Erwin Flaschel
PEVZ-ID
93 Publikationen
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904075Müller J, Risse JM, Jussen D, Flaschel E. Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies (vol 163, pg 325, 2013). JOURNAL OF BIOTECHNOLOGY. 2016;226:76-77.PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906183Schulte F, Flaschel E, Niehaus K. Proteome-Based Analysis of Colloidal Instability Enables the Detection of Haze-Active Proteins in Beer. Journal of Agricultural and Food Chemistry. 2016;64(35):6752-6761.PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903023Wetzel D, Müller J, Flaschel E, Friehs K, Risse JM. Fed-batch production and secretion of streptavidin by Hansenula polymorpha: Evaluation of genetic factors and bioprocess development. JOURNAL OF BIOTECHNOLOGY. 2016;225:3-9.PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906197Müller J, Bruhn S, Flaschel E, Friehs K, Risse JM. GAP promoter-based fed-batch production of highly bioactive core streptavidin by Pichia pastoris. BIOTECHNOLOGY PROGRESS. 2016;32(4):855-864.PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2900637Müller J, Wetzel D, Flaschel E, Friehs K, Risse JM. Constitutive production and efficient secretion of soluble full-length streptavidin by an Escherichia coli 'leaky mutant'. Journal of Biotechnology. 2016;221:91-100.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759080Grimm P, Risse JM, Müller J, et al. Applicability of Euglena gracilis for biorefineries demonstrated by the production of α-tocopherol and paramylon followed by anaerobic digestion. Journal of Biotechnology. 2015;215:72-79.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2679910Selvamani RSV, Telaar M, Friehs K, Flaschel E. Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA). Microbial Cell Factories. 2014;13(1): 58.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2675672Selvamani RSV, Friehs K, Flaschel E. Extracellular recombinant protein production under continuous culture conditions with Escherichia coli using an alternative plasmid selection mechanism. Bioprocess and Biosystems Engineering. 2014;37(3):401-413.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2551139Müller JM, Risse JM, Jussen D, Flaschel E. Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies. Journal of Biotechnology. 2013;163(3):325-332.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945165Vijayendran C, Flaschel E. Impact of profiling technologies in the understanding of recombinant protein production. Adv Biochem Eng Biotechnol. 2010;121:45-70.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1929340Burgemeister S, Nattkemper TW, Noll T, Hoffrogge R, Flaschel E. CellViCAM-Cell viability classification for animal cell cultures using dark field micrographs. JOURNAL OF BIOTECHNOLOGY. 2010;149(4):310-316.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796536Sommer B, Friehs K, Flaschel E. Efficient production of extracellular proteins with Escherichia coli by means of optimized coexpression of bacteriocin release proteins. JOURNAL OF BIOTECHNOLOGY. 2010;145(4):350-358.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1588919Spexard M, Beshay U, Risse JM, Miksch G, Flaschel E. Screening for conditions of enhanced production of a recombinant beta-glucanase secreted into the medium by Escherichia coli. BIOTECHNOLOGY LETTERS. 2010;32(2):243-248.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1591533Tschapalda K, Streitner N, Voß C, Flaschel E. Generation of chromosomal DNA during alkaline lysis and removal by reverse micellar extraction. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2009;84(1):199-204.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636091Beshay U, Miksch G, Friehs K, Flaschel E. Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 2009;32(2):149-158.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1634165Sommer B, Friehs K, Flaschel E, Reck M, Stahl F, Scheper T. Extracellular production and affinity purification of recombinant proteins with Escherichia coli using the versatility of the maltose binding protein. JOURNAL OF BIOTECHNOLOGY. 2009;140(3-4):194-202.PUB | DOI | WoS | PubMed | Europe PMC
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585611Wei N, Flaschel E, Friehs K, Nattkemper TW. A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classification. BMC Bioinformatics. 2008;9(1):449.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587590Vijayendran C, Barsch A, Friehs K, Niehaus K, Becker A, Flaschel E. Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling. GENOME BIOLOGY. 2008;9(4):R72.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585617Miksch G, Ryu S, Risse JM, Flaschel E. Factors that influence the extracellular expression of streptavidin in Escherichia coli using a bacteriocin release protein. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2008;81(2):319-326.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1594835Vijayendran C, Polen T, Wendisch VF, Friehs K, Niehaus K, Flaschel E. The plasticity of global proteome and genome expression analyzed in closely related W3110 and MG1655 strains of a well-studied model organism, Escherichia coli-K12. Journal of Biotechnology. 2007;128(4):747-761.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1595739Wei N, You J, Friehs K, Flaschel E, Nattkemper TW. In situ dark field microscopy for on-line monitoring of yeast cultures. BIOTECHNOLOGY LETTERS. 2007;29(3):373-378.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593120Wei N, You J, Friehs K, Flaschel E, Nattkemper TW. An in situ probe for on-line monitoring of cell density and viability on the basis of dark field microscopy in conjunction with image processing and supervised machine learning. Biotechnology and Bioengineering. 2007;97(6):1489-1500.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1632656Streitner N, Voß C, Flaschel E. Reverse micellar extraction systems for the purification of pharmaceutical grade plasmid DNA. JOURNAL OF BIOTECHNOLOGY. 2007;131(2):188-196.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593326Beshay U, Miksch G, Flaschel E. Improvement of a beta-glucanase activity test by taking into account the batch reactor balance of the test system. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 2007;30(4):251-259.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631107Blaesen M, Friehs K, Flaschel E. Recycling of bacterial biomass in a process of L-threonine production by means of a recombinant strain of Escherichia coli. JOURNAL OF BIOTECHNOLOGY. 2007;132(4):431-437.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631661Beshay U, Miksch G, Friehs K, Flaschel E. Increasing the secretion ability of the kil gene for recombinant proteins in Escherichia coli by using a strong stationary-phase promoter. BIOTECHNOLOGY LETTERS. 2007;29(12):1893-1901.PUB | DOI | WoS | PubMed | Europe PMC
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1600329Miksch G, Bettenworth F, Friehs K, Flaschel E, Saalbach A, Nattkemper TW. A rapid reporter system using GFP as a reporter protein for identification and screening of synthetic stationary-phase promoters in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2006;70(2):229-236.PUB | DOI | WoS | PubMed | Europe PMC
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599112Voß C, Lindau D, Flaschel E. Production of recombinant RNase Ba and its application in downstream processing of plasmid DNA for pharmaceutical use. BIOTECHNOLOGY PROGRESS. 2006;22(3):737-744.PUB | DOI | WoS | PubMed | Europe PMC
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2005 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2906664Polen T, Wendisch VF, Friehs K, Niehaus K, Flaschel E, Vijayendran C. The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli. MOLECULAR & CELLULAR PROTEOMICS. 2005;4(8):S248-S248.PUB | WoS
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2005 | Monographie | PUB-ID: 2714309Bettenworth F, Miksch G, Fries K, et al. An Online Monitoring System for the Screening of Stationary-Phase Promoters in E. Coli using GFP as a Reporter Protein.; 2005.PUB
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604386Arndt M, Kleist S, Miksch G, et al. A feedforward-feedback substrate controller based on a Kalman filter for a fed-batch cultivation of Escherichia coli producing phytase. COMPUTERS & CHEMICAL ENGINEERING. 2005;29(5):1113-1120.PUB | DOI | WoS
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1946602Wei N, Flaschel E, Saalbach A, Twellmann T, Nattkemper TW. Reagent-free automatic cell viability determination using neural networks based machine vision and dark-field microscopy in Saccharomyces cerevisiae. Conf Proc IEEE Eng Med Biol Soc. 2005;6:6305-6308.PUB | DOI | PubMed | Europe PMC
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1601074Miksch G, Bettenworth F, Friehs K, Flaschel E. The sequence upstream of the -10 consensus sequence modulates the strength and induction time of stationary-phase promoters in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2005;69(3):312-320.PUB | DOI | WoS | PubMed | Europe PMC
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2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1601848Miksch G, Bettenworth F, Friehs K, et al. Libraries of synthetic stationary-phase and stress promoters as a tool for fine-tuning of expression of recombinant proteins in Escherichia coli. In: Journal of Biotechnology. JOURNAL OF BIOTECHNOLOGY. Vol 120. ELSEVIER SCIENCE BV; 2005: 25-37.PUB | DOI | WoS | PubMed | Europe PMC
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2005 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1601124Vijayendran C, Polen T, Wendisch V, Friehs K, Niehaus K, Flaschel E. The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli. Molecular & Cellular Proteomics. 2005;4(8: Suppl. 1):S248.PUB | WoS
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609051Voß C, Schmidt T, Schleef M, Friehs K, Flaschel E. Effect of ammonium chloride on plasmid DNA production in high cell density batch culture for biopharmaceutical use. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. 2004;79(1):57-62.PUB | DOI | WoS
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608382Lu YH, Knol JC, Linskens MHK, Friehs K, van Haastert PJM, Flaschel E. Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium. JOURNAL OF BIOTECHNOLOGY. 2004;108(3):243-251.PUB | DOI | WoS | PubMed | Europe PMC
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606278Lu YH, Knol JC, Linskens MHK, Friehs K, van Haastert PJM, Flaschel E. Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2004;65(5):547-552.PUB | DOI | WoS | PubMed | Europe PMC
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609437Beshay U, Friehs K, Azzam AEM, Flaschel E. Analysis of the behaviour of Dictyostelium discoideum in immobilised state by means of continuous cultivation. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 2003;26(2):117-122.PUB | DOI | WoS | PubMed | Europe PMC
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609656Voß C, Schmidt T, Schleef M, Friehs K, Flaschel E. Production of supercoiled multimeric plasmid DNA for biopharmaceutical application. JOURNAL OF BIOTECHNOLOGY. 2003;105(3):205-213.PUB | DOI | WoS | PubMed | Europe PMC
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880734Schierl F, Friehs K, Risse JM, Flaschel E. Herstellung von Mediumskomponenten aus mikrobieller Biomasse. Freiberger Forschungshefte. 2002;A 866:112-124.PUB
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2002 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1613125Hettwer J, Oldenburg H, Flaschel E. Enzymic routes to dihydroxyacetone phosphate or immediate precursors. In: Journal of Molecular Catalysis B: Enzymatic. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC. Vol 19. ELSEVIER SCIENCE BV; 2002: 215-222.PUB | DOI | WoS
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613472Miksch G, Kleist S, Friehs K, Flaschel E. Overexpression of the phytase from Escherichia coli and its extracellular production in bioreactors. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2002;59(6):685-694.PUB | DOI | WoS | PubMed | Europe PMC
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880242Risse JM, Friehs K, Flaschel E. Recycling of Biomass Resulting from Fermentation Processes with Bacillus licheniformis. Chem. Eng. Technol. 2001;24(10):141-145.PUB
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616886Schroter K, Flaschel E, Pühler A, Becker A. Xanthomonas campestris pv. campestris secretes the endoglucanases ENGXCA and ENGXCB: construction of an endoglucanase-deficient mutant for industrial xanthan production. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2001;55(6):727-733.PUB | DOI | WoS | PubMed | Europe PMC
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2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1880243Miksch G, Flaschel E. Secretion of homologous and heterologous recombinant proteins in Escherichia coli and other gram-negative bacteria by using a new secretion system. In: Merten O-W, Mattanovich D, Lang C, eds. Recombinant protein production with prokaryotic and eukaryotic cells - A comparative view on host physiology. Selected articles from the meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th-8th October 2000. Dordrecht: Kluwer Academic Publishers; 2001: 347-358.PUB
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1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621141Baier R, Schiene K, Kohring B, Flaschel E, Niehaus K. Alfalfa and tobacco cells react differently to chitin oligosaccharides and Sinorhizobium meliloti nodulation factors. PLANTA. 1999;210(1):157-164.PUB | DOI | WoS | PubMed | Europe PMC
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1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621612Schmidt T, Friehs K, Schleef M, Voß C, Flaschel E. Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis. ANALYTICAL BIOCHEMISTRY. 1999;274(2):235-240.PUB | DOI | WoS | PubMed | Europe PMC
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1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622862Miksch G, Neitzel R, Friehs K, Flaschel E. High-level expression of a recombinant protein in Klebsiella planticola owing to induced secretion into the culture medium. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 1999;51(5):627-632.PUB | DOI | WoS | PubMed | Europe PMC
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1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1637759Miksch G, Neitzel R, Fiedler E, Friehs K, Flaschel E. Extracellular production of a hybrid beta-glucanase from Bacillus by Escherichia coli under different cultivation conditions in shaking cultures and bioreactors. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 1997;47(2):120-126.PUB | DOI | WoS | PubMed | Europe PMC
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1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636857Miksch G, Fiedler E, Dobrowolski P, Flaschel E. Controlled secretion into the culture medium of a hybrid beta-glucanase by Acetobacter methanolicus mediated by the kil gene of Escherichia coli located on a Tn5-derived transposon. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 1997;47(5):530-536.PUB | DOI | WoS | PubMed | Europe PMC
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1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626566Kohring B, Baier R, Niehaus K, Pühler A, Flaschel E. Production of nodulation factors by Rhizobium meliloti: fermentation, purification and characterization of glycolipids. GLYCOCONJUGATE JOURNAL. 1997;14(8):963-971.PUB | DOI | WoS | PubMed | Europe PMC
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1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627108Poppenborg L, Friehs K, Flaschel E. The green fluorescent protein is a versatile reporter for bioprocess monitoring. JOURNAL OF BIOTECHNOLOGY. 1997;58(2):79-88.PUB | DOI | WoS | PubMed | Europe PMC
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1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1638581Hentsch M, Warnery P, Renken A, Flaschel E. Study of the simultaneous partitioning of proteins and surfactant in reverse micellar two-phase systems - Potential impact upon purification efficiency. BIOSEPARATION. 1996;6(2):67-76.PUB | WoS
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1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628395Schmidt T, Friehs K, Flaschel E. Rapid determination of plasmid copy number. JOURNAL OF BIOTECHNOLOGY. 1996;49(1-3):219-229.PUB | DOI | WoS | PubMed | Europe PMC
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1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641313Flaschel E, Margot A, Dohmen M, Renken A. Conversion-Space Time Profiles of Stirred-Tank Reactors Continuously Fed with Reactants and Catalyst under Conditions of Strong Catalyst Deactivation. Chemical Engineering Science. 1995;50(7):1143-1147.PUB | DOI | WoS
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1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641188HENTSCH M, Flaschel E, RENKEN A. RADIOLABELED AOT FOR STUDIES OF THE PARTITIONING OF THE SURFACTANT DURING PROTEIN EXTRACTION BY MEANS OF REVERSE MICELLAR 2-PHASE SYSTEMS. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES. 1995;191(1):201-208.PUB | DOI | WoS
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