Confabulations in alcoholic Korsakoff patients

Borsutzky S, Fujiwara E, Brand M, Markowitsch HJ (2008)
NEUROPSYCHOLOGIA 46(13): 3133-3143.

Journal Article | Published | English

No fulltext has been uploaded

Abstract
Besides forgetting, memory is also prone to distortions, errors and illusions. Confabulation is one type of memory distortion that may occur in cases of brain damage. Although confabulations are described anecdotally in patients with alcoholic Korsakoff syndrome (KS), there are few systematic investigations of the presence and nature of these types of false memories in KS. Moreover, it is unclear whether KS patients' confabulations evenly affect all types of memories, or whether certain memory domains are more susceptible. Our study attempted to clarify two questions: first, whether confabulations are a critical feature of the cognitive impairment associated with long-term KS in a large sample of patients (N=42). Second, we investigated which memory domain is most likely affected by confabulations in KS. To elicit confabulations, we used a Confabulation Interview containing questions from different memory domains. We found that KS patients overall confabulated more compared to a group of healthy subjects. Furthermore, we found that patients confabulated most within the episodic/autobiographical memory domain. Our results imply that besides pronounced memory deficits typically associated with KS, confabulation can also be regarded as a clinical feature of the disease. The preponderance of episodic confabulation obtained here by using a standardized test, confirms anecdotic reports that KS patients confabulate in everyday life mainly with respect to their personal past and present. Thus, for a detailed description of the memory profile of KS patients, the screening of confabulation tendencies may be a useful supplementary clinical tool.
Publishing Year
ISSN
PUB-ID

Cite this

Borsutzky S, Fujiwara E, Brand M, Markowitsch HJ. Confabulations in alcoholic Korsakoff patients. NEUROPSYCHOLOGIA. 2008;46(13):3133-3143.
Borsutzky, S., Fujiwara, E., Brand, M., & Markowitsch, H. J. (2008). Confabulations in alcoholic Korsakoff patients. NEUROPSYCHOLOGIA, 46(13), 3133-3143.
Borsutzky, S., Fujiwara, E., Brand, M., and Markowitsch, H. J. (2008). Confabulations in alcoholic Korsakoff patients. NEUROPSYCHOLOGIA 46, 3133-3143.
Borsutzky, S., et al., 2008. Confabulations in alcoholic Korsakoff patients. NEUROPSYCHOLOGIA, 46(13), p 3133-3143.
S. Borsutzky, et al., “Confabulations in alcoholic Korsakoff patients”, NEUROPSYCHOLOGIA, vol. 46, 2008, pp. 3133-3143.
Borsutzky, S., Fujiwara, E., Brand, M., Markowitsch, H.J.: Confabulations in alcoholic Korsakoff patients. NEUROPSYCHOLOGIA. 46, 3133-3143 (2008).
Borsutzky, Sabine, Fujiwara, Esther, Brand, Matthias, and Markowitsch, Hans J. “Confabulations in alcoholic Korsakoff patients”. NEUROPSYCHOLOGIA 46.13 (2008): 3133-3143.
This data publication is cited in the following publications:
This publication cites the following data publications:

14 Citations in Europe PMC

Data provided by Europe PubMed Central.

Revisiting the continuum hypothesis: toward an in-depth exploration of executive functions in korsakoff syndrome.
Brion M, Pitel AL, Beaunieux H, Maurage P., Front Hum Neurosci 8(), 2014
PMID: 25071526
Memory and self-neuroscientific landscapes.
Markowitsch HJ., ISRN Neurosci 2013(), 2013
PMID: 24967303
Social cognition in a case of amnesia with neurodevelopmental mechanisms.
Staniloiu A, Borsutzky S, Woermann FG, Markowitsch HJ., Front Psychol 4(), 2013
PMID: 23805111
Flashbulb memories in patients with temporal lobe epilepsy.
Metternich B, Wagner K, Schulze-Bonhage A, Buschmann F, McCarthy RA., Epilepsy Behav 28(1), 2013
PMID: 23665641
Isolated prospective confabulation in Wernicke-Korsakoff syndrome: a case for reality filtering.
Schnider A, Nahum L, Pignat JM, Leemann B, Lovblad KO, Wissmeyer M, Ptak R., Neurocase 19(1), 2013
PMID: 22512690
Anterograde episodic memory in Korsakoff syndrome.
Fama R, Pitel AL, Sullivan EV., Neuropsychol Rev 22(2), 2012
PMID: 22644546
Remote memory function and dysfunction in Korsakoff's syndrome.
Race E, Verfaellie M., Neuropsychol Rev 22(2), 2012
PMID: 22528863
Amnesic disorders.
Markowitsch HJ, Staniloiu A., Lancet 380(9851), 2012
PMID: 22503117
Susceptibility to false memories in patients with ACoA aneurysm.
Borsutzky S, Fujiwara E, Brand M, Markowitsch HJ., Neuropsychologia 48(10), 2010
PMID: 20488196
Confabulation versus experimentally induced false memories in Korsakoff patients.
Van Damme I, d'Ydewalle G., J Neuropsychol 4(Pt 2), 2010
PMID: 19930792
[Sergei Sergeyevich Korsakov (1854-1900): the scholar, the thinker, the psychiatrist, the humanist].
Witkowski T, Pitel AL, Beaunieux H, Viader F, Desgranges B, Eustache F., Rev. Neurol. (Paris) 164(12 Suppl), 2008
PMID: 19268191

95 References

Data provided by Europe PubMed Central.

Spontaneous confabulation, reality monitoring, and the limbic system--a review.
Schnider A., Brain Res. Brain Res. Rev. 36(2-3), 2001
PMID: 11690611
Spontaneous confabulation and the adaptation of thought to ongoing reality
Schnider, Nature Review Neuroscience 4(), 2003
Recovery from spontaneous confabulations parallels recovery of temporal confusion in memory.
Schnider A, Ptak R, von Daniken C, Remonda L., Neurology 55(1), 2000
PMID: 10891909
Disorientation in amnesia. A confusion of memory traces.
Schnider A, von Daniken C, Gutbrod K., Brain 119 ( Pt 5)(), 1996
PMID: 8931585
The mechanisms of spontaneous and provoked confabulations.
Schnider A, von Daniken C, Gutbrod K., Brain 119 ( Pt 4)(), 1996
PMID: 8813298
The ability of amnesic subjects to estimate time intervals.
Shaw C, Aggleton JP., Neuropsychologia 32(7), 1994
PMID: 7936168
Impaired processing of affective prosody in Korsakoff's syndrome.
Snitz BE, Hellinger A, Daum I., Cortex 38(5), 2002
PMID: 12507048

Spreen, 1998
Studies of interference in serial verbal reaction
Stroop, Journal of Experimental Psychology 18(), 1935
Hippocampal volume deficits in alcoholic Korsakoff's syndrome.
Sullivan EV, Marsh L., Neurology 61(12), 2003
PMID: 14694035

Talland, 1965
Confabulation and memory in patients with Alzheimer's disease.
Tallberg IM, Almkvist O., J Clin Exp Neuropsychol 23(2), 2001
PMID: 11309671

Tewes, 1991
The natural history and pathophysiology of Wernicke's encephalopathy and Korsakoff's psychosis
Thomson, Alcohol & Alcoholism 41(), 2006
Confabulation: damage to a specific inferior medial prefrontal system.
Turner MS, Cipolotti L, Yousry TA, Shallice T., Cortex 44(6), 2008
PMID: 18472034
Über die Psychologie des Korsakowsyndroms
Van, Monatszeitschrift für Psychiatrie und Neurologie (), 1932

Victor, 1989
"Wineglass" confabulations among brain-damaged alcoholics on the Wechsler Memory Scale-Revised visual reproduction subtest.
Welch LW, Nimmerrichter A, Gilliland R, King DE, Martin PR., Cortex 33(3), 1997
PMID: 9339334

AUTHOR UNKNOWN, 0

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 18675286
PubMed | Europe PMC

Search this title in

Google Scholar