Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children

Kalbe E, Brand M, Thiel A, Kessler J, Markowitsch HJ (2008)
NEUROCASE 14(1): 15-28.

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Abstract
We report a case of a delusional patient who had killed two of her children in an attempted 'extended suicide'. She was convinced of a genetic defect that caused autobiographical memory and emotional deficits and made life 'senseless'. Neuropsychological tests revealed dysfunctions in remembering emotional details of personal episodes and theory of mind. Water positron emission tomography (O-15) with a paradigm used in a former study by Fink et al. (1996) with healthy controls elicited abnormal activations during autobiographical memory retrieval characterised by a lack of prefrontal and limbic activity. We conclude that these imaging findings reflect neural correlates of the self-reported and objectified autobiographical dysfunctions. Furthermore, they indicate that beliefs or prejudices may have a major impact on the brain's processing of the personal past.
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Kalbe E, Brand M, Thiel A, Kessler J, Markowitsch HJ. Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children. NEUROCASE. 2008;14(1):15-28.
Kalbe, E., Brand, M., Thiel, A., Kessler, J., & Markowitsch, H. J. (2008). Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children. NEUROCASE, 14(1), 15-28.
Kalbe, E., Brand, M., Thiel, A., Kessler, J., and Markowitsch, H. J. (2008). Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children. NEUROCASE 14, 15-28.
Kalbe, E., et al., 2008. Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children. NEUROCASE, 14(1), p 15-28.
E. Kalbe, et al., “Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children”, NEUROCASE, vol. 14, 2008, pp. 15-28.
Kalbe, E., Brand, M., Thiel, A., Kessler, J., Markowitsch, H.J.: Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children. NEUROCASE. 14, 15-28 (2008).
Kalbe, E., Brand, M., Thiel, A., Kessler, J., and Markowitsch, Hans J. “Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children”. NEUROCASE 14.1 (2008): 15-28.
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PMID: 21283572

114 References

Data provided by Europe PubMed Central.

The functional neuroanatomy of autobiographical memory: a meta-analysis.
Svoboda E, McKinnon MC, Levine B., Neuropsychologia 44(12), 2006
PMID: 16806314
Plasticity of language networks in patients with brain tumors: a positron emission tomography activation study.
Thiel A, Herholz K, Koyuncu A, Ghaemi M, Kracht LW, Habedank B, Heiss WD., Ann. Neurol. 50(5), 2001
PMID: 11706968
Episodic memory: from mind to brain.
Tulving E., Annu Rev Psychol 53(), 2002
PMID: 11752477

Tulving, 2005
Self-face recognition activates a frontoparietal "mirror" network in the right hemisphere: an event-related fMRI study.
Uddin LQ, Kaplan JT, Molnar-Szakacs I, Zaidel E, Iacoboni M., Neuroimage 25(3), 2005
PMID: 15808992
Bi-hemispheric engagement in the retrieval of autobiographical episodes.
Vandekerckhove MM, Markowitsch HJ, Mertens M, Woermann FG., Behav Neurol 16(4), 2005
PMID: 16518010

Viard, Cerebral Cortex (), 2007
Neural correlates of first-person perspective as one constituent of human self-consciousness.
Vogeley K, May M, Ritzl A, Falkai P, Zilles K, Fink GR., J Cogn Neurosci 16(5), 2004
PMID: 15200709
The possible contribution of the septal region to memory.
von Cramon DY, Markowitsch HJ, Schuri U., Neuropsychologia 31(11), 1993
PMID: 8107978

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