14 Publikationen
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904124Kruszewski, K.; Luellmann-Rauch, R.; Dierks, T.; Bartsch, U.; Damme, M. (2016): Degeneration of Photoreceptor Cells in Arylsulfatase G-Deficient Mice INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,57:(3): 1120-1131.PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2905616Wolf, H.; Damme, M.; Stroobants, S.; D'Hooge, R.; Beck, H. C.; Hermans-Borgmeyer, I.; Lüllmann-Rauch, R.; Dierks, T.; Lübke, T. (2016): A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease Disease Models & Mechanisms,9:(9): 1015-1028.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2709463Kowalewski, B.; Heimann, P.; Ortkras, T.; Lüllmann-Rauch, R.; Sawada, T.; Walkley, S. U.; Dierks, T.; Damme, M. (2015): Ataxia is the major neuropathological finding in Arylsulfatase G deficient mice: Similarities and dissimilarities to Sanfilippo disease (Mucopolysaccharidosis type III) Human Molecular Genetics,24:(7): 1856-1868.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2658538Kong, X. Y.; Nesset, C. K.; Damme, M.; Loeberg, E. - M.; Lübke, T.; Maehlen, J.; Andersson, K. B.; Roos, N.; Thoresen, G. H.; Rustan, A. C.; Kase, E. T.; Eskild, W. (2014): Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells Disease Models & Mechanisms,7:(3): 351-362.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2484642Thelen, M.; Damme, M.; Schweizer, M.; Hagel, C.; Wong, A.; Cooper, J. D.; Braulke, T.; Galliciotti, G. (2012): Disruption of the Autophagy-Lysosome Pathway is Involved in Neuropathology of the nclf Mouse Model of Neuronal Ceroid Lipofuscinosis PLOS ONE,7:(4):e35493PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471754Makrypidi, G.; Damme, M.; Müller-Loennies, S.; Trusch, M.; Schmidt, B.; Schlüter, H.; Heeren, J.; Lübke, T.; Saftig, P.; Braulke, T. (2012): Mannose 6 dephosphorylation of lysosomal proteins mediated by Acid phosphatases acp2 and acp5 Molecular and cellular biology,32:(4): 774-782.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2529586Kollmann, K.; Damme, M.; Markmann, S.; Morelle, W.; Schweizer, M.; Hermans-Borgmeyer, I.; Rochert, A. K.; Pohl, S.; Lübke, T.; Michalski, J. - C.; Kakela, R.; Walkley, S. U.; Braulke, T. (2012): Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' mice Brain,135:(9): 2661-2675.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2494022Kowalewski, B.; Lamanna, W. C.; Lawrence, R.; Damme, M.; Padva, M.; Stroobants, S.; Kalus, I.; Frese, M. - A.; Lübke, T.; Lüllmann-Rauch, R.; D'Hooge, R.; Esko, J. D.; Dierks, T. (2012): Arylsulfatase G Inactivation Causes Loss of Heparan Sulfate 3-O-Sulfatase Activity and Mucopolysaccharidosis in Mice Proc. Natl. Acad. Sci. USA,109:(26): 10310-10315.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940515Damme, M.; Stroobants, S.; Walkley, S. U.; Lüllmann-Rauch, R.; D'Hooge, R.; Fogh, J.; Saftig, P.; Lübke, T.; Blanz, J. (2011): Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in alpha-mannosidosis Journal of Neuropathology & Experimental Neurology,70:(1): 83-94.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2352585Savalas, L. R.; Gasnier, B.; Damme, M.; Lübke, T.; Wrocklage, C.; Debacker, C.; Jezeqou, A.; Reinheckel, T.; Hasilik, A.; Saftig, P.; Schröder, B. (2011): Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L. Biochemical Journal,436:(1): 113-121.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902203Damme, M.; Morelle, W.; Schmidt, B.; Andersson, C.; Fogh, J.; Michalski, J. - C.; Lübke, T. (2010): Impaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis. Molecular and Cellular Biology,30:(1): 273-283.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Dissertation | PUB-ID: 2352701Damme, M. (2009): Zellbiologische Untersuchung α-Mannosidase-defizienter und Enzym-behandelter Mäuse.PUB | Download (ext.)
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902143Schieweck, O.; Damme, M.; Schröder, B.; Hasilik, A.; Schmidt, B.; Lübke, T. (2009): NCU-G1 is a highly glycosylated integral membrane protein of the lysosome. Biochemical Journal,422:(1): 83-90.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940533Kollmann, K.; Damme, M.; Deuschl, F.; Kahle, J.; D'Hooge, R.; Lüllmann-Rauch, R.; Lübke, T. (2009): Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1 Febs Journal,276:(5): 1356-1369.PUB | DOI | WoS | PubMed | Europe PMC