Thomas Noll

thomas.noll@uni-bielefeld.de
ORCID logo https://orcid.org/0000-0003-0748-3423

PEVZ-ID
163841

100 Publikationen

Alle markieren

  • [100]
    2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2979009 OA
    M. Klimpel, et al., “Development of a perfusion process for continuous lentivirus production using stable suspension producer cell lines”, Biotechnology and Bioengineering, 2023.
    PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
     
  • [99]
    2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2962032 OA
    N. Romanova, et al., “Hyperosmolality in CHO cell culture: effects on the proteome”, Applied Microbiology and Biotechnology, vol. 106, 2022, pp. 2569–2586.
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  • [98]
    2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2963556 OA
    N. Romanova, et al., “Single-Cell Analysis of CHO Cells Reveals Clonal Heterogeneity in Hyperosmolality-Induced Stress Response”, Cells, vol. 11, 2022, : 1763.
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  • [97]
    2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2966624 OA
    O. Hertel, et al., “Enhancing stability of recombinant CHO cells by CRISPR/Cas9-mediated site-specific integration into regions with distinct histone modifications”, Frontiers in Bioengineering and Biotechnology, vol. 10, 2022.
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  • [96]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2952449 OA
    K.E. Witte, et al., “Nanopore Sequencing Reveals Global Transcriptome Signatures of Mitochondrial and Ribosomal Gene Expressions in Various Human Cancer Stem-like Cell Populations”, Cancers, vol. 13, 2021, : 1136.
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  • [95]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2954736 OA
    C. Keysberg, et al., “Exploring the molecular content of CHO exosomes during bioprocessing”, Applied Microbiology and Biotechnology, vol. 105, 2021, pp. 3673-3689.
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  • [94]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2955090 OA
    J. Schmitz, et al., “Growth and eGFP-production of CHO-K1 suspension cells cultivated from single-cell to laboratory scale”, Frontiers in Bioengineering and Biotechnology, vol. 9, 2021, : 716343.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC | Preprint
     
  • [93]
    2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2953580 OA
    D. Budde, et al., “Interaction of leachable model compounds and their impact on Chinese hamster ovary cell cultivation”, Biotechnology Progress, 2021, : e3150.
    PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
     
  • [92]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2952639 OA
    N. Romanova, et al., “Hyperosmolality in CHO Culture: Effects on cellular behavior and morphology”, Biotechnology and Bioengineering, vol. 118, 2021, pp. 2348-2359.
    PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
     
  • [91]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949089 OA
    J. Schmitz, et al., “Development and application of a cultivation platform for mammalian suspension cell lines with single-cell resolution”, Biotechnology and Bioengineering, vol. 118, 2021, pp. 992-1005.
    PUB | Dateien verfügbar | DOI | WoS | PubMed | Europe PMC | Preprint
     
  • [90]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2944311 OA
    L. Schelletter, et al., “A Positive Pressure Workstation for Semi Automated Peptide Purification of Complex Proteomic Samples.”, Rapid communications in mass spectrometry, vol. 35, 2020, : e8873.
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  • [89]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2948753
    R. Beatson, et al., “Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype”, Communications biology, vol. 3, 2020, : 644.
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  • [88]
    2020 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2945942
    A. Pries, et al., “Impact of NaBu and RA on histones and nuclear signaling in CHO cells”, BMC Proceedings, vol. 14, 2020, : P-159.
    PUB
     
  • [87]
    2020 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2945943
    L. Schelletter, T. Noll, and R. Hoffrogge, “Media supplement induced signaling in CHO cells via triple SILAC-MS”, BMC Proceedings, vol. 14, 2020, : P-565.
    PUB
     
  • [86]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2945107 OA
    J. Coronel, et al., “Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode”, Frontiers in Bioengineering and Biotechnology, vol. 8, 2020, : 672.
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  • [85]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2944324
    D. Budde, et al., “Identification and evaluation of cell- growth-inhibiting bDtBPP-analogue degradation products from phosphite antioxidants used in polyolefin bioprocessing materials.”, Analytical and bioanalytical chemistry, vol. 412, 2020, pp. 4505-4518.
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  • [84]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2936490
    B. Seeger, et al., “Assessment of mixture toxicity of (tri)azoles and their hepatotoxic effects in vitro by means of omics technologies.”, Archives of toxicology, vol. 93, 2019, pp. 2321-2333.
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  • [83]
    2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2934600
    F. Krattenmacher, et al., “Effect of manufacturing temperature and storage duration on stability of chemically defined media measured with LC-MS/MS”, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, vol. 94, 2019, pp. 1144-1155.
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  • [82]
    2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2938369
    J. Coronel, et al., “Perfusion process combining low temperature and valeric acid for enhanced recombinant factor VIII production.”, Biotechnology progress, vol. 36, 2019, pp. e2915.
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  • [81]
    2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2937250
    L. Schelletter, et al., “Clonal variations in CHO IGF signaling investigated by SILAC-based phosphoproteomics and LFQ-MS”, Applied microbiology and biotechnology, vol. 103, 2019, pp. 8127-8143.
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  • [80]
    2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2933358
    J. Schmitz, T. Noll, and A. Grünberger, “Heterogeneity Studies of Mammalian Cells for Bioproduction. From Tools to Application”, Trends in Biotechnology, vol. 37, 2019, pp. 645-660.
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  • [79]
    2018 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2945946
    L. Brachtvogel, et al., “MS-SILAC approach for phosphoproteomics of IGF signaling in producer CHO cells”, BMC Proceedings, vol. 12, 2018, : 3.
    PUB
     
  • [78]
    2018 | Konferenzbeitrag | PUB-ID: 2933363
    J. Schmitz, T. Noll, and A. Grünberger, “Towards Microfluidic Single-Cell Cultivation of Mammalian Cell Lines”, Presented at the Young Scientist Cell Culture Biotechnology Retreat, Laupheim, 2018.
    PUB
     
  • [77]
    2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933359
    J. Schmitz, et al., “Towards dynamic single-cell cultivation systems for industrially relevant mammalian cell lines”, Presented at the BioProcessing Days 2018, Recklinghausen, 2018.
    PUB
     
  • [76]
    2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933362
    J. Schmitz, et al., “Dynamic microfluidical single-cell cultivation of mammalian cell lines. From experiment to analysis”, Presented at the CeBiTec Symposium 2018, Bielefeld, 2018.
    PUB
     
  • [75]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2915619
    N. Romanova and T. Noll, “Engineered and Natural Promoters and Chromatin-Modifying Elements for Recombinant Protein Expression in CHO Cells”, Biotechnology Journal, vol. 13, 2017, : e1700232.
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  • [74]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2911396
    B. Müller, et al., “Label-free protein quantification of sodium butyrate treated CHO cells by ESI-UHR-TOF-MS”, Journal of Biotechnology, vol. 257, 2017, pp. 87-98.
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  • [73]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2914045
    A. Wippermann and T. Noll, “DNA methylation in CHO cells”, Journal of Biotechnology, vol. 258, 2017, pp. 206-210.
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  • [72]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906640
    J. Coronel, et al., “Valeric acid supplementation combined to mild hypothermia increases productivity in CHO cell cultivations”, Biochemical Engineering Journal, vol. 114, 2016, pp. 101-109.
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  • [71]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2907079
    A. Wippermann, et al., “Integrative analysis of DNA methylation and gene expression in butyrate-treated CHO cells”, Journal of Biotechnology, vol. 257, 2016, pp. 150-161.
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  • [70]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906641
    R. Beatson, et al., “The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9”, Nature Immunology, vol. 17, 2016, pp. 1273-1281.
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  • [69]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2718767
    M. Wingens, et al., “2D-DIGE screening of high-productive CHO cells under glucose limitation — Basic changes in the proteome equipment and hints for epigenetic effects”, Journal of Biotechnology, vol. 201, 2015, pp. 86-97.
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  • [68]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2718773
    A. Wippermann, et al., “The DNA methylation landscape of Chinese hamster ovary (CHO) DP-12 cells”, Journal of Biotechnology, vol. 199, 2015, pp. 38-46.
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  • [67]
    2015 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2902782
    C. Knebel, et al., “Multi-level omics analysis of combination effects of (tri-)azoles in a set of different cell lines”, Toxicology Letters, vol. 238, 2015, pp. S355.
    PUB | DOI | WoS
     
  • [66]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2656819
    A. Wippermann, et al., “Establishment of a CpG island microarray for analyses of genome-wide DNA methylation in Chinese hamster ovary cells”, Applied Microbiology and Biotechnology, vol. 98, 2014, pp. 579-589.
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  • [65]
    2014 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2694187
    K. Brinkrolf, et al., “Functional -Omics for Cell Lines and Processes - The -Omics Technologies on the Example of CHO Cells”, Animal Cell Biotechnology In Biologics Production, H. Hauser and R. Wagner, eds., Berlin, Germany: Walter de Gruyter, 2014, pp.702.
    PUB
     
  • [64]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2685988
    T. Jakobi, et al., “Discovery of transcription start sites in the Chinese hamster genome by next-generation RNA sequencing”, Journal of Biotechnology, vol. 190, 2014, pp. 64-75.
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  • [63]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2676552
    J. Becker, et al., “Transcriptome analyses of CHO cells with the next-generation microarray CHO41K: Development and validation by analysing the influence of the growth stimulating substance IGF-1 substitute LongR(3.)”, Journal of biotechnology, vol. 178, 2014, pp. 23-31.
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  • [62]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2701280
    T. Noll, et al., “The Genomics Revolution and its Impact on Future Biotechnology”, Journal of Biotechnology, vol. 190, 2014, : 1.
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  • [61]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2656773
    O. Rupp, et al., “Construction of a Public CHO Cell Line Transcript Database Using Versatile Bioinformatics Analysis Pipelines”, PLoS ONE, vol. 9, 2014, : e85568.
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  • [60]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2679670
    A.G. Rath, et al., “The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells”, Journal of Biotechnology, vol. 178, 2014, pp. 43-53.
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  • [59]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2615581
    K. Brinkrolf, et al., “Chinese hamster genome sequenced from sorted chromosomes”, Nature Biotechnology, vol. 31, 2013, pp. 694-695.
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  • [58]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2577265 OA
    C. Klenke, et al., “Hsc70 is a novel interactor of NF-kappaB p65 in living hippocampal neurons”, PLoS ONE, vol. 8, 2013, : e65280.
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  • [57]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2351519
    J. Lenger, et al., “Evaluation of sulfatase-directed quinone methide traps for proteomics”, Bioorganic & Medicinal Chemistry, vol. 20, 2012, pp. 622-627.
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  • [56]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2553404
    M.J.T. Carrondo, et al., “How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?”, Biotechnology Journal, vol. 7, 2012, pp. 1522-1529.
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  • [55]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2424989
    T. Beckmann, et al., “Effects of high passage cultivation on CHO cells: a global analysis”, Applied Microbiology Biotechnology, vol. 94, 2012, pp. 659-671.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [54]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2501364
    P. Meleady, et al., “Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics”, Biotechnology and Bioengineering, vol. 109, 2012, pp. 1386-1394.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [53]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2478526
    M. Hackl, et al., “Computational identification of microRNA gene loci and precursor microRNA sequences in CHO cell lines”, Journal of Biotechnology, vol. 158, 2012, pp. 151-155.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [52]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2544205
    O.P. Barradas, et al., “Evaluation of criteria for bioreactor comparison and operation standardization for mammalian cell culture”, Engineering In Life Sciences, vol. 12, 2012, pp. 518-528.
    PUB | DOI | WoS
     
  • [51]
    2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2375038
    T. Beckmann, et al., “Proteomic and metabolomic characterization of CHO DP-12 cell lines with different high passage histories”, BMC Proceedings, vol. 5, 2011, : P92.
    PUB | DOI | PubMed | Europe PMC
     
  • [50]
    2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2375605
    S. Klausing, O. Krämer, and T. Noll, “Bioreactor cultivation of CHO DP-12 cells under sodium butyrate treatment – comparative transcriptome analysis with CHO cDNA microarrays”, BMC Proceedings, vol. 5, 2011, : P98 .
    PUB | DOI | PubMed | Europe PMC
     
  • [49]
    2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2453760
    C. Heinrich, et al., “Growth characterization of CHO DP-12 cell lines with different high passage histories”, BMC Proceedings, H. Hansjörg, ed., BMC Proceedings, vol. 5, BioMed Central, 2011.
    PUB | DOI | PubMed | Europe PMC
     
  • [48]
    2011 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2453768
    J. Becker, et al., “Next-generation sequencing of the CHO cell transcriptome”, BMC Proceedings, vol. 5, 2011, pp. P6.
    PUB | DOI
     
  • [47]
    2011 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2453752
    M. Volmer, et al., “A method for metabolomic sampling of suspended animal cells using fast filtration”, BMC Proceedings, vol. 5, 2011, pp. 95.
    PUB | DOI | PubMed | Europe PMC
     
  • [46]
    2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2442810
    E.M. Skerhutt, et al., “Analysis of the mitochondrial subproteome of the human cell line AGE1.HN – a contribution to a systems biology approach”, BMC Proceedings, vol. 5, 2011.
    PUB | DOI | PubMed | Europe PMC
     
  • [45]
    2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2442843
    E.M. Skerhutt, et al., “Characterisation of cultivation of the human cell line AGE1.HN.AAT”, BMC Proceedings, vol. 5, 2011.
    PUB | DOI | PubMed | Europe PMC
     
  • [44]
    2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2447643
    S. Scholz, et al., “Characterization of the human AGE1.HN cell line: a systems biology approach”, BMC Proceedings, vol. 5, 2011.
    PUB | DOI | PubMed | Europe PMC
     
  • [43]
    2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2447654
    O. Platas Barradas, et al., “Criteria for bioreactor comparison and operation standardisation during process development for mammalian cell culture”, BMC Proceedings, vol. 5, 2011.
    PUB | DOI | PubMed | Europe PMC
     
  • [42]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2289895
    J. Niklas, et al., “Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis”, Bioprocess and Biosystems Engineering, vol. 34, 2011, pp. 533-545.
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  • [41]
    2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2375051
    C. Heinrich, et al., “Utilization of multifrequency permittivity measurements in addition to biomass monitoring”, BMC Proceedings, vol. 5, 2011.
    PUB | DOI | PubMed | Europe PMC
     
  • [40]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2396576
    J. Becker, et al., “Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing”, Journal of Biotechnology, vol. 156, 2011, pp. 227-235.
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  • [39]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2094364
    M. Volmer, et al., “Fast filtration for metabolome sampling of suspended animal cells”, Biotechnology Letters, vol. 33, 2011, pp. 495-502.
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  • [38]
    2010 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2396494
    T. Nottorf, et al., “An integrated production process for human growth hormone”, ESACT Proceedings, T. Noll and European Society of Animal Cell Technology, eds., ESACT proceedings, vol. 4, Dordrecht : Springer, 2010, pp.205-208.
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  • [37]
    2010 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2396499
    M. Bäckström, et al., “O-glycans on recombinant MUC1 produced in CHO K1 cells becomes less sialylated with increased productivity as determined by LC ESI MS”, ESACT Proceedings, T. Noll and European Society of Animal Cell Technology, eds., ESACT proceedings, vol. 4, Dordrecht : Springer, 2010, pp.285-288.
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  • [36]
    2010 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2396502
    C. Wiendahl, et al., “Metabolome analysis in mammalian cells: Development and application of a sampling technique”, ESACT Proceedings, T. Noll and European Society of Animal Cell Technology, eds., ESACT proceedings, vol. 4, Dordrecht: Springer, 2010, pp.413-420.
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  • [35]
    2010 | Herausgeber*in Sammelwerk | Veröffentlicht | PUB-ID: 2453825
    T. Noll and European Society of Animal Cell Technology, eds., Cells and Culture, ESACT Proceedings, vol. 4, Dordrecht : Springer, 2010.
    PUB
     
  • [34]
    2010 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2396497
    M. Wingens, et al., “Proteomic characterization of a glucose-limited CHO perfusion process-analysis of metabolic changes and increase in productivity”, ESACT Proceedings, T. Noll and European Society of Animal Cell Technology, eds., ESACT proceedings, vol. 4, Dordrecht : Springer, 2010, pp.265-269.
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  • [33]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2396489
    O. Krämer, S. Klausing, and T. Noll, “Methods in mammalian cell line engineering: from random mutagenesis to sequence specific approaches”, Applied Microbiology and Biotechnology, vol. 88, 2010, pp. 425-436.
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  • [32]
    2010 | Konferenzbeitrag | PUB-ID: 2396573
    S. Northoff, et al., “Characterization of the novel human AGE1hn cell line for production of recombinant proteins”, ESACT Proceedings, T. Noll and European Society of Animal Cell Technology, eds., ESACT proceedings, vol. 4, Dordrecht : Spinger, 2010, pp.693-697.
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  • [31]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1929340
    S. Burgemeister, et al., “CellViCAM-Cell viability classification for animal cell cultures using dark field micrographs”, JOURNAL OF BIOTECHNOLOGY, vol. 149, 2010, pp. 310-316.
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  • [30]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1590674
    D. Widera, et al., “Adult Palatum as a Novel Source of Neural Crest-Related Stem Cells”, Stem Cells, vol. 27, 2009, pp. 1899-1910.
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  • [29]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2396483
    T. Kubitzki, et al., “Application of immobilized bovine enterokinase in repetitive fusion protein cleavage for the production of MUC1”, Journal of Biotechnology, vol. 4, 2009, pp. 1610-1618.
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  • [28]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395472
    S. Magin, et al., “Primary cells as feeder cells for clinical co-culture expansion of human hematopoietic stem cells from umbilical cord blood – a comparative study”, Stem Cell and Development, vol. 18, 2009, pp. 173-186.
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  • [27]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395445
    C. Sihlbom, et al., “Localisation of O-glycans in MUC1 glycoproteins using electron-capture dissociation fragmentation mass spectrometry”, Glycobiology, vol. 19, 2009, pp. 375-381.
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  • [26]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1633988
    F.R.X. Batista, et al., “Influence of culture conditions on recombinant Drosophila melanogaster S2 cells producing rabies virus glycoprotein cultivated in serum-free medium”, BIOLOGICALS, vol. 37, 2009, pp. 108-118.
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  • [25]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1592705
    M.J. Grimshaw, et al., “Immunisation with 'naive' syngeneic dendritic cells protects mice from tumour challenge”, British Journal of Cancer, vol. 98, 2008, pp. 784-791.
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  • [24]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1592236
    T. Kubitzki, T. Noll, and S. Luetz, “Immobilisation of bovine enterokinase and application of the immobilised enzyme in fusion protein cleavage”, BIOPROCESS AND BIOSYSTEMS ENGINEERING, vol. 31, 2008, pp. 173-182.
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  • [23]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1595232
    C. Wiendahl, et al., “A microstructure heat exchanger for quenching the metabolism of mammalian cells”, CHEMICAL ENGINEERING & TECHNOLOGY, vol. 30, 2007, pp. 322-328.
    PUB | DOI | WoS
     
  • [22]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395430
    U. Brockmeier, et al., “Systematic Screening of All Signal Peptides from Bacillus subtilis: A Powerful Strategy in Optimizing Heterologous Protein Secretion in Gram-positive Bacteria”, Journal of Molecular Biology, vol. 362, 2006, pp. 393-402.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [21]
    2006 | Zeitschriftenaufsatz | PUB-ID: 2395413
    R. Sewell, et al., “Human ST6GalNAcI localizes throughout the Golgi and is responsible for the expression of the sialyl-Tn O-glycan in breast cancers”, Journal of Biological Chemistry, vol. 281, 2006, pp. 3586-3594.
    PUB
     
  • [20]
    2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2395377
    H. Bohnenkamp and T. Noll, “Process development for standardized generation of monocyte-derived dendritic cells: Applicability in breast cancer immunotherapy”, ESACT Proceedings, vol. 2, Springer, 2005, pp.221-227.
    PUB
     
  • [19]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395286
    H. Bohnenkamp, et al., “Apoptosis of monocytes and the influence on yield of monocyte-derived dendritic cells”, Journal of Immunological Methods, vol. 294, 2005, pp. 67-80.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [18]
    2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2395363
    K. Fischbach and T. Noll, “Membrane-separated cocultivation of cord blood hematopoietic stem cells with stromal cell lines”, ESACT Proceedings, vol. 2, Springer, 2005, pp.269-271.
    PUB
     
  • [17]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395387
    A. Rughetti, et al., “Recombinant tumor associated MUC1 impairs differentiation and function of Dendritic Cells”, Journal of Immunology, vol. 174, 2005, pp. 7764-7772.
    PUB
     
  • [16]
    2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2395311
    T. Link, et al., “Development of metabolically optimized fermentation process based on glucose-limited CHO perfusion culture”, ESACT Proceedings, vol. 2, Springer, 2005, pp.423-430.
    PUB
     
  • [15]
    2004 | Zeitschriftenaufsatz | PUB-ID: 2395241
    T. Link, et al., “Bioprocess development for a recombinant Mucin-1 fusion protein expressed by CHO cells in protein-free medium”, Journal of Biotechnology, vol. 110, 2004, pp. 51-62.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [14]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395163
    M. Bäckström, et al., “Recombinant MUC1 with breast cancer-like O-glycosylation produced in large amounts in CHO-K1 cells”, Biochemical Journal, vol. 376, 2003, pp. 677-686.
    PUB
     
  • [13]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395226
    T. Noll, “Stammzellen – Möglichkeiten ihrer Expansion am Beispiel hämatopoetischer Stammzellen aus Nabelschnurblut”, Med Klin, vol. 98, 2003, pp. 7-10.
    PUB
     
  • [12]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395236
    H. Bohnenkamp and T. Noll, “Process Development for standardized generation of mature monocyte-derived dendritic cells suitable for clinical application, Cytotechnology”, Cytotechnology, vol. 42, 2003, pp. 121-131.
    PUB
     
  • [11]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2394881
    T. Noll, et al., “Cultivation of Hematopoietic Stem and Progenitor Cells: Biochemical Engineering Aspects”, Advances in Biochemical Engineering and Biotechnology, vol. 74, 2002, pp. 111-128.
    PUB
     
  • [10]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2394913
    T. Noll, et al., “Improved product formation in high density Chinese hamster ovary cell cultures transfected at confluency”, Biotechnological letters, vol. 24, 2002, pp. 861-866.
    PUB
     
  • [9]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2394956
    H. Bohnenkamp, U. Hilbert, and T. Noll, “Bioprocess Development for the Cultivation of human T-lymphocytes in a clinical scale”, Cytotechnology, vol. 38, 2002, pp. 135-145.
    PUB
     
  • [8]
    2002 | Zeitschriftenaufsatz | PUB-ID: 2395110
    W. Paul, et al., “'Identifizierung von Stoffwechsellimitierungen mit Hilfe der metabolic flux analysis am Beispiel des Nukleotidstoffwechsels von rekombinanten BHK-Zellen”, Chemie Ingenieur Technik, vol. 74, 2002.
    PUB
     
  • [7]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395044
    T. Link, et al., “Integrierte Bioprozessentwicklung zur Produktion eines potentiellen Tumorvaccins in rekombinanten CHO-Zellen”, Chemie Ingenieur Technik, vol. 74, 2002.
    PUB
     
  • [6]
    2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2393293
    H. Bohnenkamp, U. Hilbert, and T. Noll, “Bioprocess Development for the cultivation of human T-lymphocytes”, Presented at the 17th European Society for Animal Cell Technology (ESACT) Meeting on Cell Based Technologies, Sweden, Kluwer Academic, 2001.
    PUB
     
  • [5]
    2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2394851
    W. Paul, et al., “Metabolic flux analysis in mammalian cells - network modelling as an example for metabolic design in recombinant BHK cells”, Presented at the 17th European Society for Animal Cell Technology (ESACT) Meeting on Cell Based Technologies, Sweden, Kluwer Academic, 2001.
    PUB
     
  • [4]
    2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2393315
    U. Hilbert, M. Biselli, and T. Noll, “Cultivation of human CMV-specific lymphocytes - an example for adoptive immunoterapy”, Presented at the 17th European Society for Animal Cell Technology (ESACT) Meeting on Cell Based Technologies, Sweden, Kluwer Academic, 2001.
    PUB
     
  • [3]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2393281
    T. Noll, “A cell culture reactor for the on-line evaluation of radiopharmaceuticals: Evaluation of the lumped constant of FDG in human glioma cells”, Journal of Nuclear Medicine, vol. 41, 2000, pp. 556-564.
    PUB
     
  • [2]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2393268
    T. Noll and B. M, “Dielectric spectroscopy in the cultivation of suspended and immobilized hybridoma cells.”, Journal of Biotechnology, vol. 63, 1998, pp. 187-198.
    PUB
     
  • [1]
    1997 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2393237
    T. Noll, M. Biselli, and C. Wandrey, “On-line biomass monitoring of immobilized hybridoma cells by dielectrical measurements”, Presented at the 14th European Society for Animal Cell Technology (ESACT) Meeting on Cell Based Technologies, Portugal, Kluwer, 1997.
    PUB
     
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