93 Publikationen

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  • [93]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904075
    Müller J, Risse JM, Jussen D, Flaschel E. Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies (vol 163, pg 325, 2013). JOURNAL OF BIOTECHNOLOGY. 2016;226:76-77.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [92]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906183
    Schulte F, Flaschel E, Niehaus K. Proteome-Based Analysis of Colloidal Instability Enables the Detection of Haze-Active Proteins in Beer. Journal of Agricultural and Food Chemistry. 2016;64(35):6752-6761.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [91]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903023
    Wetzel D, Müller J, Flaschel E, Friehs K, Risse JM. Fed-batch production and secretion of streptavidin by Hansenula polymorpha: Evaluation of genetic factors and bioprocess development. JOURNAL OF BIOTECHNOLOGY. 2016;225:3-9.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [90]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906197
    Müller J, Bruhn S, Flaschel E, Friehs K, Risse JM. GAP promoter-based fed-batch production of highly bioactive core streptavidin by Pichia pastoris. BIOTECHNOLOGY PROGRESS. 2016;32(4):855-864.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [89]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2900637
    Müller J, Wetzel D, Flaschel E, Friehs K, Risse JM. Constitutive production and efficient secretion of soluble full-length streptavidin by an Escherichia coli 'leaky mutant'. Journal of Biotechnology. 2016;221:91-100.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [88]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2767378
    Müller J, Risse JM, Friehs K, Flaschel E. Model-based development of an assay for the rapid detection of biotin-blocked binding sites of streptavidin. Engineering in Life Sciences. 2015;15(6):627-639.
    PUB | DOI | WoS
     
  • [87]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759080
    Grimm P, Risse JM, Müller J, et al. Applicability of Euglena gracilis for biorefineries demonstrated by the production of α-tocopherol and paramylon followed by anaerobic digestion. Journal of Biotechnology. 2015;215:72-79.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [86]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2722001
    Schwarzhans JP, Cholewa D, Grimm P, et al. Dependency of the fatty acid composition of Euglena gracilis on growth phase and culture conditions. Journal of Applied Phycology. 2015;27(4):1389-1399.
    PUB | DOI | WoS
     
  • [85]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2679910 OA
    Selvamani RSV, Telaar M, Friehs K, Flaschel E. Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA). Microbial Cell Factories. 2014;13(1): 58.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [84]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2675672
    Selvamani RSV, Friehs K, Flaschel E. Extracellular recombinant protein production under continuous culture conditions with Escherichia coli using an alternative plasmid selection mechanism. Bioprocess and Biosystems Engineering. 2014;37(3):401-413.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [83]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2551139
    Müller JM, Risse JM, Jussen D, Flaschel E. Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies. Journal of Biotechnology. 2013;163(3):325-332.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [82]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945165
    Vijayendran C, Flaschel E. Impact of profiling technologies in the understanding of recombinant protein production. Adv Biochem Eng Biotechnol. 2010;121:45-70.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [81]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1929340
    Burgemeister S, Nattkemper TW, Noll T, Hoffrogge R, Flaschel E. CellViCAM-Cell viability classification for animal cell cultures using dark field micrographs. JOURNAL OF BIOTECHNOLOGY. 2010;149(4):310-316.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [80]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796536
    Sommer B, Friehs K, Flaschel E. Efficient production of extracellular proteins with Escherichia coli by means of optimized coexpression of bacteriocin release proteins. JOURNAL OF BIOTECHNOLOGY. 2010;145(4):350-358.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [79]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1795042
    Santek B, Felski M, Friehs K, Lotz M, Flaschel E. Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on potato liquor. ENGINEERING IN LIFE SCIENCES. 2010;10(2):NA.
    PUB | DOI | WoS
     
  • [78]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1588919
    Spexard M, Beshay U, Risse JM, Miksch G, Flaschel E. Screening for conditions of enhanced production of a recombinant beta-glucanase secreted into the medium by Escherichia coli. BIOTECHNOLOGY LETTERS. 2010;32(2):243-248.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [77]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796749
    Flaschel E. Biocatalysis - New tasks, new approaches. CHEMIE INGENIEUR TECHNIK. 2010;82(1-2):3.
    PUB | DOI | WoS
     
  • [76]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1635287
    Santek B, Felski M, Friehs K, Lotz M, Flaschel E. Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on a synthetic medium. ENGINEERING IN LIFE SCIENCES. 2009;9(1):23-28.
    PUB | DOI | WoS
     
  • [75]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1591533
    Tschapalda K, Streitner N, Voß C, Flaschel E. Generation of chromosomal DNA during alkaline lysis and removal by reverse micellar extraction. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2009;84(1):199-204.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [74]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636091
    Beshay U, Miksch G, Friehs K, Flaschel E. Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 2009;32(2):149-158.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [73]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1634165
    Sommer B, Friehs K, Flaschel E, Reck M, Stahl F, Scheper T. Extracellular production and affinity purification of recombinant proteins with Escherichia coli using the versatility of the maltose binding protein. JOURNAL OF BIOTECHNOLOGY. 2009;140(3-4):194-202.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [72]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585399
    Beshay U, Friehs K, Flaschel E. Growth of myxamoebae of the cellular slime mold Dictyostelium discoideum in suspension and immobilized form on living bacteria. PROCESS BIOCHEMISTRY. 2008;43(11):1281-1287.
    PUB | DOI | WoS
     
  • [71]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585611 OA
    Wei N, Flaschel E, Friehs K, Nattkemper TW. A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classification. BMC Bioinformatics. 2008;9(1):449.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [70]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587590 OA
    Vijayendran C, Barsch A, Friehs K, Niehaus K, Becker A, Flaschel E. Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling. GENOME BIOLOGY. 2008;9(4):R72.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [69]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587283
    Flaschel E. Can we expect a breakthrough in downstream processing of biotechnological products in the near future? Chemical Engineering & Technology. 2008;31(6):809.
    PUB | DOI | WoS
     
  • [68]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587404
    Flaschel E. Renovation of biotechnological products - Faces a revolution? CHEMIE INGENIEUR TECHNIK. 2008;80(6):695.
    PUB | DOI | WoS
     
  • [67]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587409
    Streitner N, Voß C, Flaschel E. Isolation of Plasmid-DNA by inverse micelles two phase system - Optimization of the reverse extraction. CHEMIE INGENIEUR TECHNIK. 2008;80(6):831-837.
    PUB | DOI | WoS
     
  • [66]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585617
    Miksch G, Ryu S, Risse JM, Flaschel E. Factors that influence the extracellular expression of streptavidin in Escherichia coli using a bacteriocin release protein. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2008;81(2):319-326.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [65]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631667 OA
    Vijayendran C, Burgemeister S, Friehs K, Niehaus K, Flaschel E. 2DBase: 2D-PAGE database of Escherichia coli. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007;363(3):822-827.
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  • [64]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1594835
    Vijayendran C, Polen T, Wendisch VF, Friehs K, Niehaus K, Flaschel E. The plasticity of global proteome and genome expression analyzed in closely related W3110 and MG1655 strains of a well-studied model organism, Escherichia coli-K12. Journal of Biotechnology. 2007;128(4):747-761.
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  • [63]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1595739
    Wei N, You J, Friehs K, Flaschel E, Nattkemper TW. In situ dark field microscopy for on-line monitoring of yeast cultures. BIOTECHNOLOGY LETTERS. 2007;29(3):373-378.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [62]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593120
    Wei N, You J, Friehs K, Flaschel E, Nattkemper TW. An in situ probe for on-line monitoring of cell density and viability on the basis of dark field microscopy in conjunction with image processing and supervised machine learning. Biotechnology and Bioengineering. 2007;97(6):1489-1500.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [61]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1632656
    Streitner N, Voß C, Flaschel E. Reverse micellar extraction systems for the purification of pharmaceutical grade plasmid DNA. JOURNAL OF BIOTECHNOLOGY. 2007;131(2):188-196.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [60]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593482
    Beshay U, Miksch G, Friehs K, Flaschel E. Improved beta-glucanase production by a recombinant Escherichia coli strain using a zinc-ion supplemented medium. ENGINEERING IN LIFE SCIENCES. 2007;7(3):253-258.
    PUB | DOI | WoS
     
  • [59]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593326
    Beshay U, Miksch G, Flaschel E. Improvement of a beta-glucanase activity test by taking into account the batch reactor balance of the test system. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 2007;30(4):251-259.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [58]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631107
    Blaesen M, Friehs K, Flaschel E. Recycling of bacterial biomass in a process of L-threonine production by means of a recombinant strain of Escherichia coli. JOURNAL OF BIOTECHNOLOGY. 2007;132(4):431-437.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [57]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631661
    Beshay U, Miksch G, Friehs K, Flaschel E. Increasing the secretion ability of the kil gene for recombinant proteins in Escherichia coli by using a strong stationary-phase promoter. BIOTECHNOLOGY LETTERS. 2007;29(12):1893-1901.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [56]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599823
    Flaschel E, Hempel D. White biotechnology. CHEMIE INGENIEUR TECHNIK. 2006;78(3):153.
    PUB | DOI | WoS
     
  • [55]
    2006 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1599661
    Flaschel E. Reactor performance in the presence of catalyst deactivation. In: Engineering in Life Sciences. ENGINEERING IN LIFE SCIENCES. Vol 6. Wiley-VCH; 2006: 131-138.
    PUB | DOI | WoS
     
  • [54]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1600329
    Miksch G, Bettenworth F, Friehs K, Flaschel E, Saalbach A, Nattkemper TW. A rapid reporter system using GFP as a reporter protein for identification and screening of synthetic stationary-phase promoters in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2006;70(2):229-236.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [53]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1597472
    Blaesen M, Flaschel E, Friehs K. Sustainable production: Recycling of bacterial biomass resulting from a fermentation process with Klebsiella planticola. CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY. 2006;20(3):263-268.
    PUB | WoS
     
  • [52]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599112
    Voß C, Lindau D, Flaschel E. Production of recombinant RNase Ba and its application in downstream processing of plasmid DNA for pharmaceutical use. BIOTECHNOLOGY PROGRESS. 2006;22(3):737-744.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [51]
    2005 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2906664
    Polen T, Wendisch VF, Friehs K, Niehaus K, Flaschel E, Vijayendran C. The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli. MOLECULAR & CELLULAR PROTEOMICS. 2005;4(8):S248-S248.
    PUB | WoS
     
  • [50]
    2005 | Monographie | PUB-ID: 2714309
    Bettenworth F, Miksch G, Fries K, et al. An Online Monitoring System for the Screening of Stationary-Phase Promoters in E. Coli using GFP as a Reporter Protein.; 2005.
    PUB
     
  • [49]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604386
    Arndt M, Kleist S, Miksch G, et al. A feedforward-feedback substrate controller based on a Kalman filter for a fed-batch cultivation of Escherichia coli producing phytase. COMPUTERS & CHEMICAL ENGINEERING. 2005;29(5):1113-1120.
    PUB | DOI | WoS
     
  • [48]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1946602
    Wei N, Flaschel E, Saalbach A, Twellmann T, Nattkemper TW. Reagent-free automatic cell viability determination using neural networks based machine vision and dark-field microscopy in Saccharomyces cerevisiae. Conf Proc IEEE Eng Med Biol Soc. 2005;6:6305-6308.
    PUB | DOI | PubMed | Europe PMC
     
  • [47]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1601074
    Miksch G, Bettenworth F, Friehs K, Flaschel E. The sequence upstream of the -10 consensus sequence modulates the strength and induction time of stationary-phase promoters in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2005;69(3):312-320.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [46]
    2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1601848
    Miksch G, Bettenworth F, Friehs K, et al. Libraries of synthetic stationary-phase and stress promoters as a tool for fine-tuning of expression of recombinant proteins in Escherichia coli. In: Journal of Biotechnology. JOURNAL OF BIOTECHNOLOGY. Vol 120. ELSEVIER SCIENCE BV; 2005: 25-37.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [45]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604877
    Risse JM, Pühler A, Flaschel E. Production of N-acetyl-phosphinothricin: A substance used for inducing male sterility in transgenic plants. ENGINEERING IN LIFE SCIENCES. 2005;5(1):38-45.
    PUB | DOI | WoS
     
  • [44]
    2005 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1601124
    Vijayendran C, Polen T, Wendisch V, Friehs K, Niehaus K, Flaschel E. The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli. Molecular & Cellular Proteomics. 2005;4(8: Suppl. 1):S248.
    PUB | WoS
     
  • [43]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608845
    Han SI, Friehs K, Flaschel E. Cultivation of Dictyostelium discoideum on an improved synthetic medium in a conventional bioreactor. PROCESS BIOCHEMISTRY. 2004;39(5):585-589.
    PUB | DOI | WoS
     
  • [42]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1607969
    Han SI, Friehs K, Flaschel E. Improvement of a synthetic medium for Dictyostelium discoideum. PROCESS BIOCHEMISTRY. 2004;39(8):925-930.
    PUB | DOI | WoS
     
  • [41]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609051
    Voß C, Schmidt T, Schleef M, Friehs K, Flaschel E. Effect of ammonium chloride on plasmid DNA production in high cell density batch culture for biopharmaceutical use. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. 2004;79(1):57-62.
    PUB | DOI | WoS
     
  • [40]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608382
    Lu YH, Knol JC, Linskens MHK, Friehs K, van Haastert PJM, Flaschel E. Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium. JOURNAL OF BIOTECHNOLOGY. 2004;108(3):243-251.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [39]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606278
    Lu YH, Knol JC, Linskens MHK, Friehs K, van Haastert PJM, Flaschel E. Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2004;65(5):547-552.
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  • [38]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606443
    Lu YH, Beshay U, Friehs K, Flaschel E. Mass production of Dictyostelium discoideum in homogenous and hetergeneous cultivation systems. PROCESS BIOCHEMISTRY. 2004;39(12):1859-1870.
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  • [37]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609437
    Beshay U, Friehs K, Azzam AEM, Flaschel E. Analysis of the behaviour of Dictyostelium discoideum in immobilised state by means of continuous cultivation. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 2003;26(2):117-122.
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  • [36]
    2003 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1610736
    Schleef M, Voß C, Schmidt T, Flaschel E. Plasmid topology - An important factor influencing the performance of DNA drug delivery. JOURNAL OF LIPOSOME RESEARCH. 2003;13(1):82-83.
    PUB | WoS
     
  • [35]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1610824
    Beshay U, Friehs K, Azzam AEM, Flaschel E. Cultivation of Dictyostelium discoideum in immobilized form by colonization of porous supports. PROCESS BIOCHEMISTRY. 2003;38(11):1521-1529.
    PUB | DOI | WoS
     
  • [34]
    2003 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1610932
    Schleef M, Voß C, Schmidt T, Flaschel E. Plasmid vector stability in production, application and storage. JOURNAL OF GENE MEDICINE. 2003;5(3):S26-S26.
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  • [33]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609656
    Voß C, Schmidt T, Schleef M, Friehs K, Flaschel E. Production of supercoiled multimeric plasmid DNA for biopharmaceutical application. JOURNAL OF BIOTECHNOLOGY. 2003;105(3):205-213.
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  • [32]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609485
    Stephan M, Beshay U, Friehs K, Flaschel E. Influence of medium composition on growth behaviour of Dictyostelium discoideum for cultivation on axenic media. PROCESS BIOCHEMISTRY. 2003;39(3):333-343.
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  • [31]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880734
    Schierl F, Friehs K, Risse JM, Flaschel E. Herstellung von Mediumskomponenten aus mikrobieller Biomasse. Freiberger Forschungshefte. 2002;A 866:112-124.
    PUB
     
  • [30]
    2002 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1613125
    Hettwer J, Oldenburg H, Flaschel E. Enzymic routes to dihydroxyacetone phosphate or immediate precursors. In: Journal of Molecular Catalysis B: Enzymatic. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC. Vol 19. ELSEVIER SCIENCE BV; 2002: 215-222.
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  • [29]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613472
    Miksch G, Kleist S, Friehs K, Flaschel E. Overexpression of the phytase from Escherichia coli and its extracellular production in bioreactors. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2002;59(6):685-694.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [28]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880242
    Risse JM, Friehs K, Flaschel E. Recycling of Biomass Resulting from Fermentation Processes with Bacillus licheniformis. Chem. Eng. Technol. 2001;24(10):141-145.
    PUB
     
  • [27]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616886
    Schroter K, Flaschel E, Pühler A, Becker A. Xanthomonas campestris pv. campestris secretes the endoglucanases ENGXCA and ENGXCB: construction of an endoglucanase-deficient mutant for industrial xanthan production. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2001;55(6):727-733.
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  • [26]
    2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1880243
    Miksch G, Flaschel E. Secretion of homologous and heterologous recombinant proteins in Escherichia coli and other gram-negative bacteria by using a new secretion system. In: Merten O-W, Mattanovich D, Lang C, eds. Recombinant protein production with prokaryotic and eukaryotic cells - A comparative view on host physiology. Selected articles from the meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th-8th October 2000. Dordrecht: Kluwer Academic Publishers; 2001: 347-358.
    PUB
     
  • [25]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619389
    Risse JM, Friehs K, Flaschel E. Biomasserückführung am Beispiel Bacillus licheniformis. CHEMIE INGENIEUR TECHNIK. 2000;72(7):750-754.
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  • [24]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621141
    Baier R, Schiene K, Kohring B, Flaschel E, Niehaus K. Alfalfa and tobacco cells react differently to chitin oligosaccharides and Sinorhizobium meliloti nodulation factors. PLANTA. 1999;210(1):157-164.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [23]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621612
    Schmidt T, Friehs K, Schleef M, Voß C, Flaschel E. Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis. ANALYTICAL BIOCHEMISTRY. 1999;274(2):235-240.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [22]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622862
    Miksch G, Neitzel R, Friehs K, Flaschel E. High-level expression of a recombinant protein in Klebsiella planticola owing to induced secretion into the culture medium. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 1999;51(5):627-632.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [21]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1625697
    Friehs K, Schierl F, Flaschel E. Reprocessing of bacterial biomass for recycling as a medium component in fermentation processes. CHEMIE INGENIEUR TECHNIK. 1998;70(4):435-437.
    PUB | DOI | WoS
     
  • [20]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626311
    Margot A, Flaschel E, Renken A. Development of a continuously operated reactor for the limited hydrolysis of whey protein by trypsin. PROCESS BIOCHEMISTRY. 1998;33(2):125-131.
    PUB | DOI | WoS
     
  • [19]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626283
    Huneke FU, Flaschel E. Behaviour of liquid/liquid/solid three-phase fixed bed reactors with application in biocatalysis. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. 1998;71(3):213-222.
    PUB | DOI | WoS
     
  • [18]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1637759
    Miksch G, Neitzel R, Fiedler E, Friehs K, Flaschel E. Extracellular production of a hybrid beta-glucanase from Bacillus by Escherichia coli under different cultivation conditions in shaking cultures and bioreactors. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 1997;47(2):120-126.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [17]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636857
    Miksch G, Fiedler E, Dobrowolski P, Flaschel E. Controlled secretion into the culture medium of a hybrid beta-glucanase by Acetobacter methanolicus mediated by the kil gene of Escherichia coli located on a Tn5-derived transposon. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 1997;47(5):530-536.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [16]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628040
    Margot A, Flaschel E, Renken A. Empirical kinetic models for tryptic whey-protein hydrolysis. PROCESS BIOCHEMISTRY. 1997;32(3):217-223.
    PUB | DOI | WoS
     
  • [15]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626566
    Kohring B, Baier R, Niehaus K, Pühler A, Flaschel E. Production of nodulation factors by Rhizobium meliloti: fermentation, purification and characterization of glycolipids. GLYCOCONJUGATE JOURNAL. 1997;14(8):963-971.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [14]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627108
    Poppenborg L, Friehs K, Flaschel E. The green fluorescent protein is a versatile reporter for bioprocess monitoring. JOURNAL OF BIOTECHNOLOGY. 1997;58(2):79-88.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [13]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1638581
    Hentsch M, Warnery P, Renken A, Flaschel E. Study of the simultaneous partitioning of proteins and surfactant in reverse micellar two-phase systems - Potential impact upon purification efficiency. BIOSEPARATION. 1996;6(2):67-76.
    PUB | WoS
     
  • [12]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628395
    Schmidt T, Friehs K, Flaschel E. Rapid determination of plasmid copy number. JOURNAL OF BIOTECHNOLOGY. 1996;49(1-3):219-229.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [11]
    1996 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1639656
    Schmidt T, Friehs K, Flaschel E. Plasmid copy number as a process variable for fermentation control. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 1996;211:191-BIOT.
    PUB | WoS
     
  • [10]
    1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641313
    Flaschel E, Margot A, Dohmen M, Renken A. Conversion-Space Time Profiles of Stirred-Tank Reactors Continuously Fed with Reactants and Catalyst under Conditions of Strong Catalyst Deactivation. Chemical Engineering Science. 1995;50(7):1143-1147.
    PUB | DOI | WoS
     
  • [9]
    1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641188
    HENTSCH M, Flaschel E, RENKEN A. RADIOLABELED AOT FOR STUDIES OF THE PARTITIONING OF THE SURFACTANT DURING PROTEIN EXTRACTION BY MEANS OF REVERSE MICELLAR 2-PHASE SYSTEMS. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES. 1995;191(1):201-208.
    PUB | DOI | WoS
     
  • [8]
    1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1644182
    MARGOT A, Flaschel E, RENKEN A. CONTINUOUS MONITORING OF ENZYMATIC WHEY-PROTEIN HYDROLYSIS - CORRELATION OF BASE CONSUMPTION WITH SOLUBLE NITROGEN-CONTENT. PROCESS BIOCHEMISTRY. 1994;29(4):257-262.
    PUB | DOI | WoS
     
  • [7]
    1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641804
    HUNEKE FU, Flaschel E. PHASE DISTRIBUTION IN LIQUID-LIQUID 3-PHASE FIXED-BED REACTORS. CHEMIE INGENIEUR TECHNIK. 1994;66(12):1649-1651.
    PUB | DOI | WoS
     
  • [6]
    1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1643205
    Flaschel E, SCHAFFER T. NEW EVIDENCE FOR DIMERIZATION-DEPENDENCE OF THE ACTIVITY OF CANDIDA-RUGOSA LIPASE. In: Biocatalysis. BIOCATALYSIS. Vol 9. HARWOOD ACAD PUBL GMBH; 1994: 241-248.
    PUB | DOI | WoS
     
  • [5]
    1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1643820
    POPPENBORG L, Flaschel E. AFFINITY EXTRACTION OF PROTEINS BY MEANS OF REVERSE MICELLAR PHASES CONTAINING A METAL-CHELATING SURFACTANT. BIOTECHNOLOGY TECHNIQUES. 1994;8(5):307-312.
    PUB | DOI | WoS
     
  • [4]
    1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1646173 OA
    Flaschel E, Friehs K. Improvement of downstream processing of recombinant proteins by means of genetic engineering. Biotechnology Advances. 1993;11(1):31-77.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [3]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629782
    Hentsch M, Menoud P, Flaschel E, Renken A. The effect of temperature on the kinetics of a reverse micellar protein extraction process. BIOTECHNOLOGY TECHNIQUES. 1992;6(5):423-428.
    PUB | WoS
     
  • [2]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629787
    Hentsch M, Menoud P, Steiner L, Flaschel E, Renken A. Optimization of the surfactant (AOT) concentration in a reverse micellar extraction process. BIOTECHNOLOGY TECHNIQUES. 1992;6(4):359-364.
    PUB | DOI | WoS
     
  • [1]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1647759
    MARGOT A, RICHOZ C, Flaschel E, RENKEN A. INFLUENCE OF TRYPSIN DEACTIVATION ON THE HYDROLYSIS OF WHEY PROTEINS. CHEMIE INGENIEUR TECHNIK. 1992;64(6):551-553.
    PUB | DOI | WoS
     

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