233 Publikationen
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2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2986983Blöbaum L, Torello Pianale L, Olsson L, Grünberger A (2024)PUB | DOI | WoS | PubMed | Europe PMC
Quantifying microbial robustness in dynamic environments using microfluidic single-cell cultivation.
Microbial Cell Factories 23(1): 44. -
2023 | Preprint | Veröffentlicht | PUB-ID: 2985556Nieto C, Täuber S, Blöbaum L, Vahdat Z, Grünberger A, Singh A (2023)PUB | DOI | PubMed | Europe PMC
Coupling Cell Size Regulation and Proliferation Dynamics of Reveals Cell Division Based on Surface Area.
bioRxiv. -
2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2968932Steinhoff H, Finger M, Osthege M, Golze C, Schito S, Noack S, Buchs J, Grünberger A (2023)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Experimental ks estimation: A comparison of methods for Corynebacterium glutamicum from lab to microfluidic scale.
Biotechnology and Bioengineering 120(5): 1167-1449. -
2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2982187Blöbaum L, Täuber S, Grünberger A (2023)PUB | DOI | WoS | PubMed | Europe PMC
Protocol to perform dynamic microfluidic single-cell cultivation of C.glutamicum.
STAR Protocols 4(3): 102436. -
2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2969695Täuber S, Grünberger A (2023)PUB | DOI | WoS | PubMed | Europe PMC
Microfluidic single-cell scale-down systems: introduction, application, and future challenges.
Current Opinion in Biotechnology 81: 102915. -
2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2964098Täuber S, Blöbaum L, Steier V, Oldiges M, Grünberger A (2022)PUB | PDF | DOI | WoS | PubMed | Europe PMC | Preprint
Microfluidic single-cell scale-down bioreactors: A proof-of-concept for the growth of Corynebacterium glutamicum at oscillating pH values.
Biotechnology and Bioengineering 119(11): 3194-3209. -
2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2963033Smaluch K, Wollenhaupt B, Steinhoff H, Kolhheyer D, Grünberger A, Dusny C (2022)PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
Assessing the growth kinetics and stoichiometry of Escherichia coli at the single-cell level.
Engineering in Life Sciences . -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2962620Karsten L, Gött-Zink L, Schmitz J, Hoffrogge R, Grünberger A, Kottke T, Müller K (2022)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Genetically Encoded Ratiometric pH Sensors for the Measurement of Intra- and Extracellular pH and Internalization Rates.
Biosensors 12(5): 271. -
2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2967671Blöbaum L, Haringa C, Grünberger A (2022)PUB | DOI | WoS | PubMed | Europe PMC
Microbial lifelines in bioprocesses: From concept to application.
Biotechnology Advances 62. -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2963556Romanova N, Schmitz J, Strakeljahn M, Grünberger A, Bahnemann J, Noll T (2022)PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
Single-Cell Analysis of CHO Cells Reveals Clonal Heterogeneity in Hyperosmolality-Induced Stress Response.
Cells 11(11): 1763. -
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2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2962029Bahnemann J, Grünberger A (2022)PUB | DOI | PubMed | Europe PMC
Microfluidics in Biotechnology: Overview and Status Quo.
Advances in Biochemical Engineering, Biotechnology : 1-16. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2956409Schmitz J, Höving AL, Schmidt KE, Greiner J, Knabbe C, Kaltschmidt B, Grünberger A, Kaltschmidt C (2021)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Human Blood Serum Induces p38-MAPK- and Hsp27-Dependent Migration Dynamics of Adult Human Cardiac Stem Cells: Single-Cell Analysis via a Microfluidic-Based Cultivation Platform.
Biology 10(8): 708. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2956806Hermann KM, Grünberger A, Patel A (2021)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Formalin-casein enhances water absorbency of calcium alginate beads and activity of encapsulated Metarhizium brunneum and Saccharomyces cerevisiae.
World Journal of Microbiology and Biotechnology 37(9): 156. -
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2957323Täuber S, Blöbaum L, Wendisch VF, Grünberger A (2021)PUB | PDF | DOI | WoS | PubMed | Europe PMC | Preprint
Growth response and recovery of Corynebacterium glutamicum colonies on single-cell level upon defined pH stress pulses.
Frontiers in Microbiology 12: 711893. -
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2955090Schmitz J, Hertel O, Yermakov B, Noll T, Grünberger A (2021)PUB | PDF | DOI | WoS | PubMed | Europe PMC | Preprint
Growth and eGFP-production of CHO-K1 suspension cells cultivated from single-cell to laboratory scale.
Frontiers in Bioengineering and Biotechnology 9: 716343. -
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2021 | Zeitschriftenaufsatz | Im Druck | PUB-ID: 2957505Blombach B, Grünberger A, Centler F, Wierckx N, Schmid J (In Press)PUB | DOI | WoS | PubMed | Europe PMC
Exploiting unconventional prokaryotic hosts for industrial biotechnology.
Trends in biotechnology. -
2021 | Zeitschriftenaufsatz | Angenommen | PUB-ID: 2955245Stallmann D, Göpfert JP, Schmitz J, Grünberger A, Hammer B (Accepted)PUB | DOI | WoS | PubMed | Europe PMC
Towards an automatic analysis of CHO-K1 suspension growth in microfluidic single-cell cultivation.
Bioinformatics . -
2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2951549Schlembach I, Grünberger A, Rosenbaum MA, Regestein L (2021)PUB | DOI | WoS | PubMed | Europe PMC
Measurement Techniques to Resolve and Control Population Dynamics of Mixed-Culture Processes.
Trends in Biotechnology. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2957513Lenz P, Hilgers F, Burmeister A, Zimmermann L, Volkenborn K, Grünberger A, Kohlheyer D, Drepper T, Jaeger K-E, Knapp A (2021)PUB | DOI | WoS | PubMed | Europe PMC
The iSplit GFP assay detects intracellular recombinant proteins in Bacillus subtilis.
Microbial cell factories 20(1): 174. -
2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2955524Burmeister A, Akhtar Q, Hollmann L, Tenhaef N, Hilgers F, Hogenkamp F, Sokolowsky S, Marienhagen J, Noack S, Kohlheyer D, Grünberger A (2021)PUB | DOI | WoS | PubMed | Europe PMC
(Optochemical) Control of Synthetic Microbial Coculture Interactions on a Microcolony Level.
ACS synthetic biology. -
2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2955913Nguyen TM, Telek S, Zicler A, Martinez JA, Zacchetti B, Kopp J, Slouka C, Herwig C, Grünberger A, Delvigne F (2021)PUB | DOI | WoS | PubMed | Europe PMC
Reducing phenotypic instabilities of a microbial population during continuous cultivation based on cell switching dynamics.
Biotechnology and bioengineering. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949089Schmitz J, Täuber S, Westerwalbesloh C, von Lieres E, Noll T, Grünberger A (2021)PUB | Dateien verfügbar | DOI | WoS | PubMed | Europe PMC | Preprint
Development and application of a cultivation platform for mammalian suspension cell lines with single-cell resolution.
Biotechnology and Bioengineering 118(2): 992-1005. -
2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2951151Winkler S, Grünberger A, Bahnemann J (2021)PUB | DOI | PubMed | Europe PMC
Microfluidics in Biotechnology: Quo Vadis.
Advances in biochemical engineering/biotechnology: 1-26. -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2946333Della Corte D, van Beek HL, Syberg F, Schallmey M, Tobola F, Cormann KU, Schlicker C, Baumann PT, Krumbach K, Sokolowsky S, Morris CJ, Grünberger A, Hofmann E, Schroder GF, Marienhagen J (2020)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Engineering and application of a biosensor with focused ligand specificity.
Nature communications 11(1): 4851. -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2948721Ortseifen V, Viefhues M, Wobbe L, Grünberger A (2020)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Microfluidics for Biotechnology: Bridging Gaps to Foster Microfluidic Applications.
Frontiers in Bioengineering and Biotechnology 8: 589074. -
2020 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2948408Täuber S, Golze C, Ho P, von Lieres E, Grünberger A (2020)PUB | DOI | WoS | PubMed | Europe PMC
dMSCC: a microfluidic platform for microbial single-cell cultivation of Corynebacterium glutamicum under dynamic environmental medium conditions.
Lab on a chip. -
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2941821Täuber S, Lieres E, Grünberger A (2020)PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
Dynamic Environmental Control in Microfluidic Single‐Cell Cultivations: From Concepts to Applications.
Small 16(16): 1906670. -
2020 | Zeitschriftenaufsatz | Im Druck | PUB-ID: 2939030Burmeister A, Grünberger A (In Press)PUB | DOI | WoS | PubMed | Europe PMC
Microfluidic cultivation and analysis tools for interaction studies of microbial co-cultures.
Current opinion in biotechnology 62: 106-115. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2937575Hilgers F, Bitzenhofer NL, Ackermann Y, Burmeister A, Grünberger A, Jaeger K-E, Drepper T (2019)PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
Genetically Encoded Photosensitizers as Light-Triggered Antimicrobial Agents.
International journal of molecular sciences 20(18): 4608. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2936034Lindemann D, Westerwalbesloh C, Kohlheyer D, Grünberger A, von Lieres E (2019)PUB | DOI | WoS | PubMed | Europe PMC
Microbial single-cell growth response at defined carbon limiting conditions.
RSC ADVANCES 9(25): 14040-14050. -
2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2935887Sassi H, Nguyen TM, Telek S, Gosset G, Grünberger A, Delvigne F (2019)PUB | DOI | WoS | PubMed | Europe PMC
Segregostat: a novel concept to control phenotypic diversification dynamics on the example of Gram-negative bacteria.
Microbial biotechnology 12(5): 1064-1075. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935495Ho P, Westerwalbesloh C, Kaganovitch E, Grünberger A, Neubauer P, Kohlheyer D, Lieres E von (2019)PUB | DOI | WoS | PubMed | Europe PMC
Reproduction of Large-Scale Bioreactor Conditions on Microfluidic Chips.
Microorganisms 7(4): 105. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2937237Sachs CC, Koepff J, Wiechert W, Grünberger A, Noh K (2019)PUB | DOI | WoS | PubMed | Europe PMC
mycelyso - high-throughput analysis of Streptomyces mycelium live cell imaging data.
BMC bioinformatics 20(1): 452. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2934065Jager VD, Kloss R, Grünberger A, Seide S, Hahn D, Karmainski T, Piqueray M, Embruch J, Longerich S, Mackfeld U, Jaeger K-E, Wiechert W, Pohl M, Krauss U (2019)PUB | DOI | WoS | PubMed | Europe PMC
Tailoring the properties of (catalytically)-active inclusion bodies.
Microbial cell factories 18(1): 33. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2939585Dusny C, Grünberger A (2019)PUB | DOI | WoS | PubMed | Europe PMC
Microfluidic single-cell analysis in biotechnology: from monitoring towards understanding.
Current opinion in biotechnology 63: 26-33. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2937529Schmitz J, Grünberger A (2019)PUB
Ich sehe 'was, was du nicht siehst.
LABO 51(9): 30-33. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935496Westerwalbesloh C, Brehl C, Weber S, Probst C, Widzgowski J, Grünberger A, Pfaff C, Nedbal L, Kohlheyer D (2019)PUB | DOI | WoS | PubMed | Europe PMC
A microfluidic photobioreactor for simultaneous observation and cultivation of single microalgal cells or cell aggregates.
PloS one 14(4): e0216093. -
2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2933358Schmitz J, Noll T, Grünberger A (2019)PUB | DOI | WoS | PubMed | Europe PMC
Heterogeneity Studies of Mammalian Cells for Bioproduction. From Tools to Application.
Trends in Biotechnology 37(6): 645-660. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935584Theorell A, Seiffarth J, Grünberger A, Noeh K (2019)PUB | DOI | WoS | PubMed | Europe PMC
When a single lineage is not enough: Uncertainty-Aware Tracking for spatio-temporal live-cell image analysis.
BIOINFORMATICS 35(7): 1221-1228. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932955Burmeister A, Hilgers F, Langner A, Westerwalbesloh C, Kerkhoff Y, Tenhaef N, Drepper T, Kohlheyer D, von Lieres E, Noack S, Grünberger A (2019)PUB | DOI | WoS | PubMed | Europe PMC
A microfluidic co-cultivation platform to investigate microbial interactions at defined microenvironments.
LAB ON A CHIP 19(1): 98-110. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920273Kloss R, Limberg MH, Mackfeld U, Hahn D, Grünberger A, Jaeger VD, Krauss U, Oldiges M, Pohl M (2018)PUB | DOI | WoS | PubMed | Europe PMC
Catalytically active inclusion bodies of L-lysine decarboxylase from E. coli for 1,5-diaminopentane production.
SCIENTIFIC REPORTS 8(1): 5856. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932416Kampf J, Gerwig J, Kruse K, Cleverley R, Dormeyer M, Grünberger A, Kohlheyer D, Commichau FM, Lewis RJ, Stuelke J (2018)PUB | DOI | WoS | PubMed | Europe PMC
Selective Pressure for Biofilm Formation in Bacillus subtilis: Differential Effect of Mutations in the Master Regulator SinR on Bistability.
mBio 9(5): e01464-18. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920685Mosheiff N, Martins BMC, Pearl-Mizrahi S, Grünberger A, Helfrich S, Mihalcescu I, Kohlheyer D, Locke JCW, Glass L, Balaban NQ (2018)PUB | DOI | WoS
Inheritance of Cell-Cycle Duration in the Presence of Periodic Forcing.
PHYSICAL REVIEW X 8(2): 15. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932764Koepff J, Sachs CC, Wiechert W, Kohlheyer D, Noeh K, Oldiges M, Grünberger A (2018)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Germination and Growth Analysis of Streptomyces lividans at the Single-Cell Level Under Varying Medium Compositions.
FRONTIERS IN MICROBIOLOGY 9: 2680. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2930515Hage-Huelsmann J, Grünberger A, Thies S, Santiago-Schuebel B, Klein AS, Pietruszka J, Binder D, Hilgers F, Domroese A, Drepper T, Kohlheyer D, Jaeger K-E, Loeschcke A (2018)PUB | DOI | WoS | PubMed | Europe PMC
Natural biocide cocktails: Combinatorial antibiotic effects of prodigiosin and biosurfactants.
PLOS ONE 13(7): e0200940. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2919078Hornung R, Grünberger A, Westerwalbesloh C, Kohlheyer D, Gompper G, Elgeti J (2018)PUB | DOI | WoS | PubMed | Europe PMC
Quantitative modelling of nutrient-limited growth of bacterial colonies in microfluidic cultivation.
JOURNAL OF THE ROYAL SOCIETY INTERFACE 15(139): 11. -
2018 | Konferenzbeitrag | PUB-ID: 2933363Schmitz J, Noll T, Grünberger A (2018)PUB
Towards Microfluidic Single-Cell Cultivation of Mammalian Cell Lines.
Presented at the Young Scientist Cell Culture Biotechnology Retreat, Laupheim. -
2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933359Schmitz J, Kerkhoff Y, Noll T, Kohlheyer D, Grünberger A (2018)PUB
Towards dynamic single-cell cultivation systems for industrially relevant mammalian cell lines.
Presented at the BioProcessing Days 2018, Recklinghausen. -
2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933362Schmitz J, Kerkhoff Y, Noll T, Grünberger A (2018)PUB
Dynamic microfluidical single-cell cultivation of mammalian cell lines. From experiment to analysis.
Presented at the CeBiTec Symposium 2018, Bielefeld. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932765Kloss R, Karmainski T, Jaeger VD, Hahn D, Grünberger A, Baumgart M, Krauss U, Jaeger K-E, Wiechert W, Pohl M (2018)PUB | DOI | WoS
Tailor-made catalytically active inclusion bodies for different applications in biocatalysis.
CATALYSIS SCIENCE & TECHNOLOGY 8(22): 5816-5826. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2931505Jaeger VD, Lamm R, Kloss R, Kaganovitch E, Grünberger A, Pohl M, Buechs J, Jaeger K-E, Krauss U (2018)PUB | DOI | WoS | PubMed | Europe PMC
A Synthetic Reaction Cascade Implemented by Colocalization of Two Proteins within Catalytically Active Inclusion Bodies.
ACS SYNTHETIC BIOLOGY 7(9): 2282-2295. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2919063Dormeyer M, Lentes S, Ballin P, Wilkens M, Klumpp S, Kohlheyer D, Stannek L, Grünberger A, Commichau FM (2018)PUB | DOI | WoS | PubMed | Europe PMC
Visualization of tandem repeat mutagenesis in Bacillus subtilis.
DNA REPAIR 63: 10-15. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912521Grünberger A, Schöler K, Probst C, Kornfeld G, Hardiman T, Wiechert W, Kohlheyer D, Noack S (2017)PUB | DOI | WoS | PubMed | Europe PMC
Real-time monitoring of fungal growth and morphogenesis at single-cell resolution.
Engineering in life sciences 17(1): 86–92. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912738Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D, von Lieres E (2017)PUB | DOI | WoS | PubMed | Europe PMC
Coarse-graining bacteria colonies for modelling critical solute distributions in picolitre bioreactors for bacterial studies on single-cell level.
Microbial Biotechnology 10(4): 845-857. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916519Binder D, Drepper T, Jaeger K-E, Delvigne F, Wiechert W, Kohlheyer D, Grünberger A (2017)PUB | DOI | WoS | PubMed | Europe PMC
Homogenizing bacterial cell factories: Analysis and engineering of phenotypic heterogeneity.
METABOLIC ENGINEERING 42: 145-156. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912503Rudat A, Wiechert W, Kohlheyer D, Grünberger A (2017)PUB
Picoliter bioreactors for microbial consortia: From proof of concept to first application.
Presented at the Himmelfahrtstagung 2017: Models for Developing and Optimising Biotech Production, Neu-Ulm, Germany. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912508Burmeister A, Bitzenhofer NL, Grünberger A, Binder D, Drepper T, Wiechert W, Kohlheyer D (2017)PUB
Microfluidic heterogeneity analysis of fluorescence-based gene expression of industrially relevant production strains on single-cell level.
Presented at the BioProcessing Days 2017, Recklinghausen, Germany. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912759Grünberger A (2017)PUB
Microfluidic Single-Cell Cultivation: A key for next generation bioprocess development?
Presented at the FFBiotech Symposium - Innovative approaches in bioreactors design and operation, Lille, France. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912771Rudat A, Noack S, Wiechert W, Kohlheyer D, Grünberger A (2017)PUB
Microfluidic single-cell (co-)cultivation: Exploring the next dimension.
Presented at the Data-driven Biotechnology - bench, bioreactor and bedside, Copenhagen, Denmark. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912502Jäger VD, Longerich S, Dietrich M, Kloss R, Grünberger A, Pohl M, Jaeger K-E, Krauss U (2017)PUB
Functionally-active protein aggregates - towards the realization of an enzyme cascade in catalytically-active inclusion bodies.
Presented at the BioTrans 2017, Budapest, Hungary. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912505Sachs CC, Koepff J, Kohlheyer D, Wiechert W, Oldiges M, Nöh K, Grünberger A (2017)PUB
Microfluidic single-cell cultivation of S. lividans: Uncovering heterogeneity in filamentous growth.
Presented at the DECHEMA-Tagung "Systems Biology meets Synthetic Biology", Frankfurt, Germany. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912507Rudat A, Wiechert W, Kohlheyer D, Grünberger A (2017)PUB
Spatiotemporal analysis of synthetic microbial communities at the single-cell level in microfluidic interaction compartments.
Presented at the 6th International Conference on Microbial Communication for Young Scientists, Jena, Germany. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912501Kloss R, Limberg M, Jäger VD, Mackfeld U, Karmainski T, Grünberger A, Krauss U, Pohl M (2017)PUB
Catalytically active inclusion bodies. A novel carrier-free Enzyme Immobilisation method.
Presented at the BioTrans 2017, Budapest, Hungary. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912506Sachs CC, Grünberger A, Probst C, Wiechert W, Kohlheyer D, Nöh K (2017)PUB
Integrated High-Throughput Platform for Microfluidic Live-Cell Analysis with Feed-Back Eyperimentation.
Presented at the DECHEMA-Tagung "Systems Biology meets Synthetic Biology", Frankfurt, Germany. -
2017 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912518Kaganovitch E, Krischer M, Probst C, Grünberger A, Zunic E, Freier C, Wiechert W, Kohlheyer D (2017)PUB
Microfluidic device for control and sensing of dynamic oxygen levels during cell cultivation.
In: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016). Red Hook, NY: Curran Associates, Inc.: 355-356. -
2017 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2912520Ladner T, Grünberger A, Probst C, Kohlheyer D, Büchs J, Delvigne F (2017)PUB | DOI
Application of Mini- and Micro-Bioreactors for Microbial Bioprocesses.
In: Current Developments in Biotechnology and Bioengineering. Larroche C, Sanromán MÁ, Du G, Pandey A (Eds); Amsterdam: Elsevier: 433-461. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912737Delvigne F, Baert J, Sassi H, Fickers P, Grünberger A, Dusny C (2017)PUB | DOI | WoS | PubMed | Europe PMC
Taking control over microbial populations: Current approaches for exploiting biological noise in bioprocesses.
Biotechnology Journal 12(7): 1600549. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912504Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D, von Lieres E (2017)PUB
Models for Developing and Optimizing Microscale Bacteria Cultivation.
Presented at the Himmelfahrtstagung 2017: Models for Developing and Optimising Biotech Production, Neu-Ulm, Germany. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912509Rudat A, Wiechert W, Kohlheyer D, Grünberger A (2017)PUB
Microfluidic cultivation chamber for the investigation of synthetic microbial co-cultures on single-cell level: From the development to first application.
Presented at the BioProcessing Days 2017, Recklinghausen, Germany. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912514Binder D, Probst C, Grünberger A, Hilgers F, Loeschcke A, Jaeger K-E, Kohlheyer D, Drepper T (2016)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Comparative Single-Cell Analysis of Different E. coli Expression Systems during Microfluidic Cultivation.
PLoS one 11(8): e0160711. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912522Sachs CC, Grünberger A, Helfrich S, Probst C, Wiechert W, Kohlheyer D, Nöh K (2016)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Image-Based Single Cell Profiling: High-Throughput Processing of Mother Machine Experiments.
PLoS one 11(9): e0163453. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912513Kusen PM, Wandrey G, Probst C, Grünberger A, Holz M, Meyer zu Berstenhorst S, Kohlheyer D, Büchs J, Pietruszka J (2016)PUB | DOI | WoS | PubMed | Europe PMC
Optogenetic Regulation of Tunable Gene Expression in Yeast Using Photo-Labile Caged Methionine.
ACS chemical biology 11(10): 2915-2922. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912527Grünberger A (2016)PUB
Microfluidic single-cell cultivation: Is small the new beautiful?
Presented at the 6th International Bielefeld-CeBiTec Research Conference: Advances in Industrial Biotechnology: New Techniques, Substrates and Products for Bioprocesses, Bielefeld, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912534Grünberger A (2016)PUB
Single-cell microfluidics for bioprocess development.
Presented at the GreenWin Conferences “Green Chemistry and White Biotechnology", Gembloux, Belgium. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912539Westerwalbesloh C, Grünberger A, Stute B, Weber S, Wiechert W, Kohlheyer D, von Lieres E (2016)PUB
Nutrient distribution in perfusion based picoliter bioreactors.
Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912820Hage-Hülsmann J, Grünberger A, Thies S, Domröse A, Klein A, Binder D, Hilgers F, Kohlheyer D, Pietruszka J, Jaeger K-E, Drepper T, Loeschcke A (2016)PUB
Combinatorial antibiotic effects of natural biocide cocktails.
Presented at the IV International Conference on Antimicrobial Research, Malaga, Spain. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912761Grünberger A (2016)PUB
Microfluidic single-cell bioreactors. Introduction, application and future perspectives.
Presented at the LCSB Biannual Minisymposia in Modelling/Automation/Microfluidics at the University of Luxembourg, Esch-sur-Alzette, Luxembourg. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912803Binder D, Bier C, Grünberger A, Hilgers F, Loeschcke A, Kohlheyer D, Pietruszka J, Jaeger KE, Drepper T (2016)PUB
Employing photocaged carbohydrates in light-controlled cell factories for synthetic bio(techno)logy and single cell applications.
Presented at the Annual Conference of the Association for General and Applied Microbiology (VAAM),, Jena, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912512Bier C, Binder D, Grünberger A, Drobietz D, Hage-Hülsmann J, Kohlheyer D, Löschcke A, Jaeger K-E, Drepper T, Pietruszka J (2016)PUB
Sugar Based Caged Compounds for Biotechnological Synthetic Biological Applications.
Presented at the 26th IUPAC Symposium on Photochemistry, Osaka, Japan. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912524Brehl C, Grünberger A, Probst C, Pfaff C, Wiechert W, Behrendt D, Kohlheyer D (2016)PUB
Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environments.
Presented at the 9. DECHEMA Bundesalgenstammtisch, Jülich, Germany. -
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912529Grünberger A, Steffens I, Binder D, Drepper T, Wiechert W, Kohlheyer D (2016)PUB
Microbial metabolic state diagrams: Using microfluidic single-cell cultivation to predict bacterial gene expresssion.
Presented at the EMBL Conference Microfluidics, Heidelberg, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912531Westerwalbesloh C, Grünberger A, Kohlheyer D, von Lieres E (2016)PUB
Modeling inhomogeneities across cultivation chamber arrays in single-cell cultivation devices.
Presented at the EMBL Conference Microfluidics, Heidelberg (Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912536Sachs CC, Probst C, Grünberger A, Wiechert W, Frunzke J, Kohlheyer D, Nöh K (2016)PUB
An integrated platform for dynamic microfluidic experimentation with single-cell resolution.
Presented at the DECHEMA-Tagung 'Single Cell Technologies 2016', Frankfurt, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912538Steffens I, Grünberger A, Binder D, Drepper T, Wiechert W, Kohlheyer D (2016)PUB
Bacterial phase diagrams. Analyzing and predicting cell-to-cell heterogeneity of microbial gene expression.
Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin (Germany). -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912540Grünberger A, Steffens I, Binder D, Drepper T, Wiechert W, Kohlheyer D (2016)PUB
Bacterial phase diagrams – Using engineering concepts to predict cell-to-cell heterogeneity of microbial gene expression.
Presented at the Jahrestagung 2016 der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Jena, Germany. -
2016 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912552Probst C, Freier C, Mahr R, Grünberger A, Helfrich S, Wiechert W, Nöh K, Frunzke J, Kohlheyer D (2016)PUB
Closing the gap between microfluidic single-cell analysis and bioprocess development for microbial organisms.
In: 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015). Red Hook, NY: Curran Associates, Inc.: 537-539. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912525Burmeister A, Bitzenhofer NL, Grünberger A, Binder D, Drepper T, Wiechert W (2016)PUB
Microfluidic heterogeneity analysis of fluorescence-based gene expression of industrially relevant production strains on single-cell level.
Presented at the 18. Heiligenstädter Kolloquium „Technische Systeme für die Lebenswissenschaften, Heiligenstadt, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912532Westerwalbesloh C, Grünberger A, Stute B, Weber S, Kohlheyer D, von Lieres E (2016)PUB
Characterizing substrate availability within microfluidic tools employed for the analysis of genetically modified single cells.
Presented at the 1. International Conference on Molecular Interaction Engineering (MIE), Karlsruhe, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912537Grünberger A, Wiechert W, Kohlheyer D (2016)PUB
Bioprocesses under magnification. Learning from single cells about large-scale processes.
Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin, Germany. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912544Binder D, Bier C, Grünberger A, Drobietz D, Hage-Hülsmann J, rey G, Büchs J, Kohlheyer D, Loeschcke A, Wiechert W, Jaeger K-E, Pietruszka J, Drepper T (2016)PUB | DOI | WoS | PubMed | Europe PMC
Photocaged Arabinose - A Novel Optogenetic Switch for Rapid and Gradual Control of Microbial Gene Expression.
ChemBioChem 17(4): 296-299. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912739Li S, Jendresen CB, Grünberger A, Ronda C, Jensen SI, Noack S, Nielsen AT (2016)PUB | DOI | WoS | PubMed | Europe PMC
Enhanced protein and biochemical production using CRISPRi-based growth switches.
Metabolic Engineering 38: 274-284. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912760Grünberger A (2016)PUB
Picoliter bioreactors for microbial consortia: A novel concept to investigate microbial interactions at the single-cell level.
Presented at the SynComBio Workshop “Applications of synthetic microbial communities in bioeconomy", Düsseldorf, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912772Grünberger A, Sachs C, Kohlheyer D, Wiechert W, Nöh K (2016)PUB
Spatio-temporal analysis of bacterial populations at single-cell level.
Presented at the IBG Modelling Workshop, Jülich, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912511Bier C, Binder D, Grünberger A, Drobietz D, Kohlheyer D, Löschcke A, Jaeger K-E, Drepper T, Pietruszka J (2016)PUB
Photocaged Carbohydrates: Versatile Tools for Biotechnological Applications.
Presented at the 18th International Conference on Photochemistry, Paris, France. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912523Brehl C, Grünberger A, Probst C, Pfaff C, Wiechert W, Behrendt D, Kohlheyer D (2016)PUB
Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environments.
Presented at the ProcessNet 2016, Aachen, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912530Kaganovitch E, Probst C, Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D (2016)PUB
Single-cell analysis of E. coli in microfluidic batch reactors.
Presented at the EMBL Conference Microfluidics, Heidelberg (Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912535Grünberger A, Steffens I, Binder D, Drepper T, Wiechert W, Kohlheyer D (2016)PUB
Bacterial phase diagrams: A novel concept to predict and control bacterial gene expression.
Presented at the DECHEMA-Himmelfahrtstagung: New Frontiers for Biotech Processes, Koblenz, Germany. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904866Binder D, Frohwitter J, Mahr R, Bier C, Grünberger A, Loeschcke A, Peters-Wendisch P, Kohlheyer D, Pietruszka J, Frunzke J, Jaeger K-E, Wendisch VF, Drepper T (2016)PUB | DOI | WoS | PubMed | Europe PMC
Light-controlled cell factories – Employing photocaged IPTG for light-mediated optimization of lac-based gene expression and (+)-valencene biosynthesis in Corynebacterium glutamicum.
Appl Environ Microbiol 82(20): 6141-6149. -
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912568Dusny C, Grünberger A, Probst C, Wiechert W, Kohlheyer D, Schmid A (2015)PUB | DOI | WoS | PubMed | Europe PMC
Technical bias of microcultivation environments on single cell physiology.
Lab on a chip 15(8): 1822-1834. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912550Grünberger A, Probst C, Helfrich S, Nanda A, Stute B, Wiechert W, von Lieres E, Nöh K, Frunzke J, Kohlheyer D (2015)PUB | DOI | WoS | PubMed | Europe PMC
Spatiotemporal microbial single-cell analysis using a high-throughput microfluidics cultivation platform.
Cytometry / A 87(12): 1101–1115. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912554Krämer CEM, Singh A, Helfrich S, Grünberger A, Wiechert W, Nöh K, Kohlheyer D (2015)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Non-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl Ester.
PLoS one 10(10): e0141768. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912555Helfrich S, Azzouzi CE, Probst C, Seiffarth J, Grünberger A, Wiechert W, Kohlheyer D, Nöh K (2015)PUB | DOI | WoS | PubMed | Europe PMC
Vizardous: interactive analysis of microbial populations with single cell resolution.
Bioinformatics 31(23): 3875-3877: btv468. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912557Westerwalbesloh C, Grünberger A, Stute B, Weber S, Wiechert W, Kohlheyer D, von Lieres E (2015)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Modeling and CFD Simulation of nutrient Distribution in picoliter bioreactors for bacterial growth studies on single-cell level.
Lab on a chip 15(21): 4177-4186. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912541Binder D, Bier C, Grünberger A, Loeschcke A, Kohlheyer D, Pietruszka J, Jaeger K-E, Drepper T (2015)PUB
Light-controlled cell factories - Employing optogenetic plug-and-play expression modules based on photocaged carbohydrates for synthetic bio(techno)logy and single cell applications.
Presented at the ESP Photobiology conference, Aveiro, Portugal. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912546Grünberger A, Wiechert W, Kohlheyer D (2015)PUB
Single-cell microfluidics: A key technology to understand life at environmental defined conditions.
Presented at the Kick-off Konferenz: Leben? - Eine neue Förderinitiative stellt sich vor, Hannover, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912560Zunic E, Schechtel A, Probst C, Grünberger A, Freier C, Seibold G, Wiechert W, Kohlheyer D (2015)PUB
Dynamic environmental control in microfluidic devices for single-cell Analysis of biological production processes.
Presented at the Kolloquium Synthetic Biology - Opportunities for Interdisciplinary Research from Biology to Engineering, Aachen, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912565Grünberger A, Probst C, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2015)PUB
Single-cell microfluidics meets applied biotechnology. From expectation to application.
Presented at the Conference "Cell Factories and Biosustainability - Technologies for Cell Factory Construction", Hillerod, Denmark. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912773Grünberger A, Probst C, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2015)PUB
Single-cell microfluidics meets applied biotechnology. From expectation to application.
Presented at the Jahreskongress Biotechnologie 2020+, Berlin, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912545Loeschcke A, Thies S, Hage-Hülsmann J, Grünberger A, Binder D, Domröse A, Klein A, Kohlheyer D, Pietruszka J, Jaeger K-E, Drepper T (2015)PUB
Heterologous production of antibacterial secondary metabolites from Serratia marcescens in Pseudomonas putida.
Presented at the 6th Congress of European Microbiologists (FEMS 2015), Maastricht, Netherlands. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912548Bier C, Binder D, Grünberger A, Drobietz D, Hage-Hülsmann J, Kohlheyer D, Loeschke A, Jaeger K-E, Drepper T, Pietruszka J (2015)PUB
Caged Compounds for Biotechnological and Synthetic Biological Applications.
Presented at the European Society for Photobiology 2015 Congress, Aveiro, Portugal. -
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912567Grünberger A (2015)PUB
Single-cell bioreactors: Improving the understanding of microbial metabolism.
Presented at the 30. Jahrestagung der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Marburg (Germany. -
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912549Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2015)PUB
Metabolite biosensors for single cell Analysis and the Evolution of production strains.
Presented at the 30. Jahrestagung der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Marburg, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912551Probst C, Grünberger A, Krämer C, Sachs CC, Wiechert W, Baumgart M, Kohlheyer D (2015)PUB
Genetically encoded sensor analysis with spatial and temporal Resolution by time-lapse imaging.
Presented at the 1st Evaluation Symposium, Molecular Interaction Engineering, MIE-Project, Karlsruhe, Germany. -
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912563Sachs CC, Helfrich S, Grünberger A, Probst C, Wiechert W, Kohlheyer D, Nöh K (2015)PUB
High-throughput, long-term growth characterization of C. glutamicum on single cell level using the Mother Machine.
Presented at the 3rd International Conference of the Cluster of Excellence Tailor-Made Fuels from Biomass, Aachen, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912804Krämer C, Helfrich S, Singh A, Grünberger A, Wiechert W, Nöh K, Kohlheyer D (2015)PUB
Instantaneous microfluidic metabolic activity sensing for non-invasive single cell physiology analysis of a prokaryote and its descendants.
Presented at the 3nd International Conference IMPLEMENTATION OF MICROREACTOR TECHNOLOGY INTO BIOTECHNOLOGY (IMTB 2015), Opatija, Croatia. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912763Grünberger A (2015)PUB
Microfluidic Single-Cell Cultivation: The key for next generation bioprocess development?
Presented at the Colloquium Biotechnology, Technical Faculty - Bielefeld University, Bielefeld. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912542Probst C, Grünberger A, Binder D, Steffen I, Wiechert W, Kohlheyer D (2015)PUB
Optical control of gene expression in bacteria on the single-cell level by caged compounds.
Presented at the Synthetic Biology: Opportunities for Interdisciplinary Research from Biology to Engineering, Aachen, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912559Sachs CC, Helfrich S, Grünberger A, Probst C, Wiechert W, Kohlheyer D, Nöh K (2015)PUB
High-throughput long-term growth characterization of C. glutamicum on single cell using the Mother Machine.
Presented at the Colloquium Synthetic Biology - Opportunities for Interdisciplinary Research from Biology to Engineering, Aachen, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912566Grünberger A, Probst C, Wiechert W, Kohlheyer D (2015)PUB
Single-Cell Bioreactors: Cutting Edge Cultivation Devices for the Ultimate Scale-Down of Bioprocesses.
Presented at the DECHEMA-Himmelfahrtstagung "Scale-up and scale-down of bioprocesses", Hamburg-Bergedorf, Germany. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912605Schendzielorz G, Dippong M, Grünberger A, Kohlheyer D, Yoshida A, Binder S, Nishiyama C, Nishiyama M, Bott M, Eggeling L (2014)PUB | DOI | WoS | PubMed | Europe PMC
Taking Control over Control: Use of Product Sensing in Single Cells to Remove Flux Control at Key Enzymes in Biosynthesis Pathways.
ACS Synthetic Biology 3(1): 21–29. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912594Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger K-E, Drepper T (2014)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Light-responsive control of bacterial gene Expression: precise triggering of the lac promoter activity using photocaged IPTG.
Integrative biology 6(8): 755-765. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912573Mustafi N, Grünberger A, Mahr R, Helfrich S, Nöh K, Blombach B, Kohlheyer D, Frunzke J (2014)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Application of a Genetically Encoded Biosensor for Live Cell Imaging of L-Valine Production in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains.
PLoS one 9(1): e85731. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912589Helfrich S, Krämer C, Grünberger A, Azzouzi CE, Pfeifer E, Frunzke J, Wiechert W, Kohlheyer D, Nöh K (2014)PUB
Microfluids as platform for the spatiotemporal analysis of bacterial populations at single-cell level.
Presented at the 30th Symposium "Mechanisms of Gene Regulation" of the VAAM study group "Regulation & Signal Transduction in Prokaryotes", Düsseldorf, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912591Grünberger A, Probst C, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2014)PUB
Microfluidic Single-Cell Cultivation: Opportunity for Industrial Bioprocess Development.
Presented at the EMBL Conference – Microfluidics 2014, Heidelberg, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912596Grünberger A, Probst C, Unthan S, Mustafi N, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2014)PUB
Single-cell cultivation in picoliter scale: Opportunity for bioprocess development.
Presented at the 3rd BioProScale Symposium, Berlin, Germany. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912616Unthan S, Grünberger A, van Ooyen J, Gätgens J, Heinrich J, Paczia N, Wiechert W, Kohlheyer D, Noack S (2014)PUB | DOI | WoS | PubMed | Europe PMC
Beyond growth rate 0.6. What drives Corynebacterium glutamicum to higher growth rates in defined medium.
Biotechnology and bioengineering 111(2): 359–371. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912806Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jäger K-E, Drepper T (2014)PUB
Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducers.
Presented at the 30th Symposium „Mechanisms of gene regulation”, Düsseldorf, Germany. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912730Nanda AM, Heyer A, Kramer C, Grünberger A, Kohlheyer D, Frunzke J (2014)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Analysis of SOS-Induced Spontaneous Prophage Induction in Corynebacterium glutamicum at the Single-Cell Level.
Journal of Bacteriology 196(1): 180-188. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912766Grünberger A (2014)PUB
Picoliter Bioreactors. Learning from Single Cells about Large Scale Processes.
Presented at the iGEM Meetup, Aachen, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912805Kohlheyer D, Grünberger A, Weber S, Nedbal L, Wiechert W (2014)PUB
Microfluidic Single-Cell Analysis – Potential for Microalgae Research?
Presented at the BioSC Workshop | Exploration "Perspectives of Algal Technologies", Jülich, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912808Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)PUB
Metabolite biosensors for single cell analysis and the development of production strains.
Presented at the 30th Symposium „Mechanisms of gene regulation”, Düsseldorf, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912586Helfrich S, Azzouzi CE, Krämer C, Pfeifer E, Grünberger A, Mustafi N, Wiechert W, Frunzke J, Kohlheyer D, Nöh K (2014)PUB
Microbial Populations on the Microfluidic Analyst's Couch: Approaching Cellular Heterogeneity.
Presented at the BioImage Informatics 2014, Leuven, Belgium. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912588Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2014)PUB
Investigating single-cell growth of microbial cell factories: is counting cells enough?
Presented at the 2nd International Workshop on Image-based Systems Biology, Jena (Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912590Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)PUB
Transcription factor-based biosensor for microbial strain development.
Presented at the 30th Symposium "Mechanisms of Gene Regulation" of the VAAM study group "Regulation & Signal Transduction in Prokaryotes", Düsseldorf, Germany. -
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912595Kohlheyer D, Grünberger A, Probst C, Helfrich S, Frunzke J, Eggeling L, Nöh K, Noack S, Wiechert W (2014)PUB
Single-cell Bioreactors boost Bioprocess Development: New Insights into Cellular Metabolism.
Presented at the Metabolic Engineering X, Vancouver, Canada. -
2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912601Grünberger A, Schmitz K, Probst C, Noack S, Wiechert W, Kohlheyer D (2014)PUB
Simple microfluidics for complex organisms: A microfluidic chip System for growth and Morphogenesis studies of filamentous fungi.
In: 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013). Red Hook, NY: Curran. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912569Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger K-E, Drepper T (2014)PUB
Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducers.
Presented at the VAAM Jahrestagung, Dresden, Germany. -
2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912571Grünberger A, Probst C, Helfrich S, Frunzke J, Noack S, Nöh K, Wiechert W, Kohlheyer D (2014)PUB
Microfluidic Single-Cell Analysis Platform for Biotechnological Process Development.
In: MicroTAS 2014. San Diego, California: CBM Society: 3 p. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912576Dusny C, Grünberger A, Wiechert W, Kohlheyer D, Schmid A (2014)PUB
From extracellular Environment to functional phenotype. Quantitative comparison of single cell physiology in static and steady environments.
Presented at the 3rd BioProScale Symposium "Inhomogeneities in large-scale bioprocesses. System biology and process dynamics", Berlin, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912583Grünberger A, Probst C, Wiechert W, Kohlheyer D (2014)PUB
Picoliter Bioreactors. Learning from Single Cells about Large-Scale Bioprocesses.
Presented at the 24th Annual conference of the German Society for Cytometry, Dresden, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912587Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)PUB
Metabolite biosensors for single cell analysis and the development of production strains.
Presented at the Gemeinsame Jahrestagung der Deutschen Gesellschaft für Hygiene und Mikrobiologie und der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Dresden, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912575Krämer C, Helfrich S, Azzouzi CE, Grünberger A, Pfeifer E, Frunzke J, Wiechert W, Nöh K, Kohlheyer D (2014)PUB
Microfluidics as platform for the spatiotemporal analysis of bacterial populations at single-cell level.
Presented at the International Meeting, Phenotypic heterogeneity and sociobiology of bacterial populations, Irsee, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912582Grünberger A, Probst C, Nanda A, Frunzke J, Wiechert W, Kohlheyer D (2014)PUB
Microfluidic Single-Cell Cultivation Systems: Versatile Tools for Microbiology.
Presented at the 4th Annual Conference of the Association for General and Applied Microbiology, Dresden, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912823Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)PUB
Application of a genetically-encoded metabolite sensor for single cell analysis and development of production strains.
Presented at the Metabolic engineering X, Vancouver, Canada. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912814Grünberger A, Probst C (2014)PUB
Introduction into Microfluidic Single-Cell Analysis.
Presented at the Biology feat, Engineering – SYNBIO – Single Cell Analysis in Microfluidic Devices (Workshop), Jülich, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912585Sachs CC, Grünberger A, Wiechert W, Nöh K, Kohlheyer D (2014)PUB
Robust Automated Image Analysis of Mother Machine Microfluidic Growth Devices.
Presented at the BioImage Informatics 2014, Leuven, Belgium. -
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912597Grünberger A, Wiechert W, Kohlheyer D (2014)PUB | DOI | WoS | PubMed | Europe PMC
Single-cell microfluidics: opportunity for bioprocess development.
Current opinion in biotechnology 29: 15-23. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912580Dusny C, Grünberger A, Rosenthal K, Wiechert W, Schmid A (2014)PUB
Quantitative Physiology of Single Cells for Linking Phenotype and Environment.
Presented at the 24th Annual Conference of the German Society for Flow Cytometry, Dresden, Germany. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912599Grünberger A, Probst C, Heyer A, Wiechert W, Frunzke J, Kohlheyer D (2013)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation.
Journal of visualized experiments. Bioengineering 82(82): e50560. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912606Hoffmann K, Grünberger A, Lausberg F, Bott M, Eggeling L (2013)PUB | DOI | WoS | PubMed | Europe PMC
Visualization of Imbalances in Sulfur Assimilation and Synthesis of Sulfur-Containing Amino Acids at the Single-Cell Level.
Applied and environmental microbiology 79(21): 6730-6736. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912604Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)PUB
Application of a genetically encoded biosensor for single cell analysis and strain development of production strains.
Presented at the New concepts and approaches in microbiology, Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912609Nanda A, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)PUB
Single-cell Dynamics of the SOS Response in Corynebacterium glutamicum.
Presented at the Bacterial Networks, Pultusk, Poland. -
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912623Heyer A, Nanda A, Grünberger A, Kohlheyer D, Frunzke J (2013)PUB
Spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the VAAM-Tagung 2013, Bremen, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912630Kohlheyer D, Grünberger A, Probst C, Krämer C, Eggeling L, Frunzke J, Wiechert W (2013)PUB
Microbial single cell analysis of production strains in microfabricated habitats.
Presented at the DECHEMA-Workshop Microfluidics for Systems Biology and Bioprocess Development, Frankfurt, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912825Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)PUB
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
Presented at the Jülich Biotech Day, Jülich, Germany. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912745Grünberger A, Lai P-K, Blanco MA, Roberts CJ (2013)PUB | DOI | WoS | PubMed | Europe PMC
Coarse-Grained Modeling of Protein Second Osmotic Virial Coefficients: Sterics and Short-Ranged Attractions.
The Journal of Physical Chemistry B 117(3): 763-770. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912810Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2013)PUB
Analysis of microbial observables on single cell level: Challenges of Cell Clusters for Microscopy-based Image Processing.
Presented at the 9th European Congress of Chemical Engineering (ECCE9)/ 2nd European Congress of Applied Biotechnology (ECAB2), The Hague, Netherlands. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912824Nanda AM, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)PUB
Single-cell dynamics of the SOS response in Corynebacterium glutamicum.
Presented at the Jülich Biotech Day, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912827Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)PUB
Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains.
Presented at the Jülich Biotech Day, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912829Sachs C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)PUB
Automated image analysis pipeline for single cell bacterial growth studies.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912834Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)PUB
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912836Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)PUB
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
Presented at the New Approaches and Concepts in Microbiology, Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912603Grünberger A, Probst C, Unthan S, Krämer C, Paczia N, Noack S, Wiechert W, Kohlheyer D (2013)PUB
Single Cell Bioreactors for Bioprocess Optimization.
Presented at the Jülich Biotech Day 2013, Jülich,Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912608Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)PUB
SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the Jülich Biotech Day 2013, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912613Probst C, Grünberger A, Frunzke J, Wiechert W, Kohlheyer D (2013)PUB
Microfluidic cultivation technology and application: analysing single-microbes under perfect environmental control.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912615Helfrich S, Azzouzi CE, Grünberger A, Wiechert W, Nöh K (2013)PUB
Explorative Analysis of Cell Population Development: Customizable Interactive Lineage Trees.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912618Kohlheyer D, Grünberger A, Probst C, Frunzke J, Wiechert W (2013)PUB
Picoliter fermentation with single bacteria: Learning from the one to unravel the crowd.
Presented at the 2nd International Congress Implementation of Microreactor Technology in Biotechnology, Cavtat, Croatia. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912620Noack S, Grünberger A, van Ooyen J, Kohlheyer D, Wiechert W (2013)PUB
Increasing biomass productivity of C. glutamicum - new insights from microscale cultivations.
Presented at the 9th European Congress of Chemical Engineering, Den Haag, The Netherlands. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912622Wiechert W, Kohlheyer D, Noack S, Frunzke J, Mustafi N, Grünberger A (2013)PUB
Picoliter Bioreactors. Learning from Single Cells about Large Scale Processes.
Presented at the Copenhagen Bioscience Conferences, Cell Factories and Biosustainability, Favrholm, Denmark. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912625Heinrich J, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)PUB
Single cell growth under constant environmental conditions and defined C sources: A case study for Corynebacterium glutamicum.
Presented at the VAAM-Tagung 2013, Bremen, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912627Probst C, Frank P, Grünberger A, Wiechert W, Kohlheyer D (2013)PUB
Time lapse microbial single cell analysis in a micro fabricated batch reactor.
Presented at the Single Cell Analysis Europe 2013, Barcelona, Spain. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2614036Baumgart M, Unthan S, Rückert C, Sivalingam J, Grünberger A, Kalinowski J, Bott M, Noack S, Frunzke J (2013)PUB | DOI | WoS | PubMed | Europe PMC
Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 - a platform strain for basic research and industrial biotechnology.
Applied and environmental microbiology 79(19): 6006-6015. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912602Grünberger A, Helfrich S, Mustafi N, Probst C, Frunzke J, Nöh K, Wiechert W, Kohlheyer D (2013)PUB
Automated High-Throughput Time-Lapse Microscopy of Bacteria Microcolonies in Parallelized Monolayer Growth Chambers.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912607Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)PUB
SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the Nikon Symposium on Advanced Imaging in Cell- and Microbiology Technology and Applications, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912614Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)PUB
Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912619Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)PUB
Femtoliter chemostat for long-term bacteria growth and production analysis on single cell level.
Presented at the 2nd International Conference Implementation of Microreactor Technology in Biotechnology, Cavtat, Croatia. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912621Grünberger A, Mustafi N, Probst C, Frunzke J, Wiechert W, Kohlheyer D (2013)PUB
Towards High-Throughput Microbial Single Cell Analysis In Picoliter Bioreactors.
Presented at the 9th European Congress of Chemical Engineering, Den Haag, The Netherlands. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912626Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)PUB
Femtoliter chemostat for long-term bacteria growth and production analysis on single cell level.
Presented at the Single Cell Analysis Europe 2013, Barcelona, Spain. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912809Frunzke J, Mahr R, Grünberger A, Mustafi N, Kohlheyer D (2013)PUB
Microbial Metabolite Production – Live in Concert.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912828Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)PUB
Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures?
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912830Probst C, Grünberger A, Krämer C, Wiechert W, Kohlheyer D (2013)PUB
Microfluidic single-cell analysis in dynamic environments.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912835Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)PUB
Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912826Helfrich S, Azzouzi CE, Grünberger A, Wiechert W, Nöh K (2013)PUB
Exploration and Analysis of cell population development. Customizable interactive lineage trees.
Presented at the Jülich Biotech Day, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912833Nanda AM, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)PUB
Single-cell dynamics of the SOS response in Corynebacterium glutamicum.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912600Probst C, Grünberger A, Wiechert W, Kohlheyer D (2013)PUB | DOI | WoS | PubMed | Europe PMC
Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes.
Journal of microbiological methods 95(3): 470-476. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912612Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)PUB
SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912617Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)PUB
Continuous viability fluorescent staining of growing Corynebacterium glutamicum colonies without sample preparation in an automated microfluidic measurement system.
Presented at the How Deas Is Dead III Conference, Berlin, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912624Grünberger A, Mustafi N, Probst C, Frunzke J, Wiechert W, Kohlheyer D (2013)PUB
High-throughput Microbial Single Cell analysis in Picoliter Bioreactors.
Presented at the VAAM-Tagung 2013, Bremen, Germany. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912631Grünberger A, van Ooyen J, Paczia N, Rohe P, Schendzielorz G, Eggeling L, Wiechert W, Kohlheyer D, Noack S (2013)PUB | DOI | WoS | PubMed | Europe PMC
Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments.
Biotechnology and bioengineering 110(1): 220-228. -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912747Scholz KE, Okrob D, Kopka B, Grünberger A, Pohl M, Jaeger K-E, Krauss U (2012)PUB | DOI | WoS | PubMed | Europe PMC
Synthesis of Chiral Cyanohydrins by Recombinant Escherichia coli Cells in a Micro-Aqueous Reaction System.
Applied and Environmental Microbiology 78(14): 5025-5027. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912635Binder S, Schendzielorz G, Kohlheyer D, Grünberger A, Wiechert W, Bott M, Eggeling L (2012)PUB
Metabolite sensors for single-cell isolation of producing bacteria.
Presented at the Metabolic Engineering IX, Biarritz, France. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912642Grünberger A, Frank P, Probst C, Wiechert W, Kohlheyer D (2012)PUB
Single Cell Microfluidics: From Fabrication to Application.
Presented at the Jülich Biotech Day, Jülich, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912647Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2012)PUB
Semi-Automated Evaluation of Microbial Observables from High-Throughput Time-lapse Microscopy.
Presented at the German Conference on Bioinformatics 2012, Jena (Germany). -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912767Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)PUB
Fermentation at Picoliter Scale: Microfluidics for single cell analysis of prokaryotic production strains.
Presented at the Achema 2012, Frankfurt, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912837Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)PUB
Screening of Escherichia coli on single-cell level by hyphenating microfluidic picoliter fermentation and optical tweezers.
Presented at the 3rd European Conference on Microfluidics, Heidelberg, Germany. -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912728Grünberger A, Paczia N, Probst C, Schendzielorz G, Eggeling L, Noack S, Wiechert W, Kohlheyer D (2012)PUB | PDF | DOI | WoS | PubMed | Europe PMC
A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level.
Lab on a Chip 12(11): 2060-2068. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912776Grünberger A, Probst. C, Frank P, Wiechert W, Kohlheyer D (2012)PUB
Single Cell Analysis of Industrially Relevant Bacterial Strains in Picoliter Environments.
Presented at the EMBL Conference – Microfluidics 2012, Heidelberg, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912839Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)PUB
Phenotypic Sorting and Analysis of Bacteria Production Strains using Optical Tweezers and Microfluidics.
Presented at the EMBL Conference – Microfluidics 2012, Heidelberg, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912841Nanda AM, Grünberger A, Heyer A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2012)PUB
Dynamics of the SOS response in single cells of Corynebacterium glutamicum.
Presented at the 2nd Molecular Microbiology Meeting Würzburg, Würzburg, Germany. -
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2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912646Grünberger A, Helfrich S, Probst C, Nöh K, Wiechert W, Kohlheyer D (2012)PUB
Industrial Biotechnology meets Microfluidics - Disposable high-throughput single cell analysis device for industrially relevant bacterial strains.
In: Proceedings - µFLU-12. Colin S (Ed); Publications S.H.F., Paris: SHF. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912633Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)PUB
Picoliter bioreactors for growth heterogeneity studies of industrially relevant bacteria on single cell level.
Presented at the 2nd BioProScale Symposium: Inhomogeneities in large-scale bioprocesses: System biology and process dynamics, Berlin, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912638Mustafi N, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Bott M, Frunzke J (2012)PUB
A biosensor for the intracellular detection of L-methionine and branched-chain amino acids - Monitoring of amino acid production at the single cell level.
Presented at the 15th International Conference on Biotechnology, Istanbul, Turkey. -
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912645Kohlheyer D, Grünberger A, Probst C, Frank P, Wiechert W (2012)PUB
Catch it and batch it: picoliter fermentation at the single cell level.
Presented at the International Workshop on New and Synthetic Bioproduction Systems, Hamburg-Harburg, Germany. -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912746Mustafi N, Grünberger A, Kohlheyer D, Bott M, Frunzke J (2012)PUB | DOI | WoS | PubMed | Europe PMC
The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acids.
Metabolic Engineering 14(4): 449-457. -
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912758Grünberger A, Probst C, Binder S, Ziaee R, Eggeling L, Wiechert W, Kohlheyer D (2012)PUB
Single Cell Trapping and Analysis for Prokaryotic Production Strains in Sub-µm Fluidic Structures.
In: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011 (MiroTAS 2011). Landers J (Ed); Red Hook, NY: Curran. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912777Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)PUB
Towards high-throughput single cell growth optimization and production analysis using picoliter bioreactors.
Presented at the Metabolic Engineering IX 2012, Biarritz, France. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912838Frank P, Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)PUB
“Catch it and Batch it”- Microfluidics single cell batch cultivation utilizing picoliter bioreactors.
Presented at the ProcessNet- Jahrestagung 2012 und 30. DECHEMA Jahrestagung der Biotechnologen, Karlsruhe, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912840Nanda AM, Grünberger A, Heyer A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2012)PUB
Dynamics of the SOS response in single cells of Corynebacterium glutamicum.
Presented at the Microbial Stress: from Molecules to System, Belgirate (VB)/Maggiore Lake, Italy. -
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912643Grünberger A, Helfrich S, Probst C, Wiechert W, Nöh K, Kohlheyer D (2012)PUB
High-Throughput lineage tree investigations of bacteria microcolonies using arrays of monolayer growth chambers.
In: Proceedings of The Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2012). San Diego, California: CBMS. -
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912778Grünberger A, Probst C, Wiechert W, Kohlheyer D (2011)PUB
Single Cell Trapping and Analysis for Prokaryotic Production Strains in Sub -µm Fluidic Structures.
Presented at the NanoBioTech-Montreux 2011, Montreux, Switzerland. -
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912843Scholz KE, Okrob D, Kopka B, Grünberger A, Pohl M, Jaeger KE, Krauss U (2011)PUB
Fluorescence reporters for the analysis of whole cell biocatalysts in non-conventional media.
Presented at the Biotrans 2011, Giardini Naxos (Messina), Italy. -
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912811Kohlheyer D, Grünberger A, Probst C, Wiechert W (2011)PUB
Sub-µm Fluidic Structures for Single Cell Trapping and Analysis of Prokaryotic Production Strains.
Presented at the 21st Annual conference of the German Society for Cytometry, Bonn, Germany. -
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912842Mustafi N, Grünberger A, Kohlheyer D, Bott M, Frunzke J (2011)PUB
A biosensor for the intracellular detection of L-methionine and branched-chain amino acids.
Presented at the 5th International Conference on Analysis of Microbial Cells at the Single Cell Level, Caryy-Le-Rouet, France. -
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912768Grünberger A, Probst C, Wiechert W, Kohlheyer D (2011)PUB
A continuous picoliter bioreactor for heterogeneity studies of bacteria microcolonies.
Presented at the NanoBioTech-Montreux 2011, Montreux, Switzerland. -
2010 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912812Blanko MA, Grünberger A, Sahin E, Roberts CJ (2010)PUB
Protein Interactions from Kirwood-Buff Analysis of Light Scattering and Coarse-Grained Molecular Models.
Presented at the AIChE Annual Meeting, Salt Lake City (UT), USA. -
2009 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912813Grünberger A, Stephens E, Hankamer B (2009)PUB
Media optimization for the microalgae Chamydomonas reinhardtii Stm6 using statistical design.
Presented at the IMB Summer Symposium: A systems Biology approach to biofuel production: From light capture to biodiesel production, Brisbane, Australia.