PUB - Publikationen an der Universität Bielefeld

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• [36]
  

  2025 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2993961

  Separation and Purification of CHO Secretome and Extracellular Vesicles for Proteome Analysis
  Lehmkuhl M, Keysberg C, Otte K, Noll T, Hoffrogge R (2025)
  In: Heterologous Protein Production in CHO Cells. Methods and Protocols. Meleady P (Ed); Methods in Molecular Biology. New York, NY: Springer US: 155-171.

  PUB | DOI | PubMed | Europe PMC
   
• [35]
  

  2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2985112

  Hyperthermic shift and cell engineering increase small extracellular vesicle production in HEK293F cells
  Keysberg C, Hertel O, Hoffrogge R, Reich S, Hornung N, Holzmann K, Otte K (2023)
  Biotechnology and Bioengineering.

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• [34]
  

  2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2962620

  Genetically Encoded Ratiometric pH Sensors for the Measurement of Intra- and Extracellular pH and Internalization Rates
  Karsten L, Gött-Zink L, Schmitz J, Hoffrogge R, Grünberger A, Kottke T, Müller K (2022)
  Biosensors 12(5): 271.

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• [33]
  

  2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2962032

  Hyperosmolality in CHO cell culture: effects on the proteome
  Romanova N, Schelletter L, Hoffrogge R, Noll T (2022)
  Applied Microbiology and Biotechnology 106: 2569–2586.

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• [32]
  

  2022 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2968503

  rAAV production revisited - from plasmid design to nanopore sequencing and proteomics
  Radukic M, Le DT, Golm SK, Rothschild C, Hoffrogge R, Müller K (2022)
  In: ESGCT 29th Annual Congress. In collaboration with BSGCT Edinburgh, UK October 11–14, 2022, Abstractss. Human Gene Therapy, 33(23-24). Mary Ann Liebert: A101.

  PUB | DOI | WoS
   
• [31]
  

  2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2961212

  Human Coxsackie- and adenovirus receptor is a putative target of neutrophil elastase-mediated shedding
  Herrmann L, Schelletter L, Hoffrogge R, Niehaus K, Rudolph V, Farr M (2022)
  Molecular Biology Reports .

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• [30]
  

  2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2954736

  Exploring the molecular content of CHO exosomes during bioprocessing
  Keysberg C, Hertel O, Schelletter L, Busche T, Sochart C, Kalinowski J, Hoffrogge R, Otte K, Noll T (2021)
  Applied Microbiology and Biotechnology 105(9): 3673-3689.

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• [29]
  

  2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2944311

  A Positive Pressure Workstation for Semi Automated Peptide Purification of Complex Proteomic Samples.
  Schelletter L, Hertel O, Antar SJ, Scherling C, Lattig J, Noll T, Hoffrogge R (2020)
  Rapid communications in mass spectrometry 35(2): e8873.

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• [28]
  

  2020 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2945942

  Impact of NaBu and RA on histones and nuclear signaling in CHO cells
  Pries A, Brachtvogel L, Noll T, Hoffrogge R (2020)
  BMC Proceedings 14(Suppl 5): P-159.

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• [27]
  

  2020 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2945943

  Media supplement induced signaling in CHO cells via triple SILAC-MS
  Schelletter L, Noll T, Hoffrogge R (2020)
  BMC Proceedings 14(Suppl 5): P-565.

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• [26]
  

  2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2937250

  Clonal variations in CHO IGF signaling investigated by SILAC-based phosphoproteomics and LFQ-MS
  Schelletter L, Albaum S, Walter S, Noll T, Hoffrogge R (2019)
  Applied microbiology and biotechnology 103(19): 8127-8143.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [25]
  

  2018 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2945946

  MS-SILAC approach for phosphoproteomics of IGF signaling in producer CHO cells
  Brachtvogel L, Walter S, Noll T, Hoffrogge R (2018)
  BMC Proceedings 12( Suppl. 1): 3.

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• [24]
  

  2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2911396

  Label-free protein quantification of sodium butyrate treated CHO cells by ESI-UHR-TOF-MS
  Müller B, Heinrich C, Jabs W, Kaspar-Schönefeld S, Schmidt A, Wehmeier N, Albaum S, Baessmann C, Noll T, Hoffrogge R (2017)
  Journal of Biotechnology 257: 87-98.

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• [23]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2907079

  Integrative analysis of DNA methylation and gene expression in butyrate-treated CHO cells
  Wippermann A, Rupp O, Brinkrolf K, Hoffrogge R, Noll T (2016)
  Journal of Biotechnology 257: 150-161.

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• [22]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2763691

  Process boundaries of irreversible scCO2 -assisted phase separation in biphasic whole-cell biocatalysis
  Brandenbusch C, Glonke S, Collins J, Hoffrogge R, Grunwald K, Bühler B, Schmidt A, Sadowski G (2015)
  Biotechnology and Bioengineering 112(11): 2316-2323.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [21]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2718767

  2D-DIGE screening of high-productive CHO cells under glucose limitation — Basic changes in the proteome equipment and hints for epigenetic effects
  Wingens M, Gätgens J, Schmidt A, Albaum S, Büntemeyer H, Noll T, Hoffrogge R (2015)
  Journal of Biotechnology 201: 86-97.

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• [20]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2718773

  The DNA methylation landscape of Chinese hamster ovary (CHO) DP-12 cells
  Wippermann A, Rupp O, Brinkrolf K, Hoffrogge R, Noll T (2015)
  Journal of Biotechnology 199: 38-46.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [19]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2656819

  Establishment of a CpG island microarray for analyses of genome-wide DNA methylation in Chinese hamster ovary cells
  Wippermann A, Klausing S, Rupp O, Albaum S, Büntemeyer H, Noll T, Hoffrogge R (2014)
  Applied Microbiology and Biotechnology 98(2): 579-589.

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• [18]
  

  2014 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2694187

  Functional -Omics for Cell Lines and Processes - The -Omics Technologies on the Example of CHO Cells
  Brinkrolf K, Hoffrogge R, Hackl M, Tauch A, Baumann M, Noll T, Goesmann A, Pühler A, Borth N (2014)
  In: Animal Cell Biotechnology In Biologics Production. Hauser H, Wagner R (Eds); Berlin, Germany: Walter de Gruyter: 702.

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• [17]
  

  2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2424989

  Effects of high passage cultivation on CHO cells: a global analysis
  Beckmann T, Krämer O, Klausing S, Heinrich C, Thüte T, Büntemeyer H, Hoffrogge R, Noll T (2012)
  Applied Microbiology Biotechnology 94(3): 659-671.

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• [16]
  

  2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2501364

  Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics
  Meleady P, Hoffrogge R, Henry M, Rupp O, Bort JH, Clarke C, Brinkrolf K, Kelly S, Müller B, Doolan P, Hackl M, et al. (2012)
  Biotechnology and Bioengineering 109(6): 1386-1394.

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• [15]
  

  2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2442810

  Analysis of the mitochondrial subproteome of the human cell line AGE1.HN – a contribution to a systems biology approach
  Skerhutt EM, Scholz S, Sandig V, Hoffrogge R, Noll T (2011)
  BMC Proceedings 5(8).

  PUB | DOI | PubMed | Europe PMC
   
• [14]
  

  2010 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2396497

  Proteomic characterization of a glucose-limited CHO perfusion process-analysis of metabolic changes and increase in productivity
  Wingens M, Gätgens J, Hoffrogge R, Noll T (2010)
  In: ESACT Proceedings. Noll T, European Society of Animal Cell Technology (Eds); ESACT proceedings, 4. Dordrecht : Springer: 265-269.

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• [13]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1929340

  CellViCAM-Cell viability classification for animal cell cultures using dark field micrographs
  Burgemeister S, Nattkemper TW, Noll T, Hoffrogge R, Flaschel E (2010)
  JOURNAL OF BIOTECHNOLOGY 149(4): 310-316.

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• [12]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1590965

  Interferon-beta modulates protein synthesis in the central nervous system
  Beyer S, Raether G, Stadler K, Hoffrogge R, Scharf C, Rolfs A, Mix E, Strauss U (2009)
  JOURNAL OF NEUROIMMUNOLOGY 213(1-2): 31-38.

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• [11]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2424733

  2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells
  Hoffrogge R, Beyer S, Huebner R, Mikkat S, Mix E, Scharf C, Schmitz U, Pauleweit S, Berth M, Zubrzycki IZ, Christoph H, et al. (2007)
  Proteomics 7(1): 33-46.

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• [10]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631319

  Neuroproteomics in stem cell differentiation
  Beyer S, Mix E, Hoffrogge R, Luenser K, Voelker U, Rolfs A (2007)
  PROTEOMICS CLINICAL APPLICATIONS 1(11): 1513-1523.

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• [9]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2424869

  2-DE proteome analysis of a proliferating and differentiating human neuronal stem cell line (ReNcell VM)
  Hoffrogge R, Mikkat S, Scharf C, Christoph H, Beyer S, Pahnke J, Mix E, Berth M, Uhrmacher A, Zubrzycki IZ, Miljan E, et al. (2006)
  Proteomics 6(6): 1833-1847.

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• [8]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2424910

  2-DE proteomic profiling of neuronal stem cells
  Hoffrogge R, Beyer S, Völker U, Uhrmacher A, Rolfs A (2006)
  Neurodegenerative Diseases 3(1-2): 112-121.

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• [7]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2424915

  3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor Atorvastatin mediated effects depend on the activation status of target cells in PLP-EAE
  Mix E, Ibrahim SM, Pahnke J, Glass Ä, Mazon-Pelafz I, Lemcke S, Koczan D, Gimsa U, Bansemeyer S, Scheel T, Koropka T, et al. (2006)
  Journal of Autoimmunity 27(4): 251-265.

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• [6]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2457335

  Amine donor protein substrates for transglutaminase activity in Caenorhabditis elegans.
  Madi A, Hoffrogge R, Blasko B, Glocker MO, Fesus L (2004)
  Biochemical and Biophysical Research Communications 315(4): 1064-1069.

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• [5]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2457361

  Streptococcus pyogenes fibronectin-binding protein F2: expression profile, binding characteristics and impact on eukaryotic cell interactions.
  Kreikemeyer B, Oehmcke S, Nakata M, Hoffrogge R, Podbielski A (2004)
  Journal of Biological Chemistry 279(16): 15850-15859.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [4]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2457370

  Surface Plasmon Resonance Spectroscopy (SPR) interaction studies of the circadian controlled tomato LHCa4*1 (cab 11) protein with its promoter.
  Hoffrogge R, Mikschofsky H, Piechulla B (2003)
  Chronobiology International 20(4): 543-558.

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• [3]
  

  2002 | Dissertation | PUB-ID: 2457376

  Analyse von Promotorelementen und assoziierten DNA-Bindeproteinen der circadianen Lhc-Genexpression der Tomate (Lycopersicon esculentum Mill.).
  Hoffrogge R (2002) ; 1.
  Osnabrück (Germany): Der Andere Verlag.

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• [2]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2457389

  Ecotypic and allozyme variation of Capsella bursa-pastoris and C. rubella (Brassicaceae) along latidude and altitude gradiends on the Iberian Peninsula.
  Neuffer B, Hoffrogge R (2000)
  Anales del Jardín Botánico de Madrid 57((2): 299-315.

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• [1]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2457393

  Transcriptional regulation of oscillating steady-state Lhc mRNA levels: characterization of two Lhca promotor fragments in transgenic tobacco plants.
  Kellmann J-W, Hoffrogge R, Piechulla B (1999)
  Biological Rhythm Research 30(3): 264-271.

  PUB