48 Publikationen
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2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2981846M. Sun, et al., “A novel homozygous missense variant in ARSK causes MPS X, a new subtype of mucopolysaccharidosis”, Genes & Diseases, 2023.PUB | DOI | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2962857A. Linhorst and T. Lübke, “The Human Ntn-Hydrolase Superfamily: Structure, Functions and Perspectives”, Cells, vol. 11, 2022, : 1592.PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2965167B.S. Haslund-Gourley, et al., “Establishment of blood glycosidase activities and their excursions in sepsis”, PNAS Nexus, vol. 1, 2022, : pgac113.PUB | DOI | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2956816B. Kowalewski, et al., “Decoding the consecutive lysosomal degradation of 3-O-sulfate containing heparan sulfate by Arylsulfatase G (ARSG)”, Biochemical Journal, 2021.PUB | DOI | WoS | PubMed | Europe PMC
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2948390T. Lübke and M. Damme, “Lysosomal sulfatases: a growing family*”, Biochemical Journal, vol. 477, 2020, pp. 3963-3983.PUB | DOI | WoS | PubMed | Europe PMC
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2945876C. Trabszo, et al., “Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfate”, Biochemical Journal, 2020.PUB | DOI | WoS | PubMed | Europe PMC
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2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2937243M. Korf-Klingebiel, et al., “Heparan Sulfate-Editing Extracellular Sulfatases Enhance Vascular Endothelial Growth Factor Bioavailability for Ischemic Heart Repair”, Circulation research, vol. 125, 2019, pp. 787-801.PUB | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920271S. Stroobants, et al., “Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis Mice”, FRONTIERS IN BEHAVIORAL NEUROSCIENCE, vol. 12, 2018, : 15.PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909150X. Pan, et al., “Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings”, PLoS One, vol. 12, 2017, : e0172854.PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2908778O.P. Dhamale, et al., “Arylsulfatase K is the Lysosomal 2-Sulfoglucuronate Sulfatase”, ACS Chemical Biology, vol. 12, 2017, pp. 367-373.PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2905616H. Wolf, et al., “A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease”, Disease Models & Mechanisms, vol. 9, 2016, pp. 1015-1028.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2658538X.Y. Kong, et al., “Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells”, Disease Models & Mechanisms, vol. 7, 2014, pp. 351-362.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2672894X. Pan, et al., “Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1”, PLoS genetics, vol. 10, 2014, : e1004146.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2699273B. Kowalewski, et al., “Molecular Characterization of Arylsulfatase G: EXPRESSION, PROCESSING, GLYCOSYLATION, TRANSPORT, AND ACTIVITY”, The Journal of biological chemistry, vol. 289, 2014, pp. 27992-28005.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2623550E. Wiegmann, et al., “Arylsulfatase K, a Novel Lysosomal Sulfatase”, Journal of Biological Chemistry, vol. 288, 2013, pp. 30019-30028.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2623533F. Milz, et al., “Cooperation of binding sites at the hydrophilic domain of cell-surface sulfatase Sulf1 allows for dynamic interaction of the enzyme with its substrate heparan sulfate”, Biochim Biophys Acta, vol. 1830, 2013, pp. 5287-5298.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471754G. Makrypidi, et al., “Mannose 6 dephosphorylation of lysosomal proteins mediated by Acid phosphatases acp2 and acp5”, Molecular and cellular biology, vol. 32, 2012, pp. 774-782.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2529586K. Kollmann, et al., “Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' mice”, Brain, vol. 135, 2012, pp. 2661-2675.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2494022B. Kowalewski, et al., “Arylsulfatase G Inactivation Causes Loss of Heparan Sulfate 3-O-Sulfatase Activity and Mucopolysaccharidosis in Mice”, Proc. Natl. Acad. Sci. USA, vol. 109, 2012, pp. 10310-10315.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940515M. Damme, et al., “Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in alpha-mannosidosis”, Journal of Neuropathology & Experimental Neurology, vol. 70, 2011, pp. 83-94.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2352585L.R. Savalas, et al., “Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L.”, Biochemical Journal, vol. 436, 2011, pp. 113-121.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939855C. Rosner, et al., “Erratum to: Rhesus macaque MHC class I molecules show differential subcellular localizations”, Immunogenetics, vol. 62, 2010, pp. 409-418.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2776186C. Rosner, et al., “Rhesus macaque MHC class I molecules show differential subcellular localizations”, Immunogenetics, vol. 62, 2010, pp. 149-158.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939885K. Kollmann, et al., “Mannose phosphorylation in health and disease”, European Journal of Cell Biology, vol. 89, 2010, pp. 117-123.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902203M. Damme, et al., “Impaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis.”, Molecular and Cellular Biology, vol. 30, 2010, pp. 273-283.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939923K. Lakomek, et al., “Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography”, BMC Structural Biology, vol. 9, 2009, pp. 56-72.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902143O. Schieweck, et al., “NCU-G1 is a highly glycosylated integral membrane protein of the lysosome.”, Biochemical Journal, vol. 422, 2009, pp. 83-90.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939981T. Lübke, P. Lobel, and D.E. Sleat, “Proteomics of the lysosome”, Biochimica et Biophysica Acta, vol. 1793, 2009, pp. 625-635.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940533K. Kollmann, et al., “Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1”, Febs Journal, vol. 276, 2009, pp. 1356-1369.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939939K. Lakomek, et al., “De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse”, Acta Crystallographica Section D, vol. 65, 2009, pp. 220-228.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | PUB-ID: 1940006C. Hellbusch, et al., “Golgi GDP-fucose transporter-deficient mice mimic congenital disorder of glycosylation IIc/leukocyte adhesion deficiency II”, Journal of Biological Chemistry, vol. 282, 2007, pp. 10762-10772.PUB | DOI | WoS | PubMed | Europe PMC
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940030F. Deuschl, et al., “Molecular characterization of the hypothetical 66.3-kDa protein in mouse: lysosomal targeting, glycosylation, processing and tissue distribution”, Febs Letters, vol. 580, 2006, pp. 5747-5752.PUB | DOI | WoS | PubMed | Europe PMC
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940045C. Thiel, et al., “Targeted disruption of the mouse phosphomannomutase 2 gene causes early embryonic lethality”, Molecular and Cellular Biology, vol. 26, 2006, pp. 5615-5620.PUB | DOI | WoS | PubMed | Europe PMC
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940057S. Tiede, et al., “Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferase”, Nature Medicine, vol. 11, 2006, pp. 1109-1112.PUB | DOI | WoS | PubMed | Europe PMC
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940072K. Kollmann, et al., “Identification of novel lysosomal matrix proteins by proteome analysis”, Proteomics, vol. 5, 2005, pp. 3966-3978.PUB | DOI | WoS | PubMed | Europe PMC
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940085D. Hartmann, et al., “The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts”, Human Molecular Genetics, vol. 11, 2002, pp. 2615-2624.PUB | DOI | WoS | PubMed | Europe PMC
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940103B. Hansske, et al., “Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId”, Journal of Clinical Investigation, vol. 109, 2002, pp. 725-733.PUB | DOI | WoS | PubMed | Europe PMC
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940119T. Lübke, et al., “Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency”, Nature Genetics, vol. 28, 2001, pp. 73-76.PUB | DOI | WoS | PubMed | Europe PMC
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2001 | Dissertation | PUB-ID: 1940291T. Lübke, Congenital Disorder of Glycosylation (CDG)-IIc: Eine retrovirale Expressionsklonierung identifiziert das CDG-IIc Syndrom (Leukozyten Adhäsionsdefekt II) als eine GDP-Fukose Transporter Defizienz, Göttingen, Deutschland: Elektronische Dissertation der Georg-August-Universität Göttingen, 2001.PUB
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940146L.A. Andersson, et al., “ModE-dependent molybdate regulation of the molybdenum cofactor operon moa in Escherichia coli”, Journal of Bacteriology, vol. 182, 2000, pp. 7035-7043.PUB | DOI | WoS | PubMed | Europe PMC
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1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940173T. Lübke, et al., “A new type of carbohydrate-deficient glycoprotein syndrome due to a decreased import of GDP-fucose into the golgi”, Journal of Biological Chemistry, vol. 274, 1999, pp. 25986-25989.PUB | DOI | WoS | PubMed | Europe PMC