Microbial transformation of the steroidal alkaloid dictyophlebine by Rhizopus stolonifer

Devkota KP, Choudhary MI, Nawaz SA, Lannang AM, Lenta BN, Fokou PA, Sewald N (2007)
Chemical & Pharmaceutical Bulletin 55(4): 682-684.

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Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Abstract / Bemerkung
The microbial transformation of a steroidal alkaloid, dictyophlebine (1) with Rhizopus stolonifer (ATCC 10404) afforded three oxidized metabolites 2-4. Compound 2 was found to be a new product. These metabolites were structurally characterized on the basis of modern spectroscopic techniques. Their inhibitory activity towards acetyl- and butyrylcholinesterase has been evaluated and the new product 2 has been found to be more potent than the parent compound and other metabolites.
Erscheinungsjahr
Zeitschriftentitel
Chemical & Pharmaceutical Bulletin
Band
55
Ausgabe
4
Seite(n)
682-684
ISSN
eISSN
PUB-ID

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Devkota KP, Choudhary MI, Nawaz SA, et al. Microbial transformation of the steroidal alkaloid dictyophlebine by Rhizopus stolonifer. Chemical & Pharmaceutical Bulletin. 2007;55(4):682-684.
Devkota, K. P., Choudhary, M. I., Nawaz, S. A., Lannang, A. M., Lenta, B. N., Fokou, P. A., & Sewald, N. (2007). Microbial transformation of the steroidal alkaloid dictyophlebine by Rhizopus stolonifer. Chemical & Pharmaceutical Bulletin, 55(4), 682-684. doi:10.1248/cpb.55.682
Devkota, K. P., Choudhary, M. I., Nawaz, S. A., Lannang, A. M., Lenta, B. N., Fokou, P. A., and Sewald, N. (2007). Microbial transformation of the steroidal alkaloid dictyophlebine by Rhizopus stolonifer. Chemical & Pharmaceutical Bulletin 55, 682-684.
Devkota, K.P., et al., 2007. Microbial transformation of the steroidal alkaloid dictyophlebine by Rhizopus stolonifer. Chemical & Pharmaceutical Bulletin, 55(4), p 682-684.
K.P. Devkota, et al., “Microbial transformation of the steroidal alkaloid dictyophlebine by Rhizopus stolonifer”, Chemical & Pharmaceutical Bulletin, vol. 55, 2007, pp. 682-684.
Devkota, K.P., Choudhary, M.I., Nawaz, S.A., Lannang, A.M., Lenta, B.N., Fokou, P.A., Sewald, N.: Microbial transformation of the steroidal alkaloid dictyophlebine by Rhizopus stolonifer. Chemical & Pharmaceutical Bulletin. 55, 682-684 (2007).
Devkota, Krishna Prasad, Choudhary, Muhammad Iqbal, Nawaz, Sarfaraz Ahmed, Lannang, Alain Meli, Lenta, Bruno Ndjakou, Fokou, Patrice Aime, and Sewald, Norbert. “Microbial transformation of the steroidal alkaloid dictyophlebine by Rhizopus stolonifer”. Chemical & Pharmaceutical Bulletin 55.4 (2007): 682-684.

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