PUB - Publikationen an der Universität Bielefeld

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• [32]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617209

  J. Schroder, et al., “Novel heterocyclic inhibitors of matrix metalloproteinases: three 6H-1,3,4-thiadiazines”, ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, vol. 57, 2001, pp. 593-596.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [31]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616195

  J. Schröder, et al., “Structure-based design and synthesis of potent matrix metalloproteinase inhibitors derived from a 6H-1,3,4-thiadiazine scaffold”, JOURNAL OF MEDICINAL CHEMISTRY, vol. 44, 2001, pp. 3231-3243.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [30]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1624672

  D. Krumme, H. Wenzel, and H. Tschesche, “Hydroxamate derivatives of substrate-analogous peptides containing aminomalonic acid are potent inhibitors of matrix metalloproteinases”, FEBS LETTERS, vol. 436, 1998, pp. 209-212.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [29]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628000

  T. Brinkmann, et al., “Strong crossreaction of human anti-aprotinin antibodies from heart transplant patient with [Arg(15)]aprotinin”, IMMUNOPHARMACOLOGY, vol. 35, 1997, pp. 221-228.

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• [28]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641415

  Y.T. WACHTFOGEL, et al., “SELECTIVE KALLIKREIN INHIBITORS ALTER HUMAN NEUTROPHIL ELASTASE RELEASE DURING EXTRACORPOREAL-CIRCULATION”, AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, vol. 268, 1995, pp. H1352-H1357.

  PUB | DOI | WoS
   
• [27]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1642944

  C. GROEGER, H. Wenzel, and H. Tschesche, “BPTI BACKBONE VARIANTS AND IMPLICATIONS FOR INHIBITORY ACTIVITY”, INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, vol. 44, 1994, pp. 166-172.

  PUB | WoS | PubMed | Europe PMC
   
• [26]
  

  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1645607

  C. GROEGER, H. Wenzel, and H. Tschesche, “THE IMPORTANCE OF THE RIGIDITY OF THE PEPTIDE BACKBONE FOR THE INHIBITORY PROPERTIES OF BPTI DEMONSTRATED BY SEMISYNTHETIC STRUCTURAL VARIANTS”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, vol. 32, 1993, pp. 898-900.

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• [25]
  

  1991 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1629600

  H. Tschesche, C. Groeger, and H. Wenzel, “ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN”, Emerg Med J, BIOMEDICA BIOCHIMICA ACTA, vol. 50, AKADEMIE VERLAG GMBH, 1991, pp.S175-S180.

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• [24]
  

  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1649242

  C. GROEGER, H. Wenzel, and H. Tschesche, “CHEMICAL SEMISYNTHESIS OF APROTININ HOMOLOGS AND DERIVATIVES MUTATED IN P' POSITIONS”, JOURNAL OF PROTEIN CHEMISTRY, vol. 10, 1991, pp. 527-533.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [23]
  

  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1649962

  C. GROEGER, H. Wenzel, and H. Tschesche, “ENZYMATIC SEMISYNTHESIS OF APROTININ HOMOLOGS MUTATED IN P' POSITIONS”, JOURNAL OF PROTEIN CHEMISTRY, vol. 10, 1991, pp. 245-251.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [22]
  

  1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1650922

  H. Wenzel, et al., “ACTIVATION OF THE HUMAN-LEUKOCYTE PROTEINASES ELASTASE AND CATHEPSIN-G BY VARIOUS SURFACTANTS”, BIOLOGICAL CHEMISTRY HOPPE-SEYLER, vol. 371, 1990, pp. 721-724.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [21]
  

  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1652842

  A. MEHLICH, et al., “SEMISYNTHETIC APROTININ DERIVATIVES WITH SPECIFIC ALTERATIONS AT THE REACTIVE-SITE PEPTIDE-BOND CAN BE USED TO STUDY STRUCTURE-FUNCTION-RELATIONSHIPS”, BIOCHIMICA ET BIOPHYSICA ACTA, vol. 996, 1989, pp. 23-29.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [20]
  

  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1652670

  J. SIEKMANN, et al., “IMMUNOLOGICAL CHARACTERIZATION OF NATURAL AND SEMISYNTHETIC APROTININ VARIANTS”, BIOLOGICAL CHEMISTRY HOPPE-SEYLER, vol. 370, 1989, pp. 677-682.

  PUB | DOI | WoS
   
• [19]
  

  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653324

  J. BECKMANN, et al., “SEMISYNTHESIS OF ARG-15-APROTININ, GLU-15-APROTININ, MET-15-APROTININ, AND NLE15-APROTININ INVOLVING ENZYMATIC PEPTIDE-BOND RESYNTHESIS”, JOURNAL OF PROTEIN CHEMISTRY, vol. 8, 1989, pp. 101-113.

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• [18]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653441

  A. MEHLICH, et al., “APROTININ DERIVATIVES WITH CHROMOPHORIC LEAVING GROUPS CAN BE USED AS HIGHLY SELECTIVE ACTIVE-SITE TITRANTS FOR SERINE PROTEINASES AND PERMIT THE DETERMINATION OF KINETIC CONSTANTS OF ENZYME-INHIBITOR COMPLEXES”, BIOCHIMICA ET BIOPHYSICA ACTA, vol. 957, 1988, pp. 420-429.

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• [17]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653768

  J. BECKMANN, et al., “PREPARATION OF CHEMICALLY MUTATED APROTININ HOMOLOGS BY SEMISYNTHESIS - P1 SUBSTITUTIONS CHANGE INHIBITORY SPECIFICITY”, EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 176, 1988, pp. 675-682.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [16]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654061

  E. SCHNABEL, et al., “ENZYMATIC RESYNTHESIS OF THE REACTIVE SITE BOND IN THE MODIFIED APROTININ DERIVATIVES [SECO-15/16]APROTININ AND [DI-SECO-15/16,39/40]APROTININ”, BIOLOGICAL CHEMISTRY HOPPE-SEYLER, vol. 369, 1988, pp. 461-468.

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• [15]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654439

  J. SIEKMANN, et al., “CHARACTERIZATION AND SEQUENCE DETERMINATION OF 6 APROTININ HOMOLOGS FROM BOVINE LUNGS”, BIOLOGICAL CHEMISTRY HOPPE-SEYLER, vol. 369, 1988, pp. 157-164.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [14]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653623

  J. SIEKMANN, et al., “THE PH-DEPENDENCE OF THE EQUILIBRIUM-CONSTANT KHYD FOR THE HYDROLYSIS OF THE LYS15-ALA16 REACTIVE-SITE PEPTIDE-BOND IN BOVINE PANCREATIC TRYPSIN-INHIBITOR (APROTININ)”, JOURNAL OF PROTEIN CHEMISTRY, vol. 7, 1988, pp. 633-640.

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• [13]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948524

  J. Beckmann, et al., “Semisynthetic inhibitors of human leukocyte elastase and their protective effect on lung elastin degradation in vitro”, Adv Exp Med Biol, vol. 240, 1988, pp. 107-114.

  PUB | PubMed | Europe PMC
   
• [12]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1655390

  H. Tschesche, et al., “SEMISYNTHETIC ENGINEERING OF PROTEINASE-INHIBITOR HOMOLOGS”, BIOCHIMICA ET BIOPHYSICA ACTA, vol. 913, 1987, pp. 97-101.

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• [11]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1655547

  C.F. SCOTT, et al., “KINETICS OF INHIBITION OF HUMAN-PLASMA KALLIKREIN BY A SITE-SPECIFIC MODIFIED INHIBITOR ARG15-APROTININ - EVALUATION USING A MICROPLATE SYSTEM AND COMPARISON WITH OTHER PROTEASES”, BLOOD, vol. 69, 1987, pp. 1431-1436.

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• [10]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654700

  J. SIEKMANN, et al., “PYROGLUTAMYL-APROTININ, A NEW APROTININ HOMOLOG FROM BOVINE LUNGS - ISOLATION, PROPERTIES, SEQUENCE-ANALYSIS AND CHARACTERIZATION USING HYDROGEN NUCLEAR MAGNETIC-RESONANCE IN SOLUTION”, BIOLOGICAL CHEMISTRY HOPPE-SEYLER, vol. 368, 1987, pp. 1589-1596.

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• [9]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654832

  O.H. HANKOVSZKY, et al., “NEW NITROXIDE REAGENTS FOR THE SELECTIVE SPIN-LABELING AT THE GUANIDINO MOIETY OF ARGININE RESIDUES IN PEPTIDES AND PROTEINS”, BIOCHIMICA ET BIOPHYSICA ACTA, vol. 916, 1987, pp. 152-155.

  PUB | DOI | WoS
   
• [8]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1655347

  H. SCHWARZ, et al., “STABILITY STUDIES ON DERIVATIVES OF THE BOVINE PANCREATIC TRYPSIN-INHIBITOR”, BIOCHEMISTRY, vol. 26, 1987, pp. 3544-3551.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [7]
  

  1984 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1658517

  W. BODE, et al., “THE REFINED 2.2-A (0.22-NM) X-RAY CRYSTAL-STRUCTURE OF THE TERNARY COMPLEX FORMED BY BOVINE TRYPSINOGEN, VALINE-VALINE AND THE ARG15 ANALOG OF BOVINE PANCREATIC TRYPSIN-INHIBITOR”, EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 144, 1984, pp. 185-190.

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• [6]
  

  1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660972

  S. ENGELBRECHT, et al., “SEPARATION OF THE HUMAN-LEUKOCYTE ENZYMES ALANINE AMINOPEPTIDASE, CATHEPSIN-G, COLLAGENASE, ELASTASE AND MYELOPEROXIDASE”, HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, vol. 363, 1982, pp. 305-316.

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• [5]
  

  1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660931

  H. Wenzel, et al., “COMPLEX-FORMATION OF GUANIDINATED BOVINE TRYPSIN-INHIBITOR (KUNITZ) WITH TRYPSIN, CHYMOTRYPSIN AND TRYPSINOGEN AS STUDIED BY THE SPIN-LABEL TECHNIQUE”, FEBS LETTERS, vol. 140, 1982, pp. 53-57.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [4]
  

  1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660955

  H. BURKHARDT, et al., “INHIBITION OF RHEUMATOID CARTILAGE DEGRADATION - A BIOMECHANICAL ASSAY FOR POTENTIAL ANTI-RHEUMATIC DRUGS”, AKTUELLE RHEUMATOLOGIE, vol. 7, 1982, pp. 60-62.

  PUB | DOI | WoS
   
• [3]
  

  1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1661716

  H. Wenzel and H. Tschesche, “CHEMICAL MUTATION BY AMINO-ACID EXCHANGE IN THE REACTIVE SITE OF A PROTEINASE-INHIBITOR AND ALTERATION OF ITS INHIBITOR SPECIFITY”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, vol. 20, 1981, pp. 295-296.

  PUB | DOI | WoS
   
• [2]
  

  1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1661674

  H. Wenzel and H. Tschesche, “CLEAVAGE OF PEPTIDE-4-NITROANILIDE SUBSTRATES WITH VARYING CHAIN-LENGTH BY HUMAN-LEUKOCYTE ELASTASE”, HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, vol. 362, 1981, pp. 829-831.

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• [1]
  

  1980 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1662186

  H. Wenzel, et al., “SYNTHESIS AND ANALYTICAL USE OF 3-CARBOXYPROPIONYL-ALANYL-ALANYL-VALINE-4-NITROANILIDE - A SPECIFIC SUBSTRATE FOR HUMAN-LEUKOCYTE ELASTASE”, HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, vol. 361, 1980, pp. 1413-1416.

  PUB | DOI | WoS | PubMed | Europe PMC