Helicobacter pylori-infection status and childhood living conditions are associated with signs of allergic diseases in an occupational population

Pfefferle PI, Krämer A (2008)
EUROPEAN JOURNAL OF EPIDEMIOLOGY 23(9): 635-640.

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This study assessed the hypothesis that Helicobacter pylori infection and specific living conditions in childhood are associated with allergic outcomes. A cross-sectional survey containing retrospective questions concerning childhood was performed in an occupational population in 2001. This survey included self-administered questionnaire data and stool tests. An inverse association between positive H. pylori infection status and physician diagnosis of allergy/12 month period of anti-allergic medication was observed in a logistic regression model, adjusted for potential confounders (age, sex, nationality, smoking status and education of the participant) (OR 0.26, 95% CI: 0.08-0.84). In addition, childhood living conditions were associated with H. pylori infection status and signs of allergies. In line with the "hygiene hypothesis" our model supports an inverse association between early childhood infection with H. pylori and allergic disease in adulthood.
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Pfefferle PI, Krämer A. Helicobacter pylori-infection status and childhood living conditions are associated with signs of allergic diseases in an occupational population. EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2008;23(9):635-640.
Pfefferle, P. I., & Krämer, A. (2008). Helicobacter pylori-infection status and childhood living conditions are associated with signs of allergic diseases in an occupational population. EUROPEAN JOURNAL OF EPIDEMIOLOGY, 23(9), 635-640.
Pfefferle, P. I., and Krämer, A. (2008). Helicobacter pylori-infection status and childhood living conditions are associated with signs of allergic diseases in an occupational population. EUROPEAN JOURNAL OF EPIDEMIOLOGY 23, 635-640.
Pfefferle, P.I., & Krämer, A., 2008. Helicobacter pylori-infection status and childhood living conditions are associated with signs of allergic diseases in an occupational population. EUROPEAN JOURNAL OF EPIDEMIOLOGY, 23(9), p 635-640.
P.I. Pfefferle and A. Krämer, “Helicobacter pylori-infection status and childhood living conditions are associated with signs of allergic diseases in an occupational population”, EUROPEAN JOURNAL OF EPIDEMIOLOGY, vol. 23, 2008, pp. 635-640.
Pfefferle, P.I., Krämer, A.: Helicobacter pylori-infection status and childhood living conditions are associated with signs of allergic diseases in an occupational population. EUROPEAN JOURNAL OF EPIDEMIOLOGY. 23, 635-640 (2008).
Pfefferle, Petra Ina, and Krämer, Alexander. “Helicobacter pylori-infection status and childhood living conditions are associated with signs of allergic diseases in an occupational population”. EUROPEAN JOURNAL OF EPIDEMIOLOGY 23.9 (2008): 635-640.
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