PUB - Publikationen an der Universität Bielefeld

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• [193]
  

  2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2444963

  Lauhio, A., Saikku, P., Salo, T., Tschesche, H., Lähdevirta, J., Sorsa, T.: Combination treatment in Chlamydia-triggered reactive arthritis: Comment on the article by Carter et al. Arthritis & Rheumatism. 63, 305-307 (2011).

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• [192]
  

  2011 | Herausgeber*in Sammelwerk | Veröffentlicht | PUB-ID: 2445257

  Tschesche, H. ed: Methods in Protein Biochemistry. DeGruyter, Berlin (2011).

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• [191]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1630960

  Kapischke, M., Fischer, T., Tiessen, K., Tschesche, H., Bruch, H.-P., Kalthoff, H., Kruse, M.-L.: Characterisation of a novel matrix metalloproteinase inhibitor on pancreatic adenocarcinoma cells in vitro and in an orthotopic pancreatic cancer model in vivo. INTERNATIONAL JOURNAL OF ONCOLOGY. 32, 273-282 (2008).

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• [190]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1595220

  Maskos, K., Lang, R., Tschesche, H., Bode, W.: Flexibility and variability of TIMP binding: X-ray structure of the complex between collagenase-3/MMP-13 and TIMP-2. JOURNAL OF MOLECULAR BIOLOGY. 366, 1222-1231 (2007).

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• [189]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631936

  Kubben, F.J.G.M., Sier, C.F.M., Hawinkels, L.J.A.C., Tschesche, H., van Duijn, W., Zuidwijk, K., van der Reijden, J.J., Hanemaaijer, R., Griffioen, G., Lamers, C.B.H.W., Verspaget, H.W.: Clinical evidence for a protective role of lipocalin-2 against MDAP-9 autodegradation and the impact for gastric cancer. EUROPEAN JOURNAL OF CANCER. 43, 1869-1876 (2007).

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• [188]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1601428

  Campestre, C., Agamennone, M., Tortorella, P., Preziuso, S., Biasone, A., Gavuzzo, E., Pochetti, G., Mazza, F., Hiller, O., Tschesche, H., Consalvi, V., Gallina, C.: N-hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: Mode of binding in a complex with MMP-8. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 16, 20-24 (2006).

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• [187]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1600157

  Pochetti, G., Gavuzzo, E., Campestre, C., Agamennone, M., Tortorella, P., Consalvi, V., Gallina, C., Hiller, O., Tschesche, H., Tucker, P.A., Mazza, F.: Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates. JOURNAL OF MEDICINAL CHEMISTRY. 49, 923-931 (2006).

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• [186]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1605178

  Beck, V., Herold, H., Benge, A., Luber, B., Hutzler, P., Tschesche, H., Kessler, H., Schmitt, M., Geppert, H.G., Reuning, U.: ADAM15 decreases integrin alpha v beta 3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 37, 590-603 (2005).

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• [185]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608079

  Diehl, P., Hantke, B., Hennig, M., Tschesche, H., Mittelmeier, W., Schmitt, M., Muehlenweg, B.: Protein expression of MMP-13, uPA, and PAI-1 in pseudocapsular and interface tissue around implants of loose artificial hip joints and in osteoarthritis. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 13, 711-715 (2004).

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• [184]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1607873

  Naib-Majani, W., Eltohami, I., Wernert, N., Watts, W., Tschesche, H., Pleyer, U., Breipohl, W.: Distribution of extracellular matrix proteins in pterygia: an immunohistochemical study. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY. 242, 332-338 (2004).

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• [183]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608728

  Hurst, D.R., Schwartz, M.A., Ghaffari, M.A., Jin, Y.H., Tschesche, H., Fields, G.B., Sang, Q.X.A.: Catalytic- and ecto-domains of membrane type 1-matrix metalloproteinase have similar inhibition profiles but distinct endopeptidase activities. BIOCHEMICAL JOURNAL. 377, 775-779 (2004).

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• [182]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1607326

  Kang, T.B., Tschesche, H., Sang, Q.X.A.: Evidence for disulfide involvement in the regulation of intramolecular autolytic processing by human adamalysin19/ADAM19. EXPERIMENTAL CELL RESEARCH. 298, 285-295 (2004).

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• [181]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609552

  Stute, J., Pourmotabbed, T., Tschesche, H.: Kinetic analysis of the binding of hemopexin-like domain of gelatinase B cloned and expressed in Pichia pastoris to tissue inhibitor of metalloproteinases-1. JOURNAL OF PROTEIN CHEMISTRY. 22, 509-514 (2003).

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• [180]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1611184

  Schmaldienst, S., Oberpichler, A., Tschesche, H., Horl, W.H.: Angiogenin: A novel inhibitor of neutrophil lactoferrin release during extracorporeal circulation. KIDNEY & BLOOD PRESSURE RESEARCH. 26, 107-112 (2003).

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• [179]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1610443

  Hantke, B., Harbeck, N., Schmalfeldt, B., Claes, I., Hiller, O., Luther, M.O., Welk, A., Kuhn, W., Schmitt, M., Tschesche, H., Muehlenweg, B.: Clinical relevance of matrix metalloproteinase-13 determined with a new highly specific and sensitive ELISA in ascitic fluid of advanced ovarian carcinoma patients. BIOLOGICAL CHEMISTRY. 384, 1247-1251 (2003).

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• [178]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613692

  Aschi, M., Roccatano, D., Di Nola, A., Gallina, C., Gavuzzo, E., Pochetti, G., Pieper, M., Tschesche, H., Mazza, F.: Computational study of the catalytic domain of human neutrophil collagenase. Specific role of the S-3 and S '(3) subsites in the interaction with a phosphonate inhibitor. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN. 16, 213-225 (2002).

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• [177]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1614253

  Gioia, M., Fasciglione, G.F., Marini, S., D'Alessio, S., De Sanctis, G., Diekmann, O., Pieper, M., Politi, V., Tschesche, H., Coletta, M.: Modulation of the catalytic activity of neutrophil collagenase MMP-8 on bovine collagen I - Role of the activation cleavage and of the hemopexin-like domain. JOURNAL OF BIOLOGICAL CHEMISTRY. 277, 23123-23130 (2002).

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• [176]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1612891

  Mohan, S., Thompson, G.R., Amaar, Y.G., Hathaway, G., Tschesche, H., Baylink, D.J.: ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts. BIOCHEMISTRY. 41, 15394-15403 (2002).

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• [175]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1612930

  Kang, T.B., Park, H.I., Suh, Y., Zhao, Y.G., Tschesche, H., Sang, Q.X.A.: Autolytic processing at Glu(586)-Ser(587) within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activity. JOURNAL OF BIOLOGICAL CHEMISTRY. 277, 48514-48522 (2002).

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• [174]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1614644

  Krumme, D., Tschesche, H.: Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 12, 933-936 (2002).

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• [173]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1614790

  Kaur, K., Zhu, K.J., Whittemore, M.S., Petersen, R.L., Lichte, A., Tschesche, H., Pourmotabbed, T.: Identification of the active site of gelatinase B as the structural element sufficient for converting a protein to a metalloprotease. BIOCHEMISTRY. 41, 4789-4797 (2002).

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• [172]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613258

  Hantke, B., Lahmann, C., Venzke, K., Fischer, T., Kocourek, A., Windsor, L.J., Bergemann, J., Stab, F., Tschesche, H.: Influence of flavonoids and vitamins on the MMP- and TIMP-expression of human dermal fibroblasts after UVA irradiation. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES. 1, 826-833 (2002).

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• [171]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1615871

  Stratmann, B., Farr, M., Tschesche, H.: MMP-TIMP interaction depends on residue 2 in TIMP-4. FEBS LETTERS. 507, 285-287 (2001).

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• [170]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617925

  Schwettmann, L., Tschesche, H.: Cloning and expression in Pichia pastoris of metalloprotease domain of ADAM 9 catalytically active against fibronectin. PROTEIN EXPRESSION AND PURIFICATION. 21, 65-70 (2001).

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• [169]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617209

  Schroder, J., Wenzel, H., Stammler, H.-G., Stammler, A., Neumann, B., Tschesche, H.: Novel heterocyclic inhibitors of matrix metalloproteinases: three 6H-1,3,4-thiadiazines. ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS. 57, 593-596 (2001).

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• [168]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1615419

  Schnepel, J., Unger, J., Tschesche, H.: Recombinant cryptic human fibronectinase cleaves actin and myosin: Substrate specificity and possible role in muscular dystrophy. BIOLOGICAL CHEMISTRY. 382, 1707-1714 (2001).

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• [167]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616195

  Schröder, J., Henke, A., Wenzel, H., Brandstetter, H., Stammler, H.-G., Stammler, A., Pfeiffer, W.D., Tschesche, H.: Structure-based design and synthesis of potent matrix metalloproteinase inhibitors derived from a 6H-1,3,4-thiadiazine scaffold. JOURNAL OF MEDICINAL CHEMISTRY. 44, 3231-3243 (2001).

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• [166]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616669

  Stratmann, B., Farr, M., Tschesche, H.: Characterization of C-terminally truncated human tissue inhibitor of metalloproteinases-4 expressed in Pichia pastoris. BIOLOGICAL CHEMISTRY. 382, 987-991 (2001).

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• [165]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617227

  Winkler, M., Kemp, B., Oberpichler, A., Fischer, D.C., Tschesche, H., Rath, W.: Concentrations of matrix metalloproteinase 8 and 9 and tissue inhibitor of metalloproteinases-1 in the uterus during preterm delivery. GEBURTSHILFE UND FRAUENHEILKUNDE. 61, 200-204 (2001).

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• [164]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617481

  Tschesche, H., Zolzer, V., Triebel, S., Bartsch, S.: The human neutrophil lipocalin supports the allosteric activation of matrix metalloproteinases. EUROPEAN JOURNAL OF BIOCHEMISTRY. 268, 1918-1928 (2001).

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• [163]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616109

  Lang, R., Kocourek, A., Braun, M., Tschesche, H., Huber, R., Bode, W., Maskos, K.: Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 angstrom crystal structure. JOURNAL OF MOLECULAR BIOLOGY. 312, 731-742 (2001).

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• [162]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619051

  Gavuzzo, E., Pochetti, G., Mazza, F., Gallina, C., Gorini, B., D'Alessio, S., Pieper, M., Tschesche, H., Tucker, P.A.: Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: Implications for drug design. JOURNAL OF MEDICINAL CHEMISTRY. 43, 3377-3385 (2000).

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• [161]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619082

  Eberle, K., Oberpichler, A., Trantakis, C., Krupp, W., Knupfer, M., Tschesche, H., Seifert, V.: The expression of angiogenin in tissue samples of different brain tumours and cultured glioma cells. ANTICANCER RESEARCH. 20, 1679-1684 (2000).

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• [160]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619190

  Roderfeld, M., Buttner, F.H., Bartnik, E., Tschesche, H.: Expression of human membrane type 1 matrix metalloproteinase in Pichia pastoris. PROTEIN EXPRESSION AND PURIFICATION. 19, 369-374 (2000).

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• [159]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1618259

  Toth, M., Bernardo, M.M., Gervasi, D.C., Soloway, P.D., Wang, Z.P., Bigg, H.F., Overall, C.M., DeClerck, Y.A., Tschesche, H., Cher, M.L., Brown, S., Mobashery, S., Fridman, R.: Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (membrane type 1)-MMP-dependent activation of pro-MMP-2. JOURNAL OF BIOLOGICAL CHEMISTRY. 275, 41415-41423 (2000).

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• [158]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1618754

  Hiller, O., Lichte, A., Oberpichler, A., Kocourek, A., Tschesche, H.: Matrix metalloproteinases collagenase-2, macrophage elastase, collagenase-3, and membrane type 1-matrix metalloproteinase impair clotting by degradation of fibrinogen and factor XII. JOURNAL OF BIOLOGICAL CHEMISTRY. 275, 33008-33013 (2000).

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• [157]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1618893

  Farr, M., Strube, J., Geppert, H.G., Kocourek, A., Mahne, M., Tschesche, H.: Pregnancy-associated plasma protein-E (PAPP-E). BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION. 1493, 356-362 (2000).

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• [156]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619452

  Bachmeier, B.E., Nerlich, A.G., Boukamp, P., Lichtinghagen, R., Tschesche, H., Fritz, H., Fink, E.: Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases-1,-8, and-13 and of TIMP-1. BIOLOGICAL CHEMISTRY. 381, 509-516 (2000).

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• [155]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1620705

  Ottl, J., Gabriel, D., Murphy, G., Knauper, V., Tominaga, Y., Nagase, H., Kroger, M., Tschesche, H., Bode, W., Moroder, L.: Recognition and catabolism of synthetic heterotrimeric collagen peptides by matrix metalloproteinases. CHEMISTRY & BIOLOGY. 7, 119-132 (2000).

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• [154]
  

  2000 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1619582

  Tschesche, H., Lichte, A., Hiller, O., Oberpichler, A., Buttner, F.H., Bartnik, E.: Matrix metalloproteinases (MMP-8,-13, and-14) interact with the clotting system and degrade fibrinogen and factor XII (hagemann factor). CELLULAR PEPTIDASES IN IMMUNE FUNCTIONS AND DISEASES 2. 477, p. 217-228. KLUWER ACADEMIC / PLENUM PUBL (2000).

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• [153]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617697

  Schnepel, J., Tschesche, H.: The proteolytic activity of the recombinant cryptic human fibronectin type IV collagenase from E-coli expression. JOURNAL OF PROTEIN CHEMISTRY. 19, 685-692 (2000).

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• [152]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619122

  Price, B., Dennison, C., Tschesche, H., Elliott, E.: Neutrophil tissue inhibitor of matrix metalloproteinases-1 occurs in novel vesicles that do not fuse with the phagosome. JOURNAL OF BIOLOGICAL CHEMISTRY. 275, 28308-28315 (2000).

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• [151]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622839

  Coles, M., Diercks, T., Muehlenweg, B., Bartsch, S., Zolzer, V., Tschesche, H., Kessler, H.: The solution structure and dynamics of human neutrophil gelatinase-associated lipocalin. JOURNAL OF MOLECULAR BIOLOGY. 289, 139-157 (1999).

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• [150]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622935

  Farr, M., Pieper, M., Calvete, J., Tschesche, H.: The N-terminus of collagenase MMP-8 determines superactivity and inhibition: A relation of structure and function analyzed by biomolecular interaction analysis. BIOCHEMISTRY. 38, 7332-7338 (1999).

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• [149]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1623072

  Bode, W., Fernandez-Catalan, C., Tschesche, H., Grams, F., Nagase, H., Maskos, K.: Structural properties of matrix metalloproteinases. CELLULAR AND MOLECULAR LIFE SCIENCES. 55, 639-652 (1999).

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• [148]
  

  1999 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1622253

  Bode, W., Fernandez-Catalan, C., Grams, F., Gomis-Ruth, F.X., Nagase, H., Tschesche, H., Maskos, K.: Insights into MMP-TIMP interactions. INHIBITION OF MATRIX METALLOPROTEINASES: THERAPEUTIC APPLICATIONS. Annals of the New York Academy of Sciences. 878, p. 73-91. NEW YORK ACAD SCIENCES (1999).

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• [147]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1623206

  Winkler, M., Fischer, D.C., Ruck, P., Marx, T., Kaiserling, E., Oberpichler, A., Tschesche, H., Rath, W.: Parturition at term: parallel increases in interleukin-8 and proteinase concentrations and neutrophil count in the lower uterine segment. HUMAN REPRODUCTION. 14, 1096-1100 (1999).

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• [146]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622044

  Wilharm, E., Parry, M.A.A., Friebel, R., Tschesche, H., Matschiner, G., Sommerhoff, C.P., Jenne, D.E.: Generation of catalytically active granzyme K from Escherichia coli inclusion bodies and identification of efficient granzyme K inhibitors in human plasma. JOURNAL OF BIOLOGICAL CHEMISTRY. 274, 27331-27337 (1999).

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• [145]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622408

  Unger, J., Tschesche, H.: The proteolytic activity and cleavage specificity of fibronectin-gelatinase and fibronectin-lamininase. JOURNAL OF PROTEIN CHEMISTRY. 18, 403-411 (1999).

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• [144]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1623381

  Krumme, D., Tschesche, H.: Synthesis and reduction of endothiodipeptides containing malonic acid derivatives. TETRAHEDRON. 55, 3007-3018 (1999).

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• [143]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622495

  Winkler, M., Oberpichler, A., Tschesche, H., Ruck, P., Fischer, D.C., Rath, W.: Collagenolysis in the lower uterine segment during parturition at term: Correlations with stage of cervical dilatation and duration of labor. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 181, 153-158 (1999).

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• [142]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1625197

  Buttner, F.H., Hughes, C.E., Margerie, D., Lichte, A., Tschesche, H., Caterson, B., Bartnik, E.: Membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan substrate rAgg1(mut) at the 'aggrecanase' and the MMP sites - Characterization of MT1-MMP catabolic activities on the interglobular domain of aggrecan. BIOCHEMICAL JOURNAL. 333, 159-165 (1998).

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• [141]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1625636

  Jung, K., Laube, C., Lein, M., Lichtinghagen, R., Tschesche, H., Schnorr, D., Loening, S.A.: Kind of sample as preanalytical determinant of matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinase 2 in blood. CLINICAL CHEMISTRY. 44, 1060-1062 (1998).

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• [140]
  

  1998 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1624999

  Tschesche, H.: Bimolecular interaction of matrix metalloproteinases and their inhibitors TIMPS. J Protein Chem. JOURNAL OF PROTEIN CHEMISTRY. 17, p. 549-551. PLENUM PUBL CORP (1998).

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• [139]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1625271

  Li, H., Bauzon, D.E., Xu, X.Y., Tschesche, H., Cao, J., Sang, Q.X.A.: Immunological characterization of cell-surface and soluble forms of membrane type 1 matrix metalloproteinase in human breast cancer cells and in fibroblasts. MOLECULAR CARCINOGENESIS. 22, 84-94 (1998).

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• [138]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1624672

  Krumme, D., Wenzel, H., Tschesche, H.: Hydroxamate derivatives of substrate-analogous peptides containing aminomalonic acid are potent inhibitors of matrix metalloproteinases. FEBS LETTERS. 436, 209-212 (1998).

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• [137]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1624817

  Fernandez-Catalan, C., Bode, W., Huber, R., Turk, D., Calvete, J.J., Lichte, A., Tschesche, H., Maskos, K.: Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor. EMBO JOURNAL. 17, 5238-5248 (1998).

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  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626404

  Sepper, R., Konttinen, Y.T., Buo, L., Eklund, K.K., Lauhio, A., Sorsa, T., Tschesche, H., Aasen, A.O., Sillastu, H.: Potentiative effects of neutral proteinases in an inflamed lung: Relationship of neutrophil procollagenase (proMMP-8) to plasmin, cathepsin G and tryptase in bronchiectasis in vivo. EUROPEAN RESPIRATORY JOURNAL. 10, 2788-2793 (1997).

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• [135]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627649

  Sorsa, T., Salo, T., Koivunen, E., Tyynela, J., Konttinen, Y.T., Bergmann, U., Tuuttila, A., Niemi, E., Teronen, O., Heikkila, P., Tschesche, H., Leinonen, J., Osman, S., Stenman, U.H.: Activation of type IV procollagenases by human tumor-associated trypsin-2. JOURNAL OF BIOLOGICAL CHEMISTRY. 272, 21067-21074 (1997).

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  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627719

  Pieper, M., Betz, M., Budisa, N., GomisRuth, F.X., Bode, W., Tschesche, H.: Expression, purification, characterization, and x-ray analysis of selenomethionine 215 variant of leukocyte collagenase. JOURNAL OF PROTEIN CHEMISTRY. 16, 637-650 (1997).

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• [133]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627726

  Brinkmann, T., Schafers, J., Gurtler, L., Kido, H., Niwa, Y., Katunuma, N., Tschesche, H.: Inhibition of tryptase TL2 from human T4(+) lymphocytes and inhibition of HIV-1 replication in H9 cells by recombinant aprotinin and bikunin homologues. JOURNAL OF PROTEIN CHEMISTRY. 16, 651-660 (1997).

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• [132]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628123

  Kolben, M., Blaser, J., Ulm, K., Schmitt, M., Schneider, K.T.M., Tschesche, H., Graeff, H.: Angiogenin plasma levels during pregnancy. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 176, 37-41 (1997).

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• [131]
  

  1997 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1627416

  Tschesche, H.: Leukodiapedesis, function, and physiological role of leucocyte matrix metalloproteinases. CELLULAR PEPTIDASES IN IMMUNE FUNCTIONS AND DISEASES. 421, p. 285-301. PLENUM PRESS DIV PLENUM PUBLISHING CORP (1997).

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  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1637425

  Billinghurst, R.C., Dahlberg, L., Ionescu, M., Reiner, A., Bourne, R., Rorabeck, C., Mitchell, P., Hambor, J., Diekmann, O., Tschesche, H., Chen, J., VanWart, H., Poole, A.R.: Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage. JOURNAL OF CLINICAL INVESTIGATION. 99, 1534-1545 (1997).

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• [129]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626654

  Hanemaaijer, R., Sorsa, T., Konttinen, Y.T., Ding, Y.L., Sutinen, M., Visser, H., vanHinsbergh, V.W.M., Helaakoski, T., Kainulainen, T., Ronka, H., Tschesche, H., Salo, T.: Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells - Regulation by tumor necrosis factor-alpha and doxycycline. JOURNAL OF BIOLOGICAL CHEMISTRY. 272, 31504-31509 (1997).

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• [128]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627525

  Kroger, M., Tschesche, H.: Cloning, expression and activation of a truncated 92-kDa gelatinase minienzyme. GENE. 196, 175-180 (1997).

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• [127]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627908

  Betz, M., Huxley, P., Davies, S.J., Mushtaq, Y., Pieper, M., Tschesche, H., Bode, W., GomisRuth, F.X.: 1.8-angstrom crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate prime-side inhibitor with a distinct selectivity profile. EUROPEAN JOURNAL OF BIOCHEMISTRY. 247, 356-363 (1997).

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• [126]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1637465

  Knauper, V., Docherty, A.J.P., Smith, B., Tschesche, H., Murphy, G.: Analysis of the contribution of the hinge region of human neutrophil collagenase (HNC, MMP-8) to stability and collagenolytic activity by alanine scanning mutagenesis. FEBS LETTERS. 405, 60-64 (1997).

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• [125]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628000

  Brinkmann, T., Korfer, R., Wenzel, H., Tschesche, H., Kleesiek, K.: Strong crossreaction of human anti-aprotinin antibodies from heart transplant patient with [Arg(15)]aprotinin. IMMUNOPHARMACOLOGY. 35, 221-228 (1997).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [124]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628332

  Ingman, T., Tervahartiala, T., Ding, Y.L., Tschesche, H., Haerian, A., Kinane, D.F., Konttinen, Y.T., Sorsa, T.: Matrix metalloproteinases and their inhibitors in gingival crevicular fluid and saliva of periodontitis patients. JOURNAL OF CLINICAL PERIODONTOLOGY. 23, 1127-1132 (1996).

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• [123]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1639527

  Müthing, J., Spanbroek, R., PeterKatalinic, J., Hanisch, F.G., Hanski, C., Hasegawa, A., Unland, F., Lehmann, J., Tschesche, H., Egge, H.: Isolation and structural characterization of fucosylated gangliosides with linear poly-N-acetyllactosaminyl chains from human granulocytes. GLYCOBIOLOGY. 6, 147-156 (1996).

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• [122]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1639133

  Romisch, J., Krahl, U., Hock, J., Blaser, J., Fricke, R., Maasjosthusmann, U., Tschesche, H.: Quantification of hemostatic proteins and activation products in synovial fluids from arthritic joints prior to and after induction of chemical synoviorthesis. HAEMOSTASIS. 26, 170-177 (1996).

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• [121]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628600

  Ottl, J., Battistuta, R., Pieper, M., Tschesche, H., Bode, W., Kuhn, K., Moroder, L.: Design and synthesis of heterotrimeric collagen peptides with a built-in cystine-knot - Models for collagen catabolism by matrix-metalloproteases. FEBS LETTERS. 398, 31-36 (1996).

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• [120]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1639086

  Schonermark, M., Mester, B., Kempf, H.G., Blaser, J., Tschesche, H., Lenarz, T.: Expression of matrix-metalloproteinases and their inhibitors in human cholesteatomas. ACTA OTO-LARYNGOLOGICA. 116, 451-456 (1996).

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• [119]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629053

  Knauper, V., Murphy, G., Tschesche, H.: Activation of human neutrophil procollagenase by stromelysin 2. EUROPEAN JOURNAL OF BIOCHEMISTRY. 235, 187-191 (1996).

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• [118]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628872

  Blaser, J., Triebel, S., Maasjosthusmann, U., Romisch, J., KrahlMateblowski, U., Freudenberg, W., Fricke, R., Tschesche, H.: Determination of metalloproteinases, plasminogen-activators and their inhibitors in the synovial fluids of patients with rheumatoid arthritis during chemical synoviorthesis. CLINICA CHIMICA ACTA. 244, 17-33 (1996).

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• [117]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1638047

  Lichte, A., Kolkenbrock, H., Tschesche, H.: The recombinant catalytic domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) induces activation of progelatinase A and progelatinase A complexed with TIMP-2. FEBS LETTERS. 397, 277-282 (1996).

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• [116]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1638472

  Kolben, M., Lopens, A., Blaser, J., Ulm, K., Schmitt, M., Schneider, K.T.M., Tschesche, H.: Proteases and their inhibitors are indicative in gestational disease. EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY. 68, 59-65 (1996).

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• [115]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629181

  TAKAGI, M., KONTTINEN, Y.T., KEMPPINEN, P., SORSA, T., Tschesche, H., BLASER, J., SUDA, A., SANTAVIRTA, S.: TISSUE INHIBITOR OF METALLOPROTEINASE-1, COLLAGENOLYTIC AND GELATINOLYTIC ACTIVITY IN LOOSE HIP ENDOPROSTHESES. JOURNAL OF RHEUMATOLOGY. 22, 2285-2290 (1995).

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• [114]
  

  1995 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1639623

  Kolben, M., Lopens, A., Blaser, J., Huber, A., Frank, M., Wilhelm, O., Wilhelm, S., Schneider, K.T.M., Ulm, K., Tschesche, H., Schmitt, M., Graeff, H.: Concentration of different proteolytic and angiogenic factors in plasma and placenta extract of patients with HELLP syndrome, pre-/eclampsia, and highly pathological Doppler flow measurements. Gynäkologisch-geburtshilfliche Rundschau. GYNÄKOLOGISCH-GEBURTSHILFLICHE RUNDSCHAU. 35, p. 126-131. KARGER (1995).

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• [113]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1640365

  SORSA, T., DING, Y.L., INGMAN, T., SALO, T., WESTERLUND, U., HAAPASALO, M., Tschesche, H., KONTTINEN, Y.T.: CELLULAR SOURCE, ACTIVATION AND INHIBITION OF DENTAL PLAQUE COLLAGENASE. JOURNAL OF CLINICAL PERIODONTOLOGY. 22, 709-717 (1995).

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  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629264

  KURSCHAT, P., GRAEVE, L., ERREN, A., GATSIOS, P., ROSEJOHN, S., ROEB, E., Tschesche, H., KOJ, A., HEINRICH, P.C.: EXPRESSION OF A BIOLOGICALLY-ACTIVE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN BACULOVIRUS-INFECTED INSECT CELLS - PURIFICATION AND TISSUE DISTRIBUTION IN THE RAT. EUROPEAN JOURNAL OF BIOCHEMISTRY. 234, 485-491 (1995).

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  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1639811

  GRAMS, F., CRIMMIN, M., HINNES, L., HUXLEY, P., PIEPER, M., Tschesche, H., BODE, W.: STRUCTURE DETERMINATION AND ANALYSIS OF HUMAN NEUTROPHIL COLLAGENASE COMPLEXED WITH A HYDROXAMATE INHIBITOR. BIOCHEMISTRY. 34, 14012-14020 (1995).

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  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641329

  GRAMS, F., REINEMER, P., POWERS, J.C., KLEINE, T., PIEPER, M., Tschesche, H., HUBER, R., BODE, W.: X-RAY STRUCTURES OF HUMAN NEUTROPHIL COLLAGENASE COMPLEXED WITH PEPTIDE HYDROXAMATE AND PEPTIDE THIOL INHIBITORS - IMPLICATIONS FOR SUBSTRATE-BINDING AND RATIONAL DRUG DESIGN. EUROPEAN JOURNAL OF BIOCHEMISTRY. 228, 830-841 (1995).

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• [109]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641742

  BARTSCH, S., Tschesche, H.: CLONING AND EXPRESSION OF HUMAN NEUTROPHIL LIPOCALIN CDNA DERIVED FROM BONE-MARROW AND OVARIAN-CANCER CELLS. FEBS LETTERS. 357, 255-259 (1995).

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  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1640472

  TRIEBEL, S., BLASER, J., GOTE, T., PELZ, G., SCHUREN, E., SCHMITT, M., Tschesche, H.: EVIDENCE FOR THE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN HUMAN POLYMORPHONUCLEAR LEUKOCYTES. EUROPEAN JOURNAL OF BIOCHEMISTRY. 231, 714-719 (1995).

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• [107]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641160

  DUFFY, M.J., BLASER, J., DUGGAN, C., MCDERMOTT, E., OHIGGINS, N., FENNELLY, J.J., Tschesche, H.: ASSAY OF MATRIX METALLOPROTEASES TYPE-8 AND TYPE-9 BY ELISA IN HUMAN BREAST-CANCER. BRITISH JOURNAL OF CANCER. 71, 1025-1028 (1995).

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• [106]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1640549

  OSMERS, R.G.W., BLASER, J., KUHN, W., Tschesche, H.: INTERLEUKIN-8 SYNTHESIS AND THE ONSET OF LABOR. OBSTETRICS AND GYNECOLOGY. 86, 223-229 (1995).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [105]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1640796

  BLASER, J., TRIEBEL, S., Tschesche, H.: A SANDWICH ENZYME-IMMUNOASSAY FOR THE DETERMINATION OF NEUTROPHIL LIPOCALIN IN BODY-FLUIDS. CLINICA CHIMICA ACTA. 235, 137-145 (1995).

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  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641415

  WACHTFOGEL, Y.T., HACK, C.E., NUIJENS, J.H., KETTNER, C., REILLY, T.M., KNABB, R.M., BISCHOFF, R., Tschesche, H., Wenzel, H., KUCICH, U., EDMUNDS, L.H., COLMAN, R.W.: SELECTIVE KALLIKREIN INHIBITORS ALTER HUMAN NEUTROPHIL ELASTASE RELEASE DURING EXTRACORPOREAL-CIRCULATION. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 268, H1352-H1357 (1995).

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• [103]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1640451

  Tschesche, H.: HUMAN NEUTROPHIL COLLAGENASE. PROTEOLYTIC ENZYMES: ASPARTIC AND METALLO PEPTIDASES. 248, 431-449 (1995).

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  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1640124

  BALKE, N., HOLTKAMP, U., HORL, W.H., Tschesche, H.: INHIBITION OF DEGRANULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY COMPLEMENT-FACTOR-D. FEBS LETTERS. 371, 300-302 (1995).

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• [101]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1644370

  LAUHIO, A., KONTTINEN, Y.T., Tschesche, H., NORDSTROM, D., SALO, T., LAHDEVIRTA, J., GOLUB, L.M., SORSA, T.: REDUCTION OF MATRIX METALLOPROTEINASE 8-NEUTROPHIL COLLAGENASE LEVELS DURING LONG-TERM DOXYCYCLINE TREATMENT OF REACTIVE ARTHRITIS. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 38, 400-402 (1994).

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  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1644189

  BODE, W., REINEMER, P., HUBER, R., KLEINE, T., SCHNIERER, S., Tschesche, H.: THE X-RAY CRYSTAL-STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN NEUTROPHIL COLLAGENASE INHIBITED BY A SUBSTRATE-ANALOG REVEALS THE ESSENTIALS FOR CATALYSIS AND SPECIFICITY. EMBO JOURNAL. 13, 1263-1269 (1994).

  PUB | DOI | WoS | PubMed | Europe PMC
   
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  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629460

  GUNTHER, M., HAUBECK, H.D., VANDELEUR, E., BLASER, J., BENDER, S., GUTGEMANN, I., FISCHER, D.C., Tschesche, H., GREILING, H., HEINRICH, P.C., GRAEVE, L.: TRANSFORMING GROWTH-FACTOR-BETA-1 REGULATES TISSUE INHIBITOR OF METALLOPROTEINASES-1 EXPRESSION IN DIFFERENTIATED HUMAN ARTICULAR CHONDROCYTES. ARTHRITIS AND RHEUMATISM. 37, 395-405 (1994).

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  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1644336

  REINEMER, P., GRAMS, F., HUBER, R., KLEINE, T., SCHNIERER, S., PIPER, M., Tschesche, H., BODE, W.: STRUCTURAL IMPLICATIONS FOR THE ROLE OF THE N-TERMINUS IN THE SUPERACTIVATION OF COLLAGENASES - A CRYSTALLOGRAPHIC STUDY. FEBS LETTERS. 338, 227-233 (1994).

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  1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1640745

  LAUHIO, A., KONTTINEN, Y.T., SALO, T., Tschesche, H., LAHDEVIRTA, J., WOESSNER, F., GOLUB, L.M., SORSA, T.: PLACEBO-CONTROLLED STUDY OF THE EFFECTS OF 3-MONTH LYMECYCLINE TREATMENT ON SERUM MATRIX METALLOPROTEINASES IN REACTIVE ARTHRITIS. INHIBITION OF MATRIX METALLOPROTEINASES: THERAPEUTIC POTENTIAL. Annals of the New York Academy of Sciences. 732, p. 424-426. NEW YORK ACAD SCIENCES (1994).

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  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1643634

  HERTFELDER, H.J., SUWER, V., POPOVCENIC, S., Tschesche, H., HANFLAND, P.: LEUKOCYTE PROTEINASE RELEASE DURING STORAGE OF RED-CELL CONCENTRATES. EUROPEAN JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY. 32, 441-447 (1994).

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• [95]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1642061

  Tschesche, H., KOPP, C., HORL, W.H., HEMPELMANN, U.: INHIBITION OF DEGRANULATION OF POLYMORPHONUCLEAR LEUKOCYTES BY ANGIOGENIN AND ITS TRYPTIC FRAGMENT. JOURNAL OF BIOLOGICAL CHEMISTRY. 269, 30274-30280 (1994).

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• [94]
  

  1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1640736

  Tschesche, H., BLÄSER, J., KLEINE, T., SCHNIERER, S., REINEMER, P., BODE, W., MAASJOSHUSMANN, U., FRICKE, C.: Inhibition of Matrix Metalloproteinases in Rheumatoid Arthritis and the Crystallographic Binding Mode of a Peptide Inhibitor. Inhibition of Matrix Metalloproteinases: Therapeutic Potential. Annals of the New York Academy of Sciences. 732, p. 400-402. New York Acad. of Sciences (1994).

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  1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1642954

  DIEKMANN, O., Tschesche, H.: DEGRADATION OF KININS, ANGIOTENSINS AND SUBSTANCE-P BY POLYMORPHONUCLEAR MATRIX METALLOPROTEINASES MMP-8 AND MMP-9. Braz J Med Biol Res. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH. 27, p. 1865-1876. ASSOC BRAS DIVULG CIENTIFICA (1994).

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  1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1640732

  KNAUPER, V., MURPHY, G., Tschesche, H.: NEUTROPHIL PROCOLLAGENASE CAN BE ACTIVATED BY STROMELYSIN-2. INHIBITION OF MATRIX METALLOPROTEINASES: THERAPEUTIC POTENTIAL. Annals of the New York Academy of Sciences. 732, p. 367-368. NEW YORK ACAD SCIENCES (1994).

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  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1642545

  LAUHIO, A., SALO, T., DING, Y., KONTTINEN, Y.T., NORDSTROM, D., Tschesche, H., LAHDEVIRTA, J., GOLUB, L.M., SORSA, T.: IN-VIVO INHIBITION OF HUMAN NEUTROPHIL COLLAGENASE (MMP-8) ACTIVITY DURING LONG-TERM COMBINATION THERAPY OF DOXYCYCLINE AND NONSTEROIDAL ANTIINFLAMMATORY DRUGS (NSAID) IN ACUTE REACTIVE ARTHRITIS. CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 98, 21-28 (1994).

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  1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1642932

  Tschesche, H., KNAUPER, V., KLEINE, T., REINEMER, P., SCHNIERER, S., GRAMS, F., BODE, W.: FUNCTION AND STRUCTURE OF HUMAN-LEUKOCYTE COLLAGENASE. JOURNAL OF PROTEIN CHEMISTRY. 13, 460-461 (1994).

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• [89]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1642944

  GROEGER, C., Wenzel, H., Tschesche, H.: BPTI BACKBONE VARIANTS AND IMPLICATIONS FOR INHIBITORY ACTIVITY. INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH. 44, 166-172 (1994).

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• [88]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641996

  KONTTINEN, Y.T., KANGASPUNTA, P., LINDY, O., TAKAGI, M., SORSA, T., SEGERBERG, M., Tschesche, H., EISEN, A.Z.: COLLAGENASE IN SJOGRENS-SYNDROME. ANNALS OF THE RHEUMATIC DISEASES. 53, 836-839 (1994).

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  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1642014

  FOSANG, A.J., LAST, K., NEAME, P.J., MURPHY, G., KNAUPER, V., Tschesche, H., HUGHES, C.E., CATERSON, B., HARDINGHAM, T.E.: NEUTROPHIL COLLAGENASE (MMP-8) CLEAVES AT THE AGGRECANASE SITE E(373)-A(374) IN THE INTERGLOBULAR DOMAIN OF CARTILAGE AGGRECAN. BIOCHEMICAL JOURNAL. 304, 347-351 (1994).

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  1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1640754

  LAUHIO, A., KONTTINEN, Y.T., SALO, T., Tschesche, H., NORDSTROM, D., LAHDEVIRTA, J., GOLUB, L.M., SORSA, T.: THE IN-VIVO EFFECT OF DOXYCYCLINE TREATMENT ON MATRIX METALLOPROTEINASES IN REACTIVE ARTHRITIS. INHIBITION OF MATRIX METALLOPROTEINASES: THERAPEUTIC POTENTIAL. 732, p. 431-432. NEW YORK ACAD SCIENCES (1994).

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• [85]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629452

  OSMERS, R., Tschesche, H., RATH, W., SZEVERENYI, M., SUWER, V., WOLKER, I., KUHN, W.: SERUM COLLAGENASE LEVELS DURING PREGNANCY AND PARTURITION. EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY. 53, 55-57 (1994).

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  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1645769

  Müthing, J., UNLAND, F., HEITMANN, D., ORLICH, M., HANISCH, F.G., PETERKATALINIC, J., KNAUPER, V., Tschesche, H., KELM, S., SCHAUER, R., LEHMANN, J.: DIFFERENT BINDING-CAPACITIES OF INFLUENZA-A AND SENDAI VIRUSES TO GANGLIOSIDES FROM HUMAN GRANULOCYTES. GLYCOCONJUGATE JOURNAL. 10, 120-126 (1993).

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  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1646436

  SCHNIERER, S., KLEINE, T., GOTE, T., HILLEMANN, A., KNAUPER, V., Tschesche, H.: THE RECOMBINANT CATALYTIC DOMAIN OF HUMAN NEUTROPHIL COLLAGENASE LACKS TYPE-I COLLAGEN SUBSTRATE-SPECIFICITY. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 191, 319-326 (1993).

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  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1644764

  KLEINE, T., BARTSCH, S., BLASER, J., SCHNIERER, S., TRIEBEL, S., VALENTIN, M., GOTE, T., Tschesche, H.: PREPARATION OF ACTIVE RECOMBINANT TIMP-1 FROM ESCHERICHIA-COLI INCLUSION-BODIES AND COMPLEX-FORMATION WITH THE RECOMBINANT CATALYTIC DOMAIN OF PMNL-COLLAGENASE. BIOCHEMISTRY. 32, 14125-14131 (1993).

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  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1645008

  KNAUPER, V., WILHELM, S.M., SEPERACK, P.K., DECLERCK, Y.A., LANGLEY, K.E., OSTHUES, A., Tschesche, H.: DIRECT ACTIVATION OF HUMAN NEUTROPHIL PROCOLLAGENASE BY RECOMBINANT STROMELYSIN. BIOCHEMICAL JOURNAL. 295, 581-586 (1993).

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• [80]
  

  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1644986

  PELZ, G., SCHETTLER, A., Tschesche, H.: GRANULOCYTE CHEMOTAXIS MEASURED IN A BOYDEN CHAMBER ASSAY BY QUANTIFICATION OF NEUTROPHIL ELASTASE. EUROPEAN JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY. 31, 651-656 (1993).

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  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1645302

  BLASER, J., TRIEBEL, S., KOPP, C., Tschesche, H.: A HIGHLY SENSITIVE IMMUNOENZYMOMETRIC ASSAY FOR THE DETERMINATION OF ANGIOGENIN. EUROPEAN JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY. 31, 513-516 (1993).

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  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1645908

  KNAUPER, V., OSTHUES, A., DECLERCK, Y.A., LANGLEY, K.E., BLASER, J., Tschesche, H.: FRAGMENTATION OF HUMAN POLYMORPHONUCLEAR-LEUKOCYTE COLLAGENASE. BIOCHEMICAL JOURNAL. 291, 847-854 (1993).

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• [77]
  

  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1645121

  FOSANG, A.J., LAST, K., KNAUPER, V., NEAME, P.J., MURPHY, G., HARDINGHAM, T.E., Tschesche, H., HAMILTON, J.A.: FIBROBLAST AND NEUTROPHIL COLLAGENASES CLEAVE AT 2 SITES IN THE CARTILAGE AGGRECAN INTERGLOBULAR DOMAIN. BIOCHEMICAL JOURNAL. 295, 273-276 (1993).

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  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1645607

  GROEGER, C., Wenzel, H., Tschesche, H.: THE IMPORTANCE OF THE RIGIDITY OF THE PEPTIDE BACKBONE FOR THE INHIBITORY PROPERTIES OF BPTI DEMONSTRATED BY SEMISYNTHETIC STRUCTURAL VARIANTS. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH. 32, 898-900 (1993).

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• [75]
  

  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1668541

  Tschesche, H., Knauper, V., Kramer, S., Michaelis, J., Oberhoff, R., Reinke, H.: Latent collagenase and gelatinase from human neutrophils and their activation. Matrix Suppl. 1, 637-640 (1992).

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  1992 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1647795

  BAKOWSKI, B., Tschesche, H.: MIGRATION OF POLYMORPHONUCLEAR LEUKOCYTES THROUGH HUMAN AMNION MEMBRANE - A SCANNING ELECTRON-MICROSCOPIC STUDY. Eur J Protistol. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 373, p. 529-546. WALTER DE GRUYTER & CO (1992).

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  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1646963

  TRIEBEL, S., BLASER, J., REINKE, H., Tschesche, H.: A 25 KDA ALPHA-2-MICROGLOBULIN-RELATED PROTEIN IS A COMPONENT OF THE 125-KDA FORM OF HUMAN GELATINASE. FEBS LETTERS. 314, 386-388 (1992).

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  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1647172

  KORDULA, T., GUTTGEMANN, I., ROSEJOHN, S., ROEB, E., OSTHUES, A., Tschesche, H., KOJ, A., HEINRICH, P.C., GRAEVE, L.: SYNTHESIS OF TISSUE INHIBITOR OF METALLOPROTEINASE-1 (TIMP-1) IN HUMAN HEPATOMA-CELLS (HEPG2) - UP-REGULATION BY INTERLEUKIN-6 AND TRANSFORMING GROWTH FACTOR-BETA-1. FEBS LETTERS. 313, 143-147 (1992).

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  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1647223

  BLASER, J., TRIEBEL, S., REINKE, H., Tschesche, H.: FORMATION OF A COVALENT HG-CYS-BOND DURING MERCURIAL ACTIVATION OF PMNL PROCOLLAGENASE GIVES EVIDENCE OF A CYSTEINE-SWITCH MECHANISM. FEBS LETTERS. 313, 59-61 (1992).

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  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1648227

  OSMERS, R., RATH, W., ADELMANNGRILL, B.C., FITTKOW, C., KULOCZIK, M., SZEVERENYI, M., Tschesche, H., KUHN, W.: ORIGIN OF CERVICAL COLLAGENASE DURING PARTURITION. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 166, 1455-1460 (1992).

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  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1648633

  TRIEBEL, S., BLASER, J., REINKE, H., KNAUPER, V., Tschesche, H.: MERCURIAL ACTIVATION OF HUMAN-PMN LEUKOCYTE TYPE-IV PROCOLLAGENASE (GELATINASE). FEBS LETTERS. 298, 280-284 (1992).

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  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629750

  OSTHUES, A., KNAUPER, V., OBERHOFF, R., REINKE, H., Tschesche, H.: ISOLATION AND CHARACTERIZATION OF TISSUE INHIBITORS OF METALLOPROTEINASES (TIMP-1 AND TIMP-2) FROM HUMAN RHEUMATOID SYNOVIAL-FLUID. FEBS LETTERS. 296, 16-20 (1992).

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• [67]
  

  1991 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1629600

  Tschesche, H., Groeger, C., Wenzel, H.: ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN. Emerg Med J. BIOMEDICA BIOCHIMICA ACTA. 50, p. S175-S180. AKADEMIE VERLAG GMBH (1991).

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• [66]
  

  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948292

  Tschesche, H., Bakowski, B., Schettler, A., Knauper, V., Reinke, H., Kramer, S.: Leukodiapedesis, compartmentalisation and secretion of PMN leukocyte proteinases, and activation of PMN leukocyte procollagenase. Adv Exp Med Biol. 297, 503-517 (1991).

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  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1649242

  GROEGER, C., Wenzel, H., Tschesche, H.: CHEMICAL SEMISYNTHESIS OF APROTININ HOMOLOGS AND DERIVATIVES MUTATED IN P' POSITIONS. JOURNAL OF PROTEIN CHEMISTRY. 10, 527-533 (1991).

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• [64]
  

  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1648787

  BLASER, J., KNAUPER, V., OSTHUES, A., REINKE, H., Tschesche, H.: MERCURIAL ACTIVATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE PROCOLLAGENASE. EUROPEAN JOURNAL OF BIOCHEMISTRY. 202, 1223-1230 (1991).

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• [63]
  

  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1649315

  KNAUPER, V., TRIEBEL, S., REINKE, H., Tschesche, H.: INACTIVATION OF HUMAN PLASMA CL-INHIBITOR BY HUMAN-PMN LEUKOCYTE MATRIX METALLOPROTEINASES. FEBS LETTERS. 290, 99-102 (1991).

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  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1649962

  GROEGER, C., Wenzel, H., Tschesche, H.: ENZYMATIC SEMISYNTHESIS OF APROTININ HOMOLOGS MUTATED IN P' POSITIONS. JOURNAL OF PROTEIN CHEMISTRY. 10, 245-251 (1991).

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  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1650109

  SCHETTLER, A., THORN, H., JOCKUSCH, B.M., Tschesche, H.: RELEASE OF PROTEINASES FROM STIMULATED POLYMORPHONUCLEAR LEUKOCYTES - EVIDENCE FOR SUBCLASSES OF THE MAIN GRANULE TYPES AND THEIR ASSOCIATION WITH CYTOSKELETAL COMPONENTS. EUROPEAN JOURNAL OF BIOCHEMISTRY. 197, 197-202 (1991).

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  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1649119

  BRINKMANN, T., SCHNIERER, S., Tschesche, H.: RECOMBINANT APROTININ HOMOLOG WITH NEW INHIBITORY SPECIFICITY FOR CATHEPSIN-G. EUROPEAN JOURNAL OF BIOCHEMISTRY. 202, 95-99 (1991).

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  1991 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1649190

  Tschesche, H., BAKOWSKI, B., SCHETTLER, A., KNAUPER, V., REINKE, H.: LEUKODIAPEDESIS, RELEASE OF PMN LEUKOCYTE PROTEINASES AND ACTIVATION OF PMNL PROCOLLAGENASE. Transplantation. BIOMEDICA BIOCHIMICA ACTA. 50, p. 755-761. AKADEMIE VERLAG GMBH (1991).

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  1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1650075

  HEMPELMANN, U., HAAGWEBER, M., HORL, W.H., Tschesche, H.: EFFECT OF IMMUNOSUPPRESSIVE DRUGS ON THE RELEASE OF METALLOPROTEINASES FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES. TRANSPLANT INTERNATIONAL. 4, 26-30 (1991).

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  1990 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1650618

  SOPATA, I., MICHAELIS, J., Tschesche, H.: THE ACTIVATION OF HUMAN NEUTROPHIL GELATINASE. Acta Biochim Pol. ACTA BIOCHIMICA POLONICA. 37, p. 181-185. ACTA BIOCHIMICA POLONICA (1990).

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  1990 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1651267

  KNAUPER, V., KRAMER, S., REINKE, H., Tschesche, H.: PARTIAL AMINO-ACID-SEQUENCE OF HUMAN-PMN LEUKOCYTE PROCOLLAGENASE. Biol Chem Hoppe Seyler. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 371, p. 295-304. WALTER DE GRUYTER & CO (1990).

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  1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1651577

  KNAUPER, V., KRAMER, S., REINKE, H., Tschesche, H.: CHARACTERIZATION AND ACTIVATION OF PROCOLLAGENASE FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES - N-TERMINAL SEQUENCE DETERMINATION OF THE PROENZYME AND VARIOUS PROTEOLYTICALLY ACTIVATED FORMS. EUROPEAN JOURNAL OF BIOCHEMISTRY. 189, 295-300 (1990).

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• [54]
  

  1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1650922

  Wenzel, H., FELDMANN, A., ENGELBRECHT, S., Tschesche, H.: ACTIVATION OF THE HUMAN-LEUKOCYTE PROTEINASES ELASTASE AND CATHEPSIN-G BY VARIOUS SURFACTANTS. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 371, 721-724 (1990).

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• [53]
  

  1990 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1651264

  BRINKMANN, T., Tschesche, H.: DESIGN OF AN APROTININ VARIANT WITH INHIBITORY ACTIVITY AGAINST CHYMOTRYPSIN AND CATHEPSIN-G BY RECOMBINANT-DNA TECHNOLOGY. Farm Hosp. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 371, p. 43-52. WALTER DE GRUYTER & CO (1990).

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  1990 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1650622

  WIZE, J., KNAUPER, V., Tschesche, H.: SOME PROPERTIES OF LATENT COLLAGENASE FROM HUMAN SYNOVIAL-FLUID. Acta Biochim Pol. ACTA BIOCHIMICA POLONICA. 37, p. 201-206. ACTA BIOCHIMICA POLONICA (1990).

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  1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1650797

  RATH, W., OSMERS, R., ADELMANNGRILL, B.C., STUHLSATZ, H.W., Tschesche, H., SZEVERINI, M.: FUNDAMENTALS OF PHYSIOLOGICAL AND DRUG-INDUCED CERVICAL RIPENING - NEW MORPHOLOGICAL AND BIOCHEMICAL FINDINGS. GEBURTSHILFE UND FRAUENHEILKUNDE. 50, 657-664 (1990).

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  1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1651100

  NITSCH, M., GABRIJELCIC, D., Tschesche, H.: SEPARATION OF GRANULE SUBPOPULATIONS IN HUMAN POLYMORPHONUCLEAR LEUKOCYTES. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 371, 611-616 (1990).

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  1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1651592

  KNAUPER, V., REINKE, H., Tschesche, H.: INACTIVATION OF HUMAN PLASMA ALPHA-1-PROTEINASE INHIBITOR BY HUMAN-PMN LEUKOCYTE COLLAGENASE. FEBS LETTERS. 263, 355-357 (1990).

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  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1652842

  MEHLICH, A., BECKMANN, J., Wenzel, H., Tschesche, H.: SEMISYNTHETIC APROTININ DERIVATIVES WITH SPECIFIC ALTERATIONS AT THE REACTIVE-SITE PEPTIDE-BOND CAN BE USED TO STUDY STRUCTURE-FUNCTION-RELATIONSHIPS. BIOCHIMICA ET BIOPHYSICA ACTA. 996, 23-29 (1989).

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  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1652755

  BERGMANN, U., MICHAELIS, J., OBERHOFF, R., KNAUPER, V., BECKMANN, R., Tschesche, H.: ENZYME LINKED IMMUNOSORBENT ASSAYS (ELISA) FOR THE QUANTITATIVE-DETERMINATION OF HUMAN-LEUKOCYTE COLLAGENASE AND GELATINASE. JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY. 27, 351-359 (1989).

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  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1652670

  SIEKMANN, J., BECKMANN, J., MEHLICH, A., Wenzel, H., Tschesche, H., SCHNABEL, E., MULLERESTERL, W.: IMMUNOLOGICAL CHARACTERIZATION OF NATURAL AND SEMISYNTHETIC APROTININ VARIANTS. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 370, 677-682 (1989).

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  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948401

  Tschesche, H., Beckmann, J., Mehlich, A., Feldmann, A., Wenzel, H.R., Scott, C.F., Colman, R.W.: Semisynthetic arginine-15-aprotinin, an improved inhibitor for human plasma kallikrein. Adv Exp Med Biol. 247B, 15-21 (1989).

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  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948420

  Tschesche, H., Michaelis, J., Kohnert, U., Fedrowitz, J., Oberhoff, R.: Tissue kallikrein effectively activates latent matrix degrading metalloenzymes. Adv Exp Med Biol. 247A, 280-284 (1989).

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  1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653324

  BECKMANN, J., MEHLICH, A., SCHRODER, W., Wenzel, H., Tschesche, H.: SEMISYNTHESIS OF ARG-15-APROTININ, GLU-15-APROTININ, MET-15-APROTININ, AND NLE15-APROTININ INVOLVING ENZYMATIC PEPTIDE-BOND RESYNTHESIS. JOURNAL OF PROTEIN CHEMISTRY. 8, 101-113 (1989).

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  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653441

  MEHLICH, A., BECKMANN, J., Wenzel, H., Tschesche, H.: APROTININ DERIVATIVES WITH CHROMOPHORIC LEAVING GROUPS CAN BE USED AS HIGHLY SELECTIVE ACTIVE-SITE TITRANTS FOR SERINE PROTEINASES AND PERMIT THE DETERMINATION OF KINETIC CONSTANTS OF ENZYME-INHIBITOR COMPLEXES. BIOCHIMICA ET BIOPHYSICA ACTA. 957, 420-429 (1988).

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  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653768

  BECKMANN, J., MEHLICH, A., SCHRODER, W., Wenzel, H., Tschesche, H.: PREPARATION OF CHEMICALLY MUTATED APROTININ HOMOLOGS BY SEMISYNTHESIS - P1 SUBSTITUTIONS CHANGE INHIBITORY SPECIFICITY. EUROPEAN JOURNAL OF BIOCHEMISTRY. 176, 675-682 (1988).

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  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654061

  SCHNABEL, E., REINHARDT, G., SCHRODER, W., Tschesche, H., Wenzel, H., MEHLICH, A.: ENZYMATIC RESYNTHESIS OF THE REACTIVE SITE BOND IN THE MODIFIED APROTININ DERIVATIVES [SECO-15/16]APROTININ AND [DI-SECO-15/16,39/40]APROTININ. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 369, 461-468 (1988).

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  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654439

  SIEKMANN, J., Wenzel, H., SCHRODER, W., Tschesche, H.: CHARACTERIZATION AND SEQUENCE DETERMINATION OF 6 APROTININ HOMOLOGS FROM BOVINE LUNGS. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 369, 157-164 (1988).

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  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1653623

  SIEKMANN, J., Wenzel, H., MATUSZAK, E., VONGOLDAMMER, E., Tschesche, H.: THE PH-DEPENDENCE OF THE EQUILIBRIUM-CONSTANT KHYD FOR THE HYDROLYSIS OF THE LYS15-ALA16 REACTIVE-SITE PEPTIDE-BOND IN BOVINE PANCREATIC TRYPSIN-INHIBITOR (APROTININ). JOURNAL OF PROTEIN CHEMISTRY. 7, 633-640 (1988).

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  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948537

  von Clausbruch, U.C., Tschesche, H.: Cathepsin D from human leukocytes. Purification by affinity chromatography and properties of the enzyme. Biol Chem Hoppe Seyler. 369, 683-691 (1988).

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  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948517

  Kohnert, U., Oberhoff, R., Fedrowitz, J., Bergmann, U., Rauterberg, J., Tschesche, H.: The degradation of collagen by a metalloproteinase from human leucocytes. Adv Exp Med Biol. 240, (1988).

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  1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948524

  Beckmann, J., Mehlich, A., Wenzel, H., Tschesche, H.: Semisynthetic inhibitors of human leukocyte elastase and their protective effect on lung elastin degradation in vitro. Adv Exp Med Biol. 240, 107-114 (1988).

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  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1655827

  KOLKENBROCK, H., Tschesche, H.: A NEW INHIBITOR OF ELASTASE FROM THE SEA-ANEMONE (ANEMONIA-SULCATA). BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 368, 93-100 (1987).

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• [33]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654892

  Tschesche, H., KOLKENBROCK, H., BODE, W.: THE COVALENT STRUCTURE OF THE ELASTASE INHIBITOR FROM ANEMONIA-SULCATA - A NONCLASSICAL KAZAL-TYPE PROTEIN. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 368, 1297-1304 (1987).

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• [32]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1655390

  Tschesche, H., BECKMANN, J., MEHLICH, A., SCHNABEL, E., TRUSCHEIT, E., Wenzel, H.: SEMISYNTHETIC ENGINEERING OF PROTEINASE-INHIBITOR HOMOLOGS. BIOCHIMICA ET BIOPHYSICA ACTA. 913, 97-101 (1987).

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• [31]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1655547

  SCOTT, C.F., Wenzel, H., Tschesche, H., COLMAN, R.W.: KINETICS OF INHIBITION OF HUMAN-PLASMA KALLIKREIN BY A SITE-SPECIFIC MODIFIED INHIBITOR ARG15-APROTININ - EVALUATION USING A MICROPLATE SYSTEM AND COMPARISON WITH OTHER PROTEASES. BLOOD. 69, 1431-1436 (1987).

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• [30]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654700

  SIEKMANN, J., Wenzel, H., SCHRODER, W., SCHUTT, H., TRUSCHEIT, E., ARENS, A., RAUENBUSCH, E., CHAZIN, W.J., WUTHRICH, K., Tschesche, H.: PYROGLUTAMYL-APROTININ, A NEW APROTININ HOMOLOG FROM BOVINE LUNGS - ISOLATION, PROPERTIES, SEQUENCE-ANALYSIS AND CHARACTERIZATION USING HYDROGEN NUCLEAR MAGNETIC-RESONANCE IN SOLUTION. BIOLOGICAL CHEMISTRY HOPPE-SEYLER. 368, 1589-1596 (1987).

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• [29]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1654832

  HANKOVSZKY, O.H., HIDEG, K., VONGOLDAMMER, E., MATUSZAK, E., KOLKENBROCK, H., Tschesche, H., Wenzel, H.: NEW NITROXIDE REAGENTS FOR THE SELECTIVE SPIN-LABELING AT THE GUANIDINO MOIETY OF ARGININE RESIDUES IN PEPTIDES AND PROTEINS. BIOCHIMICA ET BIOPHYSICA ACTA. 916, 152-155 (1987).

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• [28]
  

  1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1655347

  SCHWARZ, H., HINZ, H.J., MEHLICH, A., Tschesche, H., Wenzel, H.: STABILITY STUDIES ON DERIVATIVES OF THE BOVINE PANCREATIC TRYPSIN-INHIBITOR. BIOCHEMISTRY. 26, 3544-3551 (1987).

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• [27]
  

  1986 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1656879

  BURKHARDT, H., SCHWINGEL, M., MENNINGER, H., MACARTNEY, H.W., Tschesche, H.: OXYGEN RADICALS AS EFFECTORS OF CARTILAGE DESTRUCTION - DIRECT DEGRADATIVE EFFECT ON MATRIX COMPONENTS AND INDIRECT ACTION VIA ACTIVATION OF LATENT COLLAGENASE FROM POLYMORPHONUCLEAR LEUKOCYTES. ARTHRITIS AND RHEUMATISM. 29, 379-387 (1986).

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• [26]
  

  1986 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1656221

  Tschesche, H., FEDROWITZ, J., KOHNERT, U., MICHAELIS, J., MACARTNEY, H.W.: MATRIX DEGRADING PROTEINASES FROM HUMAN-GRANULOCYTES - TYPE-I, TYPE-II, TYPE-III COLLAGENASE, GELATINASE AND TYPE-IV, TYPE-V-COLLAGENASE - A SURVEY OF RECENT FINDINGS AND INHIBITION BY GAMMA-ANTICOLLAGENASE. FOLIA HISTOCHEMICA ET CYTOBIOLOGICA. 24, 125-131 (1986).

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• [25]
  

  1985 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1657948

  FLORKEGERLOFF, S., KRAUSE, W., TOPFERPETERSEN, E., Tschesche, H., MULLERESTERL, W., ENGEL, W.: ON THE TERATOGENESIS OF ROUND-HEADED SPERMATOZOA - INVESTIGATIONS WITH ANTIBODIES AGAINST ACROSIN, AN INTRAACROSOMALLY LOCATED ACROSIN-INHIBITOR, AND THE OUTER ACROSOMAL MEMBRANE. ANDROLOGIA. 17, 126-138 (1985).

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• [24]
  

  1984 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1659171

  Tschesche, H.: STRUCTURE AND FUNCTION OF NATURAL INHIBITORS AS ANTAGONISTS OF PROTEINASE ACTIVITIES. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 167, 73-87 (1984).

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• [23]
  

  1984 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1658459

  FLORKEGERLOFF, S., Tschesche, H., MULLERESTERL, W., ENGEL, W.: INTRA-ACROSOMALLY LOCATED ACROSIN-INHIBITORS - EVOLUTION AND DEVELOPMENTAL PATTERNS IN MAMMALS. GAMETE RESEARCH. 10, 327-337 (1984).

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• [22]
  

  1984 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1658517

  BODE, W., WALTER, J., HUBER, R., Wenzel, H., Tschesche, H.: THE REFINED 2.2-A (0.22-NM) X-RAY CRYSTAL-STRUCTURE OF THE TERNARY COMPLEX FORMED BY BOVINE TRYPSINOGEN, VALINE-VALINE AND THE ARG15 ANALOG OF BOVINE PANCREATIC TRYPSIN-INHIBITOR. EUROPEAN JOURNAL OF BIOCHEMISTRY. 144, 185-190 (1984).

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• [21]
  

  1984 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1659279

  RAUTENBERG, W., Tschesche, H.: AMINOPEPTIDASES FROM HUMAN-LEUKOCYTES. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 365, 49-58 (1984).

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• [20]
  

  1984 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1659021

  SCHAUER, R., WEMBER, M., Tschesche, H.: ISOLATION AND CHARACTERIZATION OF AN OLIGOSACCHARIDE-SPECIFIC AND GLYCOPROTEIN-SPECIFIC SIALIDASE FROM HUMAN-LEUKOCYTES. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 365, 419-426 (1984).

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• [19]
  

  1983 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660235

  MACARTNEY, H.W., Tschesche, H.: INTERACTION OF BETA-1-ANTICOLLAGENASE FROM HUMAN-PLASMA WITH COLLAGENASES FROM VARIOUS TISSUES AND COMPETITION WITH ALPHA-2-MACROGLOBULIN. EUROPEAN JOURNAL OF BIOCHEMISTRY. 130, 93-97 (1983).

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• [18]
  

  1983 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660229

  MACARTNEY, H.W., Tschesche, H.: THE COLLAGENASE INHIBITOR FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES - ISOLATION, PURIFICATION AND CHARACTERIZATION. EUROPEAN JOURNAL OF BIOCHEMISTRY. 130, 79-83 (1983).

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• [17]
  

  1983 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660226

  MACARTNEY, H.W., Tschesche, H.: LATENT AND ACTIVE HUMAN POLYMORPHONUCLEAR LEUKOCYTE COLLAGENASES - ISOLATION, PURIFICATION AND CHARACTERIZATION. EUROPEAN JOURNAL OF BIOCHEMISTRY. 130, 71-78 (1983).

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• [16]
  

  1983 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660232

  MACARTNEY, H.W., Tschesche, H.: CHARACTERIZATION OF BETA-1-ANTICOLLAGENASE FROM HUMAN-PLASMA AND ITS REACTION WITH POLYMORPHONUCLEAR LEUKOCYTE COLLAGENASE BY DISULFIDE THIOL INTERCHANGE. EUROPEAN JOURNAL OF BIOCHEMISTRY. 130, 85-92 (1983).

  PUB | WoS | PubMed | Europe PMC
   
• [15]
  

  1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1630071

  Tschesche, H., WITTIG, B., DECKER, G., MULLERESTERL, W., FRITZ, H.: A NEW ACROSIN INHIBITOR FROM BOAR SPERMATOZOA. EUROPEAN JOURNAL OF BIOCHEMISTRY. 126, 99-104 (1982).

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• [14]
  

  1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660972

  ENGELBRECHT, S., PIEPER, E., MACARTNEY, H.W., RAUTENBERG, W., Wenzel, H., Tschesche, H.: SEPARATION OF THE HUMAN-LEUKOCYTE ENZYMES ALANINE AMINOPEPTIDASE, CATHEPSIN-G, COLLAGENASE, ELASTASE AND MYELOPEROXIDASE. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 363, 305-316 (1982).

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• [13]
  

  1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660931

  Wenzel, H., Tschesche, H., VONGOLDAMMER, E., NETZELMANN, U.: COMPLEX-FORMATION OF GUANIDINATED BOVINE TRYPSIN-INHIBITOR (KUNITZ) WITH TRYPSIN, CHYMOTRYPSIN AND TRYPSINOGEN AS STUDIED BY THE SPIN-LABEL TECHNIQUE. FEBS LETTERS. 140, 53-57 (1982).

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• [12]
  

  1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660955

  BURKHARDT, H., MENNINGER, H., BERNER, W., Wenzel, H., Tschesche, H., HOOS, R., MIERAU, H.D.: INHIBITION OF RHEUMATOID CARTILAGE DEGRADATION - A BIOMECHANICAL ASSAY FOR POTENTIAL ANTI-RHEUMATIC DRUGS. AKTUELLE RHEUMATOLOGIE. 7, 60-62 (1982).

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• [11]
  

  1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1661581

  SCHONBERGER, O.L., Tschesche, H.: N-ACETYLALANINE AMINOPEPTIDASE, A NEW ENZYME FROM HUMAN-ERYTHROCYTES. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 362, 865-874 (1981).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [10]
  

  1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1661286

  MACARTNEY, H.W., Tschesche, H.: THE METAL-ION REQUIREMENT FOR ACTIVATION OF LATENT COLLAGENASE FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 362, 1523-1532 (1981).

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• [9]
  

  1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1661306

  Tschesche, H., MACARTNEY, H.W.: A NEW PRINCIPLE OF REGULATION OF ENZYMIC ACTIVITY - ACTIVATION AND REGULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE COLLAGENASE VIA DISULFIDE-THIOL EXCHANGE AS CATALYZED BY THE GLUTATHIONE CYCLE IN A PEROXIDASE-COUPLED REACTION TO GLUCOSE-METABOLISM. EUROPEAN JOURNAL OF BIOCHEMISTRY. 120, 183-190 (1981).

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• [8]
  

  1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1661716

  Wenzel, H., Tschesche, H.: CHEMICAL MUTATION BY AMINO-ACID EXCHANGE IN THE REACTIVE SITE OF A PROTEINASE-INHIBITOR AND ALTERATION OF ITS INHIBITOR SPECIFITY. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH. 20, 295-296 (1981).

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• [7]
  

  1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1661674

  Wenzel, H., Tschesche, H.: CLEAVAGE OF PEPTIDE-4-NITROANILIDE SUBSTRATES WITH VARYING CHAIN-LENGTH BY HUMAN-LEUKOCYTE ELASTASE. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 362, 829-831 (1981).

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• [6]
  

  1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1660979

  FIEDLER, F., FINK, E., Tschesche, H., FRITZ, H.: PORCINE GLANDULAR KALLIKREINS. METHODS IN ENZYMOLOGY. 80, 493-532 (1981).

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• [5]
  

  1980 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1662058

  RICHARZ, R., Tschesche, H., WUTHRICH, K.: C-13 NUCLEAR MAGNETIC-RESONANCE STUDIES OF THE SELECTIVELY ISOTOPE-LABELED REACTIVE SITE PEPTIDE-BOND OF THE BASIC PANCREATIC TRYPSIN-INHIBITOR IN THE COMPLEXES WITH TRYPSIN, TRYPSINOGEN, AND ANHYDROTRYPSIN. BIOCHEMISTRY. 19, 5711-5715 (1980).

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• [4]
  

  1980 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1662124

  REISINGER, P., SEIDEL, H., Tschesche, H., HAMMES, W.P.: THE EFFECT OF NISIN ON MUREIN SYNTHESIS. ARCHIVES OF MICROBIOLOGY. 127, 187-193 (1980).

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• [3]
  

  1980 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1662186

  Wenzel, H., ENGELBRECHT, S., REICH, H., MONDRY, W., Tschesche, H.: SYNTHESIS AND ANALYTICAL USE OF 3-CARBOXYPROPIONYL-ALANYL-ALANYL-VALINE-4-NITROANILIDE - A SPECIFIC SUBSTRATE FOR HUMAN-LEUKOCYTE ELASTASE. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 361, 1413-1416 (1980).

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• [2]
  

  1980 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1662110

  MACARTNEY, H.W., Tschesche, H.: LATENT COLLAGENASE FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES AND ACTIVATION TO COLLAGENASE BY REMOVAL OF AN INHIBITOR. FEBS LETTERS. 119, 327-332 (1980).

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• [1]
  

  1978 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1663562

  SCHOBERT, B., Tschesche, H.: UNUSUAL SOLUTION PROPERTIES OF PROLINE AND ITS INTERACTION WITH PROTEINS. BIOCHIMICA ET BIOPHYSICA ACTA. 541, 270-277 (1978).

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