30 Publikationen
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2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2987506Sawant, Kaustubh R., Sarnaik, Aditya P., Singh, Rabinder, Savvashe, Prashant, Baier, Thomas, Kruse, Olaf, Jutur, Pannaga Pavan, Lali, Arvind, and Pandit, Reena A. “Outdoor cultivation and metabolomics exploration of Chlamydomonas engineered for bisabolene production”. Bioresource Technology (2024): 130513.PUB | DOI | PubMed | Europe PMC
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2985148Einhaus, Alexander, Baier, Thomas, and Kruse, Olaf. “Molecular design of microalgae as sustainable cell factories”. Trends in Biotechnology (2023).PUB | PDF | DOI | Download (ext.) | PubMed | Europe PMC
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2969153Amendola, Sofia, Kneip, Jacob S., Meyer, Florian, Perozeni, Federico, Cazzaniga, Stefano, Lauersen, Kyle J., Ballottari, Matteo, and Baier, Thomas. “Metabolic Engineering for Efficient Ketocarotenoid Accumulation in the Green Microalga Chlamydomonas reinhardtii”. ACS Synthetic Biology (2023).PUB | DOI | WoS | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2960644Freudenberg, Robert, Wittemeier, Luisa, Einhaus, Alexander, Baier, Thomas, and Kruse, Olaf. “The Spermidine Synthase Gene SPD1: A Novel Auxotrophic Marker for Chlamydomonas Reinhardtii Designed by Enhanced CRISPR/Cas9 Gene Editing”. Cells 11.5 (2022): 837.PUB | PDF | DOI | Preprint
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2964020Freudenberg, Robert, Wittemeier, Luisa, Einhaus, Alexander, Baier, Thomas, and Kruse, Olaf. “Advanced pathway engineering for phototrophic putrescine production”. Plant Biotechnology Journal (2022).PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2964469Cazzaniga, Stefano, Perozeni, Federico, Baier, Thomas, and Ballottari, Matteo. “Engineering astaxanthin accumulation reduces photoinhibition and increases biomass productivity under high light in Chlamydomonas reinhardtii”. Biotechnology for Biofuels and Bioproducts 15.1 (2022): 77.PUB | DOI | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2963965Einhaus, Alexander, Steube, Jasmin, Freudenberg, Robert, Barczyk, Jonas, Baier, Thomas, and Kruse, Olaf. “Engineering a powerful green cell factory for robust photoautotrophic diterpenoid production”. Metabolic Engineering 73 (2022): 82-90.PUB | DOI | WoS | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949462Freudenberg, Robert, Baier, Thomas, Einhaus, Alexander, Wobbe, Lutz, and Kruse, Olaf. “High cell density cultivation enables efficient and sustainable recombinant polyamine production in the microalga Chlamydomonas reinhardtii”. Bioresource Technology 323 (2021): 124542.PUB | DOI | WoS | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2956071Schilbert, Hanna, Schöne, Maximilian, Baier, Thomas, Busche, Mareike, Viehöver, Prisca, Weisshaar, Bernd, and Holtgräwe, Daniela. “Characterization of the Brassica napus flavonol synthase gene family reveals bifunctional flavonol synthases”. Frontiers in Plant Science 12 (2021): 733762.PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC | Preprint | EBI - ENA Project
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953317Einhaus, Alexander, Baier, Thomas, Rosenstengel, Marian, Freudenberg, Robert, and Kruse, Olaf. “Rational Promoter Engineering Enables Robust Terpene Production in Microalgae”. ACS Synthetic Biology 10.4 (2021): 847–856.PUB | DOI | WoS | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2955404Dementyeva, Polina, Freudenberg, Robert A., Baier, Thomas, Rojek, Kristin, Wobbe, Lutz, Weisshaar, Bernd, and Kruse, Olaf. “A novel, robust and mating-competent Chlamydomonas reinhardtii strain with an enhanced transgene expression capacity for algal biotechnology”. Biotechnology Reports (2021): e00644.PUB | DOI | Download (ext.) | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2951395Blifernez-Klassen, Olga, Berger, Hanna, Mittmann, Birgit Gerlinde Katharina, Klassen, Viktor, Schelletter, Louise, Buchholz, Tatjana, Baier, Thomas, Soleimani, Maryna, Wobbe, Lutz, and Kruse, Olaf. “A gene regulatory network for antenna size control in carbon dioxide-deprived cells”. The Plant Cell (2021): koab012.PUB | DOI | WoS | PubMed | Europe PMC
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2945180Baier, Thomas, Jacobebbinghaus, Nick, Einhaus, Alexander, Lauersen, Kyle J., and Kruse, Olaf. “Introns mediate post-transcriptional enhancement of nuclear gene expression in the green microalga Chlamydomonas reinhardtii”. PLOS Genetics 16.7 (2020): e1008944.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2941708Perozeni, Federico, Cazzaniga, Stefano, Baier, Thomas, Zanoni, Francesca, Zoccatelli, Gianni, Lauersen, Kyle J., Wobbe, Lutz, and Ballottari, Matteo. “Turning a green alga red: engineering astaxanthin biosynthesis by intragenic pseudogene revival in Chlamydomonas reinhardtii”. Plant biotechnology journal 18.10 (2020): 2053-2067.PUB | DOI | WoS | PubMed | Europe PMC | Preprint
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2020 | Preprint | Veröffentlicht | PUB-ID: 2946454Blifernez-Klassen, Olga, Berger, Hanna, Mittmann, Birgit, Klassen, Viktor, Schelletter, Louise, Buchholz, Tatjana, Baier, Thomas, Soleimani, Maryna, Wobbe, Lutz, and Kruse, Olaf. “A transcriptional regulatory circuit for the photosynthetic acclimation of microalgae to carbon dioxide limitation”. bioRxiv (2020).PUB | DOI | Preprint
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2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2933685Löwe, Jana, Blifernez-Klassen, Olga, Baier, Thomas, Wobbe, Lutz, Kruse, Olaf, and Gröger, Harald. “Type II flavoprotein monooxygenase PsFMO_A from the bacterium Pimelobacter sp. Bb-B catalyzes enantioselective Baeyer-Villiger oxidations with a relaxed cofactor specificity.”. Journal of biotechnology 294 (2019): 81-87.PUB | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2931825Baier, Thomas, Kros, Dana, Feiner, Rebecca, Lauersen, Kyle J., Müller, Kristian, and Kruse, Olaf. “Engineered Fusion Proteins for Efficient Protein Secretion and Purification of a Human Growth Factor from the Green Microalga Chlamydomonas reinhardtii”. ACS Synthetic Biology 7.11 (2018): 2547-2557.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2921210Lauersen, Kyle J., Wichmann, Julian, Baier, Thomas, Kampranis, Sotirios C., Pateraki, Irini, Lindberg Møller, Birger, and Kruse, Olaf. “Phototrophic production of heterologous diterpenoids and a hydroxy-functionalized derivative from Chlamydomonas reinhardtii”. Metabolic Engineering 49 (2018): 116-127.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2919149Henke, Nadja Alina, Wichmann, Julian, Baier, Thomas, Frohwitter, Jonas, Lauersen, Kyle J., Risse, Joe Max, Peters-Wendisch, Petra, Kruse, Olaf, and Wendisch, Volker F. “Patchoulol production with metabolically engineered Corynebacterium glutamicum”. Genes 9.4 (2018): 219.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2930755Crozet, Pierre, Navarro, Francisco J, Willmund, Felix, Mehrshahi, Payam, Bakowski, Kamil, Lauersen, Kyle J., Pérez-Pérez, Maria-Esther, Auroy, Pascaline, Gorchs Rovira, Aleix, Sauret-Gueto, Susana, Niemeyer, Justus, Spaniol, Benjamin, Theis, Jasmine, Trösch, Raphael, Westrich, Lisa-Desiree, Vavitsas, Konstantinos, Baier, Thomas, Hübner, Wolfgang, de Carpentier, Felix, Cassarini, Mathieu, Danon, Antoine, Henri, Julien, Marchand, Christophe H, de Mia, Marcello, Sarkissian, Kevin, Baulcombe, David C., Peltier, Gilles, Crespo, Jose L., Kruse, Olaf, Jensen, Poul Erik, Schroda, Michael, Smith, Alison G., and Lemaire, Stéphane D. “Birth of a photosynthetic chassis. A MoClo toolkit enabling synthetic biology in the microalga Chlamydomonas reinhardtii”. ACS Synthetic Biology 7.9 (2018): 2074-2086.PUB | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2915928Wichmann, Julian, Baier, Thomas, Wentnagel, Eduard, Lauersen, Kyle J., and Kruse, Olaf. “Tailored carbon partitioning for phototrophic production of (E)-α-bisabolene from the green microalga Chlamydomonas reinhardtii”. Metabolic Engineering 45 (2018): 211-222.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920779Baier, Thomas, Wichmann, Julian, Kruse, Olaf, and Lauersen, Kyle J. “Intron-containing algal transgenes mediate efficient recombinant gene expression in the green microalga Chlamydomonas reinhardtii”. Nucleic Acids Research 46.13 (2018): 6909-6919.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2018 | Dissertation | Veröffentlicht | PUB-ID: 2931309Baier, Thomas. Strategien zur Optimierung der heterologen Proteinproduktion in der eukaryotischen Mikroalge Chlamydomonas reinhardtii. Bielefeld: Universität Bielefeld, 2018.PUB
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2913216Venkanna, Deepak, Südfeld, Christian, Baier, Thomas, Homburg, Sarah Vanessa, Patel, Anant, Wobbe, Lutz, and Kruse, Olaf. “Knock-Down of the IFR1 Protein Perturbs the Homeostasis of Reactive Electrophile Species and Boosts Photosynthetic Hydrogen Production in <i>Chlamydomonas reinhardtii</i>”. Frontiers in Plant Science 8 (2017): 1347.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904856Lauersen, Kyle J., Baier, Thomas, Wichmann, Julian, Wördenweber, Robin, Mussgnug, Jan H., Hübner, Wolfgang, Huser, Thomas, and Kruse, Olaf. “Efficient phototrophic production of a high-value sesquiterpenoid from the eukaryotic microalga Chlamydomonas reinhardtii”. Metabolic Engineering 38 (2016): 331-343.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2753011Lauersen, Kyle J., Huber, Isabel, Wichmann, Julian, Baier, Thomas, Leiter, Andreas, Gaukel, Volker, Kartushin, Viktor, Rattenholl, Anke, Steinweg, Christian, von Riesen, Lena, Posten, Clemens, Gudermann, Frank, Lütkemeyer, Dirk, Mussgnug, Jan H., and Kruse, Olaf. “Investigating the dynamics of recombinant protein secretion from a microalgal host”. Journal of Biotechnology 215 (2015): 62-71.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2946455Tcheremenskaia, Olga, Benigni, Romualdo, Nikolova, Ivelina, Jeliazkova, Nina, Escher, Sylvia E, Batke, Monika, Baier, Thomas, Poroikov, Vladimir, Lagunin, Alexey, Rautenberg, Micha, and Hardy, Barry. “OpenTox predictive toxicology framework: toxicological ontology and semantic media wiki-based OpenToxipedia”. Journal of Biomedical Semantics 3.Suppl 1 (2012): S7.PUB | DOI