Interferon-beta modulates protein synthesis in the central nervous system

Beyer S, Raether G, Stadler K, Hoffrogge R, Scharf C, Rolfs A, Mix E, Strauss U (2009)
JOURNAL OF NEUROIMMUNOLOGY 213(1-2): 31-38.

Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Autor
; ; ; ; ; ; ;
Abstract / Bemerkung
Interferon-beta (IFN-beta), acting canonically via the modulation of transcription, affects neocortical pyramidal neurons. By use of 2-D differential gel electrophoresis and subsequent mass spectrometry we identified IFN-beta regulated proteins in the central nervous system. These proteins are involved in cytoskeleton assembly, protein transport and nucleotide metabolism and, as such, serve regenerative and protective functions. Electrophysiologically, IFN-beta mediated protein synthesis is essential for part of the excitatory neuronal effects, as revealed under blockade of protein biosynthesis. This study presents novel effects of IFN-beta in the central nervous system and begins to unravel the mechanism behind the known excitability changes in neurons. (C) 2009 Elsevier B.V. All rights reserved.
Erscheinungsjahr
Zeitschriftentitel
JOURNAL OF NEUROIMMUNOLOGY
Band
213
Zeitschriftennummer
1-2
Seite
31-38
ISSN
PUB-ID

Zitieren

Beyer S, Raether G, Stadler K, et al. Interferon-beta modulates protein synthesis in the central nervous system. JOURNAL OF NEUROIMMUNOLOGY. 2009;213(1-2):31-38.
Beyer, S., Raether, G., Stadler, K., Hoffrogge, R., Scharf, C., Rolfs, A., Mix, E., et al. (2009). Interferon-beta modulates protein synthesis in the central nervous system. JOURNAL OF NEUROIMMUNOLOGY, 213(1-2), 31-38. doi:10.1016/j.jneuroim.2009.06.004
Beyer, S., Raether, G., Stadler, K., Hoffrogge, R., Scharf, C., Rolfs, A., Mix, E., and Strauss, U. (2009). Interferon-beta modulates protein synthesis in the central nervous system. JOURNAL OF NEUROIMMUNOLOGY 213, 31-38.
Beyer, S., et al., 2009. Interferon-beta modulates protein synthesis in the central nervous system. JOURNAL OF NEUROIMMUNOLOGY, 213(1-2), p 31-38.
S. Beyer, et al., “Interferon-beta modulates protein synthesis in the central nervous system”, JOURNAL OF NEUROIMMUNOLOGY, vol. 213, 2009, pp. 31-38.
Beyer, S., Raether, G., Stadler, K., Hoffrogge, R., Scharf, C., Rolfs, A., Mix, E., Strauss, U.: Interferon-beta modulates protein synthesis in the central nervous system. JOURNAL OF NEUROIMMUNOLOGY. 213, 31-38 (2009).
Beyer, Susanne, Raether, Gergana, Stadler, Konstantin, Hoffrogge, Raimund, Scharf, Christian, Rolfs, Arndt, Mix, Eilhard, and Strauss, Ulf. “Interferon-beta modulates protein synthesis in the central nervous system”. JOURNAL OF NEUROIMMUNOLOGY 213.1-2 (2009): 31-38.

4 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Toll-like receptor 3 deficiency decreases epileptogenesis in a pilocarpine model of SE-induced epilepsy in mice.
Gross A, Benninger F, Madar R, Illouz T, Griffioen K, Steiner I, Offen D, Okun E., Epilepsia 58(4), 2017
PMID: 28166388
Elevation in type I interferons inhibits HCN1 and slows cortical neuronal oscillations.
Stadler K, Bierwirth C, Stoenica L, Battefeld A, Reetz O, Mix E, Schuchmann S, Velmans T, Rosenberger K, Bräuer AU, Lehnardt S, Nitsch R, Budt M, Wolff T, Kole MH, Strauss U., Cereb Cortex 24(1), 2014
PMID: 23042740

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 19541371
PubMed | Europe PMC

Suchen in

Google Scholar