PUB - Publikationen an der Universität Bielefeld

Alle markieren

• [32]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617209

  Schroder J, Wenzel H, Stammler H-G, Stammler A, Neumann B, Tschesche H. Novel heterocyclic inhibitors of matrix metalloproteinases: three 6H-1,3,4-thiadiazines. ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS. 2001;57(5):593-596.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [31]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616195

  Schröder J, Henke A, Wenzel H, et al. Structure-based design and synthesis of potent matrix metalloproteinase inhibitors derived from a 6H-1,3,4-thiadiazine scaffold. JOURNAL OF MEDICINAL CHEMISTRY. 2001;44(20):3231-3243.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [30]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1624672

  Krumme D, Wenzel H, Tschesche H. Hydroxamate derivatives of substrate-analogous peptides containing aminomalonic acid are potent inhibitors of matrix metalloproteinases. FEBS LETTERS. 1998;436(2):209-212.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [29]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628000

  Brinkmann T, Korfer R, Wenzel H, Tschesche H, Kleesiek K. Strong crossreaction of human anti-aprotinin antibodies from heart transplant patient with [Arg(15)]aprotinin. IMMUNOPHARMACOLOGY. 1997;35(3):221-228.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [28]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641415

  WACHTFOGEL YT, HACK CE, NUIJENS JH, et al. SELECTIVE KALLIKREIN INHIBITORS ALTER HUMAN NEUTROPHIL ELASTASE RELEASE DURING EXTRACORPOREAL-CIRCULATION. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 1995;268(3):H1352-H1357.

  PUB | DOI | WoS
   
• [27]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1642944

  GROEGER C, Wenzel H, Tschesche H. BPTI BACKBONE VARIANTS AND IMPLICATIONS FOR INHIBITORY ACTIVITY. INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH. 1994;44(2):166-172.

  PUB | WoS | PubMed | Europe PMC
   
• [26]
  

  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1645607

  GROEGER C, Wenzel H, Tschesche H. THE IMPORTANCE OF THE RIGIDITY OF THE PEPTIDE BACKBONE FOR THE INHIBITORY PROPERTIES OF BPTI DEMONSTRATED BY SEMISYNTHETIC STRUCTURAL VARIANTS. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH. 1993;32(6):898-900.

  PUB | DOI | WoS
   
• [25]
  

  1991 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1629600

  Tschesche H, Groeger C, Wenzel H. ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN. In: Emerg Med J. BIOMEDICA BIOCHIMICA ACTA. Vol 50. AKADEMIE VERLAG GMBH; 1991: S175-S180.

  PUB | WoS | PubMed | Europe PMC
   
• [24]
  

  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1649242

  GROEGER C, Wenzel H, Tschesche H. CHEMICAL SEMISYNTHESIS OF APROTININ HOMOLOGS AND DERIVATIVES MUTATED IN P' POSITIONS. JOURNAL OF PROTEIN CHEMISTRY. 1991;10(5):527-533.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [23]
  

  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1649962

  GROEGER C, Wenzel H, Tschesche H. ENZYMATIC SEMISYNTHESIS OF APROTININ HOMOLOGS MUTATED IN P' POSITIONS. JOURNAL OF PROTEIN CHEMISTRY. 1991;10(2):245-251.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [22]
  

  1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1650922

  Wenzel H, FELDMANN A, ENGELBRECHT S, Tschesche H. ACTIVATION OF THE HUMAN-LEUKOCYTE PROTEINASES ELASTASE AND CATHEPSIN-G BY VARIOUS SURFACTANTS. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 1990;371(2):721-724.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [21]
  

  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1652842

  MEHLICH A, BECKMANN J, Wenzel H, Tschesche H. SEMISYNTHETIC APROTININ DERIVATIVES WITH SPECIFIC ALTERATIONS AT THE REACTIVE-SITE PEPTIDE-BOND CAN BE USED TO STUDY STRUCTURE-FUNCTION-RELATIONSHIPS. BIOCHIMICA ET BIOPHYSICA ACTA. 1989;996(1-2):23-29.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [20]
  

  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1652670

  SIEKMANN J, BECKMANN J, MEHLICH A, et al. IMMUNOLOGICAL CHARACTERIZATION OF NATURAL AND SEMISYNTHETIC APROTININ VARIANTS. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 1989;370(2):677-682.

  PUB | DOI | WoS
   
• [19]
  

  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653324

  BECKMANN J, MEHLICH A, SCHRODER W, Wenzel H, Tschesche H. SEMISYNTHESIS OF ARG-15-APROTININ, GLU-15-APROTININ, MET-15-APROTININ, AND NLE15-APROTININ INVOLVING ENZYMATIC PEPTIDE-BOND RESYNTHESIS. JOURNAL OF PROTEIN CHEMISTRY. 1989;8(1):101-113.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [18]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653441

  MEHLICH A, BECKMANN J, Wenzel H, Tschesche H. APROTININ DERIVATIVES WITH CHROMOPHORIC LEAVING GROUPS CAN BE USED AS HIGHLY SELECTIVE ACTIVE-SITE TITRANTS FOR SERINE PROTEINASES AND PERMIT THE DETERMINATION OF KINETIC CONSTANTS OF ENZYME-INHIBITOR COMPLEXES. BIOCHIMICA ET BIOPHYSICA ACTA. 1988;957(3):420-429.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [17]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653768

  BECKMANN J, MEHLICH A, SCHRODER W, Wenzel H, Tschesche H. PREPARATION OF CHEMICALLY MUTATED APROTININ HOMOLOGS BY SEMISYNTHESIS - P1 SUBSTITUTIONS CHANGE INHIBITORY SPECIFICITY. EUROPEAN JOURNAL OF BIOCHEMISTRY. 1988;176(3):675-682.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [16]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654061

  SCHNABEL E, REINHARDT G, SCHRODER W, Tschesche H, Wenzel H, MEHLICH A. ENZYMATIC RESYNTHESIS OF THE REACTIVE SITE BOND IN THE MODIFIED APROTININ DERIVATIVES [SECO-15/16]APROTININ AND [DI-SECO-15/16,39/40]APROTININ. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 1988;369(1):461-468.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [15]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654439

  SIEKMANN J, Wenzel H, SCHRODER W, Tschesche H. CHARACTERIZATION AND SEQUENCE DETERMINATION OF 6 APROTININ HOMOLOGS FROM BOVINE LUNGS. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 1988;369(1):157-164.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [14]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653623

  SIEKMANN J, Wenzel H, MATUSZAK E, VONGOLDAMMER E, Tschesche H. THE PH-DEPENDENCE OF THE EQUILIBRIUM-CONSTANT KHYD FOR THE HYDROLYSIS OF THE LYS15-ALA16 REACTIVE-SITE PEPTIDE-BOND IN BOVINE PANCREATIC TRYPSIN-INHIBITOR (APROTININ). JOURNAL OF PROTEIN CHEMISTRY. 1988;7(5):633-640.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [13]
  

  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948524

  Beckmann J, Mehlich A, Wenzel H, Tschesche H. Semisynthetic inhibitors of human leukocyte elastase and their protective effect on lung elastin degradation in vitro. Adv Exp Med Biol. 1988;240:107-114.

  PUB | PubMed | Europe PMC
   
• [12]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1655390

  Tschesche H, BECKMANN J, MEHLICH A, SCHNABEL E, TRUSCHEIT E, Wenzel H. SEMISYNTHETIC ENGINEERING OF PROTEINASE-INHIBITOR HOMOLOGS. BIOCHIMICA ET BIOPHYSICA ACTA. 1987;913(1):97-101.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [11]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1655547

  SCOTT CF, Wenzel H, Tschesche H, COLMAN RW. KINETICS OF INHIBITION OF HUMAN-PLASMA KALLIKREIN BY A SITE-SPECIFIC MODIFIED INHIBITOR ARG15-APROTININ - EVALUATION USING A MICROPLATE SYSTEM AND COMPARISON WITH OTHER PROTEASES. BLOOD. 1987;69(5):1431-1436.

  PUB | WoS | PubMed | Europe PMC
   
• [10]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654700

  SIEKMANN J, Wenzel H, SCHRODER W, et al. PYROGLUTAMYL-APROTININ, A NEW APROTININ HOMOLOG FROM BOVINE LUNGS - ISOLATION, PROPERTIES, SEQUENCE-ANALYSIS AND CHARACTERIZATION USING HYDROGEN NUCLEAR MAGNETIC-RESONANCE IN SOLUTION. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 1987;368(2):1589-1596.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [9]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654832

  HANKOVSZKY OH, HIDEG K, VONGOLDAMMER E, et al. NEW NITROXIDE REAGENTS FOR THE SELECTIVE SPIN-LABELING AT THE GUANIDINO MOIETY OF ARGININE RESIDUES IN PEPTIDES AND PROTEINS. BIOCHIMICA ET BIOPHYSICA ACTA. 1987;916(1):152-155.

  PUB | DOI | WoS
   
• [8]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1655347

  SCHWARZ H, HINZ HJ, MEHLICH A, Tschesche H, Wenzel H. STABILITY STUDIES ON DERIVATIVES OF THE BOVINE PANCREATIC TRYPSIN-INHIBITOR. BIOCHEMISTRY. 1987;26(12):3544-3551.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [7]
  

  1984 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1658517

  BODE W, WALTER J, HUBER R, Wenzel H, Tschesche H. THE REFINED 2.2-A (0.22-NM) X-RAY CRYSTAL-STRUCTURE OF THE TERNARY COMPLEX FORMED BY BOVINE TRYPSINOGEN, VALINE-VALINE AND THE ARG15 ANALOG OF BOVINE PANCREATIC TRYPSIN-INHIBITOR. EUROPEAN JOURNAL OF BIOCHEMISTRY. 1984;144(1):185-190.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [6]
  

  1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660972

  ENGELBRECHT S, PIEPER E, MACARTNEY HW, RAUTENBERG W, Wenzel H, Tschesche H. SEPARATION OF THE HUMAN-LEUKOCYTE ENZYMES ALANINE AMINOPEPTIDASE, CATHEPSIN-G, COLLAGENASE, ELASTASE AND MYELOPEROXIDASE. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 1982;363(1):305-316.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [5]
  

  1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660931

  Wenzel H, Tschesche H, VONGOLDAMMER E, NETZELMANN U. COMPLEX-FORMATION OF GUANIDINATED BOVINE TRYPSIN-INHIBITOR (KUNITZ) WITH TRYPSIN, CHYMOTRYPSIN AND TRYPSINOGEN AS STUDIED BY THE SPIN-LABEL TECHNIQUE. FEBS LETTERS. 1982;140(1):53-57.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [4]
  

  1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660955

  BURKHARDT H, MENNINGER H, BERNER W, et al. INHIBITION OF RHEUMATOID CARTILAGE DEGRADATION - A BIOMECHANICAL ASSAY FOR POTENTIAL ANTI-RHEUMATIC DRUGS. AKTUELLE RHEUMATOLOGIE. 1982;7(02):60-62.

  PUB | DOI | WoS
   
• [3]
  

  1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1661716

  Wenzel H, Tschesche H. CHEMICAL MUTATION BY AMINO-ACID EXCHANGE IN THE REACTIVE SITE OF A PROTEINASE-INHIBITOR AND ALTERATION OF ITS INHIBITOR SPECIFITY. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH. 1981;20(3):295-296.

  PUB | DOI | WoS
   
• [2]
  

  1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1661674

  Wenzel H, Tschesche H. CLEAVAGE OF PEPTIDE-4-NITROANILIDE SUBSTRATES WITH VARYING CHAIN-LENGTH BY HUMAN-LEUKOCYTE ELASTASE. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 1981;362(6):829-831.

  PUB | WoS | PubMed | Europe PMC
   
• [1]
  

  1980 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1662186

  Wenzel H, ENGELBRECHT S, REICH H, MONDRY W, Tschesche H. SYNTHESIS AND ANALYTICAL USE OF 3-CARBOXYPROPIONYL-ALANYL-ALANYL-VALINE-4-NITROANILIDE - A SPECIFIC SUBSTRATE FOR HUMAN-LEUKOCYTE ELASTASE. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 1980;361(2):1413-1416.

  PUB | DOI | WoS | PubMed | Europe PMC