14 Publikationen
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904124Kruszewski, Katharina, Luellmann-Rauch, Renate, Dierks, Thomas, Bartsch, Udo, and Damme, Markus. “Degeneration of Photoreceptor Cells in Arylsulfatase G-Deficient Mice”. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 57.3 (2016): 1120-1131.PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2905616Wolf, Heike, Damme, Markus, Stroobants, Stijn, D'Hooge, Rudi, Beck, Hans Christian, Hermans-Borgmeyer, Irm, Lüllmann-Rauch, Renate, Dierks, Thomas, and Lübke, Torben. “A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease”. Disease Models & Mechanisms 9.9 (2016): 1015-1028.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2709463Kowalewski, Björn, Heimann, Peter, Ortkras, Theresa, Lüllmann-Rauch, Renate, Sawada, Tomo, Walkley, Steven U, Dierks, Thomas, and Damme, Markus. “Ataxia is the major neuropathological finding in Arylsulfatase G deficient mice: Similarities and dissimilarities to Sanfilippo disease (Mucopolysaccharidosis type III)”. Human Molecular Genetics 24.7 (2015): 1856-1868.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2658538Kong, Xiang Yi, Nesset, Cecilie K., Damme, Markus, Loeberg, Else-Marit, Lübke, Torben, Maehlen, Jan, Andersson, Kristin B., Roos, Norbert, Thoresen, G. Hege, Rustan, Arild C., Kase, Eili T., and Eskild, Winnie. “Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells”. Disease Models & Mechanisms 7.3 (2014): 351-362.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2484642Thelen, Melanie, Damme, Markus, Schweizer, Michaela, Hagel, Christian, Wong, Andrew, Cooper, Jonathan D., Braulke, Thomas, and Galliciotti, Giovanna. “Disruption of the Autophagy-Lysosome Pathway is Involved in Neuropathology of the nclf Mouse Model of Neuronal Ceroid Lipofuscinosis”. PLOS ONE 7.4 (2012): e35493.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471754Makrypidi, Georgia, Damme, Markus, Müller-Loennies, Sven, Trusch, Maria, Schmidt, Bernhard, Schlüter, Hartmut, Heeren, Joerg, Lübke, Torben, Saftig, Paul, and Braulke, Thomas. “Mannose 6 dephosphorylation of lysosomal proteins mediated by Acid phosphatases acp2 and acp5”. Molecular and cellular biology 32.4 (2012): 774-782.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2529586Kollmann, K, Damme, Markus, Markmann, S, Morelle, W, Schweizer, M, Hermans-Borgmeyer, I, Rochert, A K, Pohl, S, Lübke, Torben, Michalski, J-C, Kakela, R, Walkley, S U, and Braulke, T. “Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' mice”. Brain 135.9 (2012): 2661-2675.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2494022Kowalewski, Björn, Lamanna, William Christopher, Lawrence, Roger, Damme, Markus, Padva, Michael, Stroobants, Stijn, Kalus, Ina, Frese, Marc-André, Lübke, Torben, Lüllmann-Rauch, Renate, D'Hooge, Rudi, Esko, Jeffrey D, and Dierks, Thomas. “Arylsulfatase G Inactivation Causes Loss of Heparan Sulfate 3-O-Sulfatase Activity and Mucopolysaccharidosis in Mice”. Proc. Natl. Acad. Sci. USA 109.26 (2012): 10310-10315.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940515Damme, Markus, Stroobants, Stijn, Walkley, Steven U., Lüllmann-Rauch, Renate, D'Hooge, Rudi, Fogh, Jens, Saftig, Paul, Lübke, Torben, and Blanz, Judith. “Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in alpha-mannosidosis”. Journal of Neuropathology & Experimental Neurology 70.1 (2011): 83-94.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2352585Savalas, LR, Gasnier, B, Damme, Markus, Lübke, Torben, Wrocklage, C, Debacker, C, Jezeqou, A, Reinheckel, T, Hasilik, A, Saftig, P, and Schröder, Bernd. “Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L.”. Biochemical Journal 436.1 (2011): 113-121.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902203Damme, Markus, Morelle, Willy, Schmidt, Bernhard, Andersson, Claes, Fogh, Jens, Michalski, Jean-Claude, and Lübke, Torben. “Impaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis.”. Molecular and Cellular Biology 30.1 (2010): 273-283.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Dissertation | PUB-ID: 2352701Damme, Markus. Zellbiologische Untersuchung α-Mannosidase-defizienter und Enzym-behandelter Mäuse. 2009.PUB | Download (ext.)
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902143Schieweck, Oliver, Damme, Markus, Schröder, Bernd, Hasilik, Andrey, Schmidt, Bernhard, and Lübke, Torben. “NCU-G1 is a highly glycosylated integral membrane protein of the lysosome.”. Biochemical Journal 422.1 (2009): 83-90.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940533Kollmann, Katrin, Damme, Markus, Deuschl, Florian, Kahle, Jörg, D'Hooge, Rudi, Lüllmann-Rauch, Renate, and Lübke, Torben. “Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1”. Febs Journal 276.5 (2009): 1356-1369.PUB | DOI | WoS | PubMed | Europe PMC