93 Publikationen

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  • [93]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904075
    Müller, J., Risse, J. M., Jussen, D., & Flaschel, E. (2016). Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies (vol 163, pg 325, 2013). JOURNAL OF BIOTECHNOLOGY, 226, 76-77. doi:10.1016/j.jbiotec.2016.03.048
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  • [92]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906183
    Schulte, F., Flaschel, E., & Niehaus, K. (2016). Proteome-Based Analysis of Colloidal Instability Enables the Detection of Haze-Active Proteins in Beer. Journal of Agricultural and Food Chemistry, 64(35), 6752-6761. doi:10.1021/acs.jafc.6b02467
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  • [91]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903023
    Wetzel, D., Müller, J., Flaschel, E., Friehs, K., & Risse, J. M. (2016). Fed-batch production and secretion of streptavidin by Hansenula polymorpha: Evaluation of genetic factors and bioprocess development. JOURNAL OF BIOTECHNOLOGY, 225, 3-9. doi:10.1016/j.jbiotec.2016.03.017
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  • [90]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906197
    Müller, J., Bruhn, S., Flaschel, E., Friehs, K., & Risse, J. M. (2016). GAP promoter-based fed-batch production of highly bioactive core streptavidin by Pichia pastoris. BIOTECHNOLOGY PROGRESS, 32(4), 855-864. doi:10.1002/btpr.2283
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  • [89]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2900637
    Müller, J., Wetzel, D., Flaschel, E., Friehs, K., & Risse, J. M. (2016). Constitutive production and efficient secretion of soluble full-length streptavidin by an Escherichia coli 'leaky mutant'. Journal of Biotechnology, 221, 91-100. doi:10.1016/j.jbiotec.2016.01.032
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  • [88]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2767378
    Müller, J., Risse, J. M., Friehs, K., & Flaschel, E. (2015). Model-based development of an assay for the rapid detection of biotin-blocked binding sites of streptavidin. Engineering in Life Sciences, 15(6), 627-639. doi:10.1002/elsc.201400227
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  • [87]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759080
    Grimm, P., Risse, J. M., Müller, J., Cholewa, D., Beshay, U., Friehs, K., & Flaschel, E. (2015). Applicability of Euglena gracilis for biorefineries demonstrated by the production of α-tocopherol and paramylon followed by anaerobic digestion. Journal of Biotechnology, 215, 72-79. doi:10.1016/j.jbiotec.2015.04.004
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  • [86]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2722001
    Schwarzhans, J. P., Cholewa, D., Grimm, P., Beshay, U., Risse, J. M., Friehs, K., & Flaschel, E. (2015). Dependency of the fatty acid composition of Euglena gracilis on growth phase and culture conditions. Journal of Applied Phycology, 27(4), 1389-1399. doi:10.1007/s10811-014-0458-4
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  • [85]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2679910 OA
    Selvamani, R. S. V., Telaar, M., Friehs, K., & Flaschel, E. (2014). Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA). Microbial Cell Factories, 13(1), 58. doi:10.1186/1475-2859-13-58
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  • [84]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2675672
    Selvamani, R. S. V., Friehs, K., & Flaschel, E. (2014). Extracellular recombinant protein production under continuous culture conditions with Escherichia coli using an alternative plasmid selection mechanism. Bioprocess and Biosystems Engineering, 37(3), 401-413. doi:10.1007/s00449-013-1005-4
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  • [83]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2551139
    Müller, J. M., Risse, J. M., Jussen, D., & Flaschel, E. (2013). Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies. Journal of Biotechnology, 163(3), 325-332. doi:10.1016/j.jbiotec.2012.10.021
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [82]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945165
    Vijayendran, C., & Flaschel, E. (2010). Impact of profiling technologies in the understanding of recombinant protein production. Adv Biochem Eng Biotechnol, 121, 45-70. https://doi.org/10.1007/10_2009_56
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  • [81]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1929340
    Burgemeister, S., Nattkemper, T. W., Noll, T., Hoffrogge, R., & Flaschel, E. (2010). CellViCAM-Cell viability classification for animal cell cultures using dark field micrographs. JOURNAL OF BIOTECHNOLOGY, 149(4), 310-316. https://doi.org/10.1016/j.jbiotec.2010.07.020
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  • [80]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796536
    Sommer, B., Friehs, K., & Flaschel, E. (2010). Efficient production of extracellular proteins with Escherichia coli by means of optimized coexpression of bacteriocin release proteins. JOURNAL OF BIOTECHNOLOGY, 145(4), 350-358. https://doi.org/10.1016/j.jbiotec.2009.11.019
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  • [79]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1795042
    Santek, B., Felski, M., Friehs, K., Lotz, M., & Flaschel, E. (2010). Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on potato liquor. ENGINEERING IN LIFE SCIENCES, 10(2), NA. https://doi.org/10.1002/elsc.200900077
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  • [78]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1588919
    Spexard, M., Beshay, U., Risse, J. M., Miksch, G., & Flaschel, E. (2010). Screening for conditions of enhanced production of a recombinant beta-glucanase secreted into the medium by Escherichia coli. BIOTECHNOLOGY LETTERS, 32(2), 243-248. https://doi.org/10.1007/s10529-009-0133-z
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  • [77]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796749
    Flaschel, E. (2010). Biocatalysis - New tasks, new approaches. CHEMIE INGENIEUR TECHNIK, 82(1-2), 3. https://doi.org/10.1002/cite.201090006
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  • [76]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1635287
    Santek, B., Felski, M., Friehs, K., Lotz, M., & Flaschel, E. (2009). Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on a synthetic medium. ENGINEERING IN LIFE SCIENCES, 9(1), 23-28. https://doi.org/10.1002/elsc.200700032
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  • [75]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1591533
    Tschapalda, K., Streitner, N., Voß, C., & Flaschel, E. (2009). Generation of chromosomal DNA during alkaline lysis and removal by reverse micellar extraction. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 84(1), 199-204. https://doi.org/10.1007/s00253-009-2088-3
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  • [74]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636091
    Beshay, U., Miksch, G., Friehs, K., & Flaschel, E. (2009). Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli. BIOPROCESS AND BIOSYSTEMS ENGINEERING, 32(2), 149-158. https://doi.org/10.1007/s00449-008-0227-3
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  • [73]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1634165
    Sommer, B., Friehs, K., Flaschel, E., Reck, M., Stahl, F., & Scheper, T. (2009). Extracellular production and affinity purification of recombinant proteins with Escherichia coli using the versatility of the maltose binding protein. JOURNAL OF BIOTECHNOLOGY, 140(3-4), 194-202. https://doi.org/10.1016/j.jbiotec.2009.01.010
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  • [72]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585399
    Beshay, U., Friehs, K., & Flaschel, E. (2008). Growth of myxamoebae of the cellular slime mold Dictyostelium discoideum in suspension and immobilized form on living bacteria. PROCESS BIOCHEMISTRY, 43(11), 1281-1287. https://doi.org/10.1016/j.procbio.2008.07.009
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  • [71]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585611 OA
    Wei, N., Flaschel, E., Friehs, K., & Nattkemper, T. W. (2008). A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classification. BMC Bioinformatics, 9(1), 449. https://doi.org/10.1186/1471-2105-9-449
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  • [70]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587590 OA
    Vijayendran, C., Barsch, A., Friehs, K., Niehaus, K., Becker, A., & Flaschel, E. (2008). Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling. GENOME BIOLOGY, 9(4), R72. https://doi.org/10.1186/gb-2008-9-4-r72
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  • [69]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587283
    Flaschel, E. (2008). Can we expect a breakthrough in downstream processing of biotechnological products in the near future? Chemical Engineering & Technology, 31(6), 809. https://doi.org/10.1002/ceat.200890024
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  • [68]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587404
    Flaschel, E. (2008). Renovation of biotechnological products - Faces a revolution? CHEMIE INGENIEUR TECHNIK, 80(6), 695. https://doi.org/10.1002/cite.200890044
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  • [67]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587409
    Streitner, N., Voß, C., & Flaschel, E. (2008). Isolation of Plasmid-DNA by inverse micelles two phase system - Optimization of the reverse extraction. CHEMIE INGENIEUR TECHNIK, 80(6), 831-837. https://doi.org/10.1002/cite.200800037
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  • [66]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585617
    Miksch, G., Ryu, S., Risse, J. M., & Flaschel, E. (2008). Factors that influence the extracellular expression of streptavidin in Escherichia coli using a bacteriocin release protein. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 81(2), 319-326. https://doi.org/10.1007/s00253-008-1673-1
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  • [65]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631667 OA
    Vijayendran, C., Burgemeister, S., Friehs, K., Niehaus, K., & Flaschel, E. (2007). 2DBase: 2D-PAGE database of Escherichia coli. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 363(3), 822-827. https://doi.org/10.1016/j.bbrc.2007.09.050
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  • [64]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1594835
    Vijayendran, C., Polen, T., Wendisch, V. F., Friehs, K., Niehaus, K., & Flaschel, E. (2007). The plasticity of global proteome and genome expression analyzed in closely related W3110 and MG1655 strains of a well-studied model organism, Escherichia coli-K12. Journal of Biotechnology, 128(4), 747-761. https://doi.org/10.1016/j.jbiotec.2006.12.026
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  • [63]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1595739
    Wei, N., You, J., Friehs, K., Flaschel, E., & Nattkemper, T. W. (2007). In situ dark field microscopy for on-line monitoring of yeast cultures. BIOTECHNOLOGY LETTERS, 29(3), 373-378. https://doi.org/10.1007/s10529-006-9245-x
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  • [62]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593120
    Wei, N., You, J., Friehs, K., Flaschel, E., & Nattkemper, T. W. (2007). An in situ probe for on-line monitoring of cell density and viability on the basis of dark field microscopy in conjunction with image processing and supervised machine learning. Biotechnology and Bioengineering, 97(6), 1489-1500. https://doi.org/10.1002/bit.21368
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  • [61]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1632656
    Streitner, N., Voß, C., & Flaschel, E. (2007). Reverse micellar extraction systems for the purification of pharmaceutical grade plasmid DNA. JOURNAL OF BIOTECHNOLOGY, 131(2), 188-196. https://doi.org/10.1016/j.jbiotec.2007.06.011
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  • [60]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593482
    Beshay, U., Miksch, G., Friehs, K., & Flaschel, E. (2007). Improved beta-glucanase production by a recombinant Escherichia coli strain using a zinc-ion supplemented medium. ENGINEERING IN LIFE SCIENCES, 7(3), 253-258. https://doi.org/10.1002/elsc.200620191
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  • [59]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593326
    Beshay, U., Miksch, G., & Flaschel, E. (2007). Improvement of a beta-glucanase activity test by taking into account the batch reactor balance of the test system. BIOPROCESS AND BIOSYSTEMS ENGINEERING, 30(4), 251-259. https://doi.org/10.1007/s00449-007-0121-4
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  • [58]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631107
    Blaesen, M., Friehs, K., & Flaschel, E. (2007). Recycling of bacterial biomass in a process of L-threonine production by means of a recombinant strain of Escherichia coli. JOURNAL OF BIOTECHNOLOGY, 132(4), 431-437. https://doi.org/10.1016/j.jbiotec.2007.08.011
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  • [57]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631661
    Beshay, U., Miksch, G., Friehs, K., & Flaschel, E. (2007). Increasing the secretion ability of the kil gene for recombinant proteins in Escherichia coli by using a strong stationary-phase promoter. BIOTECHNOLOGY LETTERS, 29(12), 1893-1901. https://doi.org/10.1007/s10529-007-9477-4
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  • [56]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599823
    Flaschel, E., & Hempel, D. (2006). White biotechnology. CHEMIE INGENIEUR TECHNIK, 78(3), 153. https://doi.org/10.1002/cite.200690010
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  • [55]
    2006 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1599661
    Flaschel, E. (2006). Reactor performance in the presence of catalyst deactivation. Engineering in Life Sciences, ENGINEERING IN LIFE SCIENCES, 6, 131-138. Wiley-VCH. https://doi.org/10.1002/elsc.200620900
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  • [54]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1600329
    Miksch, G., Bettenworth, F., Friehs, K., Flaschel, E., Saalbach, A., & Nattkemper, T. W. (2006). A rapid reporter system using GFP as a reporter protein for identification and screening of synthetic stationary-phase promoters in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 70(2), 229-236. https://doi.org/10.1007/s00253-005-0060-4
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  • [53]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1597472
    Blaesen, M., Flaschel, E., & Friehs, K. (2006). Sustainable production: Recycling of bacterial biomass resulting from a fermentation process with Klebsiella planticola. CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY, 20(3), 263-268.
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  • [52]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599112
    Voß, C., Lindau, D., & Flaschel, E. (2006). Production of recombinant RNase Ba and its application in downstream processing of plasmid DNA for pharmaceutical use. BIOTECHNOLOGY PROGRESS, 22(3), 737-744. https://doi.org/10.1021/bp050417e
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  • [51]
    2005 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2906664
    Polen, T., Wendisch, V. F., Friehs, K., Niehaus, K., Flaschel, E., & Vijayendran, C. (2005). The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli. MOLECULAR & CELLULAR PROTEOMICS, 4(8), S248-S248.
    PUB | WoS
     
  • [50]
    2005 | Monographie | PUB-ID: 2714309
    Bettenworth, F., Miksch, G., Fries, K., Flaschel, E., Saalbach, A., Eickmeyer, J., & Nattkemper, T. W. (2005). An Online Monitoring System for the Screening of Stationary-Phase Promoters in E. Coli using GFP as a Reporter Protein.
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  • [49]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604386
    Arndt, M., Kleist, S., Miksch, G., Friehs, K., Flaschel, E., Trierweiler, J., & Hitzmann, B. (2005). A feedforward-feedback substrate controller based on a Kalman filter for a fed-batch cultivation of Escherichia coli producing phytase. COMPUTERS & CHEMICAL ENGINEERING, 29(5), 1113-1120. https://doi.org/10.1016/j.compchemeng.2004.11.011
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  • [48]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1946602
    Wei, N., Flaschel, E., Saalbach, A., Twellmann, T., & Nattkemper, T. W. (2005). Reagent-free automatic cell viability determination using neural networks based machine vision and dark-field microscopy in Saccharomyces cerevisiae. Conf Proc IEEE Eng Med Biol Soc, 6, 6305-6308. https://doi.org/10.1109/iembs.2005.1615939
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  • [47]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1601074
    Miksch, G., Bettenworth, F., Friehs, K., & Flaschel, E. (2005). The sequence upstream of the -10 consensus sequence modulates the strength and induction time of stationary-phase promoters in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 69(3), 312-320. https://doi.org/10.1007/s00253-005-0016-8
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  • [46]
    2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1601848
    Miksch, G., Bettenworth, F., Friehs, K., Flaschel, E., Saalbach, A., Twellmann, T., & Nattkemper, T. W. (2005). Libraries of synthetic stationary-phase and stress promoters as a tool for fine-tuning of expression of recombinant proteins in Escherichia coli. Journal of Biotechnology, JOURNAL OF BIOTECHNOLOGY, 120, 25-37. ELSEVIER SCIENCE BV. https://doi.org/10.1016/j.jbiotec.2005.04.027
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  • [45]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604877
    Risse, J. M., Pühler, A., & Flaschel, E. (2005). Production of N-acetyl-phosphinothricin: A substance used for inducing male sterility in transgenic plants. ENGINEERING IN LIFE SCIENCES, 5(1), 38-45. https://doi.org/10.1002/elsc.200402078
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  • [44]
    2005 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1601124
    Vijayendran, C., Polen, T., Wendisch, V., Friehs, K., Niehaus, K., & Flaschel, E. (2005). The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli. Molecular & Cellular Proteomics, 4(8: Suppl. 1), S248.
    PUB | WoS
     
  • [43]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608845
    Han, S. I., Friehs, K., & Flaschel, E. (2004). Cultivation of Dictyostelium discoideum on an improved synthetic medium in a conventional bioreactor. PROCESS BIOCHEMISTRY, 39(5), 585-589. https://doi.org/10.1016/S0032-9592(03)00122-5
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  • [42]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1607969
    Han, S. I., Friehs, K., & Flaschel, E. (2004). Improvement of a synthetic medium for Dictyostelium discoideum. PROCESS BIOCHEMISTRY, 39(8), 925-930. https://doi.org/10.1016/S0032-9592(03)00215-2
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  • [41]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609051
    Voß, C., Schmidt, T., Schleef, M., Friehs, K., & Flaschel, E. (2004). Effect of ammonium chloride on plasmid DNA production in high cell density batch culture for biopharmaceutical use. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 79(1), 57-62. https://doi.org/10.1002/jctb.941
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  • [40]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608382
    Lu, Y. H., Knol, J. C., Linskens, M. H. K., Friehs, K., van Haastert, P. J. M., & Flaschel, E. (2004). Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium. JOURNAL OF BIOTECHNOLOGY, 108(3), 243-251. https://doi.org/10.1016/j.biotec.2003.12.006
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  • [39]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606278
    Lu, Y. H., Knol, J. C., Linskens, M. H. K., Friehs, K., van Haastert, P. J. M., & Flaschel, E. (2004). Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 65(5), 547-552. https://doi.org/10.1007/s00253-004-1620-8
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  • [38]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606443
    Lu, Y. H., Beshay, U., Friehs, K., & Flaschel, E. (2004). Mass production of Dictyostelium discoideum in homogenous and hetergeneous cultivation systems. PROCESS BIOCHEMISTRY, 39(12), 1859-1870. https://doi.org/10.1016/j.procbio.2003.09.012
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  • [37]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609437
    Beshay, U., Friehs, K., Azzam, A. E. M., & Flaschel, E. (2003). Analysis of the behaviour of Dictyostelium discoideum in immobilised state by means of continuous cultivation. BIOPROCESS AND BIOSYSTEMS ENGINEERING, 26(2), 117-122. https://doi.org/10.1007/s00449-003-0339-8
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  • [36]
    2003 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1610736
    Schleef, M., Voß, C., Schmidt, T., & Flaschel, E. (2003). Plasmid topology - An important factor influencing the performance of DNA drug delivery. JOURNAL OF LIPOSOME RESEARCH, 13(1), 82-83.
    PUB | WoS
     
  • [35]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1610824
    Beshay, U., Friehs, K., Azzam, A. E. M., & Flaschel, E. (2003). Cultivation of Dictyostelium discoideum in immobilized form by colonization of porous supports. PROCESS BIOCHEMISTRY, 38(11), 1521-1529. https://doi.org/10.1016/S0032-9592(03)00042-6
    PUB | DOI | WoS
     
  • [34]
    2003 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1610932
    Schleef, M., Voß, C., Schmidt, T., & Flaschel, E. (2003). Plasmid vector stability in production, application and storage. JOURNAL OF GENE MEDICINE, 5(3), S26-S26.
    PUB | WoS
     
  • [33]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609656
    Voß, C., Schmidt, T., Schleef, M., Friehs, K., & Flaschel, E. (2003). Production of supercoiled multimeric plasmid DNA for biopharmaceutical application. JOURNAL OF BIOTECHNOLOGY, 105(3), 205-213. https://doi.org/10.1016/j.jbiotec.2003.07.004
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  • [32]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609485
    Stephan, M., Beshay, U., Friehs, K., & Flaschel, E. (2003). Influence of medium composition on growth behaviour of Dictyostelium discoideum for cultivation on axenic media. PROCESS BIOCHEMISTRY, 39(3), 333-343. https://doi.org/10.1016/S0032-9592(03)00085-2
    PUB | DOI | WoS
     
  • [31]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880734
    Schierl, F., Friehs, K., Risse, J. M., & Flaschel, E. (2002). Herstellung von Mediumskomponenten aus mikrobieller Biomasse. Freiberger Forschungshefte, A 866, 112-124.
    PUB
     
  • [30]
    2002 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1613125
    Hettwer, J., Oldenburg, H., & Flaschel, E. (2002). Enzymic routes to dihydroxyacetone phosphate or immediate precursors. Journal of Molecular Catalysis B: Enzymatic, JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 19, 215-222. ELSEVIER SCIENCE BV. https://doi.org/10.1016/S1381-1177(02)00170-4
    PUB | DOI | WoS
     
  • [29]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613472
    Miksch, G., Kleist, S., Friehs, K., & Flaschel, E. (2002). Overexpression of the phytase from Escherichia coli and its extracellular production in bioreactors. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 59(6), 685-694. https://doi.org/10.1007/s00253-002-1071-z
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [28]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880242
    Risse, J. M., Friehs, K., & Flaschel, E. (2001). Recycling of Biomass Resulting from Fermentation Processes with Bacillus licheniformis. Chem. Eng. Technol., 24(10), 141-145.
    PUB
     
  • [27]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616886
    Schroter, K., Flaschel, E., Pühler, A., & Becker, A. (2001). Xanthomonas campestris pv. campestris secretes the endoglucanases ENGXCA and ENGXCB: construction of an endoglucanase-deficient mutant for industrial xanthan production. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 55(6), 727-733. https://doi.org/10.1007/s002530100654
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [26]
    2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1880243
    Miksch, G., & Flaschel, E. (2001). Secretion of homologous and heterologous recombinant proteins in Escherichia coli and other gram-negative bacteria by using a new secretion system. In O. - W. Merten, D. Mattanovich, & C. Lang (Eds.), Recombinant protein production with prokaryotic and eukaryotic cells - A comparative view on host physiology. Selected articles from the meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th-8th October 2000 (pp. 347-358). Dordrecht: Kluwer Academic Publishers.
    PUB
     
  • [25]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619389
    Risse, J. M., Friehs, K., & Flaschel, E. (2000). Biomasserückführung am Beispiel Bacillus licheniformis. CHEMIE INGENIEUR TECHNIK, 72(7), 750-754. https://doi.org/10.1002/1522-2640(200007)72:7<750::AID-CITE750>3.0.CO;2-7
    PUB | DOI | WoS
     
  • [24]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621141
    Baier, R., Schiene, K., Kohring, B., Flaschel, E., & Niehaus, K. (1999). Alfalfa and tobacco cells react differently to chitin oligosaccharides and Sinorhizobium meliloti nodulation factors. PLANTA, 210(1), 157-164. https://doi.org/10.1007/s004250050665
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [23]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621612
    Schmidt, T., Friehs, K., Schleef, M., Voß, C., & Flaschel, E. (1999). Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis. ANALYTICAL BIOCHEMISTRY, 274(2), 235-240. https://doi.org/10.1006/abio.1999.4291
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [22]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622862
    Miksch, G., Neitzel, R., Friehs, K., & Flaschel, E. (1999). High-level expression of a recombinant protein in Klebsiella planticola owing to induced secretion into the culture medium. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 51(5), 627-632. https://doi.org/10.1007/s002530051442
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [21]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1625697
    Friehs, K., Schierl, F., & Flaschel, E. (1998). Reprocessing of bacterial biomass for recycling as a medium component in fermentation processes. CHEMIE INGENIEUR TECHNIK, 70(4), 435-437. https://doi.org/10.1002/cite.330700416
    PUB | DOI | WoS
     
  • [20]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626311
    Margot, A., Flaschel, E., & Renken, A. (1998). Development of a continuously operated reactor for the limited hydrolysis of whey protein by trypsin. PROCESS BIOCHEMISTRY, 33(2), 125-131. https://doi.org/10.1016/S0032-9592(97)00038-1
    PUB | DOI | WoS
     
  • [19]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626283
    Huneke, F. U., & Flaschel, E. (1998). Behaviour of liquid/liquid/solid three-phase fixed bed reactors with application in biocatalysis. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 71(3), 213-222. https://doi.org/10.1002/(SICI)1097-4660(199803)71:3<213::AID-JCTB850>3.3.CO;2-A
    PUB | DOI | WoS
     
  • [18]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1637759
    Miksch, G., Neitzel, R., Fiedler, E., Friehs, K., & Flaschel, E. (1997). Extracellular production of a hybrid beta-glucanase from Bacillus by Escherichia coli under different cultivation conditions in shaking cultures and bioreactors. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 47(2), 120-126. https://doi.org/10.1007/s002530050899
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [17]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636857
    Miksch, G., Fiedler, E., Dobrowolski, P., & Flaschel, E. (1997). Controlled secretion into the culture medium of a hybrid beta-glucanase by Acetobacter methanolicus mediated by the kil gene of Escherichia coli located on a Tn5-derived transposon. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 47(5), 530-536. https://doi.org/10.1007/s002530050968
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [16]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628040
    Margot, A., Flaschel, E., & Renken, A. (1997). Empirical kinetic models for tryptic whey-protein hydrolysis. PROCESS BIOCHEMISTRY, 32(3), 217-223. https://doi.org/10.1016/S0032-9592(96)00060-X
    PUB | DOI | WoS
     
  • [15]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626566
    Kohring, B., Baier, R., Niehaus, K., Pühler, A., & Flaschel, E. (1997). Production of nodulation factors by Rhizobium meliloti: fermentation, purification and characterization of glycolipids. GLYCOCONJUGATE JOURNAL, 14(8), 963-971. https://doi.org/10.1023/A:1018575013101
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [14]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627108
    Poppenborg, L., Friehs, K., & Flaschel, E. (1997). The green fluorescent protein is a versatile reporter for bioprocess monitoring. JOURNAL OF BIOTECHNOLOGY, 58(2), 79-88. https://doi.org/10.1016/S0168-1656(97)00134-X
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [13]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1638581
    Hentsch, M., Warnery, P., Renken, A., & Flaschel, E. (1996). Study of the simultaneous partitioning of proteins and surfactant in reverse micellar two-phase systems - Potential impact upon purification efficiency. BIOSEPARATION, 6(2), 67-76.
    PUB | WoS
     
  • [12]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628395
    Schmidt, T., Friehs, K., & Flaschel, E. (1996). Rapid determination of plasmid copy number. JOURNAL OF BIOTECHNOLOGY, 49(1-3), 219-229. https://doi.org/10.1016/0168-1656(96)01519-2
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [11]
    1996 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1639656
    Schmidt, T., Friehs, K., & Flaschel, E. (1996). Plasmid copy number as a process variable for fermentation control. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 211, 191-BIOT.
    PUB | WoS
     
  • [10]
    1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641313
    Flaschel, E., Margot, A., Dohmen, M., & Renken, A. (1995). Conversion-Space Time Profiles of Stirred-Tank Reactors Continuously Fed with Reactants and Catalyst under Conditions of Strong Catalyst Deactivation. Chemical Engineering Science, 50(7), 1143-1147. https://doi.org/10.1016/0009-2509(94)00491-9
    PUB | DOI | WoS
     
  • [9]
    1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641188
    HENTSCH, M., Flaschel, E., & RENKEN, A. (1995). RADIOLABELED AOT FOR STUDIES OF THE PARTITIONING OF THE SURFACTANT DURING PROTEIN EXTRACTION BY MEANS OF REVERSE MICELLAR 2-PHASE SYSTEMS. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES, 191(1), 201-208. https://doi.org/10.1007/BF02035998
    PUB | DOI | WoS
     
  • [8]
    1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1644182
    MARGOT, A., Flaschel, E., & RENKEN, A. (1994). CONTINUOUS MONITORING OF ENZYMATIC WHEY-PROTEIN HYDROLYSIS - CORRELATION OF BASE CONSUMPTION WITH SOLUBLE NITROGEN-CONTENT. PROCESS BIOCHEMISTRY, 29(4), 257-262. https://doi.org/10.1016/0032-9592(94)80066-9
    PUB | DOI | WoS
     
  • [7]
    1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641804
    HUNEKE, F. U., & Flaschel, E. (1994). PHASE DISTRIBUTION IN LIQUID-LIQUID 3-PHASE FIXED-BED REACTORS. CHEMIE INGENIEUR TECHNIK, 66(12), 1649-1651. https://doi.org/10.1002/cite.330661215
    PUB | DOI | WoS
     
  • [6]
    1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1643205
    Flaschel, E., & SCHAFFER, T. (1994). NEW EVIDENCE FOR DIMERIZATION-DEPENDENCE OF THE ACTIVITY OF CANDIDA-RUGOSA LIPASE. Biocatalysis, BIOCATALYSIS, 9, 241-248. HARWOOD ACAD PUBL GMBH. https://doi.org/10.3109/10242429408992123
    PUB | DOI | WoS
     
  • [5]
    1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1643820
    POPPENBORG, L., & Flaschel, E. (1994). AFFINITY EXTRACTION OF PROTEINS BY MEANS OF REVERSE MICELLAR PHASES CONTAINING A METAL-CHELATING SURFACTANT. BIOTECHNOLOGY TECHNIQUES, 8(5), 307-312. https://doi.org/10.1007/BF02428972
    PUB | DOI | WoS
     
  • [4]
    1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1646173 OA
    Flaschel, E., & Friehs, K. (1993). Improvement of downstream processing of recombinant proteins by means of genetic engineering. Biotechnology Advances, 11(1), 31-77. https://doi.org/10.1016/0734-9750(93)90409-G
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [3]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629782
    Hentsch, M., Menoud, P., Flaschel, E., & Renken, A. (1992). The effect of temperature on the kinetics of a reverse micellar protein extraction process. BIOTECHNOLOGY TECHNIQUES, 6(5), 423-428.
    PUB | WoS
     
  • [2]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629787
    Hentsch, M., Menoud, P., Steiner, L., Flaschel, E., & Renken, A. (1992). Optimization of the surfactant (AOT) concentration in a reverse micellar extraction process. BIOTECHNOLOGY TECHNIQUES, 6(4), 359-364. https://doi.org/10.1007/BF02439326
    PUB | DOI | WoS
     
  • [1]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1647759
    MARGOT, A., RICHOZ, C., Flaschel, E., & RENKEN, A. (1992). INFLUENCE OF TRYPSIN DEACTIVATION ON THE HYDROLYSIS OF WHEY PROTEINS. CHEMIE INGENIEUR TECHNIK, 64(6), 551-553. https://doi.org/10.1002/cite.330640616
    PUB | DOI | WoS
     

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