Alexander Grünberger

alexander.gruenberger@uni-bielefeld.de
PEVZ-ID
94700790

233 Publikationen

Alle markieren

  • [233]
    2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2986983
    Blöbaum, L.; Torello Pianale, L.; Olsson, L.; Grünberger, A. (2024): Quantifying microbial robustness in dynamic environments using microfluidic single-cell cultivation Microbial Cell Factories ,23:(1):44
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [232]
    2023 | Preprint | Veröffentlicht | PUB-ID: 2985556
    Nieto, C.; Täuber, S.; Blöbaum, L.; Vahdat, Z.; Grünberger, A.; Singh, A. (2023): Coupling Cell Size Regulation and Proliferation Dynamics of Reveals Cell Division Based on Surface Area bioRxiv
    PUB | DOI | PubMed | Europe PMC
     
  • [231]
    2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2968932 OA
    Steinhoff, H.; Finger, M.; Osthege, M.; Golze, C.; Schito, S.; Noack, S.; Buchs, J.; Grünberger, A. (2023): Experimental ks estimation: A comparison of methods for Corynebacterium glutamicum from lab to microfluidic scale. Biotechnology and Bioengineering,120:(5): 1167-1449.
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  • [230]
    2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2982187
    Blöbaum, L.; Täuber, S.; Grünberger, A. (2023): Protocol to perform dynamic microfluidic single-cell cultivation of C.glutamicum STAR Protocols ,4:(3):102436
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [229]
    2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2969695
    Täuber, S.; Grünberger, A. (2023): Microfluidic single-cell scale-down systems: introduction, application, and future challenges Current Opinion in Biotechnology,81:102915
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  • [228]
    2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2964098 OA
    Täuber, S.; Blöbaum, L.; Steier, V.; Oldiges, M.; Grünberger, A. (2022): Microfluidic single-cell scale-down bioreactors: A proof-of-concept for the growth of Corynebacterium glutamicum at oscillating pH values Biotechnology and Bioengineering,119:(11): 3194-3209.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC | Preprint
     
  • [227]
    2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2963033 OA
    Smaluch, K.; Wollenhaupt, B.; Steinhoff, H.; Kolhheyer, D.; Grünberger, A.; Dusny, C. (2022): Assessing the growth kinetics and stoichiometry of Escherichia coli at the single-cell level Engineering in Life Sciences
    PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
     
  • [226]
    2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2962620 OA
    Karsten, L.; Gött-Zink, L.; Schmitz, J.; Hoffrogge, R.; Grünberger, A.; Kottke, T.; Müller, K. (2022): Genetically Encoded Ratiometric pH Sensors for the Measurement of Intra- and Extracellular pH and Internalization Rates Biosensors,12:(5):271
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [225]
    2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2967671
    Blöbaum, L.; Haringa, C.; Grünberger, A. (2022): Microbial lifelines in bioprocesses: From concept to application Biotechnology Advances,62
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  • [224]
    2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2963556 OA
    Romanova, N.; Schmitz, J.; Strakeljahn, M.; Grünberger, A.; Bahnemann, J.; Noll, T. (2022): Single-Cell Analysis of CHO Cells Reveals Clonal Heterogeneity in Hyperosmolality-Induced Stress Response Cells,11:(11):1763
    PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
     
  • [223]
    2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2964097
    Ho, P.; Täuber, S.; Stute, B.; Grünberger, A.; von Lieres, E. (2022): Microfluidic Reproduction of Dynamic Bioreactor Environment Based on Computational Lifelines Frontiers in Chemical Engineering,4:826485
    PUB | DOI
     
  • [222]
    2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2962029
    Bahnemann, J.; Grünberger, A. (2022): Microfluidics in Biotechnology: Overview and Status Quo Advances in Biochemical Engineering, Biotechnology , 1-16.
    PUB | DOI | PubMed | Europe PMC
     
  • [221]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2956409 OA
    Schmitz, J.; Höving, A. L.; Schmidt, K. E.; Greiner, J.; Knabbe, C.; Kaltschmidt, B.; Grünberger, A.; Kaltschmidt, C. (2021): Human Blood Serum Induces p38-MAPK- and Hsp27-Dependent Migration Dynamics of Adult Human Cardiac Stem Cells: Single-Cell Analysis via a Microfluidic-Based Cultivation Platform Biology,10:(8):708
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  • [220]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2956806 OA
    Hermann, K. M.; Grünberger, A.; Patel, A. (2021): Formalin-casein enhances water absorbency of calcium alginate beads and activity of encapsulated Metarhizium brunneum and Saccharomyces cerevisiae World Journal of Microbiology and Biotechnology,37:(9):156
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  • [219]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2967242
    Dietsch, R.; Jakobs-Schoenwandt, D.; Grünberger, A.; Patel, A. (2021): Desiccation-tolerant fungal blastospores: From production to application Current Research in Biotechnology,3: 323-339.
    PUB | DOI | WoS
     
  • [218]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2957323 OA
    Täuber, S.; Blöbaum, L.; Wendisch, V. F.; Grünberger, A. (2021): Growth response and recovery of Corynebacterium glutamicum colonies on single-cell level upon defined pH stress pulses Frontiers in Microbiology,12: 711893.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC | Preprint
     
  • [217]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2959820 OA
    Täuber, S.; Schmitz, J.; Blöbaum, L.; Fante, N.; Steinhoff, H.; Grünberger, A. (2021): How to Perform a Microfluidic Cultivation Experiment—A Guideline to Success Biosensors,11:(12):485
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  • [216]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2955090 OA
    Schmitz, J.; Hertel, O.; Yermakov, B.; Noll, T.; Grünberger, A. (2021): Growth and eGFP-production of CHO-K1 suspension cells cultivated from single-cell to laboratory scale Frontiers in Bioengineering and Biotechnology,9:716343
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  • [215]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2964708 OA
    Blöbaum, L.; Täuber, S.; Grünberger, A. (2021): Ein Wechselbad für Mikroben: Wachsen unter dynamischen Umweltbedingungen BIOspektrum,27:(5): 491-493.
    PUB | PDF | DOI
     
  • [214]
    2021 | Zeitschriftenaufsatz | Im Druck | PUB-ID: 2957505
    Blombach, B.; Grünberger, A.; Centler, F.; Wierckx, N.; Schmid, J. (In Press): Exploiting unconventional prokaryotic hosts for industrial biotechnology Trends in biotechnology
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  • [213]
    2021 | Zeitschriftenaufsatz | Angenommen | PUB-ID: 2955245
    Stallmann, D.; Göpfert, J. P.; Schmitz, J.; Grünberger, A.; Hammer, B. (Accepted): Towards an automatic analysis of CHO-K1 suspension growth in microfluidic single-cell cultivation Bioinformatics
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [212]
    2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2951549
    Schlembach, I.; Grünberger, A.; Rosenbaum, M. A.; Regestein, L. (2021): Measurement Techniques to Resolve and Control Population Dynamics of Mixed-Culture Processes. Trends in Biotechnology
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  • [211]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2957513
    Lenz, P.; Hilgers, F.; Burmeister, A.; Zimmermann, L.; Volkenborn, K.; Grünberger, A.; Kohlheyer, D.; Drepper, T.; Jaeger, K. - E.; Knapp, A. (2021): The iSplit GFP assay detects intracellular recombinant proteins in Bacillus subtilis Microbial cell factories,20:(1):174
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  • [210]
    2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2955524
    Burmeister, A.; Akhtar, Q.; Hollmann, L.; Tenhaef, N.; Hilgers, F.; Hogenkamp, F.; Sokolowsky, S.; Marienhagen, J.; Noack, S.; Kohlheyer, D.; Grünberger, A. (2021): (Optochemical) Control of Synthetic Microbial Coculture Interactions on a Microcolony Level ACS synthetic biology
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  • [209]
    2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2955913
    Nguyen, T. M.; Telek, S.; Zicler, A.; Martinez, J. A.; Zacchetti, B.; Kopp, J.; Slouka, C.; Herwig, C.; Grünberger, A.; Delvigne, F. (2021): Reducing phenotypic instabilities of a microbial population during continuous cultivation based on cell switching dynamics Biotechnology and bioengineering
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  • [208]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949089 OA
    Schmitz, J.; Täuber, S.; Westerwalbesloh, C.; von Lieres, E.; Noll, T.; Grünberger, A. (2021): Development and application of a cultivation platform for mammalian suspension cell lines with single-cell resolution Biotechnology and Bioengineering,118:(2): 992-1005.
    PUB | Dateien verfügbar | DOI | WoS | PubMed | Europe PMC | Preprint
     
  • [207]
    2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2951151
    Winkler, S.; Grünberger, A.; Bahnemann, J. (2021): Microfluidics in Biotechnology: Quo Vadis Advances in biochemical engineering/biotechnology, 1-26.
    PUB | DOI | PubMed | Europe PMC
     
  • [206]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2946333 OA
    Della Corte, D.; van Beek, H. L.; Syberg, F.; Schallmey, M.; Tobola, F.; Cormann, K. U.; Schlicker, C.; Baumann, P. T.; Krumbach, K.; Sokolowsky, S.; Morris, C. J.; Grünberger, A.; Hofmann, E.; Schroder, G. F.; Marienhagen, J. (2020): Engineering and application of a biosensor with focused ligand specificity Nature communications,11:(1):4851
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  • [205]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2948721 OA
    Ortseifen, V.; Viefhues, M.; Wobbe, L.; Grünberger, A. (2020): Microfluidics for Biotechnology: Bridging Gaps to Foster Microfluidic Applications Frontiers in Bioengineering and Biotechnology,8:589074
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  • [204]
    2020 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2948408
    Täuber, S.; Golze, C.; Ho, P.; von Lieres, E.; Grünberger, A. (2020): dMSCC: a microfluidic platform for microbial single-cell cultivation of Corynebacterium glutamicum under dynamic environmental medium conditions Lab on a chip
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [203]
    2020 | Preprint | Veröffentlicht | PUB-ID: 2944674
    Täuber, S.; Golze, C.; Ho, P.; von Lieres, E.; Grünberger, A. (2020): dMSCC: A microfluidic platform for microbial single-cell cultivation under dynamic environmental medium conditions bioRxiv
    PUB | DOI | Preprint
     
  • [202]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2944673 OA
    Täuber, S.; Dormeyer, M.; Commichau, F. M.; Grünberger, A. (2020): Visualisierung von Mutationen auf Einzelzellebene BIOspektrum,26:(4): 388-390.
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  • [201]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2941821 OA
    Täuber, S.; Lieres, E.; Grünberger, A. (2020): Dynamic Environmental Control in Microfluidic Single‐Cell Cultivations: From Concepts to Applications Small,16:(16):1906670
    PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
     
  • [200]
    2020 | Zeitschriftenaufsatz | Im Druck | PUB-ID: 2939030
    Burmeister, A.; Grünberger, A. (In Press): Microfluidic cultivation and analysis tools for interaction studies of microbial co-cultures. Current opinion in biotechnology,62: 106-115.
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  • [199]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2937575 OA
    Hilgers, F.; Bitzenhofer, N. L.; Ackermann, Y.; Burmeister, A.; Grünberger, A.; Jaeger, K. - E.; Drepper, T. (2019): Genetically Encoded Photosensitizers as Light-Triggered Antimicrobial Agents. International journal of molecular sciences,20:(18):4608
    PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
     
  • [198]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2936034
    Lindemann, D.; Westerwalbesloh, C.; Kohlheyer, D.; Grünberger, A.; von Lieres, E. (2019): Microbial single-cell growth response at defined carbon limiting conditions RSC ADVANCES,9:(25): 14040-14050.
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  • [197]
    2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2935887
    Sassi, H.; Nguyen, T. M.; Telek, S.; Gosset, G.; Grünberger, A.; Delvigne, F. (2019): Segregostat: a novel concept to control phenotypic diversification dynamics on the example of Gram-negative bacteria. Microbial biotechnology,12:(5): 1064-1075.
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  • [196]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935495
    Ho, P.; Westerwalbesloh, C.; Kaganovitch, E.; Grünberger, A.; Neubauer, P.; Kohlheyer, D.; Lieres, E. von (2019): Reproduction of Large-Scale Bioreactor Conditions on Microfluidic Chips. Microorganisms,7:(4):105
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  • [195]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2937237
    Sachs, C. C.; Koepff, J.; Wiechert, W.; Grünberger, A.; Noh, K. (2019): mycelyso - high-throughput analysis of Streptomyces mycelium live cell imaging data BMC bioinformatics,20:(1):452
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  • [194]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2934065
    Jager, V. D.; Kloss, R.; Grünberger, A.; Seide, S.; Hahn, D.; Karmainski, T.; Piqueray, M.; Embruch, J.; Longerich, S.; Mackfeld, U.; Jaeger, K. - E.; Wiechert, W.; Pohl, M.; Krauss, U. (2019): Tailoring the properties of (catalytically)-active inclusion bodies. Microbial cell factories,18:(1):33
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [193]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2939585
    Dusny, C.; Grünberger, A. (2019): Microfluidic single-cell analysis in biotechnology: from monitoring towards understanding. Current opinion in biotechnology,63: 26-33.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [192]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2937529
    Schmitz, J.; Grünberger, A. (2019): Ich sehe 'was, was du nicht siehst LABO,51:(9): 30-33.
    PUB
     
  • [191]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935496
    Westerwalbesloh, C.; Brehl, C.; Weber, S.; Probst, C.; Widzgowski, J.; Grünberger, A.; Pfaff, C.; Nedbal, L.; Kohlheyer, D. (2019): A microfluidic photobioreactor for simultaneous observation and cultivation of single microalgal cells or cell aggregates. PloS one,14:(4):e0216093
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  • [190]
    2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2933358
    Schmitz, J.; Noll, T.; Grünberger, A. (2019): Heterogeneity Studies of Mammalian Cells for Bioproduction. From Tools to Application Trends in Biotechnology,37:(6): 645-660.
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  • [189]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935584
    Theorell, A.; Seiffarth, J.; Grünberger, A.; Noeh, K. (2019): When a single lineage is not enough: Uncertainty-Aware Tracking for spatio-temporal live-cell image analysis BIOINFORMATICS,35:(7): 1221-1228.
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  • [188]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932955
    Burmeister, A.; Hilgers, F.; Langner, A.; Westerwalbesloh, C.; Kerkhoff, Y.; Tenhaef, N.; Drepper, T.; Kohlheyer, D.; von Lieres, E.; Noack, S.; Grünberger, A. (2019): A microfluidic co-cultivation platform to investigate microbial interactions at defined microenvironments LAB ON A CHIP,19:(1): 98-110.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [187]
    2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920273
    Kloss, R.; Limberg, M. H.; Mackfeld, U.; Hahn, D.; Grünberger, A.; Jaeger, V. D.; Krauss, U.; Oldiges, M.; Pohl, M. (2018): Catalytically active inclusion bodies of L-lysine decarboxylase from E. coli for 1,5-diaminopentane production SCIENTIFIC REPORTS,8:(1):5856
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  • [186]
    2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932416
    Kampf, J.; Gerwig, J.; Kruse, K.; Cleverley, R.; Dormeyer, M.; Grünberger, A.; Kohlheyer, D.; Commichau, F. M.; Lewis, R. J.; Stuelke, J. (2018): Selective Pressure for Biofilm Formation in Bacillus subtilis: Differential Effect of Mutations in the Master Regulator SinR on Bistability mBio,9:(5):e01464-18
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [185]
    2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920685
    Mosheiff, N.; Martins, B. M. C.; Pearl-Mizrahi, S.; Grünberger, A.; Helfrich, S.; Mihalcescu, I.; Kohlheyer, D.; Locke, J. C. W.; Glass, L.; Balaban, N. Q. (2018): Inheritance of Cell-Cycle Duration in the Presence of Periodic Forcing PHYSICAL REVIEW X,8:(2):15
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  • [184]
    2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932764 OA
    Koepff, J.; Sachs, C. C.; Wiechert, W.; Kohlheyer, D.; Noeh, K.; Oldiges, M.; Grünberger, A. (2018): Germination and Growth Analysis of Streptomyces lividans at the Single-Cell Level Under Varying Medium Compositions FRONTIERS IN MICROBIOLOGY,9:2680
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  • [183]
    2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2930515
    Hage-Huelsmann, J.; Grünberger, A.; Thies, S.; Santiago-Schuebel, B.; Klein, A. S.; Pietruszka, J.; Binder, D.; Hilgers, F.; Domroese, A.; Drepper, T.; Kohlheyer, D.; Jaeger, K. - E.; Loeschcke, A. (2018): Natural biocide cocktails: Combinatorial antibiotic effects of prodigiosin and biosurfactants PLOS ONE,13:(7):e0200940
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  • [182]
    2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2919078
    Hornung, R.; Grünberger, A.; Westerwalbesloh, C.; Kohlheyer, D.; Gompper, G.; Elgeti, J. (2018): Quantitative modelling of nutrient-limited growth of bacterial colonies in microfluidic cultivation JOURNAL OF THE ROYAL SOCIETY INTERFACE,15:(139):11
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  • [181]
    2018 | Konferenzbeitrag | PUB-ID: 2933363
    Schmitz, J.; Noll, T.; Grünberger, A. (2018): Towards Microfluidic Single-Cell Cultivation of Mammalian Cell Lines.
    PUB
     
  • [180]
    2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933359
    Schmitz, J.; Kerkhoff, Y.; Noll, T.; Kohlheyer, D.; Grünberger, A. (2018): Towards dynamic single-cell cultivation systems for industrially relevant mammalian cell lines.
    PUB
     
  • [179]
    2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933362
    Schmitz, J.; Kerkhoff, Y.; Noll, T.; Grünberger, A. (2018): Dynamic microfluidical single-cell cultivation of mammalian cell lines. From experiment to analysis.
    PUB
     
  • [178]
    2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932765
    Kloss, R.; Karmainski, T.; Jaeger, V. D.; Hahn, D.; Grünberger, A.; Baumgart, M.; Krauss, U.; Jaeger, K. - E.; Wiechert, W.; Pohl, M. (2018): Tailor-made catalytically active inclusion bodies for different applications in biocatalysis CATALYSIS SCIENCE & TECHNOLOGY,8:(22): 5816-5826.
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  • [177]
    2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2931505
    Jaeger, V. D.; Lamm, R.; Kloss, R.; Kaganovitch, E.; Grünberger, A.; Pohl, M.; Buechs, J.; Jaeger, K. - E.; Krauss, U. (2018): A Synthetic Reaction Cascade Implemented by Colocalization of Two Proteins within Catalytically Active Inclusion Bodies ACS SYNTHETIC BIOLOGY,7:(9): 2282-2295.
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  • [176]
    2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2919063
    Dormeyer, M.; Lentes, S.; Ballin, P.; Wilkens, M.; Klumpp, S.; Kohlheyer, D.; Stannek, L.; Grünberger, A.; Commichau, F. M. (2018): Visualization of tandem repeat mutagenesis in Bacillus subtilis DNA REPAIR,63: 10-15.
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  • [175]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912521
    Grünberger, A.; Schöler, K.; Probst, C.; Kornfeld, G.; Hardiman, T.; Wiechert, W.; Kohlheyer, D.; Noack, S. (2017): Real-time monitoring of fungal growth and morphogenesis at single-cell resolution Engineering in life sciences,17:(1): 86–92.
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  • [174]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912738
    Westerwalbesloh, C.; Grünberger, A.; Wiechert, W.; Kohlheyer, D.; von Lieres, E. (2017): Coarse-graining bacteria colonies for modelling critical solute distributions in picolitre bioreactors for bacterial studies on single-cell level Microbial Biotechnology,10:(4): 845-857.
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  • [173]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916519
    Binder, D.; Drepper, T.; Jaeger, K. - E.; Delvigne, F.; Wiechert, W.; Kohlheyer, D.; Grünberger, A. (2017): Homogenizing bacterial cell factories: Analysis and engineering of phenotypic heterogeneity METABOLIC ENGINEERING,42: 145-156.
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  • [172]
    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912503
    Rudat, A.; Wiechert, W.; Kohlheyer, D.; Grünberger, A. (2017): Picoliter bioreactors for microbial consortia: From proof of concept to first application.
    PUB
     
  • [171]
    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912508
    Burmeister, A.; Bitzenhofer, N. L.; Grünberger, A.; Binder, D.; Drepper, T.; Wiechert, W.; Kohlheyer, D. (2017): Microfluidic heterogeneity analysis of fluorescence-based gene expression of industrially relevant production strains on single-cell level.
    PUB
     
  • [170]
    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912759
    Grünberger, A. (2017): Microfluidic Single-Cell Cultivation: A key for next generation bioprocess development?
    PUB
     
  • [169]
    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912771
    Rudat, A.; Noack, S.; Wiechert, W.; Kohlheyer, D.; Grünberger, A. (2017): Microfluidic single-cell (co-)cultivation: Exploring the next dimension.
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    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912502
    Jäger, V. D.; Longerich, S.; Dietrich, M.; Kloss, R.; Grünberger, A.; Pohl, M.; Jaeger, K. - E.; Krauss, U. (2017): Functionally-active protein aggregates - towards the realization of an enzyme cascade in catalytically-active inclusion bodies.
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    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912505
    Sachs, C. C.; Koepff, J.; Kohlheyer, D.; Wiechert, W.; Oldiges, M.; Nöh, K.; Grünberger, A. (2017): Microfluidic single-cell cultivation of S. lividans: Uncovering heterogeneity in filamentous growth.
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    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912507
    Rudat, A.; Wiechert, W.; Kohlheyer, D.; Grünberger, A. (2017): Spatiotemporal analysis of synthetic microbial communities at the single-cell level in microfluidic interaction compartments.
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    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912501
    Kloss, R.; Limberg, M.; Jäger, V. D.; Mackfeld, U.; Karmainski, T.; Grünberger, A.; Krauss, U.; Pohl, M. (2017): Catalytically active inclusion bodies. A novel carrier-free Enzyme Immobilisation method.
    PUB
     
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    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912506
    Sachs, C. C.; Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D.; Nöh, K. (2017): Integrated High-Throughput Platform for Microfluidic Live-Cell Analysis with Feed-Back Eyperimentation.
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    2017 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912518
    Kaganovitch, E.; Krischer, M.; Probst, C.; Grünberger, A.; Zunic, E.; Freier, C.; Wiechert, W.; Kohlheyer, D. (2017): Microfluidic device for control and sensing of dynamic oxygen levels during cell cultivation. In: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016). Red Hook, NY: Curran Associates, Inc. S. 355-356.
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    2017 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2912520
    Ladner, T.; Grünberger, A.; Probst, C.; Kohlheyer, D.; Büchs, J.; Delvigne, F. (2017): Application of Mini- and Micro-Bioreactors for Microbial Bioprocesses. In: Christian Larroche; Maria Ángeles Sanromán; Guocheng Du; Ashok Pandey (Hrsg.): Current Developments in Biotechnology and Bioengineering. Amsterdam: Elsevier. S. 433-461.
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    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912737
    Delvigne, F.; Baert, J.; Sassi, H.; Fickers, P.; Grünberger, A.; Dusny, C. (2017): Taking control over microbial populations: Current approaches for exploiting biological noise in bioprocesses Biotechnology Journal,12:(7):1600549
    PUB | DOI | WoS | PubMed | Europe PMC
     
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    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912504
    Westerwalbesloh, C.; Grünberger, A.; Wiechert, W.; Kohlheyer, D.; von Lieres, E. (2017): Models for Developing and Optimizing Microscale Bacteria Cultivation.
    PUB
     
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    2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912509
    Rudat, A.; Wiechert, W.; Kohlheyer, D.; Grünberger, A. (2017): Microfluidic cultivation chamber for the investigation of synthetic microbial co-cultures on single-cell level: From the development to first application.
    PUB
     
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    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912514 OA
    Binder, D.; Probst, C.; Grünberger, A.; Hilgers, F.; Loeschcke, A.; Jaeger, K. - E.; Kohlheyer, D.; Drepper, T. (2016): Comparative Single-Cell Analysis of Different E. coli Expression Systems during Microfluidic Cultivation PLoS one,11:(8):e0160711
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
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    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912522 OA
    Sachs, C. C.; Grünberger, A.; Helfrich, S.; Probst, C.; Wiechert, W.; Kohlheyer, D.; Nöh, K. (2016): Image-Based Single Cell Profiling: High-Throughput Processing of Mother Machine Experiments PLoS one,11:(9):e0163453
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
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    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912513
    Kusen, P. M.; Wandrey, G.; Probst, C.; Grünberger, A.; Holz, M.; Meyer zu Berstenhorst, S.; Kohlheyer, D.; Büchs, J.; Pietruszka, J. (2016): Optogenetic Regulation of Tunable Gene Expression in Yeast Using Photo-Labile Caged Methionine ACS chemical biology,11:(10): 2915-2922.
    PUB | DOI | WoS | PubMed | Europe PMC
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912527
    Grünberger, A. (2016): Microfluidic single-cell cultivation: Is small the new beautiful?
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912534
    Grünberger, A. (2016): Single-cell microfluidics for bioprocess development.
    PUB
     
  • [153]
    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912539
    Westerwalbesloh, C.; Grünberger, A.; Stute, B.; Weber, S.; Wiechert, W.; Kohlheyer, D.; von Lieres, E. (2016): Nutrient distribution in perfusion based picoliter bioreactors.
    PUB
     
  • [152]
    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912820
    Hage-Hülsmann, J.; Grünberger, A.; Thies, S.; Domröse, A.; Klein, A.; Binder, D.; Hilgers, F.; Kohlheyer, D.; Pietruszka, J.; Jaeger, K. - E.; Drepper, T.; Loeschcke, A. (2016): Combinatorial antibiotic effects of natural biocide cocktails.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912761
    Grünberger, A. (2016): Microfluidic single-cell bioreactors. Introduction, application and future perspectives.
    PUB
     
  • [150]
    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912803
    Binder, D.; Bier, C.; Grünberger, A.; Hilgers, F.; Loeschcke, A.; Kohlheyer, D.; Pietruszka, J.; Jaeger, K. E.; Drepper, T. (2016): Employing photocaged carbohydrates in light-controlled cell factories for synthetic bio(techno)logy and single cell applications.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912512
    Bier, C.; Binder, D.; Grünberger, A.; Drobietz, D.; Hage-Hülsmann, J.; Kohlheyer, D.; Löschcke, A.; Jaeger, K. - E.; Drepper, T.; Pietruszka, J. (2016): Sugar Based Caged Compounds for Biotechnological Synthetic Biological Applications.
    PUB
     
  • [148]
    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912524
    Brehl, C.; Grünberger, A.; Probst, C.; Pfaff, C.; Wiechert, W.; Behrendt, D.; Kohlheyer, D. (2016): Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environments.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912526
    Westerwalbesloh, C.; Grünberger, A.; Wiechert, W.; Kohlheyer, D.; von Lieres, E. (2016): Comparison of different cultivation chamber designs for microfluidic bioreactors Chemie Ingenieur Technik,88:(9): 1390.
    PUB | DOI
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912529
    Grünberger, A.; Steffens, I.; Binder, D.; Drepper, T.; Wiechert, W.; Kohlheyer, D. (2016): Microbial metabolic state diagrams: Using microfluidic single-cell cultivation to predict bacterial gene expresssion.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912531
    Westerwalbesloh, C.; Grünberger, A.; Kohlheyer, D.; von Lieres, E. (2016): Modeling inhomogeneities across cultivation chamber arrays in single-cell cultivation devices.
    PUB
     
  • [144]
    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912536
    Sachs, C. C.; Probst, C.; Grünberger, A.; Wiechert, W.; Frunzke, J.; Kohlheyer, D.; Nöh, K. (2016): An integrated platform for dynamic microfluidic experimentation with single-cell resolution.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912538
    Steffens, I.; Grünberger, A.; Binder, D.; Drepper, T.; Wiechert, W.; Kohlheyer, D. (2016): Bacterial phase diagrams. Analyzing and predicting cell-to-cell heterogeneity of microbial gene expression.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912540
    Grünberger, A.; Steffens, I.; Binder, D.; Drepper, T.; Wiechert, W.; Kohlheyer, D. (2016): Bacterial phase diagrams – Using engineering concepts to predict cell-to-cell heterogeneity of microbial gene expression.
    PUB
     
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    2016 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912552
    Probst, C.; Freier, C.; Mahr, R.; Grünberger, A.; Helfrich, S.; Wiechert, W.; Nöh, K.; Frunzke, J.; Kohlheyer, D. (2016): Closing the gap between microfluidic single-cell analysis and bioprocess development for microbial organisms. In: 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015). Red Hook, NY: Curran Associates, Inc. S. 537-539.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912525
    Burmeister, A.; Bitzenhofer, N. L.; Grünberger, A.; Binder, D.; Drepper, T.; Wiechert, W. (2016): Microfluidic heterogeneity analysis of fluorescence-based gene expression of industrially relevant production strains on single-cell level.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912532
    Westerwalbesloh, C.; Grünberger, A.; Stute, B.; Weber, S.; Kohlheyer, D.; von Lieres, E. (2016): Characterizing substrate availability within microfluidic tools employed for the analysis of genetically modified single cells.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912537
    Grünberger, A.; Wiechert, W.; Kohlheyer, D. (2016): Bioprocesses under magnification. Learning from single cells about large-scale processes.
    PUB
     
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    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912544
    Binder, D.; Bier, C.; Grünberger, A.; Drobietz, D.; Hage-Hülsmann, J.; rey, G.; Büchs, J.; Kohlheyer, D.; Loeschcke, A.; Wiechert, W.; Jaeger, K. - E.; Pietruszka, J.; Drepper, T. (2016): Photocaged Arabinose - A Novel Optogenetic Switch for Rapid and Gradual Control of Microbial Gene Expression ChemBioChem,17:(4): 296-299.
    PUB | DOI | WoS | PubMed | Europe PMC
     
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    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912739
    Li, S.; Jendresen, C. B.; Grünberger, A.; Ronda, C.; Jensen, S. I.; Noack, S.; Nielsen, A. T. (2016): Enhanced protein and biochemical production using CRISPRi-based growth switches Metabolic Engineering,38: 274-284.
    PUB | DOI | WoS | PubMed | Europe PMC
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912760
    Grünberger, A. (2016): Picoliter bioreactors for microbial consortia: A novel concept to investigate microbial interactions at the single-cell level.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912772
    Grünberger, A.; Sachs, C.; Kohlheyer, D.; Wiechert, W.; Nöh, K. (2016): Spatio-temporal analysis of bacterial populations at single-cell level.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912511
    Bier, C.; Binder, D.; Grünberger, A.; Drobietz, D.; Kohlheyer, D.; Löschcke, A.; Jaeger, K. - E.; Drepper, T.; Pietruszka, J. (2016): Photocaged Carbohydrates: Versatile Tools for Biotechnological Applications.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912523
    Brehl, C.; Grünberger, A.; Probst, C.; Pfaff, C.; Wiechert, W.; Behrendt, D.; Kohlheyer, D. (2016): Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environments.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912530
    Kaganovitch, E.; Probst, C.; Westerwalbesloh, C.; Grünberger, A.; Wiechert, W.; Kohlheyer, D. (2016): Single-cell analysis of E. coli in microfluidic batch reactors.
    PUB
     
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    2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912535
    Grünberger, A.; Steffens, I.; Binder, D.; Drepper, T.; Wiechert, W.; Kohlheyer, D. (2016): Bacterial phase diagrams: A novel concept to predict and control bacterial gene expression.
    PUB
     
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    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904866
    Binder, D.; Frohwitter, J.; Mahr, R.; Bier, C.; Grünberger, A.; Loeschcke, A.; Peters-Wendisch, P.; Kohlheyer, D.; Pietruszka, J.; Frunzke, J.; Jaeger, K. - E.; Wendisch, V. F.; Drepper, T. (2016): Light-controlled cell factories – Employing photocaged IPTG for light-mediated optimization of lac-based gene expression and (+)-valencene biosynthesis in Corynebacterium glutamicum Appl Environ Microbiol,82:(20): 6141-6149.
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    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912584
    Probst, C.; Grünberger, A.; Braun, N.; Helfrich, S.; Nöh, K.; Wiechert, W.; Kohlheyer, D. (2015): Rapid inoculation of single bacteria into parallel picoliter fermentation chambers Analytical methods,7:(1): 91-98.
    PUB | DOI | WoS
     
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    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912568
    Dusny, C.; Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D.; Schmid, A. (2015): Technical bias of microcultivation environments on single cell physiology Lab on a chip,15:(8): 1822-1834.
    PUB | DOI | WoS | PubMed | Europe PMC
     
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    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912550
    Grünberger, A.; Probst, C.; Helfrich, S.; Nanda, A.; Stute, B.; Wiechert, W.; von Lieres, E.; Nöh, K.; Frunzke, J.; Kohlheyer, D. (2015): Spatiotemporal microbial single-cell analysis using a high-throughput microfluidics cultivation platform Cytometry / A,87:(12): 1101–1115.
    PUB | DOI | WoS | PubMed | Europe PMC
     
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    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912554 OA
    Krämer, C. E. M.; Singh, A.; Helfrich, S.; Grünberger, A.; Wiechert, W.; Nöh, K.; Kohlheyer, D. (2015): Non-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl Ester PLoS one,10:(10):e0141768
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
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    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912555
    Helfrich, S.; Azzouzi, C. E.; Probst, C.; Seiffarth, J.; Grünberger, A.; Wiechert, W.; Kohlheyer, D.; Nöh, K. (2015): Vizardous: interactive analysis of microbial populations with single cell resolution Bioinformatics,31:(23): 3875-3877.:btv468
    PUB | DOI | WoS | PubMed | Europe PMC
     
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    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912557 OA
    Westerwalbesloh, C.; Grünberger, A.; Stute, B.; Weber, S.; Wiechert, W.; Kohlheyer, D.; von Lieres, E. (2015): Modeling and CFD Simulation of nutrient Distribution in picoliter bioreactors for bacterial growth studies on single-cell level Lab on a chip,15:(21): 4177-4186.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
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    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912541
    Binder, D.; Bier, C.; Grünberger, A.; Loeschcke, A.; Kohlheyer, D.; Pietruszka, J.; Jaeger, K. - E.; Drepper, T. (2015): Light-controlled cell factories - Employing optogenetic plug-and-play expression modules based on photocaged carbohydrates for synthetic bio(techno)logy and single cell applications.
    PUB
     
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    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912546
    Grünberger, A.; Wiechert, W.; Kohlheyer, D. (2015): Single-cell microfluidics: A key technology to understand life at environmental defined conditions.
    PUB
     
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    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912560
    Zunic, E.; Schechtel, A.; Probst, C.; Grünberger, A.; Freier, C.; Seibold, G.; Wiechert, W.; Kohlheyer, D. (2015): Dynamic environmental control in microfluidic devices for single-cell Analysis of biological production processes.
    PUB
     
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    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912565
    Grünberger, A.; Probst, C.; Frunzke, J.; Noack, S.; Wiechert, W.; Kohlheyer, D. (2015): Single-cell microfluidics meets applied biotechnology. From expectation to application.
    PUB
     
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    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912773
    Grünberger, A.; Probst, C.; Frunzke, J.; Noack, S.; Wiechert, W.; Kohlheyer, D. (2015): Single-cell microfluidics meets applied biotechnology. From expectation to application.
    PUB
     
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    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912545
    Loeschcke, A.; Thies, S.; Hage-Hülsmann, J.; Grünberger, A.; Binder, D.; Domröse, A.; Klein, A.; Kohlheyer, D.; Pietruszka, J.; Jaeger, K. - E.; Drepper, T. (2015): Heterologous production of antibacterial secondary metabolites from Serratia marcescens in Pseudomonas putida.
    PUB
     
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    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912548
    Bier, C.; Binder, D.; Grünberger, A.; Drobietz, D.; Hage-Hülsmann, J.; Kohlheyer, D.; Loeschke, A.; Jaeger, K. - E.; Drepper, T.; Pietruszka, J. (2015): Caged Compounds for Biotechnological and Synthetic Biological Applications.
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    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912562
    Grünberger, A. (2015): Einzelzell-Bioreaktoren - fast unsichtbar, aber nicht unscheinbar Biospektrum,21:(3): 353-353.
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    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912567
    Grünberger, A. (2015): Single-cell bioreactors: Improving the understanding of microbial metabolism.
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    2015 | Dissertation | Veröffentlicht | PUB-ID: 2912574 OA
    Grünberger, A. (2015): Single-Cell Analysis of Microbial Production Strains in Microfluidic Bioreactors. Jülich: RWTH Aachen.
    PUB | PDF
     
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    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912549
    Mahr, R.; Mustafi, N.; Grünberger, A.; Helfrich, S.; Nöh, K.; Kohlheyer, D.; Frunzke, J. (2015): Metabolite biosensors for single cell Analysis and the Evolution of production strains.
    PUB
     
  • [111]
    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912551
    Probst, C.; Grünberger, A.; Krämer, C.; Sachs, C. C.; Wiechert, W.; Baumgart, M.; Kohlheyer, D. (2015): Genetically encoded sensor analysis with spatial and temporal Resolution by time-lapse imaging.
    PUB
     
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    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912556
    Binder, D.; Probst, C.; Bier, C.; Loeschcke, A.; Grünberger, A. (2015): Lichtgesteuerte Genexpression auf Einzelzellebene Biospektrum,21:(6): 612-615.
    PUB | DOI
     
  • [109]
    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912563
    Sachs, C. C.; Helfrich, S.; Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D.; Nöh, K. (2015): High-throughput, long-term growth characterization of C. glutamicum on single cell level using the Mother Machine.
    PUB
     
  • [108]
    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912804
    Krämer, C.; Helfrich, S.; Singh, A.; Grünberger, A.; Wiechert, W.; Nöh, K.; Kohlheyer, D. (2015): Instantaneous microfluidic metabolic activity sensing for non-invasive single cell physiology analysis of a prokaryote and its descendants.
    PUB
     
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    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912763
    Grünberger, A. (2015): Microfluidic Single-Cell Cultivation: The key for next generation bioprocess development?
    PUB
     
  • [106]
    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912542
    Probst, C.; Grünberger, A.; Binder, D.; Steffen, I.; Wiechert, W.; Kohlheyer, D. (2015): Optical control of gene expression in bacteria on the single-cell level by caged compounds.
    PUB
     
  • [105]
    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912559
    Sachs, C. C.; Helfrich, S.; Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D.; Nöh, K. (2015): High-throughput long-term growth characterization of C. glutamicum on single cell using the Mother Machine.
    PUB
     
  • [104]
    2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912566
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2015): Single-Cell Bioreactors: Cutting Edge Cultivation Devices for the Ultimate Scale-Down of Bioprocesses.
    PUB
     
  • [103]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912605
    Schendzielorz, G.; Dippong, M.; Grünberger, A.; Kohlheyer, D.; Yoshida, A.; Binder, S.; Nishiyama, C.; Nishiyama, M.; Bott, M.; Eggeling, L. (2014): Taking Control over Control: Use of Product Sensing in Single Cells to Remove Flux Control at Key Enzymes in Biosynthesis Pathways ACS Synthetic Biology,3:(1): 21–29.
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    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912594 OA
    Binder, D.; Grünberger, A.; Loeschcke, A.; Probst, C.; Bier, C.; Pietruszka, J.; Wiechert, W.; Kohlheyer, D.; Jaeger, K. - E.; Drepper, T. (2014): Light-responsive control of bacterial gene Expression: precise triggering of the lac promoter activity using photocaged IPTG Integrative biology,6:(8): 755-765.
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    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912573 OA
    Mustafi, N.; Grünberger, A.; Mahr, R.; Helfrich, S.; Nöh, K.; Blombach, B.; Kohlheyer, D.; Frunzke, J. (2014): Application of a Genetically Encoded Biosensor for Live Cell Imaging of L-Valine Production in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains PLoS one,9:(1):e85731
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912589
    Helfrich, S.; Krämer, C.; Grünberger, A.; Azzouzi, C. E.; Pfeifer, E.; Frunzke, J.; Wiechert, W.; Kohlheyer, D.; Nöh, K. (2014): Microfluids as platform for the spatiotemporal analysis of bacterial populations at single-cell level.
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912591
    Grünberger, A.; Probst, C.; Frunzke, J.; Noack, S.; Wiechert, W.; Kohlheyer, D. (2014): Microfluidic Single-Cell Cultivation: Opportunity for Industrial Bioprocess Development.
    PUB
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912596
    Grünberger, A.; Probst, C.; Unthan, S.; Mustafi, N.; Frunzke, J.; Noack, S.; Wiechert, W.; Kohlheyer, D. (2014): Single-cell cultivation in picoliter scale: Opportunity for bioprocess development.
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    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912616
    Unthan, S.; Grünberger, A.; van Ooyen, J.; Gätgens, J.; Heinrich, J.; Paczia, N.; Wiechert, W.; Kohlheyer, D.; Noack, S. (2014): Beyond growth rate 0.6. What drives Corynebacterium glutamicum to higher growth rates in defined medium Biotechnology and bioengineering,111:(2): 359–371.
    PUB | DOI | WoS | PubMed | Europe PMC
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912806
    Binder, D.; Grünberger, A.; Loeschcke, A.; Probst, C.; Bier, C.; Pietruszka, J.; Wiechert, W.; Kohlheyer, D.; Jäger, K. - E.; Drepper, T. (2014): Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducers.
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    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912730 OA
    Nanda, A. M.; Heyer, A.; Kramer, C.; Grünberger, A.; Kohlheyer, D.; Frunzke, J. (2014): Analysis of SOS-Induced Spontaneous Prophage Induction in Corynebacterium glutamicum at the Single-Cell Level Journal of Bacteriology,196:(1): 180-188.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912766
    Grünberger, A. (2014): Picoliter Bioreactors. Learning from Single Cells about Large Scale Processes.
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912805
    Kohlheyer, D.; Grünberger, A.; Weber, S.; Nedbal, L.; Wiechert, W. (2014): Microfluidic Single-Cell Analysis – Potential for Microalgae Research?
    PUB
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912808
    Mahr, R.; Mustafi, N.; Grünberger, A.; Helfrich, S.; Nöh, K.; Kohlheyer, D.; Frunzke, J. (2014): Metabolite biosensors for single cell analysis and the development of production strains.
    PUB
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912586
    Helfrich, S.; Azzouzi, C. E.; Krämer, C.; Pfeifer, E.; Grünberger, A.; Mustafi, N.; Wiechert, W.; Frunzke, J.; Kohlheyer, D.; Nöh, K. (2014): Microbial Populations on the Microfluidic Analyst's Couch: Approaching Cellular Heterogeneity.
    PUB
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912588
    Helfrich, S.; Grünberger, A.; Kohlheyer, D.; Wiechert, W.; Nöh, K. (2014): Investigating single-cell growth of microbial cell factories: is counting cells enough?
    PUB
     
  • [89]
    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912590
    Mahr, R.; Mustafi, N.; Grünberger, A.; Helfrich, S.; Nöh, K.; Kohlheyer, D.; Frunzke, J. (2014): Transcription factor-based biosensor for microbial strain development.
    PUB
     
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    2014 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912593
    Grünberger, A.; Unthan, S.; Mahr, R.; Frunzke, J.; Noack, S.; Wiechert, W.; Kohlheyer, D. (2014): Systematic screening of single-cell growth and production in a picoliter cultivation platform Chemie Ingenieur Technik,86:(9): 1408.
    PUB | DOI
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912595
    Kohlheyer, D.; Grünberger, A.; Probst, C.; Helfrich, S.; Frunzke, J.; Eggeling, L.; Nöh, K.; Noack, S.; Wiechert, W. (2014): Single-cell Bioreactors boost Bioprocess Development: New Insights into Cellular Metabolism.
    PUB
     
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    2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912601
    Grünberger, A.; Schmitz, K.; Probst, C.; Noack, S.; Wiechert, W.; Kohlheyer, D. (2014): Simple microfluidics for complex organisms: A microfluidic chip System for growth and Morphogenesis studies of filamentous fungi. In: 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013). Red Hook, NY: Curran.
    PUB
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912569
    Binder, D.; Grünberger, A.; Loeschcke, A.; Probst, C.; Bier, C.; Pietruszka, J.; Wiechert, W.; Kohlheyer, D.; Jaeger, K. - E.; Drepper, T. (2014): Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducers.
    PUB
     
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    2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912571
    Grünberger, A.; Probst, C.; Helfrich, S.; Frunzke, J.; Noack, S.; Nöh, K.; Wiechert, W.; Kohlheyer, D. (2014): Microfluidic Single-Cell Analysis Platform for Biotechnological Process Development. In: MicroTAS 2014. San Diego, California: CBM Society. S. 3 p.
    PUB
     
  • [83]
    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912576
    Dusny, C.; Grünberger, A.; Wiechert, W.; Kohlheyer, D.; Schmid, A. (2014): From extracellular Environment to functional phenotype. Quantitative comparison of single cell physiology in static and steady environments.
    PUB
     
  • [82]
    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912583
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2014): Picoliter Bioreactors. Learning from Single Cells about Large-Scale Bioprocesses.
    PUB
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912587
    Mahr, R.; Mustafi, N.; Grünberger, A.; Helfrich, S.; Nöh, K.; Kohlheyer, D.; Frunzke, J. (2014): Metabolite biosensors for single cell analysis and the development of production strains.
    PUB
     
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    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912575
    Krämer, C.; Helfrich, S.; Azzouzi, C. E.; Grünberger, A.; Pfeifer, E.; Frunzke, J.; Wiechert, W.; Nöh, K.; Kohlheyer, D. (2014): Microfluidics as platform for the spatiotemporal analysis of bacterial populations at single-cell level.
    PUB
     
  • [79]
    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912582
    Grünberger, A.; Probst, C.; Nanda, A.; Frunzke, J.; Wiechert, W.; Kohlheyer, D. (2014): Microfluidic Single-Cell Cultivation Systems: Versatile Tools for Microbiology.
    PUB
     
  • [78]
    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912823
    Mahr, R.; Mustafi, N.; Grünberger, A.; Helfrich, S.; Nöh, K.; Kohlheyer, D.; Frunzke, J. (2014): Application of a genetically-encoded metabolite sensor for single cell analysis and development of production strains.
    PUB
     
  • [77]
    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912814
    Grünberger, A.; Probst, C. (2014): Introduction into Microfluidic Single-Cell Analysis.
    PUB
     
  • [76]
    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912585
    Sachs, C. C.; Grünberger, A.; Wiechert, W.; Nöh, K.; Kohlheyer, D. (2014): Robust Automated Image Analysis of Mother Machine Microfluidic Growth Devices.
    PUB
     
  • [75]
    2014 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912592
    Weber, S.; Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2014): Optimizing growth performance of Corynebacterium glutamicum at the single-cell level Chemie Ingenieur Technik,88:(9): 1414.
    PUB | DOI
     
  • [74]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912597
    Grünberger, A.; Wiechert, W.; Kohlheyer, D. (2014): Single-cell microfluidics: opportunity for bioprocess development Current opinion in biotechnology,29: 15-23.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [73]
    2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912580
    Dusny, C.; Grünberger, A.; Rosenthal, K.; Wiechert, W.; Schmid, A. (2014): Quantitative Physiology of Single Cells for Linking Phenotype and Environment.
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  • [72]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912599 OA
    Grünberger, A.; Probst, C.; Heyer, A.; Wiechert, W.; Frunzke, J.; Kohlheyer, D. (2013): Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation Journal of visualized experiments. Bioengineering,82:(82):e50560
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [71]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912606
    Hoffmann, K.; Grünberger, A.; Lausberg, F.; Bott, M.; Eggeling, L. (2013): Visualization of Imbalances in Sulfur Assimilation and Synthesis of Sulfur-Containing Amino Acids at the Single-Cell Level Applied and environmental microbiology,79:(21): 6730-6736.
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912604
    Mahr, R.; Mustafi, N.; Grünberger, A.; Helfrich, S.; Nöh, K.; Kohlheyer, D.; Frunzke, J. (2013): Application of a genetically encoded biosensor for single cell analysis and strain development of production strains.
    PUB
     
  • [69]
    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912609
    Nanda, A.; Heyer, A.; Grünberger, A.; Helfrich, S.; Kohlheyer, D.; Nöh, K.; Frunzke, J. (2013): Single-cell Dynamics of the SOS Response in Corynebacterium glutamicum.
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    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912611 OA
    Probst, C.; Grünberger, A.; Wiechert, W.; Kohlheyer, D. (2013): Polydimethylsiloxane (PDMS) Sub-Micron Traps for Single-Cell Analysis of Bacteria Micromachines,4:(4): 357-369.
    PUB | PDF | DOI | WoS
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912623
    Heyer, A.; Nanda, A.; Grünberger, A.; Kohlheyer, D.; Frunzke, J. (2013): Spontaneous prophage induction in Corynebacterium glutamicum.
    PUB
     
  • [66]
    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912630
    Kohlheyer, D.; Grünberger, A.; Probst, C.; Krämer, C.; Eggeling, L.; Frunzke, J.; Wiechert, W. (2013): Microbial single cell analysis of production strains in microfabricated habitats.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912825
    Binder, D.; Grünberger, A.; Loeschcke, A.; Probst, C.; Pietruszka, J.; Wiechert, W.; Kohlheyer, D.; Jaeger, K. E.; Drepper, T. (2013): Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
    PUB
     
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    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912745
    Grünberger, A.; Lai, P. - K.; Blanco, M. A.; Roberts, C. J. (2013): Coarse-Grained Modeling of Protein Second Osmotic Virial Coefficients: Sterics and Short-Ranged Attractions The Journal of Physical Chemistry B,117:(3): 763-770.
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912810
    Helfrich, S.; Grünberger, A.; Kohlheyer, D.; Wiechert, W.; Nöh, K. (2013): Analysis of microbial observables on single cell level: Challenges of Cell Clusters for Microscopy-based Image Processing.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912824
    Nanda, A. M.; Heyer, A.; Grünberger, A.; Helfrich, S.; Kohlheyer, D.; Nöh, K.; Frunzke, J. (2013): Single-cell dynamics of the SOS response in Corynebacterium glutamicum.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912827
    Mahr, R.; Mustafi, N.; Grünberger, A.; Helfrich, S.; Nöh, K.; Kohlheyer, D.; Frunzke, J. (2013): Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912829
    Sachs, C.; Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2013): Automated image analysis pipeline for single cell bacterial growth studies.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912834
    Binder, D.; Grünberger, A.; Loeschcke, A.; Probst, C.; Pietruszka, J.; Wiechert, W.; Kohlheyer, D.; Jaeger, K. E.; Drepper, T. (2013): Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912836
    Binder, D.; Grünberger, A.; Loeschcke, A.; Probst, C.; Pietruszka, J.; Wiechert, W.; Kohlheyer, D.; Jaeger, K. E.; Drepper, T. (2013): Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912603
    Grünberger, A.; Probst, C.; Unthan, S.; Krämer, C.; Paczia, N.; Noack, S.; Wiechert, W.; Kohlheyer, D. (2013): Single Cell Bioreactors for Bioprocess Optimization.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912608
    Nanda, A.; Heyer, A.; Krämer, C.; Grünberger, A.; Kohlheyer, D.; Frunzke, J. (2013): SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912613
    Probst, C.; Grünberger, A.; Frunzke, J.; Wiechert, W.; Kohlheyer, D. (2013): Microfluidic cultivation technology and application: analysing single-microbes under perfect environmental control.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912615
    Helfrich, S.; Azzouzi, C. E.; Grünberger, A.; Wiechert, W.; Nöh, K. (2013): Explorative Analysis of Cell Population Development: Customizable Interactive Lineage Trees.
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912618
    Kohlheyer, D.; Grünberger, A.; Probst, C.; Frunzke, J.; Wiechert, W. (2013): Picoliter fermentation with single bacteria: Learning from the one to unravel the crowd.
    PUB
     
  • [52]
    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912620
    Noack, S.; Grünberger, A.; van Ooyen, J.; Kohlheyer, D.; Wiechert, W. (2013): Increasing biomass productivity of C. glutamicum - new insights from microscale cultivations.
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912622
    Wiechert, W.; Kohlheyer, D.; Noack, S.; Frunzke, J.; Mustafi, N.; Grünberger, A. (2013): Picoliter Bioreactors. Learning from Single Cells about Large Scale Processes.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912625
    Heinrich, J.; Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2013): Single cell growth under constant environmental conditions and defined C sources: A case study for Corynebacterium glutamicum.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912627
    Probst, C.; Frank, P.; Grünberger, A.; Wiechert, W.; Kohlheyer, D. (2013): Time lapse microbial single cell analysis in a micro fabricated batch reactor.
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    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2614036
    Baumgart, M.; Unthan, S.; Rückert, C.; Sivalingam, J.; Grünberger, A.; Kalinowski, J.; Bott, M.; Noack, S.; Frunzke, J. (2013): Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 - a platform strain for basic research and industrial biotechnology Applied and environmental microbiology,79:(19): 6006-6015.
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912602
    Grünberger, A.; Helfrich, S.; Mustafi, N.; Probst, C.; Frunzke, J.; Nöh, K.; Wiechert, W.; Kohlheyer, D. (2013): Automated High-Throughput Time-Lapse Microscopy of Bacteria Microcolonies in Parallelized Monolayer Growth Chambers.
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912607
    Nanda, A.; Heyer, A.; Krämer, C.; Grünberger, A.; Kohlheyer, D.; Frunzke, J. (2013): SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912614
    Krämer, C.; Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2013): Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912619
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2013): Femtoliter chemostat for long-term bacteria growth and production analysis on single cell level.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912621
    Grünberger, A.; Mustafi, N.; Probst, C.; Frunzke, J.; Wiechert, W.; Kohlheyer, D. (2013): Towards High-Throughput Microbial Single Cell Analysis In Picoliter Bioreactors.
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912626
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2013): Femtoliter chemostat for long-term bacteria growth and production analysis on single cell level.
    PUB
     
  • [41]
    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912809
    Frunzke, J.; Mahr, R.; Grünberger, A.; Mustafi, N.; Kohlheyer, D. (2013): Microbial Metabolite Production – Live in Concert.
    PUB
     
  • [40]
    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912828
    Krämer, C.; Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2013): Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures?
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912830
    Probst, C.; Grünberger, A.; Krämer, C.; Wiechert, W.; Kohlheyer, D. (2013): Microfluidic single-cell analysis in dynamic environments.
    PUB
     
  • [38]
    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912835
    Mahr, R.; Mustafi, N.; Grünberger, A.; Helfrich, S.; Nöh, K.; Kohlheyer, D.; Frunzke, J. (2013): Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains.
    PUB
     
  • [37]
    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912826
    Helfrich, S.; Azzouzi, C. E.; Grünberger, A.; Wiechert, W.; Nöh, K. (2013): Exploration and Analysis of cell population development. Customizable interactive lineage trees.
    PUB
     
  • [36]
    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912833
    Nanda, A. M.; Heyer, A.; Grünberger, A.; Helfrich, S.; Kohlheyer, D.; Nöh, K.; Frunzke, J. (2013): Single-cell dynamics of the SOS response in Corynebacterium glutamicum.
    PUB
     
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    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912600
    Probst, C.; Grünberger, A.; Wiechert, W.; Kohlheyer, D. (2013): Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes Journal of microbiological methods,95:(3): 470-476.
    PUB | DOI | WoS | PubMed | Europe PMC
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912612
    Nanda, A.; Heyer, A.; Krämer, C.; Grünberger, A.; Kohlheyer, D.; Frunzke, J. (2013): SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912617
    Krämer, C.; Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2013): Continuous viability fluorescent staining of growing Corynebacterium glutamicum colonies without sample preparation in an automated microfluidic measurement system.
    PUB
     
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    2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912624
    Grünberger, A.; Mustafi, N.; Probst, C.; Frunzke, J.; Wiechert, W.; Kohlheyer, D. (2013): High-throughput Microbial Single Cell analysis in Picoliter Bioreactors.
    PUB
     
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    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912631
    Grünberger, A.; van Ooyen, J.; Paczia, N.; Rohe, P.; Schendzielorz, G.; Eggeling, L.; Wiechert, W.; Kohlheyer, D.; Noack, S. (2013): Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments Biotechnology and bioengineering,110:(1): 220-228.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [30]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912747
    Scholz, K. E.; Okrob, D.; Kopka, B.; Grünberger, A.; Pohl, M.; Jaeger, K. - E.; Krauss, U. (2012): Synthesis of Chiral Cyanohydrins by Recombinant Escherichia coli Cells in a Micro-Aqueous Reaction System Applied and Environmental Microbiology,78:(14): 5025-5027.
    PUB | DOI | WoS | PubMed | Europe PMC
     
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    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912635
    Binder, S.; Schendzielorz, G.; Kohlheyer, D.; Grünberger, A.; Wiechert, W.; Bott, M.; Eggeling, L. (2012): Metabolite sensors for single-cell isolation of producing bacteria.
    PUB
     
  • [28]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912642
    Grünberger, A.; Frank, P.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2012): Single Cell Microfluidics: From Fabrication to Application.
    PUB
     
  • [27]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912647
    Helfrich, S.; Grünberger, A.; Kohlheyer, D.; Wiechert, W.; Nöh, K. (2012): Semi-Automated Evaluation of Microbial Observables from High-Throughput Time-lapse Microscopy.
    PUB
     
  • [26]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912767
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2012): Fermentation at Picoliter Scale: Microfluidics for single cell analysis of prokaryotic production strains.
    PUB
     
  • [25]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912837
    Probst, C.; Grünberger, A.; Wiechert, W.; Kohlheyer, D. (2012): Screening of Escherichia coli on single-cell level by hyphenating microfluidic picoliter fermentation and optical tweezers.
    PUB
     
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    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912728 OA
    Grünberger, A.; Paczia, N.; Probst, C.; Schendzielorz, G.; Eggeling, L.; Noack, S.; Wiechert, W.; Kohlheyer, D. (2012): A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level Lab on a Chip,12:(11): 2060-2068.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [23]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912776
    Grünberger, A.; Probst., C.; Frank, P.; Wiechert, W.; Kohlheyer, D. (2012): Single Cell Analysis of Industrially Relevant Bacterial Strains in Picoliter Environments.
    PUB
     
  • [22]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912839
    Probst, C.; Grünberger, A.; Wiechert, W.; Kohlheyer, D. (2012): Phenotypic Sorting and Analysis of Bacteria Production Strains using Optical Tweezers and Microfluidics.
    PUB
     
  • [21]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912841
    Nanda, A. M.; Grünberger, A.; Heyer, A.; Helfrich, S.; Kohlheyer, D.; Nöh, K.; Frunzke, J. (2012): Dynamics of the SOS response in single cells of Corynebacterium glutamicum.
    PUB
     
  • [20]
    2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912639
    Probst, C.; Grünberger, A.; Kohlheyer, D.; Wiechert, W. (2012): Phenotypic Sorting and Analysis of Bacteria ProductionStrains Using Optical Tweezers and Microfluidics Chemie - Ingenieur - Technik: CIT,84:(8): 1344.
    PUB | DOI
     
  • [19]
    2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912641
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2012): Femtoliter Growth Channels. Bacteria Long-Term Growth Patterns Analysis on Singel Cell Level Chemie - Ingenieur - Technik (CIT),84:(8): 1407.
    PUB | DOI
     
  • [18]
    2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912646
    Grünberger, A.; Helfrich, S.; Probst, C.; Nöh, K.; Wiechert, W.; Kohlheyer, D. (2012): Industrial Biotechnology meets Microfluidics - Disposable high-throughput single cell analysis device for industrially relevant bacterial strains. In: Stéphane Colin (Hrsg.): Proceedings - µFLU-12. Paris: SHF. (Publications S.H.F., ).
    PUB
     
  • [17]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912633
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2012): Picoliter bioreactors for growth heterogeneity studies of industrially relevant bacteria on single cell level.
    PUB
     
  • [16]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912638
    Mustafi, N.; Grünberger, A.; Helfrich, S.; Kohlheyer, D.; Nöh, K.; Bott, M.; Frunzke, J. (2012): A biosensor for the intracellular detection of L-methionine and branched-chain amino acids - Monitoring of amino acid production at the single cell level.
    PUB
     
  • [15]
    2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912640
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2012): High-Throughput Growth Rate Determination of Bacteria Micro colonies on Single Cell Level Chemie - Ingenieur - Technik: CIT,84:(8): 1336-1337.
    PUB | DOI
     
  • [14]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912645
    Kohlheyer, D.; Grünberger, A.; Probst, C.; Frank, P.; Wiechert, W. (2012): Catch it and batch it: picoliter fermentation at the single cell level.
    PUB
     
  • [13]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912746
    Mustafi, N.; Grünberger, A.; Kohlheyer, D.; Bott, M.; Frunzke, J. (2012): The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acids Metabolic Engineering,14:(4): 449-457.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [12]
    2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912758
    Grünberger, A.; Probst, C.; Binder, S.; Ziaee, R.; Eggeling, L.; Wiechert, W.; Kohlheyer, D. (2012): Single Cell Trapping and Analysis for Prokaryotic Production Strains in Sub-µm Fluidic Structures. In: James Landers (Hrsg.): 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011 (MiroTAS 2011). Red Hook, NY: Curran.
    PUB
     
  • [11]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912777
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2012): Towards high-throughput single cell growth optimization and production analysis using picoliter bioreactors.
    PUB
     
  • [10]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912838
    Frank, P.; Probst, C.; Grünberger, A.; Wiechert, W.; Kohlheyer, D. (2012): “Catch it and Batch it”- Microfluidics single cell batch cultivation utilizing picoliter bioreactors.
    PUB
     
  • [9]
    2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912840
    Nanda, A. M.; Grünberger, A.; Heyer, A.; Helfrich, S.; Kohlheyer, D.; Nöh, K.; Frunzke, J. (2012): Dynamics of the SOS response in single cells of Corynebacterium glutamicum.
    PUB
     
  • [8]
    2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912643
    Grünberger, A.; Helfrich, S.; Probst, C.; Wiechert, W.; Nöh, K.; Kohlheyer, D. (2012): High-Throughput lineage tree investigations of bacteria microcolonies using arrays of monolayer growth chambers. In: Proceedings of The Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2012). San Diego, California: CBMS.
    PUB
     
  • [7]
    2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912778
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2011): Single Cell Trapping and Analysis for Prokaryotic Production Strains in Sub -µm Fluidic Structures.
    PUB
     
  • [6]
    2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912843
    Scholz, K. E.; Okrob, D.; Kopka, B.; Grünberger, A.; Pohl, M.; Jaeger, K. E.; Krauss, U. (2011): Fluorescence reporters for the analysis of whole cell biocatalysts in non-conventional media.
    PUB
     
  • [5]
    2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912811
    Kohlheyer, D.; Grünberger, A.; Probst, C.; Wiechert, W. (2011): Sub-µm Fluidic Structures for Single Cell Trapping and Analysis of Prokaryotic Production Strains.
    PUB
     
  • [4]
    2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912842
    Mustafi, N.; Grünberger, A.; Kohlheyer, D.; Bott, M.; Frunzke, J. (2011): A biosensor for the intracellular detection of L-methionine and branched-chain amino acids.
    PUB
     
  • [3]
    2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912768
    Grünberger, A.; Probst, C.; Wiechert, W.; Kohlheyer, D. (2011): A continuous picoliter bioreactor for heterogeneity studies of bacteria microcolonies.
    PUB
     
  • [2]
    2010 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912812
    Blanko, M. A.; Grünberger, A.; Sahin, E.; Roberts, C. J. (2010): Protein Interactions from Kirwood-Buff Analysis of Light Scattering and Coarse-Grained Molecular Models.
    PUB
     
  • [1]
    2009 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912813
    Grünberger, A.; Stephens, E.; Hankamer, B. (2009): Media optimization for the microalgae Chamydomonas reinhardtii Stm6 using statistical design.
    PUB
     
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