Methadone treatment of injecting opioid users for prevention of HIV infection

Gowing LR, Farrell M, Bornemann R, Sullivan LE, Ali RL (2006)
JOURNAL OF GENERAL INTERNAL MEDICINE 21(2): 193-195.

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Abstract
OBJECTIVE: To assess the effects of oral substitution treatment for opioid-dependent injecting drug users on HIV risk behaviors and infections. DATA SOURCES: Multiple electronic databases were searched. Reference lists of retrieved articles were checked. METHODS: Because of varying methodologies of available studies, this systematic review was limited to a descriptive summary, looking at consistency of outcomes across studies. RESULTS: Twenty-eight studies involving methadone treatment were included in the review. Methadone maintenance treatment is associated with statistically significant reductions in injecting use and sharing of injecting equipment. It is also associated with reductions in numbers of injecting drug users reporting multiple sex partners or exchanges of sex for drugs or money, but has little effect on condom use. It appears that the reductions in risk behaviors do translate into fewer cases of HIV infection. CONCLUSIONS: Methadone maintenance treatment for injecting drug users significantly reduces the risk of transmission of HIV and should be provided as a component of a strategic approach to the prevention and control of HIV infection. There is insufficient evidence to determine whether other forms of oral substitution treatment also reduce the risk of HIV transmission.
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Gowing LR, Farrell M, Bornemann R, Sullivan LE, Ali RL. Methadone treatment of injecting opioid users for prevention of HIV infection. JOURNAL OF GENERAL INTERNAL MEDICINE. 2006;21(2):193-195.
Gowing, L. R., Farrell, M., Bornemann, R., Sullivan, L. E., & Ali, R. L. (2006). Methadone treatment of injecting opioid users for prevention of HIV infection. JOURNAL OF GENERAL INTERNAL MEDICINE, 21(2), 193-195.
Gowing, L. R., Farrell, M., Bornemann, R., Sullivan, L. E., and Ali, R. L. (2006). Methadone treatment of injecting opioid users for prevention of HIV infection. JOURNAL OF GENERAL INTERNAL MEDICINE 21, 193-195.
Gowing, L.R., et al., 2006. Methadone treatment of injecting opioid users for prevention of HIV infection. JOURNAL OF GENERAL INTERNAL MEDICINE, 21(2), p 193-195.
L.R. Gowing, et al., “Methadone treatment of injecting opioid users for prevention of HIV infection”, JOURNAL OF GENERAL INTERNAL MEDICINE, vol. 21, 2006, pp. 193-195.
Gowing, L.R., Farrell, M., Bornemann, R., Sullivan, L.E., Ali, R.L.: Methadone treatment of injecting opioid users for prevention of HIV infection. JOURNAL OF GENERAL INTERNAL MEDICINE. 21, 193-195 (2006).
Gowing, LR, Farrell, M, Bornemann, Reinhard, Sullivan, LE, and Ali, RL. “Methadone treatment of injecting opioid users for prevention of HIV infection”. JOURNAL OF GENERAL INTERNAL MEDICINE 21.2 (2006): 193-195.
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Metzger DS, Donnell D, Celentano DD, Jackson JB, Shao Y, Aramrattana A, Wei L, Fu L, Ma J, Lucas GM, Chawarski M, Ruan Y, Richardson P, Shin K, Chen RY, Sugarman J, Dye BJ, Rose SM, Beauchamp G, Burns DN; HPTN 058 Protocol Team., J. Acquir. Immune Defic. Syndr. 68(5), 2015
PMID: 25564105
The cost of providing methadone maintenance treatment in Ontario, Canada.
Zaric GS, Brennan AW, Varenbut M, Daiter JM., Am J Drug Alcohol Abuse 38(6), 2012
PMID: 22783917
HIV risks and seroprevalence among Mexican American injection drug users in California.
Martinez AN, Bluthenthal RN, Flynn NM, Anderson RL, Kral AH., AIDS Behav 15(1), 2011
PMID: 20020194

29 References

Data provided by Europe PubMed Central.

Methadone treatment as a determinant of HIV risk reduction among injecting drug users: a nested case-control study.
Serpelloni G, Carrieri MP, Rezza G, Morganti S, Gomma M, Binkin N., AIDS Care 6(2), 1994
PMID: 8061081
Buprenorphine treatment for opioid dependence: the relative efficacy of daily, twice and thrice weekly dosing.
Marsch LA, Bickel WK, Badger GJ, Jacobs EA., Drug Alcohol Depend 77(2), 2005
PMID: 15664721
Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence
Mattick RP, Breen C, Kimber J, Davoli M., 2002
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence.
Mattick RP, Kimber J, Breen C, Davoli M., Cochrane Database Syst Rev (2), 2003
PMID: 12804429

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