID: 23880887
Quantitative polarized light microscopy of unstained mammalian cochlear sections.
Kalwani NM, Ong CA, Lysaght AC, Haward SJ, McKinley GH, Stankovic KM., J Biomed Opt 18(2), 2013
PMID: 23407909
Evaluation of zona pellucida birefringence intensity during in vitro maturation of oocytes from stimulated cycles.
Petersen CG, Vagnini LD, Mauri AL, Massaro FC, Silva LF, Cavagna M, Baruffi RL, Oliveira JB, Franco JG Jr., Reprod. Biol. Endocrinol. 9(), 2011
PMID: 21513548
Slow-freezing-induced changes of birefringent structures in human oocytes are related to responsiveness to ovulation induction.
Molinari E, Revelli A, Racca C, Delle Piane L, Massobrio M., Reprod. Biomed. Online 20(5), 2010
PMID: 20219427
Phase-subtraction cell-counting method for live mouse embryos beyond the eight-cell stage.
Warger WC 2nd, Newmark JA, Warner CM, DiMarzio CA., J Biomed Opt 13(3), 2008
PMID: 18601550

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 15734754
PubMed | Europe PMC

Search this title in

Google Scholar