100 Publikationen
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2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2979009Klimpel, M., et al., 2023. Development of a perfusion process for continuous lentivirus production using stable suspension producer cell lines. Biotechnology and Bioengineering.PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2963556Romanova, N., et al., 2022. Single-Cell Analysis of CHO Cells Reveals Clonal Heterogeneity in Hyperosmolality-Induced Stress Response. Cells, 11(11): 1763.PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2966624Hertel, O., et al., 2022. Enhancing stability of recombinant CHO cells by CRISPR/Cas9-mediated site-specific integration into regions with distinct histone modifications. Frontiers in Bioengineering and Biotechnology, 10.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2952449Witte, K.E., et al., 2021. Nanopore Sequencing Reveals Global Transcriptome Signatures of Mitochondrial and Ribosomal Gene Expressions in Various Human Cancer Stem-like Cell Populations. Cancers, 13(5): 1136.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2955090Schmitz, J., et al., 2021. Growth and eGFP-production of CHO-K1 suspension cells cultivated from single-cell to laboratory scale. Frontiers in Bioengineering and Biotechnology, 9: 716343.PUB | PDF | DOI | WoS | PubMed | Europe PMC | Preprint
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2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2953580Budde, D., et al., 2021. Interaction of leachable model compounds and their impact on Chinese hamster ovary cell cultivation. Biotechnology Progress, : e3150.PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2952639Romanova, N., et al., 2021. Hyperosmolality in CHO Culture: Effects on cellular behavior and morphology. Biotechnology and Bioengineering, 118(6), p 2348-2359.PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949089Schmitz, J., et al., 2021. Development and application of a cultivation platform for mammalian suspension cell lines with single-cell resolution. Biotechnology and Bioengineering, 118(2), p 992-1005.PUB | Dateien verfügbar | DOI | WoS | PubMed | Europe PMC | Preprint
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2948753Beatson, R., et al., 2020. Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype. Communications biology, 3(1): 644.PUB | DOI | WoS | PubMed | Europe PMC
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2020 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2945942Pries, A., et al., 2020. Impact of NaBu and RA on histones and nuclear signaling in CHO cells. BMC Proceedings, 14(Suppl 5): P-159.PUB
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2020 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2945943Schelletter, L., Noll, T., & Hoffrogge, R., 2020. Media supplement induced signaling in CHO cells via triple SILAC-MS. BMC Proceedings, 14(Suppl 5): P-565.PUB
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2944324Budde, D., et al., 2020. Identification and evaluation of cell- growth-inhibiting bDtBPP-analogue degradation products from phosphite antioxidants used in polyolefin bioprocessing materials. Analytical and bioanalytical chemistry, 412(19), p 4505-4518.PUB | DOI | WoS | PubMed | Europe PMC
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2936490Seeger, B., et al., 2019. Assessment of mixture toxicity of (tri)azoles and their hepatotoxic effects in vitro by means of omics technologies. Archives of toxicology, 93(8), p 2321-2333.PUB | DOI | WoS | PubMed | Europe PMC
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2934600Krattenmacher, F., et al., 2019. Effect of manufacturing temperature and storage duration on stability of chemically defined media measured with LC-MS/MS. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 94(4), p 1144-1155.PUB | DOI | WoS
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2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2938369Coronel, J., et al., 2019. Perfusion process combining low temperature and valeric acid for enhanced recombinant factor VIII production. Biotechnology progress, 36(1), p e2915.PUB | DOI | WoS | PubMed | Europe PMC
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2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2937250Schelletter, L., et al., 2019. Clonal variations in CHO IGF signaling investigated by SILAC-based phosphoproteomics and LFQ-MS. Applied microbiology and biotechnology, 103(19), p 8127-8143.PUB | DOI | WoS | PubMed | Europe PMC
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2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2933358Schmitz, J., Noll, T., & Grünberger, A., 2019. Heterogeneity Studies of Mammalian Cells for Bioproduction. From Tools to Application. Trends in Biotechnology, 37(6), p 645-660.PUB | DOI | WoS | PubMed | Europe PMC
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2018 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2945946Brachtvogel, L., et al., 2018. MS-SILAC approach for phosphoproteomics of IGF signaling in producer CHO cells. BMC Proceedings, 12( Suppl. 1): 3.PUB
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2018 | Konferenzbeitrag | PUB-ID: 2933363Schmitz, J., Noll, T., & Grünberger, A., 2018. Towards Microfluidic Single-Cell Cultivation of Mammalian Cell Lines. Presented at the Young Scientist Cell Culture Biotechnology Retreat, Laupheim.PUB
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2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933359Schmitz, J., et al., 2018. Towards dynamic single-cell cultivation systems for industrially relevant mammalian cell lines. Presented at the BioProcessing Days 2018, Recklinghausen.PUB
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2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933362Schmitz, J., et al., 2018. Dynamic microfluidical single-cell cultivation of mammalian cell lines. From experiment to analysis. Presented at the CeBiTec Symposium 2018, Bielefeld.PUB
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2915619Romanova, N., & Noll, T., 2017. Engineered and Natural Promoters and Chromatin-Modifying Elements for Recombinant Protein Expression in CHO Cells. Biotechnology Journal, 13(3): e1700232.PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2911396Müller, B., et al., 2017. Label-free protein quantification of sodium butyrate treated CHO cells by ESI-UHR-TOF-MS. Journal of Biotechnology, 257, p 87-98.PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2914045Wippermann, A., & Noll, T., 2017. DNA methylation in CHO cells. Journal of Biotechnology, 258(SI), p 206-210.PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2907079Wippermann, A., et al., 2016. Integrative analysis of DNA methylation and gene expression in butyrate-treated CHO cells. Journal of Biotechnology, 257, p 150-161.PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906641Beatson, R., et al., 2016. The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9. Nature Immunology, 17(11), p 1273-1281.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2718767Wingens, M., et al., 2015. 2D-DIGE screening of high-productive CHO cells under glucose limitation — Basic changes in the proteome equipment and hints for epigenetic effects. Journal of Biotechnology, 201, p 86-97.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2718773Wippermann, A., et al., 2015. The DNA methylation landscape of Chinese hamster ovary (CHO) DP-12 cells. Journal of Biotechnology, 199, p 38-46.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2656819Wippermann, A., et al., 2014. Establishment of a CpG island microarray for analyses of genome-wide DNA methylation in Chinese hamster ovary cells. Applied Microbiology and Biotechnology, 98(2), p 579-589.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2694187Brinkrolf, K., et al., 2014. Functional -Omics for Cell Lines and Processes - The -Omics Technologies on the Example of CHO Cells. In H. Hauser & R. Wagner, eds. Animal Cell Biotechnology In Biologics Production. Berlin, Germany: Walter de Gruyter, pp. 702.PUB
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2685988Jakobi, T., et al., 2014. Discovery of transcription start sites in the Chinese hamster genome by next-generation RNA sequencing. Journal of Biotechnology, 190, p 64-75.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2676552Becker, J., et al., 2014. Transcriptome analyses of CHO cells with the next-generation microarray CHO41K: Development and validation by analysing the influence of the growth stimulating substance IGF-1 substitute LongR(3.). Journal of biotechnology, 178, p 23-31.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2701280Noll, T., et al., 2014. The Genomics Revolution and its Impact on Future Biotechnology. Journal of Biotechnology, 190: 1.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2656773Rupp, O., et al., 2014. Construction of a Public CHO Cell Line Transcript Database Using Versatile Bioinformatics Analysis Pipelines. PLoS ONE, 9(1): e85568.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2679670Rath, A.G., et al., 2014. The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells. Journal of Biotechnology, 178, p 43-53.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2615581Brinkrolf, K., et al., 2013. Chinese hamster genome sequenced from sorted chromosomes. Nature Biotechnology, 31(8), p 694-695.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2351519Lenger, J., et al., 2012. Evaluation of sulfatase-directed quinone methide traps for proteomics. Bioorganic & Medicinal Chemistry, 20(2), p 622-627.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2553404Carrondo, M.J.T., et al., 2012. How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? Biotechnology Journal, 7(12), p 1522-1529.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2424989Beckmann, T., et al., 2012. Effects of high passage cultivation on CHO cells: a global analysis. Applied Microbiology Biotechnology, 94(3), p 659-671.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2501364Meleady, P., et al., 2012. Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics. Biotechnology and Bioengineering, 109(6), p 1386-1394.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2478526Hackl, M., et al., 2012. Computational identification of microRNA gene loci and precursor microRNA sequences in CHO cell lines. Journal of Biotechnology, 158(3), p 151-155.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2375038Beckmann, T., et al., 2011. Proteomic and metabolomic characterization of CHO DP-12 cell lines with different high passage histories. BMC Proceedings, 5(Suppl 8): P92.PUB | DOI | PubMed | Europe PMC
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2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2375605Klausing, S., Krämer, O., & Noll, T., 2011. Bioreactor cultivation of CHO DP-12 cells under sodium butyrate treatment – comparative transcriptome analysis with CHO cDNA microarrays. BMC Proceedings, 5(Suppl 8): P98 .PUB | DOI | PubMed | Europe PMC
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2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2453760Heinrich, C., et al., 2011. Growth characterization of CHO DP-12 cell lines with different high passage histories. In H. Hansjörg, ed. BMC Proceedings. BMC Proceedings. no.5 BioMed Central.PUB | DOI | PubMed | Europe PMC
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2011 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2453752Volmer, M., et al., 2011. A method for metabolomic sampling of suspended animal cells using fast filtration. BMC Proceedings, 5(8), p 95.PUB | DOI | PubMed | Europe PMC
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2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2442810Skerhutt, E.M., et al., 2011. Analysis of the mitochondrial subproteome of the human cell line AGE1.HN – a contribution to a systems biology approach. BMC Proceedings, 5(8).PUB | DOI | PubMed | Europe PMC
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2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2442843Skerhutt, E.M., et al., 2011. Characterisation of cultivation of the human cell line AGE1.HN.AAT. BMC Proceedings, 5(8).PUB | DOI | PubMed | Europe PMC
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2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2447643Scholz, S., et al., 2011. Characterization of the human AGE1.HN cell line: a systems biology approach. BMC Proceedings, 5(8).PUB | DOI | PubMed | Europe PMC
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2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2447654Platas Barradas, O., et al., 2011. Criteria for bioreactor comparison and operation standardisation during process development for mammalian cell culture. BMC Proceedings, 5(8).PUB | DOI | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2289895Niklas, J., et al., 2011. Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis. Bioprocess and Biosystems Engineering, 34(5), p 533-545.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2375051Heinrich, C., et al., 2011. Utilization of multifrequency permittivity measurements in addition to biomass monitoring. BMC Proceedings, 5(Suppl 8).PUB | DOI | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2396576Becker, J., et al., 2011. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Journal of Biotechnology, 156(3), p 227-235.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2094364Volmer, M., et al., 2011. Fast filtration for metabolome sampling of suspended animal cells. Biotechnology Letters, 33(3), p 495-502.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2396494Nottorf, T., et al., 2010. An integrated production process for human growth hormone. In T. Noll & European Society of Animal Cell Technology, eds. ESACT Proceedings. ESACT proceedings. no.4 Dordrecht : Springer, pp. 205-208.PUB
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2010 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2396499Bäckström, M., et al., 2010. O-glycans on recombinant MUC1 produced in CHO K1 cells becomes less sialylated with increased productivity as determined by LC ESI MS. In T. Noll & European Society of Animal Cell Technology, eds. ESACT Proceedings. ESACT proceedings. no.4 Dordrecht : Springer, pp. 285-288.PUB
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2010 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2396502Wiendahl, C., et al., 2010. Metabolome analysis in mammalian cells: Development and application of a sampling technique. In T. Noll & European Society of Animal Cell Technology, eds. ESACT Proceedings. ESACT proceedings. no.4 Dordrecht: Springer, pp. 413-420.PUB | DOI
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2010 | Herausgeber*in Sammelwerk | Veröffentlicht | PUB-ID: 2453825T. Noll & European Society of Animal Cell Technology, eds., 2010. Cells and Culture, ESACT Proceedings, no.4, Dordrecht : Springer.PUB
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2010 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2396497Wingens, M., et al., 2010. Proteomic characterization of a glucose-limited CHO perfusion process-analysis of metabolic changes and increase in productivity. In T. Noll & European Society of Animal Cell Technology, eds. ESACT Proceedings. ESACT proceedings. no.4 Dordrecht : Springer, pp. 265-269.PUB
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2396489Krämer, O., Klausing, S., & Noll, T., 2010. Methods in mammalian cell line engineering: from random mutagenesis to sequence specific approaches. Applied Microbiology and Biotechnology, 88(2), p 425-436.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Konferenzbeitrag | PUB-ID: 2396573Northoff, S., et al., 2010. Characterization of the novel human AGE1hn cell line for production of recombinant proteins. In T. Noll & European Society of Animal Cell Technology, eds. ESACT Proceedings. ESACT proceedings. no.4 Dordrecht : Spinger, pp. 693-697.PUB
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1929340Burgemeister, S., et al., 2010. CellViCAM-Cell viability classification for animal cell cultures using dark field micrographs. JOURNAL OF BIOTECHNOLOGY, 149(4), p 310-316.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1590674Widera, D., et al., 2009. Adult Palatum as a Novel Source of Neural Crest-Related Stem Cells. Stem Cells, 27(8), p 1899-1910.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2396483Kubitzki, T., et al., 2009. Application of immobilized bovine enterokinase in repetitive fusion protein cleavage for the production of MUC1. Journal of Biotechnology, 4(11), p 1610-1618.PUB | DOI | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395472Magin, S., et al., 2009. Primary cells as feeder cells for clinical co-culture expansion of human hematopoietic stem cells from umbilical cord blood – a comparative study. Stem Cell and Development, 18(1), p 173-186.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395445Sihlbom, C., et al., 2009. Localisation of O-glycans in MUC1 glycoproteins using electron-capture dissociation fragmentation mass spectrometry. Glycobiology, 19(4), p 375-381.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1633988Batista, F.R.X., et al., 2009. Influence of culture conditions on recombinant Drosophila melanogaster S2 cells producing rabies virus glycoprotein cultivated in serum-free medium. BIOLOGICALS, 37(2), p 108-118.PUB | DOI | WoS | PubMed | Europe PMC
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1592705Grimshaw, M.J., et al., 2008. Immunisation with 'naive' syngeneic dendritic cells protects mice from tumour challenge. British Journal of Cancer, 98(4), p 784-791.PUB | DOI | WoS | PubMed | Europe PMC
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1592236Kubitzki, T., Noll, T., & Luetz, S., 2008. Immobilisation of bovine enterokinase and application of the immobilised enzyme in fusion protein cleavage. BIOPROCESS AND BIOSYSTEMS ENGINEERING, 31(3), p 173-182.PUB | DOI | WoS | PubMed | Europe PMC
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395430Brockmeier, U., et al., 2006. Systematic Screening of All Signal Peptides from Bacillus subtilis: A Powerful Strategy in Optimizing Heterologous Protein Secretion in Gram-positive Bacteria. Journal of Molecular Biology, 362(3), p 393-402.PUB | DOI | WoS | PubMed | Europe PMC
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2006 | Zeitschriftenaufsatz | PUB-ID: 2395413Sewell, R., et al., 2006. Human ST6GalNAcI localizes throughout the Golgi and is responsible for the expression of the sialyl-Tn O-glycan in breast cancers. Journal of Biological Chemistry, 281, p 3586-3594.PUB
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2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2395377Bohnenkamp, H., & Noll, T., 2005. Process development for standardized generation of monocyte-derived dendritic cells: Applicability in breast cancer immunotherapy. In ESACT Proceedings. no.2 Springer, pp. 221-227.PUB
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395286Bohnenkamp, H., et al., 2005. Apoptosis of monocytes and the influence on yield of monocyte-derived dendritic cells. Journal of Immunological Methods, 294(1-2), p 67-80.PUB | DOI | WoS | PubMed | Europe PMC
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2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2395363Fischbach, K., & Noll, T., 2005. Membrane-separated cocultivation of cord blood hematopoietic stem cells with stromal cell lines. In ESACT Proceedings. no.2 Springer, pp. 269-271.PUB
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395387Rughetti, A., et al., 2005. Recombinant tumor associated MUC1 impairs differentiation and function of Dendritic Cells. Journal of Immunology, 174(12), p 7764-7772.PUB
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2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2395311Link, T., et al., 2005. Development of metabolically optimized fermentation process based on glucose-limited CHO perfusion culture. In ESACT Proceedings. no.2 Springer, pp. 423-430.PUB
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2004 | Zeitschriftenaufsatz | PUB-ID: 2395241Link, T., et al., 2004. Bioprocess development for a recombinant Mucin-1 fusion protein expressed by CHO cells in protein-free medium. Journal of Biotechnology, 110(1), p 51-62.PUB | DOI | WoS | PubMed | Europe PMC
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395163Bäckström, M., et al., 2003. Recombinant MUC1 with breast cancer-like O-glycosylation produced in large amounts in CHO-K1 cells. Biochemical Journal, 376, p 677-686.PUB
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395226Noll, T., 2003. Stammzellen – Möglichkeiten ihrer Expansion am Beispiel hämatopoetischer Stammzellen aus Nabelschnurblut. Med Klin, 98(Suppl II), p 7-10.PUB
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395236Bohnenkamp, H., & Noll, T., 2003. Process Development for standardized generation of mature monocyte-derived dendritic cells suitable for clinical application, Cytotechnology. Cytotechnology, 42, p 121-131.PUB
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2394881Noll, T., et al., 2002. Cultivation of Hematopoietic Stem and Progenitor Cells: Biochemical Engineering Aspects. Advances in Biochemical Engineering and Biotechnology, 74, p 111-128.PUB
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2394913Noll, T., et al., 2002. Improved product formation in high density Chinese hamster ovary cell cultures transfected at confluency. Biotechnological letters, 24, p 861-866.PUB
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2394956Bohnenkamp, H., Hilbert, U., & Noll, T., 2002. Bioprocess Development for the Cultivation of human T-lymphocytes in a clinical scale. Cytotechnology, 38, p 135-145.PUB
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2002 | Zeitschriftenaufsatz | PUB-ID: 2395110Paul, W., et al., 2002. 'Identifizierung von Stoffwechsellimitierungen mit Hilfe der metabolic flux analysis am Beispiel des Nukleotidstoffwechsels von rekombinanten BHK-Zellen. Chemie Ingenieur Technik, 74(690).PUB
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2395044Link, T., et al., 2002. Integrierte Bioprozessentwicklung zur Produktion eines potentiellen Tumorvaccins in rekombinanten CHO-Zellen. Chemie Ingenieur Technik, 74(671).PUB
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2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2393293Bohnenkamp, H., Hilbert, U., & Noll, T., 2001. Bioprocess Development for the cultivation of human T-lymphocytes. Presented at the 17th European Society for Animal Cell Technology (ESACT) Meeting on Cell Based Technologies, Sweden.PUB
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2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2394851Paul, W., et al., 2001. Metabolic flux analysis in mammalian cells - network modelling as an example for metabolic design in recombinant BHK cells. Presented at the 17th European Society for Animal Cell Technology (ESACT) Meeting on Cell Based Technologies, Sweden.PUB
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2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2393315Hilbert, U., Biselli, M., & Noll, T., 2001. Cultivation of human CMV-specific lymphocytes - an example for adoptive immunoterapy. Presented at the 17th European Society for Animal Cell Technology (ESACT) Meeting on Cell Based Technologies, Sweden.PUB
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2393281Noll, T., 2000. A cell culture reactor for the on-line evaluation of radiopharmaceuticals: Evaluation of the lumped constant of FDG in human glioma cells. Journal of Nuclear Medicine, 41(3), p 556-564.PUB
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1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2393268Noll, T., & M, B., 1998. Dielectric spectroscopy in the cultivation of suspended and immobilized hybridoma cells. Journal of Biotechnology, 63, p 187-198.PUB
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1997 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2393237Noll, T., Biselli, M., & Wandrey, C., 1997. On-line biomass monitoring of immobilized hybridoma cells by dielectrical measurements. Presented at the 14th European Society for Animal Cell Technology (ESACT) Meeting on Cell Based Technologies, Portugal.PUB