41 Publikationen
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2023 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2988204Diem, E., Lu, C., Beckstette, M., Floess, S., Lochner, M.: Epigenetic profiling of murine innate lymphoid cells under homeostatic and acute/memory-like inflammatory conditions. Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France. European Journal of Immunology. 53, p. 238. Wiley, Hoboken (2023).PUB | WoS
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2023 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2988223Yu, Z., Nair, V., Bonifacius, A., Khan, F., Beckstette, M., Niemz, J., Hilgendorf, P., Pietzsch, B., Keller, A., Falk, C., Busch, D., Brinkmann, M., Schober, K., Sain, L., Muller, F., Vesper, B., Floess, S., Huehn, J.: TBKBP1 is a novel player modulating the cytotoxic function of human cytomegalovirus-specific CD8+T cells. European Journal of Immunology. 53, 113 (2023).PUB | WoS
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2023 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2988234Sasidharan, Nair, V., Yu, Z., Bonifacius, A., Beckstette, M., Niemz, J., Pietzsch, B., Busch, D., Cicin-Sain, L., Muller, F., Eiz-Vesper, B., Floess, S., Huehn, J.: Role of ZEB2 in the function of antigen-specific human CD8+T cells. European Journal of Immunology . 53, 143 (2023).PUB | WoS
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2983209Hassa, J., Tubbesing, T.J., Maus, I., Heyer, R., Benndorf, D., Effenberger, M., Henke, C., Osterholz, B., Beckstette, M., Pühler, A., Sczyrba, A., Schlüter, A.: Uncovering Microbiome Adaptations in a Full-Scale Biogas Plant: Insights from MAG-Centric Metagenomics and Metaproteomics. Microorganisms. 11, : 2412 (2023).PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
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2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2978079Boldt, J., Lukoseviciute, L., Fu, C., Steglich, M., Bunk, B., Junker, V., Gollasch, A., Trunkwalter, B., Mohr, K.I., Beckstette, M., Wink, J., Overmann, J., Müller, R., Nübel, U.: Bursts in biosynthetic gene cluster transcription are accompanied by surges of natural compound production in the myxobacterium Sorangium sp. Microbial Biotechnology . (2023).PUB | PDF | DOI | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2967522Pezoldt, J., Wiechers, C., Zou, M., Litovchenko, M., Biocanin, M., Beckstette, M., Sitnik, K., Palatella, M., van Mierlo, G., Chen, W., Gardeux, V., Floess, S., Ebel, M., Russeil, J., Arampatzi, P., Vafardanejad, E., Saliba, A.-E., Deplancke, B., Huehn, J.: Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34(+) stromal cell subsets. Nature Communications. 13, : 7227 (2022).PUB | DOI | WoS | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2965101Beckstette, M., Lu, C.-W., Herppich, S., Diem, E.C., Ntalli, A., Ochel, A., Kruse, F., Pietzsch, B., Neumann, K., Huehn, J., Floess, S., Lochner, M.: Profiling of epigenetic marker regions in murine ILCs under homeostatic and inflammatory conditions. Journal of Experimental Medicine. 219, : e20210663 (2022).PUB | DOI | WoS | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2957501Brandt, D., Simunovic, M., Busche, T., Haak, M., Belmann, P., Jünemann, S., Schulz, T., Klages, L.J., Vinke, S., Beckstette, M., Pohl, E., Scherer, C., Sczyrba, A., Kalinowski, J.: Multiple Occurrences of a 168-Nucleotide Deletion in SARS-CoV-2 ORF8, Unnoticed by Standard Amplicon Sequencing and Variant Calling Pipelines. Viruses. 13, : 1870 (2021).PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2941645Maus, I., Klocke, M., Derenkó, J., Stolze, Y., Beckstette, M., Jost, C., Wibberg, D., Blom, J., Henke, C., Willenbücher, K., Rumming, M., Rademacher, A., Pühler, A., Sczyrba, A., Schlüter, A.: Impact of process temperature and organic loading rate on cellulolytic / hydrolytic biofilm microbiomes during biomethanation of ryegrass silage revealed by genome-centered metagenomics and metatranscriptomics. Environmental Microbiome. 15, : 7 (2020).PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953267Schulte-Schrepping, J., Reusch, N., Paclik, D., Baßler, K., Schlickeiser, S., Zhang, B., Krämer, B., Krammer, T., Brumhard, S., Bonaguro, L., De Domenico, E., Wendisch, D., Grasshoff, M., Kapellos, T.S., Beckstette, M., Pecht, T., Saglam, A., Dietrich, O., Mei, H.E., Schulz, A.R., Conrad, C., Kunkel, D., Vafadarnejad, E., Xu, C.-J., Horne, A., Herbert, M., Drews, A., Thibeault, C., Pfeiffer, M., Hippenstiel, S., Hocke, A., Müller-Redetzky, H., Heim, K.-M., Machleidt, F., Uhrig, A., Bosquillon de Jarcy, L., Jürgens, L., Stegemann, M., Glösenkamp, C.R., Volk, H.-D., Goffinet, C., Landthaler, M., Wyler, E., Georg, P., Schneider, M., Dang-Heine, C., Neuwinger, N., Kappert, K., Tauber, R., Corman, V., Raabe, J., Kaiser, K.M., Vinh, M.T., Rieke, G., Meisel, C., Ulas, T., Becker, M., Geffers, R., Witzenrath, M., Drosten, C., Suttorp, N., von Kalle, C., Kurth, F., Händler, K., Schultze, J.L., Aschenbrenner, A.C., Li, Y., Nattermann, J., Sawitzki, B., Saliba, A.-E., Sander, L.E., Angelov, A., Bals, R., Bartholomäus, A., Becker, A., Bezdan, D., Bonifacio, E., Bork, P., Clavel, T., Colome-Tatche, M., Diefenbach, A., Dilthey, A., Fischer, N., Förstner, K., Frick, J.-S., Gagneur, J., Goesmann, A., Hain, T., Hummel, M., Janssen, S., Kalinowski, J., Kallies, R., Kehr, B., Keller, A., Kim-Hellmuth, S., Klein, C., Kohlbacher, O., Korbel, J.O., Kurth, I., Landthaler, M., Li, Y., Ludwig, K., Makarewicz, O., Marz, M., McHardy, A., Mertes, C., Nöthen, M., Nürnberg, P., Ohler, U., Ossowski, S., Overmann, J., Peter, S., Pfeffer, K., Poetsch, A.R., Pühler, A., Rajewsky, N., Ralser, M., Rieß, O., Ripke, S., Nunes da Rocha, U., Rosenstiel, P., Saliba, A.-E., Sander, L.E., Sawitzki, B., Schiffer, P., Schulte, E.-C., Schultze, J.L., Sczyrba, A., Stegle, O., Stoye, J., Theis, F., Vehreschild, J., Vogel, J., von Kleist, M., Walker, A., Walter, J., Wieczorek, D., Ziebuhr, J.: Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment. Cell. 182, 1419-1440.e23 (2020).PUB | DOI | WoS | PubMed | Europe PMC
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953280Schäfer, H., Beckert, B., Frese, C.K., Steinchen, W., Nuss, A.M., Beckstette, M., Hantke, I., Driller, K., Sudzinová, P., Krásný, L., Kaever, V., Dersch, P., Bange, G., Wilson, D.N., Turgay, K.: The alarmones (p)ppGpp are part of the heat shock response of Bacillus subtilis. PLOS Genetics. 16, : e1008275 (2020).PUB | DOI | WoS | PubMed | Europe PMC | Preprint
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2020 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2953279Ciurkiewicz, M., Floess, S., Beckstette, M., Kummerfeld, M., Baumgärtner, W., Huehn, J., Beineke, A.: Transkriptomanalysen in der Frühphase der Theilervirusinfektion zeigen Unterschiede in der angeborenen Immunantwort und Antigenpräsentation bei SJL- und C57BL/6-Mäusen. 63. Jahrestagung der Fachgruppe Pathologie der Deutschen Veterinärmedizinischen Gesellschaft. Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere. 48, p. 220. Georg Thieme Verlag, Stuttgart (2020).PUB | DOI
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953282Pezoldt, J., Erhard, F., Beckstette, M., Wiechers, C., Herppich, S., Bulat, T., Brendolan, A., Huehn, J., Kalinke, U., Müller, M., Strobl, B., Deplancke, B., Cicin-Sain, L., Sitnik, K.M.: Innate Antiviral Specialization of Ly6C+CD45+ Splenic Red Pulp Stroma Instilled by Subset-Specific Regulation of Cellular Sensitivity to Type I Interferons. SSRN Electronic Journal. (2020).PUB | DOI
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953283Ciurkiewicz, M., Floess, S., Beckstette, M., Kummerfeld, M., Baumgartner, W., Huehn, J., Beineke, A.: Early Transcriptional Differences in the Brain of Theiler’s Virus-infected Mouse Strains Reveal Delayed Antiviral Immune Responses in SJL/J mice. Journal of Comparative Pathology. 174, : 178 (2020).PUB | DOI
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953286Schmühl, C., Beckstette, M., Heroven, A.K., Bunk, B., Spröer, C., McNally, A., Overmann, J., Dersch, P.: Comparative Transcriptomic Profiling of O:3 and O:8 Reveals Major Expression Differences of Fitness- and Virulence-Relevant Genes Indicating Ecological Separation. mSystems. 4, (2019).PUB | DOI | WoS | PubMed | Europe PMC
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953287Berndt, V., Beckstette, M., Volk, M., Dersch, P., Brönstrup, M.: Metabolome and transcriptome-wide effects of the carbon storage regulator A in enteropathogenic Escherichia coli. Scientific Reports. 9, : 138 (2019).PUB | DOI | WoS | PubMed | Europe PMC
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2019 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2953285Kusmierek, M., Heroven, A.K., Beckstette, M., Nuss, A.M., Dersch, P.: Discovering Yersinia–Host Interactions by Tissue Dual RNA-Seq. In: Vadyvaloo, V. and Lawrenz, M.B. (eds.) Pathogenic Yersinia. Methods and Protocols. Methods in Molecular Biology. 2010, p. 99-116. Springer , New York, NY (2019).PUB | DOI
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953288Berges, M., Michel, A.-M., Lassek, C., Nuss, A.M., Beckstette, M., Dersch, P., Riedel, K., Sievers, S., Becher, D., Otto, A., Maaß, S., Rohde, M., Eckweiler, D., Borrero-de Acuña, J.M., Jahn, M., Neumann-Schaal, M., Jahn, D.: Iron Regulation in Clostridioides difficile. Frontiers in Microbiology. 9, : 3183 (2018).PUB | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953289Pezoldt, J., Pasztoi, M., Zou, M., Wiechers, C., Beckstette, M., Thierry, G.R., Vafadarnejad, E., Floess, S., Arampatzi, P., Buettner, M., Schweer, J., Fleissner, D., Vital, M., Pieper, D.H., Basic, M., Dersch, P., Strowig, T., Hornef, M., Bleich, A., Bode, U., Pabst, O., Bajénoff, M., Saliba, A.-E., Huehn, J.: Neonatally imprinted stromal cell subsets induce tolerogenic dendritic cells in mesenteric lymph nodes. Nature Communications. 9, : 3903 (2018).PUB | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953291Neumann-Schaal, M., Metzendorf, N.G., Troitzsch, D., Nuss, A.M., Hofmann, J.D., Beckstette, M., Dersch, P., Otto, A., Sievers, S.: Tracking gene expression and oxidative damage of O2-stressed Clostridioides difficile by a multi-omics approach. Anaerobe. 53, 94-107 (2018).PUB | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953292Uhde, A.-K., Ciurkiewicz, M., Herder, V., Khan, M.A., Hensel, N., Claus, P., Beckstette, M., Teich, R., Floess, S., Baumgärtner, W., Jung, K., Huehn, J., Beineke, A.: Intact interleukin-10 receptor signaling protects from hippocampal damage elicited by experimental neurotropic virus infection of SJL mice. Scientific Reports. 8, : 6106 (2018).PUB | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953293Heine, W., Beckstette, M., Heroven, A.K., Thiemann, S., Heise, U., Nuss, A.M., Pisano, F., Strowig, T., Dersch, P.: Loss of CNFY toxin-induced inflammation drives Yersinia pseudotuberculosis into persistency. PLOS Pathogens. 14, : e1006858 (2018).PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2914367Sczyrba, A., Hofmann, P., Belmann, P., Koslicki, D., Janssen, S., Dröge, J., Gregor, I., Majda, S., Fiedler, J., Dahms, E., Bremges, A., Fritz, A., Garrido-Oter, R., Jørgensen, T.S., Shapiro, N., Blood, P.D., Gurevich, A., Bai, Y., Turaev, D., DeMaere, M.Z., Chikhi, R., Nagarajan, N., Quince, C., Meyer, F., Balvočiūtė, M., Hansen, L.H., Sørensen, S.J., Chia, B.K.H., Denis, B., Froula, J.L., Wang, Z., Egan, R., Don Kang, D., Cook, J.J., Deltel, C., Beckstette, M., Lemaitre, C., Peterlongo, P., Rizk, G., Lavenier, D., Wu, Y.-W., Singer, S.W., Jain, C., Strous, M., Klingenberg, H., Meinicke, P., Barton, M.D., Lingner, T., Lin, H.-H., Liao, Y.-C., Silva, G.G.Z., Cuevas, D.A., Edwards, R.A., Saha, S., Piro, V.C., Renard, B.Y., Pop, M., Klenk, H.-P., Göker, M., Kyrpides, N.C., Woyke, T., Vorholt, J.A., Schulze-Lefert, P., Rubin, E.M., Darling, A.E., Rattei, T., McHardy, A.C.: Critical Assessment of Metagenome Interpretation—a benchmark of metagenomics software. Nature Methods. 14, 1063-1071 (2017).PUB | DOI | Download (ext.) | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953296Pasztoi, M., Pezoldt, J., Beckstette, M., Lipps, C., Wirth, D., Rohde, M., Paloczi, K., Buzas, E.I., Huehn, J.: Mesenteric lymph node stromal cell-derived extracellular vesicles contribute to peripheral de novo induction of Foxp3 regulatory T cells. European Journal of Immunology. 47, 2142-2152 (2017).PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953297Nikolouli, E., Hardtke-Wolenski, M., Hapke, M., Beckstette, M., Geffers, R., Floess, S., Jaeckel, E., Huehn, J.: Alloantigen-Induced Regulatory T Cells Generated in Presence of Vitamin C Display Enhanced Stability of Foxp3 Expression and Promote Skin Allograft Acceptance. Frontiers in Immunology. 8, : 748 (2017).PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953298Garg, G., Nikolouli, E., Hardtke-Wolenski, M., Toker, A., Ohkura, N., Beckstette, M., Miyao, T., Geffers, R., Floess, S., Gerdes, N., Lutgens, E., Osterloh, A., Hori, S., Sakaguchi, S., Jaeckel, E., Huehn, J.: Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells. Oncotarget. 8, 35542-35557 (2017).PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953299Nuss, A.M., Beckstette, M., Pimenova, M., Schmühl, C., Opitz, W., Pisano, F., Heroven, A.K., Dersch, P.: Tissue dual RNA-seq allows fast discovery of infection-specific functions and riboregulators shaping host–pathogen transcriptomes. Proceedings of the National Academy of Sciences. 114, E791-E800 (2017).PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953300Avican, U., Beckstette, M., Heroven, A.K., Lavander, M., Dersch, P., Forsberg, Å.: Transcriptomic and Phenotypic Analysis Reveals New Functions for the Tat Pathway in Yersinia pseudotuberculosis. Journal of Bacteriology. 198, 2876-2886 (2016).PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953301Yang, B.-H., Hagemann, S., Mamareli, P., Lauer, U., Hoffmann, U., Beckstette, M., Föhse, L., Prinz, I., Pezoldt, J., Suerbaum, S., Sparwasser, T., Hamann, A., Floess, S., Huehn, J., Lochner, M.: Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation. Mucosal Immunology. 9, 444-457 (2016).PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2917100Nuss, A.M., Heroven, A.K., Waldmann, B., Reinkensmeier, J., Jarek, M., Beckstette, M., Dersch, P.: Transcriptomic Profiling of Yersinia pseudotuberculosis Reveals Reprogramming of the Crp Regulon by Temperature and Uncovers Crp as a Master Regulator of Small RNAs. PLOS GENETICS. 11, : e1005087 (2015).PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953303Avican, K., Fahlgren, A., Huss, M., Heroven, A.K., Beckstette, M., Dersch, P., Fällman, M.: Reprogramming of Yersinia from Virulent to Persistent Mode Revealed by Complex In Vivo RNA-seq Analysis. PLOS Pathogens. 11, : e1004600 (2015).PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953304Abdollahpour, H., Alawi, M., Kortüm, F., Beckstette, M., Seemanova, E., Komárek, V., Rosenberger, G., Kutsche, K.: An AP4B1 frameshift mutation in siblings with intellectual disability and spastic tetraplegia further delineates the AP-4 deficiency syndrome. European Journal of Human Genetics. 23, 256-259 (2015).PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953305Meyer, F., Kurtz, S., Beckstette, M.: Fast online and index-based algorithms for approximate search of RNA sequence-structure patterns. BMC Bioinformatics. 14, : 226 (2013).PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953309Meyer, F., Kurtz, S., Backofen, R., Will, S., Beckstette, M.: Structator: fast index-based search for RNA sequence-structure patterns. BMC Bioinformatics. 12, : 214 (2011).PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1589458Beckstette, M., Homann, R., Giegerich, R., Kurtz, S.: Significant speedup of database searches with HMMs by search space reduction with PSSM family models. Bioinformatics. 25, 3251-3258 (2009).PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953311Heyne, S., Will, S., Beckstette, M., Backofen, R.: Lightweight comparison of RNAs based on exact sequence–structure matches. Bioinformatics. 25, 2095-2102 (2009).PUB | DOI | WoS | PubMed | Europe PMC
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2383529Beckstette, M., Mailänder, J.T., Marhöfer, R.J., Sczyrba, A., Ohlebusch, E., Giegerich, R., Selzer, P.M.: Genlight: Interactive high-throughput sequence analysis and comparative genomics. Journal of Integrative Bioinformatics. 1, 90-107 (2004).PUB | DOI
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2004 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2383536Beckstette, M., Sczyrba, A., Selzer, P.M.: Genlight: Interactive high-throughput sequence analysis and comparative genomics. In: Giegerich, R. (ed.) German Conference on Bioinformatics. GCB 2004 ; October 4 - 6, 2004, Bielefeld, Germany . GI-Edition / Proceedings. 53, p. 179-186. Gesellschaft für Informatik, Bonn (2004).PUB
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953316Marian, C.O., Bordoli, S.J., Goltz, M., Santarella, R.A., Jackson, L.P., Danilevskaya, O., Beckstette, M., Meeley, R., Bass, H.W.: The Maize Single myb histone 1 Gene, Smh1, Belongs to a Novel Gene Family and Encodes a Protein That Binds Telomere DNA Repeats in Vitro. Plant Physiology. 133, 1336-1350 (2003).PUB | DOI | WoS | PubMed | Europe PMC